Top 100 Fast-growings companies in Lysosome by Most Patent Filing In 5 Years in the world in 2018 – Discovery

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The Lysosome top 100 is Discovery PatSnap’ annual ranking of the top 100 Most Patent Filing In 5 Years Lysosome Fast-growings in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2018, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

A lysosome (/ˈlaɪsəˌsoʊm/) is a membrane-bound organelle found in many animal cells. They are spherical vesicles that contain hydrolytic enzymes that can break down many kinds of biomolecules. A lysosome has a specific composition, of both its membrane proteins, and its lumenal proteins. The lumen's pH (~4.5–5.0) is optimal for the enzymes involved in hydrolysis, analogous to the activity of the stomach. Besides degradation of polymers, the lysosome is involved in various cell processes, including secretion, plasma membrane repair, cell signaling, and energy metabolism.

1	Amicus Therapeutics, Inc.	New Jersey, United States	Pharmacological chaperone,Medicine,Health care, ...[+2]	Patent: 45
2	Shire Human Genetic Therapies, Inc.	Massachusetts, United States	Medicine	Patent: 44
3	BioMarin Pharmaceutical, Inc.	California, United States	Software development,Biopharmaceutical,Clinical trial, ...[+2]	Patent: 33
4	Regeneron Pharmaceuticals, Inc.	New York, United States	Monoclonal antibody,Clinical trial,Cholesterol, ...[+2]	Patent: 29
5	STARTUP Prevail Therapeutics, Inc.	New York, United States	Gene,Health care,Pharmacy and Therapeutics, ...[+2]	Patent: 24
6	JCR Pharmaceuticals Co., Ltd.	Hokkaido, Japan	Raw material,Drug,Medicine, ...[+2]	Patent: 22
7	Genzyme Corp.	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,Multiple sclerosis, ...[+2]	Patent: 20
8	Sarepta Therapeutics, Inc.	Massachusetts, United States	Pharmacy and Therapeutics,Health care,Approved drug, ...[+2]	Patent: 16
9	Murdoch University	Western Australia, Australia	Public university,Library science,Digital library, ...[+2]	Patent: 14
10	The University of California, San Francisco	California, United States	Nursing,Health care,Association (object-oriented programming), ...[+2]	Patent: 14
11	University of Washington	Washington, United States	Machine learning,Lecture hall,Energy storage, ...[+2]	Patent: 14
12	Regents of the University of California	California, United States	Working capital,Pathology,Companion diagnostic, ...[+2]	Patent: 14
13	Universitat Autònoma de Barcelona	Cataluña, Spain	Public university,Association (object-oriented programming),Cell therapy, ...[+2]	Patent: 14
14	Swedish Orphan Biovitrum AB	Sweden	Medicine,Clinical trial,Biotechnology, ...[+2]	Patent: 12
15	Angiochem, Inc.	Quebec, Canada	Drug,Medicine,Health care, ...[+2]	Patent: 12
16	Bayer Healthcare LLC	New Jersey, United States	Pharmaceutical medicine,Medicine,Computed tomography, ...[+2]	Patent: 12
17	Korea Research Institute of Bioscience & Biotechnlogy	Daejeon, South Korea	Biotechnology,Biology,Health care, ...[+2]	Patent: 12
18	BCN Peptides SA	Cataluña, Spain	Peptide,Chemical engineering,Retinopathy, ...[+2]	Patent: 12
19	Bayer HealthCare AG	Nordrhein-Westfalen, Germany	Health care,Diabetes Therapy,Immunoprotein, ...[+2]	Patent: 12
20	University Of Jinan	Shandong Sheng, China	Pinyin,Chemistry,Materials science, ...[+2]	Patent: 11
21	Alexion Pharmaceuticals, Inc.	Connecticut, United States	Health care,Biopharmaceutical,Clinical trial, ...[+2]	Patent: 11
22	Takeda Chemical Industries Ltd.	Japan	Pharmaceutical drug,Botanical drug,Herb	Patent: 10
23	Takeda Pharmaceutical Co., Ltd.	Osaka, Japan	Medicine,Health care,Clinical trial, ...[+2]	Patent: 10
24	Esteve Pharmaceuticals S.A.	Cataluña, Spain	Ophthalmology,Pathology,Pharmacy, ...[+2]	Patent: 9
25	Bristol-Myers Squibb FCT bêta, Inc.	Texas, United States	Health care,Biological pathway,Biopharmaceutical, ...[+2]	Patent: 9
26	ESTEVE	Cataluña, Spain	Drug,Medicine,Health care, ...[+2]	Patent: 9
27	STARTUP IntraBio Ltd.	Oxfordshire, United Kingdom	Clinical trial,Medicine,Drug, ...[+2]	Patent: 8
28	Bayer Pharma AG	Berlin, Germany	Medicine,Nuclear medicine,Andrology, ...[+2]	Patent: 8
29	PerkinElmer Health Sciences, Inc.	MA, US	Medicine	Patent: 8
30	STARTUP Ligandal, Inc.	New York, United States	CRISPR,Coronavirus disease 2019 (COVID-19),Cell therapy, ...[+2]	Patent: 7
31	University of Washington Center for Commercialization	WA, US		Patent: 7
32	Duke University	North Carolina, United States	Style guide,Typeface,Medicine, ...[+2]	Patent: 7
33	Ospedale San Raffaele Srl	Lombardia, Italy	Pathology,Health care,Hospitality industry, ...[+2]	Patent: 7
34	Valerion Therapeutics LLC	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,Alglucosidase alfa, ...[+2]	Patent: 7
35	Bayer Oy	Finland		Patent: 7
36	The Texas A&M University System	Texas, United States	University system,Asset management,Pension, ...[+2]	Patent: 7
37	Baylor College of Medicine	Texas, United States	Medical school,Medical education,Medicine, ...[+2]	Patent: 7
38	Hong Kong Baptist University	Hong Kong SAR, China	Tertiary institution,Chemistry,Cord blood, ...[+2]	Patent: 7
39	China Pharmaceutical University	Jiangsu Sheng, China	Pharmaceutical sciences,Chemistry,Retinitis, ...[+2]	Patent: 7
40	Eleva GmbH	Baden-Württemberg, Germany	Fabry's disease,Therapeutic protein,Technology transfer, ...[+2]	Patent: 7
41	Bayer AG	Nordrhein-Westfalen, Germany	Health care,Biology,Chemical engineering, ...[+2]	Patent: 7
42	The Children's Medical Center Corp.	Massachusetts, United States	Internet of Things,Health care,Hospitality industry	Patent: 7
43	The Hong Kong University of Science & Technology	Hong Kong SAR, China	World map,Contact lens solutions,Computer science, ...[+2]	Patent: 6
44	Nanjing Mingde New Drug Research and Development Co., Ltd.			Patent: 6
45	Kumamoto University	Kumamoto, Japan	Brain monitoring,Dementia,Medicine, ...[+2]	Patent: 6
46	Icahn School of Medicine at Mount Sinai	New York, United States		Patent: 6
47	Vanderbilt University	Tennessee, United States	Professional degree,Health care,Publication, ...[+2]	Patent: 6
48	Rush University Medical Center	Illinois, United States	Health care,Surgical Specialty,Medicine, ...[+2]	Patent: 6
49	Southeast University	Jiangsu Sheng, China	Mechanical engineering,Molecular beam epitaxy,Retinitis, ...[+2]	Patent: 5
50	Protalix Ltd.	Haifa, Israel		Patent: 5
51	University of South Australia	South Australia, Australia	Sewing needle,Biopsy needles,Medicine, ...[+2]	Patent: 5
52	Marker Gene Technologies, Inc.	Oregon, United States	Biotechnology,Microarray,Marker gene, ...[+2]	Patent: 5
53	University of Adelaide	South Australia, Australia	Public university,City centre,Microbiome, ...[+2]	Patent: 5
54	Dana-Farber Cancer Institute, Inc.	Massachusetts, United States	Pediatric cancer,Substance abuse,Robotics, ...[+2]	Patent: 5
55	New York University	New York, United States	Journalism,Professional studies,Medicine, ...[+2]	Patent: 5
56	Shanxi University	Shanxi Sheng, China	Pinyin,Public university,Chemistry, ...[+2]	Patent: 5
57	Anhui University	Anhui Sheng, China	Pinyin,Literature,Computer science, ...[+2]	Patent: 5
58	Oklahoma Medical Research Foundation	Oklahoma, United States	Medical research,Health care,Biology, ...[+2]	Patent: 4
59	Sichuan University	Sichuan Sheng, China	Monoclonal antibody,Cancer immunotherapy,Immunotherapy, ...[+2]	Patent: 4
60	The University of Texas at Austin	Texas, United States	Undergraduate education,Career development,Association (object-oriented programming), ...[+2]	Patent: 4
61	St. Jude Children's Research Hospital, Inc.	Tennessee, United States	Health care,Hospitality industry,Genomics, ...[+2]	Patent: 4
62	Board of Trustees of the Leland Stanford Junior University	California, United States		Patent: 4
63	Sangamo Therapeutics, Inc.	California, United States	Cell,Pharmacy and Therapeutics,Genomics, ...[+2]	Patent: 4
64	University of Iowa Research Foundation	Iowa, United States	Gene delivery,Expression vector,Viral vector, ...[+2]	Patent: 4
65	Yantai Heyuanaidisi Biomedical Technology Co Ltd	China		Patent: 4
66	Dalian Institute of Chemical Physics Chinese Academy of Sciences	Liaoning Sheng, China	Chemistry,Inorganic chemistry,Catalysis, ...[+2]	Patent: 4
67	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	Patent: 4
68	University of Massachusetts	Massachusetts, United States		Patent: 4
69	Merck Sharp & Dohme Corp.	New Jersey, United States	Prescription drug,Medicine,Stroke, ...[+2]	Patent: 4
70	STARTUP Evox Therapeutics Ltd.	Oxfordshire, United Kingdom	Exosome,Health care,Genomics, ...[+2]	Patent: 4
71	Riken Corp.	Saitama, Japan	Social network,Tappet,Piston ring, ...[+2]	Patent: 4
72	The University of Texas at Arlington	Texas, United States	Library science,Community engagement,Critical thinker, ...[+2]	Patent: 4
73	Rexahn Pharmaceuticals, Inc.	United States	Medicine,Medical equipment,Drug, ...[+2]	Patent: 3
74	UbiVac, Inc.	Oregon, United States	Immunotherapy,Medicine,Wellness Programs, ...[+2]	Patent: 3
75	biOasis Technologies, Inc.	British Columbia, Canada	Biopharmaceutical,Brain cancers,Biomedicine, ...[+2]	Patent: 3
76	University of Stellenbosch	South Africa	Academic community,Atmosphere,Knee implant, ...[+2]	Patent: 3
77	Dojindo Laboratories	Japan		Patent: 3
78	Northwest University	Washington, United States	Chemistry,Inorganic chemistry,Geochemistry, ...[+2]	Patent: 3
79	Oslo universitetssykehus HF	Oslo, Norway	Medical research,Health care,Oncology, ...[+2]	Patent: 3
80	Ambrx, Inc.	California, United States	Biology,Pharmacy and Therapeutics,Dosing Frequency, ...[+2]	Patent: 3
81	Board of Regents of The University of Oklahoma	Oklahoma, United States	Radio broadcasting station,Radio broadcasting,Broadcasting	Patent: 3
82	Cincinnati Children's Hospital Medical Center	Ohio, United States	Health care,Pediatric trauma,Neonatology, ...[+2]	Patent: 3
83	Zhengzhou University	Shanxi Sheng, China	Academic Training,Educational institution,Graduate degree, ...[+2]	Patent: 3
84	Xiamen University	Fujian Sheng, China	BCG vaccine,HIV vaccine,Conjugate vaccine, ...[+2]	Patent: 3
85	ICCAS	Beijing Shi, China	Chemical engineering	Patent: 3
86	Universidade de Vigo	Spain	Knowledge area,University system,City centre, ...[+2]	Patent: 3
87	Fundación Biomédica Galicia Sur	GA, ES		Patent: 3
88	Nihon Shokuhin Kako Co., Ltd.	Tokyo, Japan	Starch,Food industry,Food processing, ...[+2]	Patent: 3
89	Fourth Military Medical University	Hunan Sheng, China	National security,BCG vaccine,HIV vaccine, ...[+2]	Patent: 3
90	FUJIFILM Corp.	Tokyo, Japan	Photography,Medical imaging,Computer hardware, ...[+2]	Patent: 3
91	The Johns Hopkins University	United States	History of the United States,Bequest,Medicine, ...[+2]	Patent: 3
92	Huazhong University of Science & Technology	Hubei Sheng, China	Education development,Cell therapy,Drug repositioning, ...[+2]	Patent: 2
93	Yonsei Industry-Academic Cooperation Foundation	Seoul, South Korea		Patent: 2
94	Vakzine Projekt Management GmbH	Niedersachsen, Germany	Small molecule,Medicine,Drug development, ...[+2]	Patent: 2
95	National University Corp. Tokyo Medical & Dental University	Japan		Patent: 2
96	Tianjin Medical University	Tianjin Shi, China	Heart-Lung Machine,Medical institution,Pinyin, ...[+2]	Patent: 2
97	Postech Academy - Industry Foundation	South Korea		Patent: 2
98	The Hong Kong Polytechnic University	Hong Kong SAR, China	Knowledge management,Mandate,Mechanical engineering, ...[+2]	Patent: 2
99	Yanbian University	Jilin Sheng, China	Chemistry,Biology,Medicine, ...[+2]	Patent: 2
100	Synageva BioPharma Corp.	Massachusetts, United States	Botanical drug,Herb,Accelerated atherosclerosis, ...[+2]	Patent: 2