Top 100 Fast-growings companies in Lysosome by Most Patent Filing In 5 Years in the world in 2019 – Discovery

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The Lysosome top 100 is Discovery PatSnap’ annual ranking of the top 100 Most Patent Filing In 5 Years Lysosome Fast-growings in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2019, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

A lysosome (/ˈlaɪsəˌsoʊm/) is a membrane-bound organelle found in many animal cells. They are spherical vesicles that contain hydrolytic enzymes that can break down many kinds of biomolecules. A lysosome has a specific composition, of both its membrane proteins, and its lumenal proteins. The lumen's pH (~4.5–5.0) is optimal for the enzymes involved in hydrolysis, analogous to the activity of the stomach. Besides degradation of polymers, the lysosome is involved in various cell processes, including secretion, plasma membrane repair, cell signaling, and energy metabolism.

1	Shire Human Genetic Therapies, Inc.	Massachusetts, United States	Medicine	Patent: 49
2	Regeneron Pharmaceuticals, Inc.	New York, United States	Monoclonal antibody,Clinical trial,Cholesterol, ...[+2]	Patent: 36
3	BioMarin Pharmaceutical, Inc.	California, United States	Software development,Biopharmaceutical,Clinical trial, ...[+2]	Patent: 33
4	Amicus Therapeutics, Inc.	New Jersey, United States	Pharmacological chaperone,Medicine,Health care, ...[+2]	Patent: 31
5	JCR Pharmaceuticals Co., Ltd.	Hokkaido, Japan	Raw material,Drug,Medicine, ...[+2]	Patent: 31
6	STARTUP Prevail Therapeutics, Inc.	New York, United States	Gene,Health care,Pharmacy and Therapeutics, ...[+2]	Patent: 26
7	The University of California, San Francisco	California, United States	Nursing,Health care,Association (object-oriented programming), ...[+2]	Patent: 24
8	Regents of the University of California	California, United States	Working capital,Pathology,Companion diagnostic, ...[+2]	Patent: 24
9	Universitat Autònoma de Barcelona	Cataluña, Spain	Public university,Association (object-oriented programming),Cell therapy, ...[+2]	Patent: 19
10	University Of Jinan	Shandong Sheng, China	Pinyin,Chemistry,Materials science, ...[+2]	Patent: 17
11	Esteve Pharmaceuticals S.A.	Cataluña, Spain	Ophthalmology,Pathology,Pharmacy, ...[+2]	Patent: 15
12	ESTEVE	Cataluña, Spain	Drug,Medicine,Health care, ...[+2]	Patent: 15
13	Genzyme Corp.	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,Multiple sclerosis, ...[+2]	Patent: 14
14	Swedish Orphan Biovitrum AB	Sweden	Medicine,Clinical trial,Biotechnology, ...[+2]	Patent: 13
15	Takeda Chemical Industries Ltd.	Japan	Pharmaceutical drug,Botanical drug,Herb	Patent: 12
16	University of Massachusetts	Massachusetts, United States		Patent: 12
17	University of Washington	Washington, United States	Machine learning,Lecture hall,Energy storage, ...[+2]	Patent: 12
18	Takeda Pharmaceutical Co., Ltd.	Osaka, Japan	Medicine,Health care,Clinical trial, ...[+2]	Patent: 12
19	Astellas Pharma, Inc.	Tokyo, Japan	Health care,Clinical trial,Diabetic complication, ...[+2]	Patent: 11
20	Alexion Pharmaceuticals, Inc.	Connecticut, United States	Health care,Biopharmaceutical,Clinical trial, ...[+2]	Patent: 11
21	Board of Trustees of the Leland Stanford Junior University	California, United States		Patent: 10
22	China Pharmaceutical University	Jiangsu Sheng, China	Pharmaceutical sciences,Chemistry,Retinitis, ...[+2]	Patent: 10
23	Asklepios BioPharmaceutical, Inc.	North Carolina, United States	Biopharmaceutical,Health care,Gene delivery, ...[+2]	Patent: 9
24	Baylor College of Medicine	Texas, United States	Medical school,Medical education,Medicine, ...[+2]	Patent: 9
25	Duke University	North Carolina, United States	Style guide,Typeface,Medicine, ...[+2]	Patent: 8
26	Trustees of the University of Pennsylvania	Pennsylvania, United States	Academic Training,Educational institution,Graduate degree, ...[+2]	Patent: 8
27	STARTUP IntraBio Ltd.	Oxfordshire, United Kingdom	Clinical trial,Medicine,Drug, ...[+2]	Patent: 8
28	Yantai Heyuanaidisi Biomedical Technology Co Ltd	China		Patent: 8
29	Shanxi University	Shanxi Sheng, China	Pinyin,Public university,Chemistry, ...[+2]	Patent: 8
30	Sarepta Therapeutics, Inc.	Massachusetts, United States	Pharmacy and Therapeutics,Health care,Approved drug, ...[+2]	Patent: 8
31	Bayer Pharma AG	Berlin, Germany	Medicine,Nuclear medicine,Andrology, ...[+2]	Patent: 8
32	Rush University Medical Center	Illinois, United States	Health care,Surgical Specialty,Medicine, ...[+2]	Patent: 8
33	STARTUP Ligandal, Inc.	New York, United States	CRISPR,Coronavirus disease 2019 (COVID-19),Cell therapy, ...[+2]	Patent: 7
34	The Hong Kong University of Science & Technology	Hong Kong SAR, China	World map,Contact lens solutions,Computer science, ...[+2]	Patent: 7
35	Ospedale San Raffaele Srl	Lombardia, Italy	Pathology,Health care,Hospitality industry, ...[+2]	Patent: 7
36	Bayer Oy	Finland		Patent: 7
37	The Texas A&M University System	Texas, United States	University system,Asset management,Pension, ...[+2]	Patent: 7
38	Murdoch University	Western Australia, Australia	Public university,Library science,Digital library, ...[+2]	Patent: 7
39	Korea Research Institute of Bioscience & Biotechnlogy	Daejeon, South Korea	Biotechnology,Biology,Health care, ...[+2]	Patent: 7
40	Hong Kong Baptist University	Hong Kong SAR, China	Tertiary institution,Chemistry,Cord blood, ...[+2]	Patent: 7
41	Boston University	Massachusetts, United States	Law library,Medicine,Cephalosporin, ...[+2]	Patent: 7
42	Protec Co., Ltd.	South Korea	Semiconductor,Pneumatic cylinder,Electronic component, ...[+1]	Patent: 7
43	Eleva GmbH	Baden-Württemberg, Germany	Fabry's disease,Therapeutic protein,Technology transfer, ...[+2]	Patent: 7
44	Bayer AG	Nordrhein-Westfalen, Germany	Health care,Biology,Chemical engineering, ...[+2]	Patent: 7
45	The Children's Medical Center Corp.	Massachusetts, United States	Internet of Things,Health care,Hospitality industry	Patent: 7
46	Southeast University	Jiangsu Sheng, China	Mechanical engineering,Molecular beam epitaxy,Retinitis, ...[+2]	Patent: 6
47	biOasis Technologies, Inc.	British Columbia, Canada	Biopharmaceutical,Brain cancers,Biomedicine, ...[+2]	Patent: 6
48	Denali Therapeutics, Inc.	California, United States	Biotechnology,Pharmacy and Therapeutics,Biological process, ...[+2]	Patent: 6
49	Zhengzhou University	Shanxi Sheng, China	Academic Training,Educational institution,Graduate degree, ...[+2]	Patent: 6
50	Vanderbilt University	Tennessee, United States	Professional degree,Health care,Publication, ...[+2]	Patent: 6
51	STARTUP NEUWAY Pharma GmbH	Nordrhein-Westfalen, Germany	Health care,Progressive multifocal leukoencephalopathy,Metachromatic leukodystrophy, ...[+2]	Patent: 6
52	Anhui University	Anhui Sheng, China	Pinyin,Literature,Computer science, ...[+2]	Patent: 6
53	Sichuan University	Sichuan Sheng, China	Monoclonal antibody,Cancer immunotherapy,Immunotherapy, ...[+2]	Patent: 5
54	Marker Gene Technologies, Inc.	Oregon, United States	Biotechnology,Microarray,Marker gene, ...[+2]	Patent: 5
55	Nanjing Mingde New Drug Research and Development Co., Ltd.			Patent: 5
56	Dana-Farber Cancer Institute, Inc.	Massachusetts, United States	Pediatric cancer,Substance abuse,Robotics, ...[+2]	Patent: 5
57	Angiochem, Inc.	Quebec, Canada	Drug,Medicine,Health care, ...[+2]	Patent: 5
58	PerkinElmer Health Sciences, Inc.	MA, US	Medicine	Patent: 5
59	Seoul University Industry Academic Cooperation Foundation	South Korea		Patent: 5
60	Oklahoma Medical Research Foundation	Oklahoma, United States	Medical research,Health care,Biology, ...[+2]	Patent: 4
61	Protalix Ltd.	Haifa, Israel		Patent: 4
62	The University of Texas at Austin	Texas, United States	Undergraduate education,Career development,Association (object-oriented programming), ...[+2]	Patent: 4
63	St. Jude Children's Research Hospital, Inc.	Tennessee, United States	Health care,Hospitality industry,Genomics, ...[+2]	Patent: 4
64	Kumamoto University	Kumamoto, Japan	Brain monitoring,Dementia,Medicine, ...[+2]	Patent: 4
65	Icahn School of Medicine at Mount Sinai	New York, United States		Patent: 4
66	Dalian Institute of Chemical Physics Chinese Academy of Sciences	Liaoning Sheng, China	Chemistry,Inorganic chemistry,Catalysis, ...[+2]	Patent: 4
67	STARTUP Evox Therapeutics Ltd.	Oxfordshire, United Kingdom	Exosome,Health care,Genomics, ...[+2]	Patent: 4
68	ICCAS	Beijing Shi, China	Chemical engineering	Patent: 4
69	Riken Corp.	Saitama, Japan	Social network,Tappet,Piston ring, ...[+2]	Patent: 4
70	Sun Yat-Sen University	Guangdong Sheng, China	Management science,Square kilometer,Social science, ...[+2]	Patent: 4
71	The University of Texas at Arlington	Texas, United States	Library science,Community engagement,Critical thinker, ...[+2]	Patent: 4
72	UbiVac, Inc.	Oregon, United States	Immunotherapy,Medicine,Wellness Programs, ...[+2]	Patent: 3
73	University of Washington Center for Commercialization	WA, US		Patent: 3
74	Yanbian University	Jilin Sheng, China	Chemistry,Biology,Medicine, ...[+2]	Patent: 3
75	University of Stellenbosch	South Africa	Academic community,Atmosphere,Knee implant, ...[+2]	Patent: 3
76	Dojindo Laboratories	Japan		Patent: 3
77	Northwest University	Washington, United States	Chemistry,Inorganic chemistry,Geochemistry, ...[+2]	Patent: 3
78	Oslo universitetssykehus HF	Oslo, Norway	Medical research,Health care,Oncology, ...[+2]	Patent: 3
79	Ambrx, Inc.	California, United States	Biology,Pharmacy and Therapeutics,Dosing Frequency, ...[+2]	Patent: 3
80	Beijing Normal University	Beijing Shi, China	Teacher education,Literature,Chemistry, ...[+2]	Patent: 3
81	Sangamo Therapeutics, Inc.	California, United States	Cell,Pharmacy and Therapeutics,Genomics, ...[+2]	Patent: 3
82	Hokkaido University	Hokkaido, Japan	Biology,Chemistry,Medicine, ...[+2]	Patent: 3
83	University of Leiden	Zuid-Holland, Netherlands		Patent: 3
84	The Institute of Myology	IF, FR		Patent: 3
85	University of Iowa Research Foundation	Iowa, United States	Gene delivery,Expression vector,Viral vector, ...[+2]	Patent: 3
86	Institut National de la Santé et de la Recherche Médicale	Île-de-France, France	Public health,Genomics,Antisense therapy, ...[+2]	Patent: 3
87	Board of Regents of The University of Oklahoma	Oklahoma, United States	Radio broadcasting station,Radio broadcasting,Broadcasting	Patent: 3
88	Cincinnati Children's Hospital Medical Center	Ohio, United States	Health care,Pediatric trauma,Neonatology, ...[+2]	Patent: 3
89	University of Charles	Czechia		Patent: 3
90	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	Patent: 3
91	Merck Sharp & Dohme Corp.	New Jersey, United States	Prescription drug,Medicine,Stroke, ...[+2]	Patent: 3
92	Bayer Healthcare LLC	New Jersey, United States	Pharmaceutical medicine,Medicine,Computed tomography, ...[+2]	Patent: 3
93	STARTUP INSERM Limoges		E-commerce	Patent: 3
94	Xiamen University	Fujian Sheng, China	BCG vaccine,HIV vaccine,Conjugate vaccine, ...[+2]	Patent: 3
95	Georgetown University	District of Columbia, United States	Basketball,Medicine,Biotechnology, ...[+2]	Patent: 3
96	Universidade de Vigo	Spain	Knowledge area,University system,City centre, ...[+2]	Patent: 3
97	The University of Central Florida Research Foundation, Inc.	United States	Asset management,Impact investing,Social Welfare	Patent: 3
98	Fundación Biomédica Galicia Sur	GA, ES		Patent: 3
99	Changzhou University	Jiangsu Sheng, China		Patent: 3
100	University of Utah Research Foundation	Utah, United States	Dissemination,Humanity,Cognitive development, ...[+2]	Patent: 3