Top 100 Fast-growings companies in Proline by Most Patent Filing In 3 Years in the world in 2018 – Discovery

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The Proline top 100 is Discovery PatSnap’ annual ranking of the top 100 Most Patent Filing In 3 Years Proline Fast-growings in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2018, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated NH₂⁺ form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO⁻ form under biological conditions), and a side chain pyrrolidine, classifying it as a nonpolar (at physiological pH), aliphatic amino acid. It is non-essential in humans, meaning the body can synthesize it from the non-essential amino acid L-glutamate. It is encoded by all the codons starting CC (CCU, CCC, CCA, and CCG).

1	XL-protein GmbH	Bayern, Germany	Medicine,Biopharmaceutical,Drug development, ...[+2]	Patent: 19
2	Jiangnan University	Jiangsu Sheng, China	Pinyin,Chemistry,Biochemistry, ...[+2]	Patent: 17
3	Guangzhou Bosma Optoelectronic Technology Co. Ltd.	Guangdong Sheng, China	Computer hardware,Electronics,Semiconductor, ...[+1]	Patent: 17
4	BONAC Corp.	Fukuoka, Japan	Nucleic acid,Medicine,Chemical engineering, ...[+2]	Patent: 15
5	Suntory Beverage & Food Ltd.	Tokyo, Japan	Mineral water,Ethanol,Food industry, ...[+2]	Patent: 15
6	Technische Universität München	Bayern, Germany	Entrepreneurial spirit,Nutrition,Biological membrane, ...[+2]	Patent: 15
7	Sundory Co. Ltd.	Japan		Patent: 15
8	Oxford University Innovation Ltd.	Oxfordshire, United Kingdom	Technology transfer,Angel investor,Ecosystem, ...[+2]	Patent: 15
9	Osaka University	Osaka, Japan	Public university,Knowledge management,Chemistry, ...[+2]	Patent: 14
10	Glaxo Group Ltd.	Hounslow, United Kingdom	Food products,Medicine,Health care	Patent: 14
11	The a2 Milk Co. Ltd.	Auckland, New Zealand	Infant formula,Food industry,Medicine, ...[+2]	Patent: 14
12	STARTUP Nuritas Ltd.	Dublin, Ireland	Artificial intelligence,Data mining,Peptide, ...[+2]	Patent: 13
13	The Institute of Genetics & Developmental Biology	Beijing Shi, China		Patent: 13
14	Hanmi Pharmaceutical Co., Ltd.	South Korea	Medicine,Health care,Drug development, ...[+2]	Patent: 12
15	JCR Pharmaceuticals Co., Ltd.	Hokkaido, Japan	Raw material,Drug,Medicine, ...[+2]	Patent: 12
16	Excivion Ltd.	Massachusetts, United States	Biotechnology,Bionics,Blood cell, ...[+2]	Patent: 11
17	AmtixBio Co., Ltd.			Patent: 10
18	Fuji Oil Holdings, Inc.	Osaka, Japan	Soy protein,Food processing,Textured vegetable protein, ...[+2]	Patent: 10
19	Fuji Oil Co. Ltd. (Osaka)	Osaka, Japan	Agriculture,Fertilizer,Animal fat, ...[+2]	Patent: 10
20	Institut National de la Santé et de la Recherche Médicale	Île-de-France, France	Public health,Genomics,Antisense therapy, ...[+2]	Patent: 10
21	University of Tokyo	Tokyo, Japan	Biology,Chemistry,Biochemistry, ...[+2]	Patent: 10
22	STARTUP INSERM Limoges		E-commerce	Patent: 10
23	Octapharma AG	Schwyz, Switzerland	Medicine,Health care,Collective responsibility, ...[+2]	Patent: 9
24	Jazz Pharmaceuticals Ireland Ltd.	Dublin, Ireland	Biopharmaceutical,Medicine	Patent: 9
25	University of Strasbourg	Alsace, France	Fields Medal,Diffusion MRI,Neuroimaging, ...[+2]	Patent: 9
26	Koninklijke DSM NV	Netherlands	Animal nutrition,Health care,Biology, ...[+2]	Patent: 9
27	Virometix AG	Zürich, Switzerland	Medicine,Health care,Cancer vaccine, ...[+2]	Patent: 9
28	Merz Pharma GmbH & Co. KGaA	Sachsen, Germany	Psychiatry,Neurology,Breast implant, ...[+2]	Patent: 9
29	University of Nebraska	Nebraska, United States		Patent: 8
30	UAB Research Foundation	Alabama, United States	Biotechnology,Agriculture,Fishery, ...[+2]	Patent: 8
31	NovMetaPharma Co., Ltd.	Kangwŏn-do, South Korea	Medicine,Drug,Antidiabetic agents, ...[+2]	Patent: 8
32	University of Zurich	Zürich, Switzerland	Structural biology,Neuroscience,Public sector, ...[+2]	Patent: 8
33	Senju Pharmaceutical Co., Ltd.	Osaka, Japan	Drug,Glaucoma,Allergy, ...[+2]	Patent: 8
34	Boehringer Ingelheim Animal Health USA, Inc.	United States	Medicine,Beta cell,Classical swine fever, ...[+2]	Patent: 8
35	Research Triangle Institute	North Carolina, United States	Education curriculum,International development,Medicine, ...[+2]	Patent: 7
36	Intervet International BV	Noord-Brabant, Netherlands	Fertility management,Medicine,Feed additive	Patent: 7
37	Kyushu University	Fukuoka, Japan	Cultural studies,Knowledge management,Public university, ...[+2]	Patent: 7
38	Shiseido Co., Ltd.	Tokyo, Japan	Cosmetics,Elixir,Personal Care Product, ...[+2]	Patent: 7
39	Huazhong Agricultural University	Hubei Sheng, China	Agronomy,Basic science,Agricultural science, ...[+2]	Patent: 7
40	Société des Produits Nestlé SA	Vaud, Switzerland	Food industry	Patent: 7
41	F. Hoffmann-La Roche Ltd.	Switzerland	Medicine,Health care,Drug, ...[+2]	Patent: 7
42	Ajinomoto Co., Inc.	Tokyo, Japan	Seasoning,Amino acid,Food processing, ...[+2]	Patent: 7
43	Sandoz AG	Switzerland	Botanical drug,Herb	Patent: 6
44	Unilever IP Holdings BV	Netherlands		Patent: 6
45	Otsuka Pharmaceutical Factory, Inc.	Tokushima, Japan	Parenteral nutrition,Human nutrition,Drug, ...[+2]	Patent: 6
46	Shanghai Institute of Materia Medica Chinese Academy of Sciences	Shanghai Shi, China	Tocilizumab,Rituximab,Toll-like receptor, ...[+2]	Patent: 6
47	Enanta Pharmaceuticals, Inc.	Massachusetts, United States	Medicine,Health care,Protease, ...[+2]	Patent: 6
48	Artelo Biosciences, Inc.	California, United States	Endocannabinoid system,Biology,Biomedicine, ...[+2]	Patent: 6
49	Kyoto University	Kyoto, Japan	Gauss,Stem cell,Chemistry, ...[+2]	Patent: 5
50	API Corp.	Fukuoka, Japan	Medicine,Pharmaceutical formulation,Fine chemical, ...[+1]	Patent: 5
51	Uniwersytet Medyczny w Bialymstoku	PD, PL	Bioinformatics,Medicine,Internal medicine, ...[+2]	Patent: 5
52	Calysta, Inc.	California, United States	Petroleum industry,Fish meal,Synthetic Genes, ...[+2]	Patent: 5
53	Hybio Pharmaceutical Co.. Ltd.	Guangdong Sheng, China	Drug,Health care,Gastrointestinal cancer, ...[+2]	Patent: 5
54	Unilever NV	Zuid-Holland, Netherlands	COLA (software architecture),Soft drink,Deodorant, ...[+2]	Patent: 5
55	Nestlé SA	Vaud, Switzerland	Ice cream,Nutrition,Cosmetics, ...[+2]	Patent: 4
56	Takeuchi Co. Ltd.	Japan	Automation,Manufacturing engineering,Industrial engineering, ...[+2]	Patent: 4
57	DKK-TOA Corp.	Tokyo, Japan	Sales management,Electronics,Dredging, ...[+2]	Patent: 4
58	Amgen, Inc.	California, United States	Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER, ...[+2]	Patent: 4
59	Tianjin University	Guangdong Sheng, China	Radio-frequency identification,Coronavirus disease 2019 (COVID-19),Pinyin, ...[+2]	Patent: 4
60	Guandong Institute of Microbiology	Guangdong Sheng, China	Microbiology	Patent: 4
61	Conopco, Inc.	NJ, US	Lotion	Patent: 4
62	AFFiRiS AG	Niederösterreich, Austria	Medicine,Health care,Peptide, ...[+2]	Patent: 4
63	Ocean University of China	Fujian Sheng, China	Fishery,Pinyin,Social science, ...[+2]	Patent: 4
64	Yangzhou University	Jiangsu Sheng, China	Pinyin,Biology,Chemistry, ...[+2]	Patent: 4
65	National Center of Neurology & Psychiatry	Tokyo, Japan	Neurology,Developmental disorder	Patent: 4
66	Norwegian University of Science & Technology	Sør-Trøndelag, Norway	Endoscopy,Endoscope,Capsule Endoscopes, ...[+2]	Patent: 4
67	Sun Pharmaceutical Industries Ltd.	Maharashtra, India	Inhaler,Drug,Medicine, ...[+2]	Patent: 4
68	Nestec SA	Vaud, Switzerland	Enzyme,Nutrition,Food industry, ...[+1]	Patent: 4
69	SEPPIC SA	Île-de-France, France	Cosmetics,Chemical engineering,Biological product, ...[+2]	Patent: 4
70	Tianjin University of Science & Technology	Guangdong Sheng, China	Chemistry,Biochemistry,Chromatography, ...[+2]	Patent: 4
71	Kikkoman Corp.	Chiba, Japan	Seasoning,Food industry,Hyaluronic acid, ...[+2]	Patent: 4
72	Changzhou Pharmaceutical Factory Co., Ltd.	Jiangsu Sheng, China	Rosuvastatin,Medicine,Active ingredient, ...[+1]	Patent: 3
73	Aurobindo Pharma Ltd.	Andhra Pradesh, India	Antibiotics,Medicine,Central nervous system, ...[+2]	Patent: 3
74	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	Patent: 3
75	Fluoptics SAS	Rhône-Alpes, France	Medical imaging,Optical imaging,Health care, ...[+2]	Patent: 3
76	Peking University	Beijing Shi, China	Transliteration,Knowledge management,Monoclonal antibody, ...[+2]	Patent: 3
77	Hubei Grand Life Science & Technology Co., Ltd	Hubei Sheng, China	Taurine,Drug,Theanine, ...[+1]	Patent: 3
78	Kyoto Prefectural Public University Corp.	Kyoto, Japan		Patent: 3
79	Marine Biomedical Research Institute of Qingdao	China	Medical research,Oceanography,Nanotechnology, ...[+2]	Patent: 3
80	Agency for Science, Technology & Research	Central Singapore, Singapore	Cell therapy,Genome,Genomics, ...[+2]	Patent: 3
81	Hebei University	Guangdong Sheng, China	Pinyin,Chemistry,Materials science, ...[+2]	Patent: 3
82	East China University of Science & Technology	Shanghai Shi, China	Syngas,Biomass,Biofuel, ...[+2]	Patent: 3
83	Zhejiang University of Technology	Zhejiang Sheng, China	Pinyin,Mainland China,Chemistry, ...[+2]	Patent: 3
84	Bristol Myers Co.	New York, United States	Botanical drug,Herb	Patent: 3
85	Guizhou University	Guizhou Sheng, China	Pinyin,Chemistry,Biology, ...[+2]	Patent: 3
86	Tokyo Medical University	Tokyo, Japan	Medical school,Medicine,Bachelor's Degree, ...[+2]	Patent: 3
87	SAMHWA PAINTS INDUSTRIAL Co., Ltd.	South Korea	Coating,Polyester,Industrial engineering, ...[+2]	Patent: 3
88	3-D Matrix, Inc.	Massachusetts, United States	Health care,Self-assembling peptide,Wound healing, ...[+2]	Patent: 3
89	Yafei Shanghai Biomedical Technology Co. , Ltd.	Shanghai Shi, China	Biomedical technology	Patent: 3
90	Taiyuan University of Technology	Taiwan Province, China	Pinyin,Materials science,Chemistry, ...[+2]	Patent: 3
91	Industry Foundation of Chonnam National University	South Korea	Asset management,Impact investing,Social Welfare	Patent: 3
92	University of Warwick	Coventry, United Kingdom	Medical school,Horticulture,Basilar-Type Migraine, ...[+2]	Patent: 3
93	Kyoto Institute of Technology	Kyoto, Japan	Sericulture,Materials science,Chemistry, ...[+2]	Patent: 3
94	Astellas Pharma, Inc.	Tokyo, Japan	Health care,Clinical trial,Diabetic complication, ...[+2]	Patent: 3
95	Shanghai University	Shanghai Shi, China	Pinyin,Materials science,Computer science, ...[+2]	Patent: 3
96	Sysmex Corp.	Hokkaido, Japan	Clinical chemistry,Reagent,Medical equipment, ...[+2]	Patent: 3
97	Lonza Guangzhou Nansha Ltd.	Guangdong Sheng, China	Drug,Medicine	Patent: 3
98	CSL Behring GmbH	Hessen, Germany	Medicine	Patent: 2
99	Nanjing Goodagro Co. Ltd.	China		Patent: 2
100	Alsonex Pty Ltd.	Queensland, Australia	Biopharmaceutical,Neuroinflammation	Patent: 2