Top 100 Fast-growings companies in Proline by Most Patent Filing In 5 Years in the world in 2018 – Discovery

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The Proline top 100 is Discovery PatSnap’ annual ranking of the top 100 Most Patent Filing In 5 Years Proline Fast-growings in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2018, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated NH₂⁺ form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO⁻ form under biological conditions), and a side chain pyrrolidine, classifying it as a nonpolar (at physiological pH), aliphatic amino acid. It is non-essential in humans, meaning the body can synthesize it from the non-essential amino acid L-glutamate. It is encoded by all the codons starting CC (CCU, CCC, CCA, and CCG).

1	Koninklijke DSM NV	Netherlands	Animal nutrition,Health care,Biology, ...[+2]	Patent: 54
2	Glaxo Group Ltd.	Hounslow, United Kingdom	Food products,Medicine,Health care	Patent: 30
3	Jiangnan University	Jiangsu Sheng, China	Pinyin,Chemistry,Biochemistry, ...[+2]	Patent: 26
4	XL-protein GmbH	Bayern, Germany	Medicine,Biopharmaceutical,Drug development, ...[+2]	Patent: 22
5	DuPont Nutrition Biosciences ApS	Hovedstaden, Denmark	Food science,Medicine,Health care, ...[+2]	Patent: 20
6	University of Zurich	Zürich, Switzerland	Structural biology,Neuroscience,Public sector, ...[+2]	Patent: 18
7	The a2 Milk Co. Ltd.	Auckland, New Zealand	Infant formula,Food industry,Medicine, ...[+2]	Patent: 18
8	Guangzhou Bosma Optoelectronic Technology Co. Ltd.	Guangdong Sheng, China	Computer hardware,Electronics,Semiconductor, ...[+1]	Patent: 18
9	Virometix AG	Zürich, Switzerland	Medicine,Health care,Cancer vaccine, ...[+2]	Patent: 18
10	Amano Enzyme, Inc.	Nagano, Japan	Enzyme,Drug,Chemical engineering, ...[+2]	Patent: 17
11	Oxford University Innovation Ltd.	Oxfordshire, United Kingdom	Technology transfer,Angel investor,Ecosystem, ...[+2]	Patent: 17
12	Amgen, Inc.	California, United States	Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER, ...[+2]	Patent: 17
13	Technische Universität München	Bayern, Germany	Entrepreneurial spirit,Nutrition,Biological membrane, ...[+2]	Patent: 16
14	Suntory Beverage & Food Ltd.	Tokyo, Japan	Mineral water,Ethanol,Food industry, ...[+2]	Patent: 16
15	Sundory Co. Ltd.	Japan		Patent: 16
16	BONAC Corp.	Fukuoka, Japan	Nucleic acid,Medicine,Chemical engineering, ...[+2]	Patent: 15
17	STARTUP Nuritas Ltd.	Dublin, Ireland	Artificial intelligence,Data mining,Peptide, ...[+2]	Patent: 14
18	Norwegian University of Science & Technology	Sør-Trøndelag, Norway	Endoscopy,Endoscope,Capsule Endoscopes, ...[+2]	Patent: 14
19	Osaka University	Osaka, Japan	Public university,Knowledge management,Chemistry, ...[+2]	Patent: 14
20	Boehringer Ingelheim Animal Health USA, Inc.	United States	Medicine,Beta cell,Classical swine fever, ...[+2]	Patent: 13
21	The Institute of Genetics & Developmental Biology	Beijing Shi, China		Patent: 13
22	Société D'Etudes Dermatologiques SASU	Île-de-France, France	Colourant,Active ingredient,Cosmetics, ...[+2]	Patent: 13
23	Ajinomoto Co., Inc.	Tokyo, Japan	Seasoning,Amino acid,Food processing, ...[+2]	Patent: 13
24	Enanta Pharmaceuticals, Inc.	Massachusetts, United States	Medicine,Health care,Protease, ...[+2]	Patent: 12
25	University of Basel	Basel-Stadt, Switzerland	Zoology,Academic community,Proportion, ...[+2]	Patent: 12
26	JCR Pharmaceuticals Co., Ltd.	Hokkaido, Japan	Raw material,Drug,Medicine, ...[+2]	Patent: 12
27	Hanmi Pharmaceutical Co., Ltd.	South Korea	Medicine,Health care,Drug development, ...[+2]	Patent: 12
28	Kao Corp.	Tokyo, Japan	Cosmetics,Health care,Hair conditioner, ...[+2]	Patent: 11
29	Fuji Oil Holdings, Inc.	Osaka, Japan	Soy protein,Food processing,Textured vegetable protein, ...[+2]	Patent: 11
30	Fuji Oil Co. Ltd. (Osaka)	Osaka, Japan	Agriculture,Fertilizer,Animal fat, ...[+2]	Patent: 11
31	Excivion Ltd.	Massachusetts, United States	Biotechnology,Bionics,Blood cell, ...[+2]	Patent: 11
32	University of Tokyo	Tokyo, Japan	Biology,Chemistry,Biochemistry, ...[+2]	Patent: 11
33	F. Hoffmann-La Roche Ltd.	Switzerland	Medicine,Health care,Drug, ...[+2]	Patent: 11
34	AmtixBio Co., Ltd.			Patent: 10
35	Jiangsu Hengrui Pharmaceuticals Co., Ltd.	Jiangsu Sheng, China	Drug,Health care,Antineoplastic Drugs, ...[+2]	Patent: 10
36	Geo-Poland Sp zoo	Greater Poland, Poland		Patent: 10
37	Société des Produits Nestlé SA	Vaud, Switzerland	Food industry	Patent: 10
38	Institut National de la Santé et de la Recherche Médicale	Île-de-France, France	Public health,Genomics,Antisense therapy, ...[+2]	Patent: 10
39	STARTUP INSERM Limoges		E-commerce	Patent: 10
40	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	Patent: 9
41	Bristol Myers Co.	New York, United States	Botanical drug,Herb	Patent: 9
42	Ares Trading SA	Switzerland		Patent: 9
43	Merz Pharma GmbH & Co. KGaA	Sachsen, Germany	Psychiatry,Neurology,Breast implant, ...[+2]	Patent: 9
44	Octapharma AG	Schwyz, Switzerland	Medicine,Health care,Collective responsibility, ...[+2]	Patent: 9
45	Jazz Pharmaceuticals Ireland Ltd.	Dublin, Ireland	Biopharmaceutical,Medicine	Patent: 9
46	University of Strasbourg	Alsace, France	Fields Medal,Diffusion MRI,Neuroimaging, ...[+2]	Patent: 9
47	NovMetaPharma Co., Ltd.	Kangwŏn-do, South Korea	Medicine,Drug,Antidiabetic agents, ...[+2]	Patent: 8
48	Jinan University	Guangdong Sheng, China	Chemistry,Biology,Medicine, ...[+2]	Patent: 8
49	Senju Pharmaceutical Co., Ltd.	Osaka, Japan	Drug,Glaucoma,Allergy, ...[+2]	Patent: 8
50	Shiseido Co., Ltd.	Tokyo, Japan	Cosmetics,Elixir,Personal Care Product, ...[+2]	Patent: 8
51	Huazhong Agricultural University	Hubei Sheng, China	Agronomy,Basic science,Agricultural science, ...[+2]	Patent: 8
52	University of Nebraska	Nebraska, United States		Patent: 8
53	UAB Research Foundation	Alabama, United States	Biotechnology,Agriculture,Fishery, ...[+2]	Patent: 8
54	Eisai R&D Management Co., Ltd.	Tokyo, Japan	Biotechnology,Agriculture,Fishery, ...[+2]	Patent: 7
55	Eolas Therapeutics, Inc.	California, United States	Addiction,Pharmacy and Therapeutics,Nicotine, ...[+2]	Patent: 7
56	3-D Matrix, Inc.	Massachusetts, United States	Health care,Self-assembling peptide,Wound healing, ...[+2]	Patent: 7
57	Neuren Pharmaceuticals Ltd.	Victoria, Australia	Pharmacy and Therapeutics,Neurodegeneration,Medicine, ...[+2]	Patent: 7
58	Research Triangle Institute	North Carolina, United States	Education curriculum,International development,Medicine, ...[+2]	Patent: 7
59	Intervet International BV	Noord-Brabant, Netherlands	Fertility management,Medicine,Feed additive	Patent: 7
60	Kyushu University	Fukuoka, Japan	Cultural studies,Knowledge management,Public university, ...[+2]	Patent: 7
61	Hybio Pharmaceutical Co.. Ltd.	Guangdong Sheng, China	Drug,Health care,Gastrointestinal cancer, ...[+2]	Patent: 7
62	Sandoz AG	Switzerland	Botanical drug,Herb	Patent: 6
63	Nestlé SA	Vaud, Switzerland	Ice cream,Nutrition,Cosmetics, ...[+2]	Patent: 6
64	Shanghai Institute of Materia Medica Chinese Academy of Sciences	Shanghai Shi, China	Tocilizumab,Rituximab,Toll-like receptor, ...[+2]	Patent: 6
65	AbbVie, Inc.	Illinois, United States	Health care,Medicine,Biopharmaceutical, ...[+2]	Patent: 6
66	AFFiRiS AG	Niederösterreich, Austria	Medicine,Health care,Peptide, ...[+2]	Patent: 6
67	Kyoto University	Kyoto, Japan	Gauss,Stem cell,Chemistry, ...[+2]	Patent: 6
68	Unilever IP Holdings BV	Netherlands		Patent: 6
69	University of Stellenbosch	South Africa	Academic community,Atmosphere,Knee implant, ...[+2]	Patent: 6
70	Otsuka Pharmaceutical Factory, Inc.	Tokushima, Japan	Parenteral nutrition,Human nutrition,Drug, ...[+2]	Patent: 6
71	Artelo Biosciences, Inc.	California, United States	Endocannabinoid system,Biology,Biomedicine, ...[+2]	Patent: 6
72	Nestec SA	Vaud, Switzerland	Enzyme,Nutrition,Food industry, ...[+1]	Patent: 6
73	API Corp.	Fukuoka, Japan	Medicine,Pharmaceutical formulation,Fine chemical, ...[+1]	Patent: 5
74	MetGen Oy	Western Finland, Finland	Enzyme,Amylase,Multicopper oxidase, ...[+2]	Patent: 5
75	Asahi Breweries Ltd.	Tokyo, Japan	Microbrewery,Soft drink,Brewing, ...[+2]	Patent: 5
76	Dalian University of Technology	Liaoning Sheng, China	Revocation,Materials science,Chemistry, ...[+2]	Patent: 5
77	Tianjin University	Guangdong Sheng, China	Radio-frequency identification,Coronavirus disease 2019 (COVID-19),Pinyin, ...[+2]	Patent: 5
78	Meiji Co., Ltd.	Tokyo, Japan	Food industry,Snack foods,Hard candy, ...[+2]	Patent: 5
79	Uniwersytet Medyczny w Bialymstoku	PD, PL	Bioinformatics,Medicine,Internal medicine, ...[+2]	Patent: 5
80	Yangzhou University	Jiangsu Sheng, China	Pinyin,Biology,Chemistry, ...[+2]	Patent: 5
81	Industry Foundation of Chonnam National University	South Korea	Asset management,Impact investing,Social Welfare	Patent: 5
82	Unilever NV	Zuid-Holland, Netherlands	COLA (software architecture),Soft drink,Deodorant, ...[+2]	Patent: 5
83	CJ CheilJedang Corp.	South Korea	Sugar,Food processing,Food industry, ...[+2]	Patent: 5
84	Guizhou University	Guizhou Sheng, China	Pinyin,Chemistry,Biology, ...[+2]	Patent: 5
85	Calysta, Inc.	California, United States	Petroleum industry,Fish meal,Synthetic Genes, ...[+2]	Patent: 5
86	Sun Pharmaceutical Industries Ltd.	Maharashtra, India	Inhaler,Drug,Medicine, ...[+2]	Patent: 5
87	Zhejiang University	Zhejiang Sheng, China	Pinyin,Educational institution,Cancer immunotherapy, ...[+2]	Patent: 5
88	Kikkoman Corp.	Chiba, Japan	Seasoning,Food industry,Hyaluronic acid, ...[+2]	Patent: 5
89	Mars, Inc.	Virginia, United States	Food products,Fast-moving consumer goods,Food industry, ...[+2]	Patent: 4
90	Research Institute of Innovative Technology for the Earth	Kyoto, Japan		Patent: 4
91	Fluoptics SAS	Rhône-Alpes, France	Medical imaging,Optical imaging,Health care, ...[+2]	Patent: 4
92	Takeuchi Co. Ltd.	Japan	Automation,Manufacturing engineering,Industrial engineering, ...[+2]	Patent: 4
93	Toshiba Chemical Corp.	Saitama, Japan	Electronics,Chemical engineering	Patent: 4
94	Guandong Institute of Microbiology	Guangdong Sheng, China	Microbiology	Patent: 4
95	Kyocera Corp.	Kyoto, Japan	Semiconductor,Electronics,Telecommunications, ...[+2]	Patent: 4
96	Multi & Relational System Co., Ltd.	Niigata, Japan	Web development	Patent: 4
97	Ocean University of China	Fujian Sheng, China	Fishery,Pinyin,Social science, ...[+2]	Patent: 4
98	GlaxoSmithKline Biologicals SA	Belgium	Medicine,Rubella,Hepatitis, ...[+2]	Patent: 4
99	Yafei Shanghai Biomedical Technology Co. , Ltd.	Shanghai Shi, China	Biomedical technology	Patent: 4
100	Shanghai University	Shanghai Shi, China	Pinyin,Materials science,Computer science, ...[+2]	Patent: 4