Top 100 Fast-growings companies in Proline by Most Patent Filing In 5 Years in the world in 2019 – Discovery

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The Proline top 100 is Discovery PatSnap’ annual ranking of the top 100 Most Patent Filing In 5 Years Proline Fast-growings in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2019, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated NH₂⁺ form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO⁻ form under biological conditions), and a side chain pyrrolidine, classifying it as a nonpolar (at physiological pH), aliphatic amino acid. It is non-essential in humans, meaning the body can synthesize it from the non-essential amino acid L-glutamate. It is encoded by all the codons starting CC (CCU, CCC, CCA, and CCG).

1	Koninklijke DSM NV	Netherlands	Animal nutrition,Health care,Biology, ...[+2]	Patent: 51
2	Glaxo Group Ltd.	Hounslow, United Kingdom	Food products,Medicine,Health care	Patent: 30
3	Jiangnan University	Jiangsu Sheng, China	Pinyin,Chemistry,Biochemistry, ...[+2]	Patent: 26
4	XL-protein GmbH	Bayern, Germany	Medicine,Biopharmaceutical,Drug development, ...[+2]	Patent: 22
5	DuPont Nutrition Biosciences ApS	Hovedstaden, Denmark	Food science,Medicine,Health care, ...[+2]	Patent: 21
6	Guangzhou Bosma Optoelectronic Technology Co. Ltd.	Guangdong Sheng, China	Computer hardware,Electronics,Semiconductor, ...[+1]	Patent: 20
7	Daiichi Sankyo Co., Ltd.	New Jersey, Japan	Clinical trial,Cardiovascular agent,Drug, ...[+2]	Patent: 18
8	Amgen, Inc.	California, United States	Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER, ...[+2]	Patent: 18
9	Société D'Etudes Dermatologiques SASU	Île-de-France, France	Colourant,Active ingredient,Cosmetics, ...[+2]	Patent: 17
10	BONAC Corp.	Fukuoka, Japan	Nucleic acid,Medicine,Chemical engineering, ...[+2]	Patent: 16
11	Technische Universität München	Bayern, Germany	Entrepreneurial spirit,Nutrition,Biological membrane, ...[+2]	Patent: 16
12	The a2 Milk Co. Ltd.	Auckland, New Zealand	Infant formula,Food industry,Medicine, ...[+2]	Patent: 16
13	Suntory Beverage & Food Ltd.	Tokyo, Japan	Mineral water,Ethanol,Food industry, ...[+2]	Patent: 16
14	Sundory Co. Ltd.	Japan		Patent: 16
15	STARTUP Nuritas Ltd.	Dublin, Ireland	Artificial intelligence,Data mining,Peptide, ...[+2]	Patent: 15
16	Oxford University Innovation Ltd.	Oxfordshire, United Kingdom	Technology transfer,Angel investor,Ecosystem, ...[+2]	Patent: 15
17	Osaka University	Osaka, Japan	Public university,Knowledge management,Chemistry, ...[+2]	Patent: 15
18	Ajinomoto Co., Inc.	Tokyo, Japan	Seasoning,Amino acid,Food processing, ...[+2]	Patent: 15
19	Boehringer Ingelheim Animal Health USA, Inc.	United States	Medicine,Beta cell,Classical swine fever, ...[+2]	Patent: 13
20	The Institute of Genetics & Developmental Biology	Beijing Shi, China		Patent: 13
21	Hanmi Pharmaceutical Co., Ltd.	South Korea	Medicine,Health care,Drug development, ...[+2]	Patent: 13
22	Reata Pharmaceuticals, Inc.	Texas, United States	Inflammation,Medicine,Biopharmaceutical, ...[+2]	Patent: 13
23	JCR Pharmaceuticals Co., Ltd.	Hokkaido, Japan	Raw material,Drug,Medicine, ...[+2]	Patent: 12
24	Amano Enzyme, Inc.	Nagano, Japan	Enzyme,Drug,Chemical engineering, ...[+2]	Patent: 11
25	Enanta Pharmaceuticals, Inc.	Massachusetts, United States	Medicine,Health care,Protease, ...[+2]	Patent: 11
26	Excivion Ltd.	Massachusetts, United States	Biotechnology,Bionics,Blood cell, ...[+2]	Patent: 11
27	University of Tokyo	Tokyo, Japan	Biology,Chemistry,Biochemistry, ...[+2]	Patent: 11
28	F. Hoffmann-La Roche Ltd.	Switzerland	Medicine,Health care,Drug, ...[+2]	Patent: 11
29	AmtixBio Co., Ltd.			Patent: 10
30	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	Patent: 10
31	Jiangsu Hengrui Pharmaceuticals Co., Ltd.	Jiangsu Sheng, China	Drug,Health care,Antineoplastic Drugs, ...[+2]	Patent: 10
32	Kobe University	Kyoto, Japan	Biochemistry,Cancer research,Aptamer, ...[+2]	Patent: 10
33	Geo-Poland Sp zoo	Greater Poland, Poland		Patent: 10
34	Bristol Myers Co.	New York, United States	Botanical drug,Herb	Patent: 10
35	Fuji Oil Holdings, Inc.	Osaka, Japan	Soy protein,Food processing,Textured vegetable protein, ...[+2]	Patent: 10
36	Fuji Oil Co. Ltd. (Osaka)	Osaka, Japan	Agriculture,Fertilizer,Animal fat, ...[+2]	Patent: 10
37	Institut National de la Santé et de la Recherche Médicale	Île-de-France, France	Public health,Genomics,Antisense therapy, ...[+2]	Patent: 10
38	Hybio Pharmaceutical Co.. Ltd.	Guangdong Sheng, China	Drug,Health care,Gastrointestinal cancer, ...[+2]	Patent: 10
39	STARTUP INSERM Limoges		E-commerce	Patent: 10
40	Virometix AG	Zürich, Switzerland	Medicine,Health care,Cancer vaccine, ...[+2]	Patent: 10
41	NovMetaPharma Co., Ltd.	Kangwŏn-do, South Korea	Medicine,Drug,Antidiabetic agents, ...[+2]	Patent: 9
42	University of Zurich	Zürich, Switzerland	Structural biology,Neuroscience,Public sector, ...[+2]	Patent: 9
43	Société des Produits Nestlé SA	Vaud, Switzerland	Food industry	Patent: 9
44	KWS SAAT SE & Co. KGaA	Germany	Rapeseed,Agriculture,Hybrid seed, ...[+2]	Patent: 9
45	Merz Pharma GmbH & Co. KGaA	Sachsen, Germany	Psychiatry,Neurology,Breast implant, ...[+2]	Patent: 9
46	Unilever NV	Zuid-Holland, Netherlands	COLA (software architecture),Soft drink,Deodorant, ...[+2]	Patent: 9
47	Octapharma AG	Schwyz, Switzerland	Medicine,Health care,Collective responsibility, ...[+2]	Patent: 9
48	Jazz Pharmaceuticals Ireland Ltd.	Dublin, Ireland	Biopharmaceutical,Medicine	Patent: 9
49	University of Strasbourg	Alsace, France	Fields Medal,Diffusion MRI,Neuroimaging, ...[+2]	Patent: 9
50	Sandoz AG	Switzerland	Botanical drug,Herb	Patent: 8
51	MetGen Oy	Western Finland, Finland	Enzyme,Amylase,Multicopper oxidase, ...[+2]	Patent: 8
52	Uniwersytet Medyczny w Bialymstoku	PD, PL	Bioinformatics,Medicine,Internal medicine, ...[+2]	Patent: 8
53	Senju Pharmaceutical Co., Ltd.	Osaka, Japan	Drug,Glaucoma,Allergy, ...[+2]	Patent: 8
54	Shiseido Co., Ltd.	Tokyo, Japan	Cosmetics,Elixir,Personal Care Product, ...[+2]	Patent: 8
55	Huazhong Agricultural University	Hubei Sheng, China	Agronomy,Basic science,Agricultural science, ...[+2]	Patent: 8
56	Kao Corp.	Tokyo, Japan	Cosmetics,Health care,Hair conditioner, ...[+2]	Patent: 8
57	University of Nebraska	Nebraska, United States		Patent: 8
58	UAB Research Foundation	Alabama, United States	Biotechnology,Agriculture,Fishery, ...[+2]	Patent: 8
59	Eisai R&D Management Co., Ltd.	Tokyo, Japan	Biotechnology,Agriculture,Fishery, ...[+2]	Patent: 7
60	3-D Matrix, Inc.	Massachusetts, United States	Health care,Self-assembling peptide,Wound healing, ...[+2]	Patent: 7
61	Unilever IP Holdings BV	Netherlands		Patent: 7
62	Research Triangle Institute	North Carolina, United States	Education curriculum,International development,Medicine, ...[+2]	Patent: 7
63	Intervet International BV	Noord-Brabant, Netherlands	Fertility management,Medicine,Feed additive	Patent: 7
64	Kyushu University	Fukuoka, Japan	Cultural studies,Knowledge management,Public university, ...[+2]	Patent: 7
65	Artelo Biosciences, Inc.	California, United States	Endocannabinoid system,Biology,Biomedicine, ...[+2]	Patent: 7
66	Shanghai Institute of Materia Medica Chinese Academy of Sciences	Shanghai Shi, China	Tocilizumab,Rituximab,Toll-like receptor, ...[+2]	Patent: 6
67	Tianjin University	Guangdong Sheng, China	Radio-frequency identification,Coronavirus disease 2019 (COVID-19),Pinyin, ...[+2]	Patent: 6
68	Norwegian University of Science & Technology	Sør-Trøndelag, Norway	Endoscopy,Endoscope,Capsule Endoscopes, ...[+2]	Patent: 6
69	Otsuka Pharmaceutical Factory, Inc.	Tokushima, Japan	Parenteral nutrition,Human nutrition,Drug, ...[+2]	Patent: 6
70	Conopco, Inc.	NJ, US	Lotion	Patent: 6
71	Tianjin University of Science & Technology	Guangdong Sheng, China	Chemistry,Biochemistry,Chromatography, ...[+2]	Patent: 6
72	API Corp.	Fukuoka, Japan	Medicine,Pharmaceutical formulation,Fine chemical, ...[+1]	Patent: 5
73	Nestlé SA	Vaud, Switzerland	Ice cream,Nutrition,Cosmetics, ...[+2]	Patent: 5
74	Takeuchi Co. Ltd.	Japan	Automation,Manufacturing engineering,Industrial engineering, ...[+2]	Patent: 5
75	Saitama Medical University	Japan		Patent: 5
76	Guandong Institute of Microbiology	Guangdong Sheng, China	Microbiology	Patent: 5
77	AFFiRiS AG	Niederösterreich, Austria	Medicine,Health care,Peptide, ...[+2]	Patent: 5
78	Ocean University of China	Fujian Sheng, China	Fishery,Pinyin,Social science, ...[+2]	Patent: 5
79	Changzhou University	Jiangsu Sheng, China		Patent: 5
80	Kyoto University	Kyoto, Japan	Gauss,Stem cell,Chemistry, ...[+2]	Patent: 5
81	University of Stellenbosch	South Africa	Academic community,Atmosphere,Knee implant, ...[+2]	Patent: 5
82	East China University of Science & Technology	Shanghai Shi, China	Syngas,Biomass,Biofuel, ...[+2]	Patent: 5
83	Zhejiang University of Technology	Zhejiang Sheng, China	Pinyin,Mainland China,Chemistry, ...[+2]	Patent: 5
84	Guizhou University	Guizhou Sheng, China	Pinyin,Chemistry,Biology, ...[+2]	Patent: 5
85	Calysta, Inc.	California, United States	Petroleum industry,Fish meal,Synthetic Genes, ...[+2]	Patent: 5
86	Taiyuan University of Technology	Taiwan Province, China	Pinyin,Materials science,Chemistry, ...[+2]	Patent: 5
87	Sun Pharmaceutical Industries Ltd.	Maharashtra, India	Inhaler,Drug,Medicine, ...[+2]	Patent: 5
88	Nestec SA	Vaud, Switzerland	Enzyme,Nutrition,Food industry, ...[+1]	Patent: 5
89	China Pharmaceutical University	Jiangsu Sheng, China	Pharmaceutical sciences,Chemistry,Retinitis, ...[+2]	Patent: 5
90	Fluoptics SAS	Rhône-Alpes, France	Medical imaging,Optical imaging,Health care, ...[+2]	Patent: 4
91	Idemitsu Kosan Co., Ltd.	Tokyo, Japan	Petrochemical,Lubricant,Petroleum, ...[+2]	Patent: 4
92	Toshiba Chemical Corp.	Saitama, Japan	Electronics,Chemical engineering	Patent: 4
93	Dalian University of Technology	Liaoning Sheng, China	Revocation,Materials science,Chemistry, ...[+2]	Patent: 4
94	Eolas Therapeutics, Inc.	California, United States	Addiction,Pharmacy and Therapeutics,Nicotine, ...[+2]	Patent: 4
95	Kyocera Corp.	Kyoto, Japan	Semiconductor,Electronics,Telecommunications, ...[+2]	Patent: 4
96	Meiji Co., Ltd.	Tokyo, Japan	Food industry,Snack foods,Hard candy, ...[+2]	Patent: 4
97	Uniwersytet Przyrodniczo-Humanistyczny w Siedlcach	Mazowieckie, Poland	Graduate degree,The Internet,Simulation, ...[+2]	Patent: 4
98	Yafei Shanghai Biomedical Technology Co. , Ltd.	Shanghai Shi, China	Biomedical technology	Patent: 4
99	Yangzhou University	Jiangsu Sheng, China	Pinyin,Biology,Chemistry, ...[+2]	Patent: 4
100	Toray Industries, Inc.	Tokyo, Japan	Fiber,Textile,Textile (markup language), ...[+2]	Patent: 4