Top 100 Key Players companies in Calcium channel blocker by Highest Patent Value in the world in 2019 – Discovery

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The Calcium channel blocker top 100 is Discovery PatSnap’ annual ranking of the top 100 Highest Patent Value Calcium channel blocker Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2019, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

Calcium channel blockers (CCB), calcium channel antagonists or calcium antagonists are a group of medications that disrupt the movement of calcium (Ca²⁺) through calcium channels. Calcium channel blockers are used as antihypertensive drugs, i.e., as medications to decrease blood pressure in patients with hypertension. CCBs are particularly effective against large vessel stiffness, one of the common causes of elevated systolic blood pressure in elderly patients. Calcium channel blockers are also frequently used to alter heart rate (especially from atrial fibrillation), to prevent peripheral and cerebral vasospasm, and to reduce chest pain caused by angina pectoris.

1	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	Avg patent value: 10.28 M
2	Bristol Myers Co.	New York, United States	Botanical drug,Herb	Avg patent value: 10.28 M
3	United Therapeutics Corp.	United States	Medicine,Pharmacy and Therapeutics,Biotechnology, ...[+2]	Avg patent value: 9.02 M
4	Taro Pharmaceuticals, Inc.	Ontario, Canada	Medicine,Generic drug,Ifosfamide, ...[+2]	Avg patent value: 6.63 M
5	Zalicus Pharmaceuticals Ltd.	British Columbia, Canada	Medicine,Biopharmaceutical,Drug, ...[+2]	Avg patent value: 6.63 M
6	Mylan Specialty LP	New Jersey, United States	Epinephrine,Medicine,Allergy drugs, ...[+2]	Avg patent value: 6.43 M
7	Critical Care Diagnostics, Inc.	California, United States	Medicine,Health care,Cardiac marker, ...[+2]	Avg patent value: 6.01 M
8	BIAL-Portela & Cia SA	Porto, Portugal	Eslicarbazepine acetate,Medicine,Health care, ...[+2]	Avg patent value: 6.00 M
9	Praxis Precision Medicines, Inc.	Massachusetts, United States	Medicine,Health care,Neurodevelopmental disorder, ...[+2]	Avg patent value: 5.90 M
10	Milestone Pharmaceuticals, Inc.	Quebec, Canada	Medicine,Health care,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 5.31 M
11	Jagotec AG	Schwyz, Switzerland		Avg patent value: 5.08 M
12	Nissan Chemical Corp.	Tokyo, Japan	Pesticide,Meiji period,Fertilizer, ...[+2]	Avg patent value: 4.91 M
13	BASF SE	Rheinland-Pfalz, Germany	Agriculture,Petrochemical,Chemical engineering, ...[+2]	Avg patent value: 4.65 M
14	Toray Industries, Inc.	Tokyo, Japan	Fiber,Textile,Textile (markup language), ...[+2]	Avg patent value: 4.45 M
15	Sanofi-Aventis Ltd.	United Kingdom	Medicine,Thrombosis,Metabolic disorder, ...[+2]	Avg patent value: 4.45 M
16	Omeros Corp.	Washington, United States	Medicine,Health care,Central nervous system, ...[+2]	Avg patent value: 4.38 M
17	Merck Patent GmbH	Hessen, Germany		Avg patent value: 4.11 M
18	In Therapeutics	South Korea		Avg patent value: 3.93 M
19	BIT Pharma GmbH	Austria		Avg patent value: 3.91 M
20	Boehringer Ingelheim Pharma GmbH	Austria	Proton-pump inhibitor,Antacid,Bevacizumab, ...[+2]	Avg patent value: 3.89 M
21	Daewoong Pharmaceutical Co., Ltd.	South Korea	Global health,Medicine,Over-the-counter, ...[+2]	Avg patent value: 3.64 M
22	Boehringer Ingelheim Pharmaceuticals, Inc.	Connecticut, United States	Central nervous system,Medicine,Drug, ...[+2]	Avg patent value: 3.41 M
23	Idorsia Ltd.	Basel-Landschaft, Switzerland	Medicine,Health care,Cerebral vasospasm, ...[+2]	Avg patent value: 2.91 M
24	Idorsia Pharmaceuticals Ltd.	Switzerland	Herb,Botanical drug	Avg patent value: 2.91 M
25	Hua Medicine Ltd.	Shanghai Shi, China	Biology,Medicine,Health care, ...[+2]	Avg patent value: 2.86 M
26	AbbVie Bahamas Ltd.	The Bahamas		Avg patent value: 2.39 M
27	Daiichi Sankyo Co., Ltd.	New Jersey, Japan	Clinical trial,Cardiovascular agent,Drug, ...[+2]	Avg patent value: 2.36 M
28	DAE HWA PHARM Co., Ltd.	South Korea	Medicine,Drug,Anti-inflammatory, ...[+2]	Avg patent value: 2.35 M
29	Les Laboratoires Servier SAS	Île-de-France, France	Heart failure,Medicine,Clinical trial, ...[+2]	Avg patent value: 2.28 M
30	Purdue Pharma LP	Connecticut, United States	Opioid,Medicine,Opioid epidemic, ...[+2]	Avg patent value: 2.20 M
31	Purdue Pharma, Inc.	Connecticut, United States	Health care,Healthcare system,Educational program, ...[+1]	Avg patent value: 2.20 M
32	RaQualia Pharma, Inc.	Aichi, Japan	Drug discovery,Gastrointestinal agent,Drug development, ...[+2]	Avg patent value: 2.16 M
33	Nanning Fengye Pharmaceutical Co Ltd	China		Avg patent value: 1.91 M
34	Algenis SpA	Chile	Clinical trial,Sodium channel blocker,Molecule, ...[+2]	Avg patent value: 1.71 M
35	Parion Sciences, Inc.	North Carolina, United States	Health care,Nebulizer,Mucus, ...[+2]	Avg patent value: 1.60 M
36	Cardix Therapeutics LLC	United States		Avg patent value: 1.57 M
37	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	Avg patent value: 1.56 M
38	Peptides International LLC	Kentucky, United States	Peptide,Biocompatible material,Amino acid derivative, ...[+2]	Avg patent value: 1.54 M
39	Merck Sharp & Dohme Corp.	New Jersey, United States	Prescription drug,Medicine,Stroke, ...[+2]	Avg patent value: 1.52 M
40	Boryung Corp.	South Korea	Medicine,Health care,Amino acid, ...[+2]	Avg patent value: 1.46 M
41	Massachusetts General Hospital	Massachusetts, United States	Substance abuse,Hospitality industry,Health care, ...[+2]	Avg patent value: 1.44 M
42	The General Hospital Corp.	Massachusetts, United States	Health care,Hospitality industry,Vascular Medicine, ...[+2]	Avg patent value: 1.44 M
43	EA Pharma Co., Ltd.	Tokyo, Japan	Gastrointestinal agent,Ulcerative colitis,Secondary hyperparathyroidism, ...[+2]	Avg patent value: 1.38 M
44	Sankyo Co., Ltd.	Tokyo, Japan	Ball bearing,Manufacturing engineering,Glatiramer acetate, ...[+2]	Avg patent value: 1.16 M
45	Janssen Pharmaceutica NV	Antwerpen, Belgium	Product design,Neuroscience,Health care, ...[+2]	Avg patent value: 1.13 M
46	Novartis Pharmaceuticals Corp.	New Jersey, United States	Medicine,Prescription drug,Cardiovascular agent, ...[+2]	Avg patent value: 990,000
47	Novartis AG	Basel-Stadt, Switzerland	Dosage form,Health care,Medicine, ...[+2]	Avg patent value: 959,000
48	Johnson & Johnson	New Jersey, United States	Health care,Medical equipment,Risperidone, ...[+2]	Avg patent value: 940,000
49	AbbVie, Inc.	Illinois, United States	Health care,Medicine,Biopharmaceutical, ...[+2]	Avg patent value: 904,000
50	Boston Foundation for Sight	Massachusetts, United States	Cornea,Sight,Biomedicine, ...[+2]	Avg patent value: 770,000
51	L'Oréal SA	Île-de-France, France	Cosmetics,Urban decay,Hair conditioner, ...[+2]	Avg patent value: 740,000
52	Bionomics Ltd.	South Australia, Australia	Bionomics,Health care,Medicine, ...[+2]	Avg patent value: 660,000
53	Landsteiner Scientific SA de CV	Maine, United States	Medicine,Tanezumab,Pregabalin, ...[+2]	Avg patent value: 620,000
54	Novartis Farma	Russia		Avg patent value: 545,000
55	Edge Therapeutics, Inc.	New Jersey, United States	Clinical trial,Health care,Biotechnology, ...[+2]	Avg patent value: 500,000
56	Euro-Celtique SA	Luxembourg, Luxembourg		Avg patent value: 420,000
57	Representaciones e Investigaciones Médicas SA de CV	DF, MX	Medicine	Avg patent value: 410,000
58	Nektar Therapeutics	California, United States	Biopharmaceutical,Chemical engineering,Health care, ...[+2]	Avg patent value: 400,000
59	BioMed Valley Discoveries, Inc.	Missouri, United States	Inflammation,Health care,Oncology drugs, ...[+2]	Avg patent value: 400,000
60	Nektar Therapeutics AL Corp.	Alabama, United States	Ethylene glycol,Ethylene,Chemical engineering	Avg patent value: 400,000
61	Purple Biotech Ltd.	Tel Aviv, Israel	Type I hypersensitivity,Medicine,Cancer immunotherapy, ...[+2]	Avg patent value: 330,000
62	Kitov Pharmaceuticals Ltd.	Israel	Drug,Medical equipment,Medicine	Avg patent value: 330,000
63	Asahi Kasei Corp.	Tokyo, Japan	Chemical engineering,Petrochemical,Fertilizer, ...[+2]	Avg patent value: 260,000
64	Asahi Kasei Pharma Corp.	Tokyo, Japan	Diagnostic Reagent,Transdermal patch,Medicine, ...[+2]	Avg patent value: 260,000
65	USV Pvt Ltd.	Maharashtra, India	Peptide,Health care,Insulin aspart, ...[+2]	Avg patent value: 240,000
66	Indicus Pharma LLC	North Carolina, United States	Medicine	Avg patent value: 240,000
67	Abbott GmbH (Germany)	Hessen, Germany	Health care,Medicine	Avg patent value: 180,000
68	Acorda Therapeutics, Inc.	New York, United States	Software development,Health care,Inhaler, ...[+2]	Avg patent value: 167,000
69	NTG Nordic Transport Group A/S	Hovedstaden, Denmark	Medicine,Health care,Ion channel, ...[+2]	Avg patent value: 146,800
70	Bayer Schering Pharma AG	Berlin, Germany	Medicine,Botanical drug,Herb	Avg patent value: 140,000
71	Grünenthal GmbH	Nordrhein-Westfalen, Germany	Medicine,Health care,Clinical trial, ...[+2]	Avg patent value: 130,695
72	Wockhardt Ltd.	Maharashtra, India	Pharmacy,Insulin,Biopharmaceutical, ...[+2]	Avg patent value: 120,000
73	Alvogen Korea Co., Ltd.	Seoul, South Korea	Candesartan,Pharmacy,Medicine, ...[+2]	Avg patent value: 120,000
74	Therapeutics, Inc.	California, United States	Drug development,Medicine,Health care, ...[+1]	Avg patent value: 120,000
75	Neuromed Pharmaceuticals Ltd.	British Columbia, Canada	Health care	Avg patent value: 120,000
76	LG H&H Co., Ltd.	South Korea	Health care,Physical fitness,Fabric softener, ...[+2]	Avg patent value: 110,000
77	Hanmi Science Co., Ltd.	South Korea	Clinical trial,Medicine,Drug repositioning, ...[+2]	Avg patent value: 110,000
78	NitroMed, Inc.	Massachusetts, United States	Medicine,Health care,Confirmatory trial, ...[+2]	Avg patent value: 100,000
79	Synergistic Therapeutics LLC	FL, US		Avg patent value: 99,333
80	Jiangsu Simcere Pharmaceutical Co., Ltd.	Jiangsu Sheng, China	Medicine	Avg patent value: 96,500
81	Jiangsu Wuzhong Medicine Group Co., Ltd.	JS, CN	Pharmacy,Drug,Medicine	Avg patent value: 95,000
82	Jiangsu Wuzhong Pharmaceutical Group Co., Ltd. Suzhou Pharmaceutical Factory			Avg patent value: 95,000
83	TSH Biopharm Corp., Ltd.	Taiwan Province, China	Gastroenterology,Health care,Medicine, ...[+2]	Avg patent value: 93,000
84	STARTUP Nocion Therapeutics, Inc.	Massachusetts, United States	Intracellular sodium,Health care,Inflammation, ...[+1]	Avg patent value: 77,111
85	Nanjing Chia Tai Tianqing Pharmaceutical Co., Ltd.	Jiangsu Sheng, China		Avg patent value: 77,000
86	Gilead Sciences, Inc.	California, United States	Medicine,Health care,Biopharmaceutical, ...[+2]	Avg patent value: 65,000
87	SignPath Pharma, Inc.	Pennsylvania, United States	Pharmacy and Therapeutics,Curcumin,Curcuminoid, ...[+2]	Avg patent value: 64,000
88	Intro Bio Pharma Co., Ltd.	South Korea	Biotechnology	Avg patent value: 63,000
89	Shenzhen Salubris Pharmaceuticals Co., Ltd.	Guangdong Sheng, China	Medicine,Cefaclor,Antithrombotic, ...[+2]	Avg patent value: 62,000
90	Shandong Salubris Pharmaceuticals Co., Ltd.	China		Avg patent value: 62,000
91	Devenish Nutrition Ltd.	Minnesota, United States	Animal nutrition,Nutrition,Food processing, ...[+2]	Avg patent value: 58,000
92	Noscira SA	Madrid, Spain	Biopharmaceutical,Rivastigmine,Donepezil, ...[+2]	Avg patent value: 58,000
93	Hangzhou Weibolai Biological Technology Co., Ltd.	Zhejiang Sheng, China		Avg patent value: 53,000
94	BGI Shenzhen Co., Ltd.	Guangdong Sheng, China	Internet of Things,Biotechnology,Genomics	Avg patent value: 49,000
95	NovaMedica LLC	Russia	Ophthalmology,Gastroenterology,Health care, ...[+2]	Avg patent value: 42,000
96	Xian Hanfeng Pharmaceutical Co. Ltd.	China		Avg patent value: 36,000
97	Etypharm	France	Health care,Hospitality industry	Avg patent value: 35,000
98	AstraZeneca Plc	Cambridgeshire, United Kingdom	Medicine,Health care,Side effect, ...[+2]	Avg patent value: 32,000
99	AstraZeneca UK Ltd.	Cambridgeshire, United Kingdom	Gastrointestinal infections,Medicine,Simvastatin, ...[+2]	Avg patent value: 32,000
100	American Regent, Inc.	New York, United States	Drug,Contract Manufacturing,Medicine, ...[+2]	Avg patent value: 31,000