Top 100 Key Players companies in Calcium channel blocker by Most Patent Citation in the world in 2019 – Discovery

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The Calcium channel blocker top 100 is Discovery PatSnap’ annual ranking of the top 100 Most Patent Citation Calcium channel blocker Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2019, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

Calcium channel blockers (CCB), calcium channel antagonists or calcium antagonists are a group of medications that disrupt the movement of calcium (Ca²⁺) through calcium channels. Calcium channel blockers are used as antihypertensive drugs, i.e., as medications to decrease blood pressure in patients with hypertension. CCBs are particularly effective against large vessel stiffness, one of the common causes of elevated systolic blood pressure in elderly patients. Calcium channel blockers are also frequently used to alter heart rate (especially from atrial fibrillation), to prevent peripheral and cerebral vasospasm, and to reduce chest pain caused by angina pectoris.

1	Parion Sciences, Inc.	North Carolina, United States	Health care,Nebulizer,Mucus, ...[+2]	patent citation: 3,454
2	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	patent citation: 2,909
3	Zalicus Pharmaceuticals Ltd.	British Columbia, Canada	Medicine,Biopharmaceutical,Drug, ...[+2]	patent citation: 1,419
4	Isotechnika, Inc.	Alberta, Canada	Medicine,Breathalyzer,Autoimmune disease, ...[+2]	patent citation: 1,160
5	Merck Sharp & Dohme Corp.	New Jersey, United States	Prescription drug,Medicine,Stroke, ...[+2]	patent citation: 656
6	Purdue Pharma LP	Connecticut, United States	Opioid,Medicine,Opioid epidemic, ...[+2]	patent citation: 615
7	Purdue Pharma, Inc.	Connecticut, United States	Health care,Healthcare system,Educational program, ...[+1]	patent citation: 615
8	NTG Nordic Transport Group A/S	Hovedstaden, Denmark	Medicine,Health care,Ion channel, ...[+2]	patent citation: 332
9	Euro-Celtique SA	Luxembourg, Luxembourg		patent citation: 232
10	EKR Therapeutics, Inc.	New Jersey, United States	Health care,Pharmacy and Therapeutics,Stomatitis, ...[+2]	patent citation: 223
11	Neuromed Pharmaceuticals Ltd.	British Columbia, Canada	Health care	patent citation: 220
12	Smithkline Beckman Corp	Pennsylvania, United States	Biotechnology,Medicine	patent citation: 207
13	Novartis AG	Basel-Stadt, Switzerland	Dosage form,Health care,Medicine, ...[+2]	patent citation: 199
14	Kyowa Kirin Ltd.	Scottish Borders, United Kingdom	Medicine	patent citation: 186
15	HANALL BIOPHARMA Co., Ltd.	South Korea	Physical fitness,Drug,Erectile dysfunction, ...[+2]	patent citation: 183
16	Boehringer Ingelheim Pharmaceuticals, Inc.	Connecticut, United States	Central nervous system,Medicine,Drug, ...[+2]	patent citation: 179
17	Novartis Pharma GmbH	WI, AT	Pharmacy,Drug,Medicine	patent citation: 158
18	NitroMed, Inc.	Massachusetts, United States	Medicine,Health care,Confirmatory trial, ...[+2]	patent citation: 157
19	Daiichi Sankyo Co., Ltd.	New Jersey, Japan	Clinical trial,Cardiovascular agent,Drug, ...[+2]	patent citation: 142
20	Glaxo Group Ltd.	Hounslow, United Kingdom	Food products,Medicine,Health care	patent citation: 141
21	RaQualia Pharma, Inc.	Aichi, Japan	Drug discovery,Gastrointestinal agent,Drug development, ...[+2]	patent citation: 140
22	E.I. du Pont de Nemours & Co.	Delaware, United States	Agriculture,Materials science,Electronics, ...[+2]	patent citation: 126
23	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	patent citation: 118
24	AstraZeneca Plc	Cambridgeshire, United Kingdom	Medicine,Health care,Side effect, ...[+2]	patent citation: 117
25	AstraZeneca UK Ltd.	Cambridgeshire, United Kingdom	Gastrointestinal infections,Medicine,Simvastatin, ...[+2]	patent citation: 117
26	Elan Pharmaceuticals, LLC	Michigan, United States	Autoimmune disease,Medicine,Enzyme, ...[+2]	patent citation: 117
27	S.L.A. Pharma AG	Basel-Landschaft, Switzerland	Familial adenomatous polyposis,Health care,Gastrointestinal agent, ...[+1]	patent citation: 112
28	Novartis Pharmaceuticals Corp.	New Jersey, United States	Medicine,Prescription drug,Cardiovascular agent, ...[+2]	patent citation: 109
29	Abbott Laboratories Ltd.	United Kingdom	Medicine,Photomedicine,Drug carrier, ...[+2]	patent citation: 107
30	Sankyo Co., Ltd.	Tokyo, Japan	Ball bearing,Manufacturing engineering,Glatiramer acetate, ...[+2]	patent citation: 103
31	Synthon IP, Inc.	VA, US		patent citation: 88
32	Boston Scientific Scimed, Inc.	Minnesota, United States	Medical equipment,Health care,Cloud computing, ...[+2]	patent citation: 83
33	Janssen Pharmaceutica NV	Antwerpen, Belgium	Product design,Neuroscience,Health care, ...[+2]	patent citation: 81
34	Andrx Pharmaceuticals LLC	Virginia, United States	Scientific instrument,Drug,Medicine	patent citation: 81
35	G.D. Searle LLC	Illinois, United States		patent citation: 76
36	Boehringer Ingelheim Pharma GmbH	Austria	Proton-pump inhibitor,Antacid,Bevacizumab, ...[+2]	patent citation: 75
37	F. Hoffmann-La Roche Ltd.	Switzerland	Medicine,Health care,Drug, ...[+2]	patent citation: 74
38	Massachusetts General Hospital	Massachusetts, United States	Substance abuse,Hospitality industry,Health care, ...[+2]	patent citation: 72
39	The General Hospital Corp.	Massachusetts, United States	Health care,Hospitality industry,Vascular Medicine, ...[+2]	patent citation: 72
40	Xenon Pharmaceuticals, Inc.	British Columbia, Canada	Phenotype,Medicine,Health care, ...[+2]	patent citation: 66
41	Elan Corp. Plc	Dublin, Ireland	Botanical drug,Herb,Biotechnology, ...[+2]	patent citation: 61
42	Cellegy Pharmaceuticals, Inc.	Pennsylvania, United States	Biopharmaceutical,Vulvodynia	patent citation: 61
43	Abeille Pharmaceuticals, Inc.	New Jersey, United States	Metabolic disorder,Medicine,Oncology	patent citation: 61
44	Compellis Pharmaceuticals, Inc.	MA, US	Drug,Botanical drug,Herb	patent citation: 60
45	PDL BioPharma, Inc.	Nevada, United States	Patent portfolio,Health care,Drug discovery, ...[+2]	patent citation: 57
46	Gilead Sciences, Inc.	California, United States	Medicine,Health care,Biopharmaceutical, ...[+2]	patent citation: 50
47	Memory Pharmaceuticals Corp.	New Jersey, United States	Central nervous system,Medicine	patent citation: 46
48	Grünenthal GmbH	Nordrhein-Westfalen, Germany	Medicine,Health care,Clinical trial, ...[+2]	patent citation: 45
49	Milestone Pharmaceuticals, Inc.	Quebec, Canada	Medicine,Health care,Pharmacy and Therapeutics, ...[+2]	patent citation: 42
50	Neurex Corp.	California, United States	Biopharmaceutical,Acute care,Botanical drug, ...[+1]	patent citation: 40
51	Wockhardt Ltd.	Maharashtra, India	Pharmacy,Insulin,Biopharmaceutical, ...[+2]	patent citation: 38
52	Newron Pharmaceuticals SpA	Lombardia, Italy	Safinamide,Health care,Levodopa, ...[+2]	patent citation: 38
53	CV Therapeutics, Inc.	California, United States	Drug,Pharmacy and Therapeutics,Angina, ...[+2]	patent citation: 38
54	AbbVie, Inc.	Illinois, United States	Health care,Medicine,Biopharmaceutical, ...[+2]	patent citation: 36
55	Nicox SA	Provence-Alpes-Côte d'Azur, France	Medicine,Medical equipment,Health care, ...[+2]	patent citation: 36
56	Vertex Pharmaceuticals, Inc.	Massachusetts, United States	Health care,Medicine,Cystic fibrosis, ...[+2]	patent citation: 34
57	BIAL-Portela & Cia SA	Porto, Portugal	Eslicarbazepine acetate,Medicine,Health care, ...[+2]	patent citation: 34
58	Phoenix Biosciences, Inc.	United States		patent citation: 34
59	Matrix Laboratories BV (Belgium)	Belgium	Pharmaceutical drug,Medicine	patent citation: 34
60	Idorsia Ltd.	Basel-Landschaft, Switzerland	Medicine,Health care,Cerebral vasospasm, ...[+2]	patent citation: 32
61	Idorsia Pharmaceuticals Ltd.	Switzerland	Herb,Botanical drug	patent citation: 32
62	Jagotec AG	Schwyz, Switzerland		patent citation: 31
63	Abbott GmbH (Germany)	Hessen, Germany	Health care,Medicine	patent citation: 30
64	Pharmacia Corp.	New Jersey, United States	Botanical drug,Herb,Ophthalmology, ...[+2]	patent citation: 29
65	WEX Pharmaceuticals, Inc.	British Columbia, Canada	Medicine,Tetrodotoxin,Drug, ...[+2]	patent citation: 29
66	Afexa Life Sciences, Inc.	Alberta, Canada	Medicine,Natural Health Products,Standardization, ...[+1]	patent citation: 28
67	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	patent citation: 25
68	Bristol Myers Co.	New York, United States	Botanical drug,Herb	patent citation: 25
69	UBE Corp.	Tokyo, Japan	Synthetic rubber,Chemical engineering,Coal mining, ...[+2]	patent citation: 24
70	STARTUP SyntheX, Inc.	California, United States	Biology,Medicine,Pharmacy and Therapeutics, ...[+2]	patent citation: 24
71	Gilead Colorado, Inc.	Colorado, United States		patent citation: 24
72	L'Oréal SA	Île-de-France, France	Cosmetics,Urban decay,Hair conditioner, ...[+2]	patent citation: 23
73	Boryung Corp.	South Korea	Medicine,Health care,Amino acid, ...[+2]	patent citation: 23
74	Convergence Pharmaceuticals Ltd.	United Kingdom	Analgesic,Sodium channel blocker,Medicine, ...[+2]	patent citation: 22
75	Acorda Therapeutics, Inc.	New York, United States	Software development,Health care,Inhaler, ...[+2]	patent citation: 21
76	Artesian Therapeutics, Inc.	United States	Medicine,Pharmacy and Therapeutics	patent citation: 19
77	Bayer HealthCare AG	Nordrhein-Westfalen, Germany	Health care,Diabetes Therapy,Immunoprotein, ...[+2]	patent citation: 18
78	Bayer Healthcare LLC	New Jersey, United States	Pharmaceutical medicine,Medicine,Computed tomography, ...[+2]	patent citation: 18
79	BioMed Valley Discoveries, Inc.	Missouri, United States	Inflammation,Health care,Oncology drugs, ...[+2]	patent citation: 18
80	Merck Patent GmbH	Hessen, Germany		patent citation: 18
81	John Wyeth & Brother Ltd.	Kent, United Kingdom	Medicine,Influenza vaccine,Protein therapeutics, ...[+1]	patent citation: 18
82	Therapeutics, Inc.	California, United States	Drug development,Medicine,Health care, ...[+1]	patent citation: 16
83	Boston Foundation for Sight	Massachusetts, United States	Cornea,Sight,Biomedicine, ...[+2]	patent citation: 16
84	Edge Therapeutics, Inc.	New Jersey, United States	Clinical trial,Health care,Biotechnology, ...[+2]	patent citation: 15
85	UAB Research Foundation	Alabama, United States	Biotechnology,Agriculture,Fishery, ...[+2]	patent citation: 13
86	Shionogi & Co., Ltd.	Osaka, Japan	Health care,Antihypercholesterolemic agent,Drug, ...[+2]	patent citation: 12
87	Torrent Pharmaceuticals Ltd.	Gujarat, India	Clinical trial,Tranquilizer,Medicine, ...[+2]	patent citation: 12
88	SignPath Pharma, Inc.	Pennsylvania, United States	Pharmacy and Therapeutics,Curcumin,Curcuminoid, ...[+2]	patent citation: 12
89	American Can Co.	United States	Tin can,Packaging engineering,Microservices, ...[+1]	patent citation: 12
90	Marion Laboratories	Missouri, United States	Drug,Medical equipment,Medicine, ...[+2]	patent citation: 12
91	FX Life Sciences AG	Switzerland		patent citation: 12
92	Daewoong Pharmaceutical Co., Ltd.	South Korea	Global health,Medicine,Over-the-counter, ...[+2]	patent citation: 11
93	Bionomics Ltd.	South Australia, Australia	Bionomics,Health care,Medicine, ...[+2]	patent citation: 11
94	ARYx Therapeutics, Inc.	California, United States	Medicine,Pharmacy and Therapeutics,Typical antipsychotic, ...[+2]	patent citation: 11
95	MediProPharma, Inc.	Utah, United States	Biotechnology,Health care	patent citation: 11
96	Praxis Precision Medicines, Inc.	Massachusetts, United States	Medicine,Health care,Neurodevelopmental disorder, ...[+2]	patent citation: 10
97	MEDA Pharma GmbH & Co. KG	Hessen, Germany	Medicine,Anticonvulsant,Gabapentin, ...[+2]	patent citation: 10
98	Hyundai Pharmaceutical Co., Ltd.	South Korea	Fair trade,Medicine,Clinical trial, ...[+2]	patent citation: 9
99	Key Pharmaceuticals, Inc.	NJ, US	Drug,Pharmacy,Medicine	patent citation: 9
100	CombinatoRx, Inc.	Massachusetts, United States	Drug,Health care,Clinical trial, ...[+2]	patent citation: 9