Top 100 Key Players companies in Calprotectin by Most News Heat in the world in 2019 – Discovery

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The Calprotectin top 100 is Discovery PatSnap’ annual ranking of the top 100 Most News Heat Calprotectin Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2019, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

Calprotectin is a complex of the mammalian proteins S100A8 and S100A9. In the presence of calcium, calprotectin is capable of sequestering the transition metals iron, manganese and zinc via chelation. This metal sequestration affords the complex antimicrobial properties. Calprotectin is the only known antimicrobial manganese sequestration protein complex. Calprotectin comprises as much as 60% of the soluble protein content of the cytosol of a neutrophil, and it is secreted by an unknown mechanism during inflammation. Faecal calprotectin has been used to detect intestinal inflammation (colitis or enteritis) and can serve as a biomarker for inflammatory bowel diseases and Rheumatoid Arthritis. Other names for calprotectin include MRP8-MRP14, calgranulin A and B, cystic fibrosis antigen, L1, 60BB antigen, and 27E10 antigen.

1	Abivax SA	Île-de-France, France	Leptospirosis,Dengue virus,Typhoid fever, ...[+2]	news: 7
2	UC AB	Sweden	Decision-making,Public sector	news: 7
3	Euronext NV	Noord-Holland, Netherlands	Investment banking	news: 5
4	Landos Biopharma, Inc.	Virginia, United States	Health care,Clinical trial,Pharmacy and Therapeutics, ...[+2]	news: 5
5	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	news: 4
6	UC San Diego Health	California, United States	Health care	news: 4
7	Johnson & Johnson	New Jersey, United States	Health care,Medical equipment,Risperidone, ...[+2]	news: 3
8	Protalix Biotherapeutics, Inc.	New Jersey, United States	Plant cell,Medicine,Health care, ...[+2]	news: 3
9	RTW Investments LP	New York, United States	Asset management,Health care,Gene delivery, ...[+2]	news: 3
10	Perceptive Advisors LLC	New York, United States	Venture capital,Long/short equity,Biotechnology, ...[+2]	news: 3
11	PBM Capital Group LLC	Virginia, United States	Equity value,Asset management,Entrepreneurial spirit, ...[+2]	news: 3
12	European Medicines Agency	United Kingdom	Safety monitoring,Contract research organization,Laboratory testing, ...[+2]	news: 3
13	GSK Plc	United Kingdom	Health care,Clinical trial,Drug, ...[+2]	news: 2
14	Theravance Biopharma, Inc.	California, United States	Medicine,Health care,Bifunctional, ...[+2]	news: 2
15	Atara Biotherapeutics, Inc.	California, United States	Immunotherapy,Medicine,Health care, ...[+2]	news: 2
16	CHIESI Farmaceutici SpA	Emilia-Romagna, Italy	Inhaler,Neonatology,Medicine, ...[+2]	news: 2
17	Sofinnova Partners SAS	Île-de-France, France	Venture capital,Industrial biotechnology,Oncogene, ...[+2]	news: 2
18	Janssen, Inc.	Ontario, Canada	Cyclen,Ditropan xl	news: 2
19	Bruce Crohn LLC	Massachusetts, United States	Employee benefits	news: 2
20	McLaughlin Research Institute for Biomedical Sciences, Inc.	United States		news: 2
21	Biopharma LLC	Kiev City, Ukraine	Medicine,TNF inhibitor,Etanercept, ...[+2]	news: 2
22	Janssen Research & Development LLC	New Jersey, United States	Neuroscience,Oncology,Biotechnology, ...[+2]	news: 2
23	Compagnie de Saint-Gobain SA	Île-de-France, France	Thermal insulation,Glazing,Construction engineering, ...[+2]	news: 1
24	Medtronic Plc	Dublin, Ireland	Medical equipment,Health care,Pharmacy and Therapeutics, ...[+2]	news: 1
25	Samsung Electronics Co., Ltd.	South Korea	Computer hardware,Semiconductor,Software, ...[+2]	news: 1
26	Boston Scientific Corp.	Massachusetts, United States	Medical equipment,Catheter,Health care, ...[+2]	news: 1
27	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	news: 1
28	Koninklijke DSM NV	Netherlands	Animal nutrition,Health care,Biology, ...[+2]	news: 1
29	AbbVie, Inc.	Illinois, United States	Health care,Medicine,Biopharmaceutical, ...[+2]	news: 1
30	Eli Lilly & Co.	Indiana, United States	Medicine,Health care,Humalog Mix, ...[+2]	news: 1
31	Gilead Sciences, Inc.	California, United States	Medicine,Health care,Biopharmaceutical, ...[+2]	news: 1
32	Takeda Pharmaceutical Co., Ltd.	Osaka, Japan	Medicine,Health care,Clinical trial, ...[+2]	news: 1
33	Sysmex Corp.	Hokkaido, Japan	Clinical chemistry,Reagent,Medical equipment, ...[+2]	news: 1
34	UCB SA	Belgium	Epilepsy,Adalimumab,Drug, ...[+2]	news: 1
35	New Fortress Energy, Inc.	New York, United States	Regasification,Liquefaction,Petroleum industry	news: 1
36	Icahn Enterprises LP	New York, United States	Automotive engineering,Petroleum,Food packaging, ...[+2]	news: 1
37	Allergan Ltd. (Ireland)	Wisconsin, United States	Eye drop,Medicine,Health care, ...[+2]	news: 1
38	GlobalData Plc	United Kingdom	Cable television,Business information,Information technology consulting, ...[+1]	news: 1
39	DiaSorin SpA	Piemonte, Italy	Medicine,In vitro,Coronavirus, ...[+2]	news: 1
40	Shire Plc	Dublin, Ireland	Rare disease,Wellness Programs,Health care, ...[+2]	news: 1
41	Meridian Bioscience, Inc.	Ohio, United States	Medicine,Polymerase chain reaction,Diagnostic test, ...[+2]	news: 1
42	Celgene Corp.	New Jersey, United States	Health care,Cytogenetic Abnormality,Medicine, ...[+2]	news: 1
43	Bank of India	Maharashtra, India	Retail banking,Venture capital,National bank, ...[+2]	news: 1
44	Life Corp.	Osaka, Japan	Customer insight,Food products,Food industry, ...[+2]	news: 1
45	TAKARA & COMPANY LTD.	Tokyo, Japan	Advertising,Publication,Software development, ...[+2]	news: 1
46	KATO WORKS CO., LTD.	Tokyo, Japan	Mobile crane,Manufacturing engineering,Construction engineering, ...[+2]	news: 1
47	Green Cross Co., Ltd.	Fukuoka, Japan	Oil well,DNA vaccination,Oncology drugs, ...[+2]	news: 1
48	Celltrion, Inc.	South Korea	Automotive engineering,Health care,Biosimilar, ...[+2]	news: 1
49	Transaction Co., Ltd.	Kanagawa, Japan	Conference management,Sales management,Household goods, ...[+1]	news: 1
50	Innoviva, Inc.	California, United States	Asthma,Medicine,Pulmonary medicine, ...[+2]	news: 1
51	Truffle Capital SAS	Île-de-France, France	Venture capital,Financial innovation,Biochemistry, ...[+2]	news: 1
52	NEA Management Co. LLC	California, United States	Venture capital,Software as a service,Medical equipment, ...[+2]	news: 1
53	Boehringer Ingelheim GmbH	Rheinland-Pfalz, Germany	Medicine,Metered-dose inhaler,Inhaler, ...[+2]	news: 1
54	PI Industries Ltd.	Haryana, India	Fungicide,Pesticide,Chemical engineering, ...[+2]	news: 1
55	Airports of Thailand Public Co. Ltd.	Bangkok Metropolis, Thailand	Aviation,Aerotropolis,Public transport, ...[+2]	news: 1
56	ACG Management SAS	Provence-Alpes-Côte d'Azur, France	Self-administration,Cytokine,Venture capital, ...[+2]	news: 1
57	Dechert LLP	Pennsylvania, United States	Defense attorney,Legal case,Legal service, ...[+2]	news: 1
58	University Bancorp, Inc.	Michigan, United States	Time deposit,Ultrasonic sensor,Accelerometer, ...[+1]	news: 1
59	MedImmune LLC	Louisiana, United States	Medicine,Pharmacy and Therapeutics,Autoimmunity, ...[+2]	news: 1
60	Benitec Biopharma, Inc.	California, United States	Biotechnology,Genetic Medicine	news: 1
61	Kepler Cheuvreux SA	Île-de-France, France	Inter-dealer broker,Structured product,Management buyout, ...[+2]	news: 1
62	Kreos Capital Management (UK) Ltd.	United Kingdom	Insulin pump,Inhaler,Injector, ...[+2]	news: 1
63	Morgenthaler Management Corp.	California, United States	Venture capital,Oncogene,Oncology drugs, ...[+2]	news: 1
64	Theradiag SA	Île-de-France, France	Medicine,Beta-2 microglobulin,Pap test, ...[+2]	news: 1
65	Mindray Medical International Ltd.	Hunan Sheng, China	Hematology,Medicine,Medical equipment, ...[+2]	news: 1
66	National Car Rental System, Inc.	Texas, United States	Renting,Public transport,Building automation, ...[+2]	news: 1
67	CYduct Diagnostics, Inc.	Massachusetts, United States	Endoscopy,Morcellator,Medical equipment, ...[+2]	news: 1
68	Sheba Medical Center	Tel Aviv, Israel	Health care,Intubation,Tracheal tube, ...[+2]	news: 1
69	Sarstedt AG & Co. KG	Nordrhein-Westfalen, Germany	Blood collection,Medical equipment,Medicine, ...[+2]	news: 1
70	TiGenix NV	Vlaams-Brabant, Belgium	Clinical trial,Medical equipment,Health care, ...[+2]	news: 1
71	Janssen Pharmaceutica NV	Antwerpen, Belgium	Product design,Neuroscience,Health care, ...[+2]	news: 1
72	Celltrion Healthcare Co., Ltd.	South Korea	Biosimilar,Breakthrough therapy,Health care, ...[+2]	news: 1
73	WRP Asia Pacific Sdn Bhd	Selangor, Malaysia	Medical equipment	news: 1
74	Summit Therapeutics Ltd.	Oxfordshire, United Kingdom	Drug development,Drug discovery,Medical equipment, ...[+2]	news: 1
75	Glaxo Group Ltd.	Hounslow, United Kingdom	Food products,Medicine,Health care	news: 1
76	London & Cambridge Properties Ltd.	St. Helens, United Kingdom	Real estate development	news: 1
77	Millennium Pharmaceuticals, Inc.	Massachusetts, United States	Oncology,Health care,Monoclonal antibody, ...[+2]	news: 1
78	Unitel Corp.	Ulaanbaatar, Mongolia	Telecommunications,Mobile service,Broadband, ...[+2]	news: 1
79	Public Health Solutions	Sachsen, Germany	Simulation software,Social network,Social media	news: 1
80	RTW, Inc.	Minnesota, United States	Insurance carriers	news: 1
81	STARTUP TARGET PharmaSolutions, Inc.	North Carolina, United States	Health care,Transcriptome,microRNA, ...[+2]	news: 1
82	Meridian Co., Ltd.	South Korea	Medical equipment,Pulse wave,Medicine, ...[+2]	news: 1
83	HemoCue AB	Sweden	Point-of-care testing,Medical equipment,Health care, ...[+2]	news: 1
84	Euronext Paris SA	Île-de-France, France	Market data	news: 1
85	Solebury Trout LLC	Connecticut, United States	Market access,Corporate communication,Capital market, ...[+2]	news: 1
86	Urovant Sciences Ltd.	United Kingdom	Biopharmaceutical,Medicine,Cell therapy, ...[+2]	news: 1
87	Centre of Telecommunications Research	Ontario, Canada	Telecommunications	news: 1
88	Action Potential Venture Capital	Massachusetts, United States	Action potential,Asset management,Deep brain stimulator, ...[+2]	news: 1
89	Vivelix Pharmaceuticals, Ltd.	Bermuda	Gastrointestinal agent,Medicine,Hepatology, ...[+1]	news: 1
90	The Trout Group LLC	New York, United States	Knowledge base,Exposure,Biotechnology	news: 1
91	Dimagi, Inc.	Massachusetts, United States	Software,Drug repositioning,Social influence, ...[+2]	news: 1
92	enGene, Inc.	British Columbia, Canada	Diabetes Therapy,Medicine,Health care, ...[+2]	news: 1
93	OUP (Osage University Partners)	Pennsylvania, United States	Venture capital,Medical equipment,Software	news: 1
94	Commcare AG	Zürich, Switzerland	Telecommunications,Intranet,Medical prescription, ...[+2]	news: 1
95	SetPoint Medical Corp.	California, United States	Medical equipment,Vagus nerve stimulation,Neuroscience, ...[+2]	news: 1
96	STARTUP Lyndra Therapeutics, Inc.	Massachusetts, United States	Clinical trial,Software,Health care, ...[+2]	news: 1
97	MacDougall Advisors, Inc.	Massachusetts, United States	Advertising,Health care,Corporate communication, ...[+1]	news: 1
98	Perceptive Group Ltd.	Auckland, New Zealand	Customer intelligence,Market research,Decision-making	news: 1
99	Xontogeny LLC	Massachusetts, United States	New Ventures,Medicine	news: 1
100	Cairn Financial Advisers LLP	United Kingdom		news: 1