Top 100 Key Players companies in Calprotectin by Most News Heat in the world in 2021 – Discovery

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The Calprotectin top 100 is Discovery PatSnap’ annual ranking of the top 100 Most News Heat Calprotectin Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2021, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

Calprotectin is a complex of the mammalian proteins S100A8 and S100A9. In the presence of calcium, calprotectin is capable of sequestering the transition metals iron, manganese and zinc via chelation. This metal sequestration affords the complex antimicrobial properties. Calprotectin is the only known antimicrobial manganese sequestration protein complex. Calprotectin comprises as much as 60% of the soluble protein content of the cytosol of a neutrophil, and it is secreted by an unknown mechanism during inflammation. Faecal calprotectin has been used to detect intestinal inflammation (colitis or enteritis) and can serve as a biomarker for inflammatory bowel diseases and Rheumatoid Arthritis. Other names for calprotectin include MRP8-MRP14, calgranulin A and B, cystic fibrosis antigen, L1, 60BB antigen, and 27E10 antigen.

1	UC AB	Sweden	Decision-making,Public sector	news: 24
2	Abivax SA	Île-de-France, France	Leptospirosis,Dengue virus,Typhoid fever, ...[+2]	news: 12
3	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	news: 8
4	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	news: 7
5	Euronext NV	Noord-Holland, Netherlands	Investment banking	news: 7
6	Landos Biopharma, Inc.	Virginia, United States	Health care,Clinical trial,Pharmacy and Therapeutics, ...[+2]	news: 7
7	Galapagos NV	Belgium	Clinical trial,Small molecule,Biotechnology, ...[+2]	news: 6
8	UC San Diego Health	California, United States	Health care	news: 4
9	GSK Plc	United Kingdom	Health care,Clinical trial,Drug, ...[+2]	news: 3
10	AbbVie, Inc.	Illinois, United States	Health care,Medicine,Biopharmaceutical, ...[+2]	news: 3
11	Gilead Sciences, Inc.	California, United States	Medicine,Health care,Biopharmaceutical, ...[+2]	news: 3
12	Takeda Pharmaceutical Co., Ltd.	Osaka, Japan	Medicine,Health care,Clinical trial, ...[+2]	news: 3
13	Protalix Biotherapeutics, Inc.	New Jersey, United States	Plant cell,Medicine,Health care, ...[+2]	news: 3
14	RTW Investments LP	New York, United States	Asset management,Health care,Gene delivery, ...[+2]	news: 3
15	Perceptive Advisors LLC	New York, United States	Venture capital,Long/short equity,Biotechnology, ...[+2]	news: 3
16	PBM Capital Group LLC	Virginia, United States	Equity value,Asset management,Entrepreneurial spirit, ...[+2]	news: 3
17	STARTUP Blade Therapeutics, Inc.	California, United States	Acquired diseases,Medicine,Health care, ...[+2]	news: 3
18	ProciseDx LLC	California, United States	Retail clinic,Software,Enterprise software, ...[+2]	news: 3
19	Abbott Laboratories	Illinois, United States	Medical equipment,Health care,Emergency medicine, ...[+2]	news: 2
20	Barclays Plc	United Kingdom	Investment banking,Retail banking,Underwriting, ...[+2]	news: 2
21	Samsung Electronics Co., Ltd.	South Korea	Computer hardware,Semiconductor,Software, ...[+2]	news: 2
22	Thermo Fisher Scientific, Inc.	Massachusetts, United States	Biology,Medical equipment,Reagent, ...[+2]	news: 2
23	Informa Plc	United Kingdom	Publishing,Information technology consulting,Business-to-business, ...[+2]	news: 2
24	Agilent Technologies, Inc.	California, United States	Genomics,Computer hardware,Semiconductor, ...[+2]	news: 2
25	Sysmex Corp.	Hokkaido, Japan	Clinical chemistry,Reagent,Medical equipment, ...[+2]	news: 2
26	GlobalData Plc	United Kingdom	Cable television,Business information,Information technology consulting, ...[+1]	news: 2
27	DiaSorin SpA	Piemonte, Italy	Medicine,In vitro,Coronavirus, ...[+2]	news: 2
28	Shire Plc	Dublin, Ireland	Rare disease,Wellness Programs,Health care, ...[+2]	news: 2
29	Theravance Biopharma, Inc.	California, United States	Medicine,Health care,Bifunctional, ...[+2]	news: 2
30	Atara Biotherapeutics, Inc.	California, United States	Immunotherapy,Medicine,Health care, ...[+2]	news: 2
31	Gossamer Bio, Inc.	California, United States	Biopharmaceutical,Medicine,Health care, ...[+2]	news: 2
32	Biosynex SA	Alsace, France	Medicine,Membrane,Tropical disease, ...[+2]	news: 2
33	CHIESI Farmaceutici SpA	Emilia-Romagna, Italy	Inhaler,Neonatology,Medicine, ...[+2]	news: 2
34	Sofinnova Partners SAS	Île-de-France, France	Venture capital,Industrial biotechnology,Oncogene, ...[+2]	news: 2
35	CODI-M Co., Ltd.	South Korea	Automation,Manufacturing engineering,Industrial engineering, ...[+2]	news: 2
36	MPM Capital Inc	Massachusetts, United States	Biology,Health care,Filling-in, ...[+2]	news: 2
37	Kepler Cheuvreux SA	Île-de-France, France	Inter-dealer broker,Structured product,Management buyout, ...[+2]	news: 2
38	Kreos Capital Management (UK) Ltd.	United Kingdom	Insulin pump,Inhaler,Injector, ...[+2]	news: 2
39	Nestle Health Science SA	Vaud, Switzerland	Nutrition,Health care,Clinical nutrition, ...[+2]	news: 2
40	Janssen Pharmaceutica NV	Antwerpen, Belgium	Product design,Neuroscience,Health care, ...[+2]	news: 2
41	Celltrion Healthcare Co., Ltd.	South Korea	Biosimilar,Breakthrough therapy,Health care, ...[+2]	news: 2
42	Mars One Ventures AG	Switzerland	Human settlement	news: 2
43	STARTUP Fda Educator	California, United States		news: 2
44	Biomedical Research, Inc.	MD, US	Neuropathic pain,Opioid,Analgesic, ...[+2]	news: 2
45	Gossamer Ltd.	New York, United States		news: 2
46	The company Japan	Tokyo, Japan	Wireless sensor network,Graphic design,Web design	news: 2
47	Bruce Crohn LLC	Massachusetts, United States	Employee benefits	news: 2
48	McLaughlin Research Institute for Biomedical Sciences, Inc.	United States		news: 2
49	Association Française Des Marchés Financiers	France	Financial market	news: 2
50	Biopharma LLC	Kiev City, Ukraine	Medicine,TNF inhibitor,Etanercept, ...[+2]	news: 2
51	Siemens AG	Bayern, Germany	Power transmission,Electronics,Turbine, ...[+2]	news: 1
52	Johnson & Johnson	New Jersey, United States	Health care,Medical equipment,Risperidone, ...[+2]	news: 1
53	Bank of America Corp.	North Carolina, United States	Investment banking,Underwriting,Asset and liability management, ...[+2]	news: 1
54	Société Générale SA	Île-de-France, France	Real economy,Payment system,Online payment, ...[+2]	news: 1
55	Nestlé SA	Vaud, Switzerland	Ice cream,Nutrition,Cosmetics, ...[+2]	news: 1
56	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	news: 1
57	Danaher Corp.	District of Columbia, United States	Health care,Biology,Medical equipment, ...[+2]	news: 1
58	HP, Inc.	California, United States	Software,Computer hardware,Enterprise software, ...[+2]	news: 1
59	Medtronic Plc	Dublin, Ireland	Medical equipment,Health care,Pharmacy and Therapeutics, ...[+2]	news: 1
60	Morgan Stanley	New York, United States	Investment banking,Asset management,Emotional security, ...[+2]	news: 1
61	Becton, Dickinson & Co.	Haryana, India	Medical equipment,Health care,Surgical Specialty, ...[+2]	news: 1
62	Kinder Morgan, Inc.	Texas, United States	Petroleum industry,Natural gas,Petroleum product, ...[+2]	news: 1
63	Boston Scientific Corp.	Massachusetts, United States	Medical equipment,Catheter,Health care, ...[+2]	news: 1
64	Koninklijke DSM NV	Netherlands	Animal nutrition,Health care,Biology, ...[+2]	news: 1
65	Eurofins Scientific SE	Luxembourg, Luxembourg	Biology,Genomics,Food safety, ...[+2]	news: 1
66	Eli Lilly & Co.	Indiana, United States	Medicine,Health care,Humalog Mix, ...[+2]	news: 1
67	AstraZeneca Plc	Cambridgeshire, United Kingdom	Medicine,Health care,Side effect, ...[+2]	news: 1
68	Roche Holding AG	Basel-Stadt, Switzerland	Drug,Clinical chemistry,Medicine, ...[+2]	news: 1
69	Cargill, Inc.	Minnesota, United States	Agriculture,Food industry,Broiler, ...[+2]	news: 1
70	Cowen, Inc.	New York, United States	Investment banking,Alternative investment,Assets under management, ...[+2]	news: 1
71	Bank of Montreal	Ontario, Canada	Retail banking,Mass affluent,Corporate services, ...[+2]	news: 1
72	Universal Corp.	Virginia, United States	Nicotiana tabacum,Smoke,Smokeless tobacco, ...[+2]	news: 1
73	Fresh Del Monte Produce, Inc.	United States	Grapefruit juice,Pickling,Food processing, ...[+2]	news: 1
74	QIAGEN NV	Netherlands	Assay,Molecular diagnostics,Coronavirus, ...[+2]	news: 1
75	UCB SA	Belgium	Epilepsy,Adalimumab,Drug, ...[+2]	news: 1
76	UBS Group AG	ZURICH, Switzerland	Investment banking,Asset management,Venture capital, ...[+2]	news: 1
77	New Fortress Energy, Inc.	New York, United States	Regasification,Liquefaction,Petroleum industry	news: 1
78	Information Services Group, Inc.	Connecticut, United States	Information technology consulting,Change management,Insurance industry, ...[+2]	news: 1
79	Norfolk Southern Corp.	Virginia, United States	Public transport,Railway engineering,Military logistics, ...[+2]	news: 1
80	US Xpress Enterprises, Inc.	Tennessee, United States	Public transport,Military logistics,Parcel delivery, ...[+2]	news: 1
81	Icahn Enterprises LP	New York, United States	Automotive engineering,Petroleum,Food packaging, ...[+2]	news: 1
82	Allergan Ltd. (Ireland)	Wisconsin, United States	Eye drop,Medicine,Health care, ...[+2]	news: 1
83	Aster DM Healthcare Ltd.	United Arab Emirates	Pharmacy,Customer insight,Health care, ...[+2]	news: 1
84	Regeneron Pharmaceuticals, Inc.	New York, United States	Monoclonal antibody,Clinical trial,Cholesterol, ...[+2]	news: 1
85	JK Holdings Co., Ltd.	Tokyo, Japan	Wood processing,Building material,Submersible pump, ...[+2]	news: 1
86	Grantham, Mayo, Van Otterloo & Co. LLC	Massachusetts, United States	Asset management,Impact investing,Mean reversion, ...[+2]	news: 1
87	Google LLC	California, United States	Advertising,Enterprise software,Search engine, ...[+2]	news: 1
88	Oppenheimer Holdings, Inc.	New York, United States	Asset management,Investment banking,Market maker, ...[+2]	news: 1
89	Meridian Bioscience, Inc.	Ohio, United States	Medicine,Polymerase chain reaction,Diagnostic test, ...[+2]	news: 1
90	Moderna, Inc.	Massachusetts, United States	Health care,Messenger RNA,Coronavirus disease 2019 (COVID-19), ...[+2]	news: 1
91	bioMérieux SA	Rhône-Alpes, France	Diagnostic system,Medicine,Coronavirus, ...[+2]	news: 1
92	Celgene Corp.	New Jersey, United States	Health care,Cytogenetic Abnormality,Medicine, ...[+2]	news: 1
93	Bank of India	Maharashtra, India	Retail banking,Venture capital,National bank, ...[+2]	news: 1
94	Life Corp.	Osaka, Japan	Customer insight,Food products,Food industry, ...[+2]	news: 1
95	MRI Software LLC	Ohio, United States	Software,Property management,Client relationship, ...[+2]	news: 1
96	Jacobson Pharma Corp. Ltd.	Hong Kong SAR, China	Generic drug,Medicine,Health care, ...[+2]	news: 1
97	TAKARA & COMPANY LTD.	Tokyo, Japan	Advertising,Publication,Software development, ...[+2]	news: 1
98	BMC Software, Inc.	Texas, United States	Software,Cloud computing,Information technology consulting, ...[+2]	news: 1
99	KATO WORKS CO., LTD.	Tokyo, Japan	Mobile crane,Manufacturing engineering,Construction engineering, ...[+2]	news: 1
100	Green Cross Co., Ltd.	Fukuoka, Japan	Oil well,DNA vaccination,Oncology drugs, ...[+2]	news: 1