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Top 100 Key Players companies in Chemical formula
by Highest Patent Value in the world in 2022

The Chemical formula top 100 is Discovery PatSnap’ annual ranking of the top 100 Highest Patent Value Chemical formula Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2022, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
A chemical formula is a way of presenting information about the chemical proportions of atoms that constitute a particular chemical compound or molecule, using chemical element symbols, numbers, and sometimes also other symbols, such as parentheses, dashes, brackets, commas and plus (+) and minus (−) signs. These are limited to a single typographic line of symbols, which may include subscripts and superscripts. A chemical formula is not a chemical name, and it contains no words. Although a chemical formula may imply certain simple chemical structures, it is not the same as a full chemical structural formula. Chemical formulas can fully specify the structure of only the simplest of molecules and chemical substances, and are generally more limited in power than are chemical names and structural formulas.

Key Players

Fast-growings

Startups & Unicorns

New Entrants

Ranking Year:

2022

2021

2020

2019

2018

Region:

Global

China

Japan

India

Italy

United States

Ireland

Germany

Switzerland

Netherlands

United Kingdom

France

Singapore

Canada

Belgium

South Korea

Australia

Spain

Ranking:

Most Patent Filings

Highest Patent Value

Most Sep Patents

Most Patent Citation

Most Research Publications

Most Literature Citation

Most Market Reports

Most News Heat

#
Company Name
Region
Tech Topics
Total
1
Istituto di Ricerche di Biologia Molecolare P. Angeletti SpA
Italy
Avg patent value: 10.86 M
2
Wyeth LLC
New Jersey, United States
Avg patent value: 10.76 M
3
Dignity Sciences Ltd.
Dublin, Ireland
Atopic dermatitis,Inflammatory disorder,Dermatology,
...[+2]
Avg patent value: 10.35 M
4
Kronos Bio, Inc.
California, United States
Biopharmaceutical,Chemical engineering,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 10.19 M
5
Adverio Pharma GmbH
Berlin, Germany
Avg patent value: 10.16 M
6
Addex Pharma SA
Switzerland
Allosteric modulator,Medicine
Avg patent value: 9.57 M
7
Medivation Technologies LLC
California, United States
Herb,Botanical drug
Avg patent value: 9.53 M
8
Achaogen, Inc.
California, United States
Antibiotics,Health care,Medicine,
...[+2]
Avg patent value: 9.28 M
9
Daiichi Sankyo Europe GmbH
Bayern, Germany
Medicine
Avg patent value: 9.16 M
10
ARIAD Pharmaceuticals, Inc.
Massachusetts, United States
Biotechnology,Health care,Cancer Medicine,
...[+2]
Avg patent value: 9.00 M
11
Signal Pharmaceuticals LLC
California, United States
Intracellular signalling,Medicine,Intracellular,
...[+1]
Avg patent value: 8.96 M
12
Novartis Pharma GmbH
WI, AT
Pharmacy,Drug,Medicine
Avg patent value: 8.96 M
13
Array BioPharma, Inc.
Colorado, United States
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 8.84 M
14
Nektar Therapeutics
California, United States
Biopharmaceutical,Chemical engineering,Health care,
...[+2]
Avg patent value: 8.84 M
15
Nektar Therapeutics AL Corp.
Alabama, United States
Ethylene glycol,Ethylene,Chemical engineering
Avg patent value: 8.84 M
16
Merck Sharp & Dohme BV
Noord-Brabant, Netherlands
Drug,Medicine
Avg patent value: 8.75 M
17
Millennium Pharmaceuticals, Inc.
Massachusetts, United States
Oncology,Health care,Monoclonal antibody,
...[+2]
Avg patent value: 8.66 M
18
Celgene CAR LLC
Delaware, United States
Cancer,Biotechnology,Agriculture,
...[+2]
Avg patent value: 8.53 M
19
FUJIFILM Toyama Chemical Co., Ltd.
Tokyo, Japan
Pharmacy,Coronavirus disease 2019 (COVID-19),Allopregnanolone,
...[+2]
Avg patent value: 8.49 M
20
Rempex Pharmaceuticals, Inc.
California, United States
Antibiotic resistance,Drug,Pharmacy,
...[+2]
Avg patent value: 8.44 M
21
Infinity Pharmaceuticals, Inc.
Massachusetts, United States
Medicine,Clinical trial,Hsp90,
...[+2]
Avg patent value: 8.39 M
22
G1 Therapeutics, Inc.
North Carolina, United States
Health care,Software development,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 8.38 M
23
NuCana Plc
Edinburgh, United Kingdom
Oncology,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 8.35 M
24
Alnylam Pharmaceuticals, Inc.
Massachusetts, United States
RNA interference,Medicine,Health care,
...[+2]
Avg patent value: 8.32 M
25
Aragon Pharmaceuticals, Inc.
California, United States
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 8.23 M
26
Hunt Perovskite Technologies LLC
Texas, United States
Energy technology,Semiconductor,Capacitor,
...[+2]
Avg patent value: 8.21 M
27
Aventis Agriculture SA
Île-de-France, France
Medicine,Biology,Pharmacy,
...[+2]
Avg patent value: 8.16 M
28
Ligand Pharmaceuticals, Inc.
California, United States
Ligand,Medicine,Health care,
...[+2]
Avg patent value: 8.11 M
29
Spexis Ltd.
Basel-Landschaft, Switzerland
Health care,Antibiotic resistance,Pseudomonas infection,
...[+2]
Avg patent value: 8.04 M
30
Altos Therapeutics LLC
California, United States
Avg patent value: 8.01 M
31
SCOHIA PHARMA, Inc.
Kanagawa, Japan
Health care,Patiromer,Cardiovascular agent,
...[+2]
Avg patent value: 7.98 M
32
Laboratoires Fournier SAS
Île-de-France, France
Medicine
Avg patent value: 7.94 M
33
BeiGene Ltd.
Beijing Shi, China
Biotechnology,Biopharmaceutical,Biology,
...[+2]
Avg patent value: 7.86 M
34
Allergan Sales LLC
Illinois, United States
Medical equipment,Drug,Medicine
Avg patent value: 7.79 M
35
Cayman Chemical Co., Inc.
Michigan, United States
Biology,Health care,Assay,
...[+2]
Avg patent value: 7.48 M
36
Cosmo Technologies Ltd.
Dublin, Ireland
Medicine
Avg patent value: 7.48 M
37
Myometrics, LLC
United States
Avg patent value: 7.48 M
38
Kotobuki Pharmaceutical Co. Ltd.
Shizuoka, Japan
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 7.46 M
39
Ventana Medical Systems, Inc.
Arizona, United States
Medical equipment,Health care,Digital pathology,
...[+2]
Avg patent value: 7.43 M
40
Vertex Pharmaceuticals, Inc.
Massachusetts, United States
Health care,Medicine,Cystic fibrosis,
...[+2]
Avg patent value: 7.42 M
41
Gilead Sciences, Inc.
California, United States
Medicine,Health care,Biopharmaceutical,
...[+2]
Avg patent value: 7.38 M
42
Pfizer Anti-Infectives AB
Stockholm, Sweden
Avg patent value: 7.29 M
43
Esanex, Inc.
Indiana, United States
Hsp90,Software development,Chronic lymphocytic leukemia,
...[+2]
Avg patent value: 7.28 M
44
Cytokinetics, Inc.
California, United States
Cytoskeleton,Clinical trial,Medicine,
...[+2]
Avg patent value: 7.28 M
45
Celgene Corp.
New Jersey, United States
Health care,Cytogenetic Abnormality,Medicine,
...[+2]
Avg patent value: 7.25 M
46
AFFiRiS AG
Niederösterreich, Austria
Medicine,Health care,Peptide,
...[+2]
Avg patent value: 7.19 M
47
Curia Global, Inc.
New York, United States
Drug discovery,Manufacturing organization,Biotechnology,
...[+2]
Avg patent value: 7.10 M
48
Curis, Inc.
Massachusetts, United States
Drug,Health care,Drug development,
...[+2]
Avg patent value: 7.10 M
49
Wave Life Sciences Ltd.
Central Singapore, Singapore
Biotechnology,Nucleic acid,Medicine,
...[+2]
Avg patent value: 7.06 M
50
AbbVie Bahamas Ltd.
The Bahamas
Avg patent value: 7.06 M
51
Janssen Pharmaceuticals, Inc.
New Jersey, United States
Drug,Medicine,Risperdal Consta,
...[+2]
Avg patent value: 7.01 M
52
Anacor Pharmaceuticals, Inc.
California, United States
Medicine,Health care,Boron,
...[+2]
Avg patent value: 6.99 M
53
ViiV Healthcare UK Ltd.
United Kingdom
Transdermal patch,Intellectual property,Medical equipment,
...[+2]
Avg patent value: 6.99 M
54
Alkermes Pharma Ireland Ltd.
Ireland
Medicine
Avg patent value: 6.97 M
55
WisTa Laboratories Ltd.
Central Singapore, Singapore
Avg patent value: 6.92 M
56
Innoviva, Inc.
California, United States
Asthma,Medicine,Pulmonary medicine,
...[+2]
Avg patent value: 6.84 M
57
Arbutus Biopharma Corp.
British Columbia, Canada
Medicine,Health care,Drug,
...[+2]
Avg patent value: 6.83 M
58
Tobira Therapeutics, Inc.
New Jersey, United States
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 6.81 M
59
FORMA Therapeutics, Inc.
Massachusetts, United States
Health care,Oncology drugs,Drug discovery,
...[+2]
Avg patent value: 6.69 M
60
Taro Pharmaceuticals, Inc.
Ontario, Canada
Medicine,Generic drug,Ifosfamide,
...[+2]
Avg patent value: 6.63 M
61
Cytec Technology Corp.
New Jersey, United States
Avg patent value: 6.63 M
62
Incyte Corp.
Delaware, United States
Drug discovery,Medical equipment,Medicine,
...[+2]
Avg patent value: 6.63 M
63
Plexxikon, Inc.
California, United States
Health care,Medicine,Oncology drugs,
...[+2]
Avg patent value: 6.62 M
64
Axys Pharmaceuticals, Inc.
California, United States
Small molecule,Pharmacy and Therapeutics,Medicine
Avg patent value: 6.62 M
65
Merck Frosst Canada & Co.
Canada
Avg patent value: 6.62 M
66
Galapagos NV
Belgium
Clinical trial,Small molecule,Biotechnology,
...[+2]
Avg patent value: 6.57 M
67
Achillion Pharmaceuticals, Inc.
Pennsylvania, United States
Complement system,Pharmacy and Therapeutics,Medicine,
...[+2]
Avg patent value: 6.56 M
68
Amgen, Inc.
California, United States
Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER,
...[+2]
Avg patent value: 6.53 M
69
Japan Tobacco, Inc.
Tokyo, Japan
Nicotiana tabacum,Cigarillo,Food sector,
...[+2]
Avg patent value: 6.52 M
70
Janssen Sciences Ireland Unlimited Co.
Ireland
Avg patent value: 6.52 M
71
OliPass Corp.
Chungcheongnam-do, South Korea
Gene,Biology,Biological product,
...[+2]
Avg patent value: 6.47 M
72
SARcode Bioscience, Inc.
California, United States
Medicine,Health care,Ophthalmology,
...[+2]
Avg patent value: 6.46 M
73
Merck Canada, Inc.
Canada
Health care,Cancer
Avg patent value: 6.44 M
74
Sumika Polycarbonate Ltd.
Tokyo, Japan
Polycarbonate,Synthetic rubber,Chemical engineering,
...[+2]
Avg patent value: 6.41 M
75
Allergan, Inc.
CA, US
Over-the-counter,Dermatology,Botanical drug,
...[+2]
Avg patent value: 6.37 M
76
Biogen MA, Inc.
Massachusetts, United States
Medicine,Drug,Developmental biology,
...[+2]
Avg patent value: 6.33 M
77
Novartis AG
Basel-Stadt, Switzerland
Dosage form,Health care,Medicine,
...[+2]
Avg patent value: 6.28 M
78
Fibrotech Therapeutics Pty Ltd.
Victoria, Australia
Kidney disease,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 6.26 M
79
Toyama Chemical Co., Ltd.
Tokyo, Japan
Pharmacy,Drug,Certolizumab pegol,
...[+2]
Avg patent value: 6.22 M
80
AbbVie BV
Netherlands
Medicine
Avg patent value: 6.21 M
81
Xeros Ltd.
United Kingdom
Artificial intelligence,Portable water purification,Clean technology,
...[+2]
Avg patent value: 6.20 M
82
AbbVie, Inc.
Illinois, United States
Health care,Medicine,Biopharmaceutical,
...[+2]
Avg patent value: 6.16 M
83
Zoetis Services LLC
New Jersey, United States
Drug,Medicine,Vertical farming,
...[+2]
Avg patent value: 6.11 M
84
Ogeda SA
Brussels Hoofdstedelijk Gewest, Belgium
Drug discovery,Medicine,Health care,
...[+2]
Avg patent value: 6.05 M
85
Dizal (Jiangsu) Pharmaceutical Co., Ltd.
Jiangsu Sheng, China
Medicine
Avg patent value: 6.04 M
86
Alkahest, Inc.
California, United States
Alkahest,Health care,Plasma therapy,
...[+2]
Avg patent value: 6.02 M
87
CHINOIN Zrt
Budapest, Hungary
Social assistance,Medicine,Prescription drug
Avg patent value: 6.02 M
88
Otsuka Pharmaceutical Factory, Inc.
Tokushima, Japan
Parenteral nutrition,Human nutrition,Drug,
...[+2]
Avg patent value: 5.98 M
89
Aurigene Discovery Technologies Ltd.
Karnataka, India
Biotechnology,Medical equipment,Drug discovery,
...[+2]
Avg patent value: 5.96 M
90
Karyopharm Therapeutics, Inc.
Massachusetts, United States
Medicine,Health care,Multiple myeloma,
...[+2]
Avg patent value: 5.93 M
91
Saudi Arabian Oil Co.
Saudi Arabia
Natural gas,Petrochemical,Petroleum industry,
...[+2]
Avg patent value: 5.89 M
92
PTC Therapeutics, Inc.
New Jersey, United States
Pharmacy and Therapeutics,Medicine,Health care,
...[+2]
Avg patent value: 5.89 M
93
ImmunoGen, Inc.
Massachusetts, United States
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 5.85 M
94
Takeda Pharmaceutical Co., Ltd.
Osaka, Japan
Medicine,Health care,Clinical trial,
...[+2]
Avg patent value: 5.82 M
95
Takeda Chemical Industries Ltd.
Japan
Pharmaceutical drug,Botanical drug,Herb
Avg patent value: 5.82 M
96
Seagen Inc.
Washington, United States
Antibody-drug conjugate,Medicine,Health care,
...[+2]
Avg patent value: 5.81 M
97
Alltech, Inc.
Kentucky, United States
Physical fitness,Health care,Agriculture,
...[+2]
Avg patent value: 5.79 M
98
Heptares Therapeutics Ltd.
United Kingdom
Medicine,Pharmacy and Therapeutics,Receptor,
...[+2]
Avg patent value: 5.76 M
99
PolyPeptide Laboratories Holding (PPL) AB
Skåne, Sweden
Peptide,Custom peptide synthesis,Peptide synthesis
Avg patent value: 5.76 M
100
Entasis Therapeutics Ltd.
United Kingdom
Drug,Medicine
Avg patent value: 5.76 M

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