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Top 100 Key Players companies in Chemical formula
by Highest Patent Value in the United States in 2022

The Chemical formula top 100 is Discovery PatSnap’ annual ranking of the top 100 Highest Patent Value Chemical formula Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2022, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
A chemical formula is a way of presenting information about the chemical proportions of atoms that constitute a particular chemical compound or molecule, using chemical element symbols, numbers, and sometimes also other symbols, such as parentheses, dashes, brackets, commas and plus (+) and minus (−) signs. These are limited to a single typographic line of symbols, which may include subscripts and superscripts. A chemical formula is not a chemical name, and it contains no words. Although a chemical formula may imply certain simple chemical structures, it is not the same as a full chemical structural formula. Chemical formulas can fully specify the structure of only the simplest of molecules and chemical substances, and are generally more limited in power than are chemical names and structural formulas.

Key Players

Fast-growings

Startups & Unicorns

New Entrants

Ranking Year:

2022

2021

2020

2019

2018

Region:

Global

China

Japan

India

Italy

United States

Ireland

Germany

Switzerland

Netherlands

United Kingdom

France

Singapore

Canada

Belgium

South Korea

Australia

Spain

Ranking:

Most Patent Filings

Highest Patent Value

Most Patent Citation

Most Research Publications

Most Literature Citation

Most Market Reports

Most News Heat

#
Company Name
Region
Tech Topics
Total
1
Wyeth LLC
New Jersey, United States
Avg patent value: 10.76 M
2
Kronos Bio, Inc.
California, United States
Biopharmaceutical,Chemical engineering,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 10.19 M
3
Medivation Technologies LLC
California, United States
Herb,Botanical drug
Avg patent value: 9.53 M
4
Achaogen, Inc.
California, United States
Antibiotics,Health care,Medicine,
...[+2]
Avg patent value: 9.28 M
5
ARIAD Pharmaceuticals, Inc.
Massachusetts, United States
Biotechnology,Health care,Cancer Medicine,
...[+2]
Avg patent value: 9.00 M
6
Signal Pharmaceuticals LLC
California, United States
Intracellular signalling,Medicine,Intracellular,
...[+1]
Avg patent value: 8.96 M
7
Array BioPharma, Inc.
Colorado, United States
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 8.84 M
8
Nektar Therapeutics
California, United States
Biopharmaceutical,Chemical engineering,Health care,
...[+2]
Avg patent value: 8.84 M
9
Nektar Therapeutics AL Corp.
Alabama, United States
Ethylene glycol,Ethylene,Chemical engineering
Avg patent value: 8.84 M
10
Millennium Pharmaceuticals, Inc.
Massachusetts, United States
Oncology,Health care,Monoclonal antibody,
...[+2]
Avg patent value: 8.66 M
11
Celgene CAR LLC
Delaware, United States
Cancer,Biotechnology,Agriculture,
...[+2]
Avg patent value: 8.53 M
12
Rempex Pharmaceuticals, Inc.
California, United States
Antibiotic resistance,Drug,Pharmacy,
...[+2]
Avg patent value: 8.44 M
13
Infinity Pharmaceuticals, Inc.
Massachusetts, United States
Medicine,Clinical trial,Hsp90,
...[+2]
Avg patent value: 8.39 M
14
G1 Therapeutics, Inc.
North Carolina, United States
Health care,Software development,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 8.38 M
15
Alnylam Pharmaceuticals, Inc.
Massachusetts, United States
RNA interference,Medicine,Health care,
...[+2]
Avg patent value: 8.32 M
16
Aragon Pharmaceuticals, Inc.
California, United States
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 8.23 M
17
Hunt Perovskite Technologies LLC
Texas, United States
Energy technology,Semiconductor,Capacitor,
...[+2]
Avg patent value: 8.21 M
18
Ligand Pharmaceuticals, Inc.
California, United States
Ligand,Medicine,Health care,
...[+2]
Avg patent value: 8.11 M
19
Altos Therapeutics LLC
California, United States
Avg patent value: 8.01 M
20
Allergan Sales LLC
Illinois, United States
Medical equipment,Drug,Medicine
Avg patent value: 7.79 M
21
Cayman Chemical Co., Inc.
Michigan, United States
Biology,Health care,Assay,
...[+2]
Avg patent value: 7.48 M
22
Myometrics, LLC
United States
Avg patent value: 7.48 M
23
Ventana Medical Systems, Inc.
Arizona, United States
Medical equipment,Health care,Digital pathology,
...[+2]
Avg patent value: 7.43 M
24
Vertex Pharmaceuticals, Inc.
Massachusetts, United States
Health care,Medicine,Cystic fibrosis,
...[+2]
Avg patent value: 7.42 M
25
Gilead Sciences, Inc.
California, United States
Medicine,Health care,Biopharmaceutical,
...[+2]
Avg patent value: 7.38 M
26
Cytokinetics, Inc.
California, United States
Cytoskeleton,Clinical trial,Medicine,
...[+2]
Avg patent value: 7.28 M
27
Celgene Corp.
New Jersey, United States
Health care,Cytogenetic Abnormality,Medicine,
...[+2]
Avg patent value: 7.25 M
28
Curia Global, Inc.
New York, United States
Drug discovery,Manufacturing organization,Biotechnology,
...[+2]
Avg patent value: 7.10 M
29
Curis, Inc.
Massachusetts, United States
Drug,Health care,Drug development,
...[+2]
Avg patent value: 7.10 M
30
Janssen Pharmaceuticals, Inc.
New Jersey, United States
Drug,Medicine,Risperdal Consta,
...[+2]
Avg patent value: 7.01 M
31
Anacor Pharmaceuticals, Inc.
California, United States
Medicine,Health care,Boron,
...[+2]
Avg patent value: 6.99 M
32
Innoviva, Inc.
California, United States
Asthma,Medicine,Pulmonary medicine,
...[+2]
Avg patent value: 6.84 M
33
Tobira Therapeutics, Inc.
New Jersey, United States
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 6.81 M
34
FORMA Therapeutics, Inc.
Massachusetts, United States
Health care,Oncology drugs,Drug discovery,
...[+2]
Avg patent value: 6.69 M
35
Cytec Technology Corp.
New Jersey, United States
Avg patent value: 6.63 M
36
Incyte Corp.
Delaware, United States
Drug discovery,Medical equipment,Medicine,
...[+2]
Avg patent value: 6.63 M
37
Plexxikon, Inc.
California, United States
Health care,Medicine,Oncology drugs,
...[+2]
Avg patent value: 6.62 M
38
Achillion Pharmaceuticals, Inc.
Pennsylvania, United States
Complement system,Pharmacy and Therapeutics,Medicine,
...[+2]
Avg patent value: 6.56 M
39
Amgen, Inc.
California, United States
Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER,
...[+2]
Avg patent value: 6.53 M
40
SARcode Bioscience, Inc.
California, United States
Medicine,Health care,Ophthalmology,
...[+2]
Avg patent value: 6.46 M
41
Biogen MA, Inc.
Massachusetts, United States
Medicine,Drug,Developmental biology,
...[+2]
Avg patent value: 6.33 M
42
AbbVie, Inc.
Illinois, United States
Health care,Medicine,Biopharmaceutical,
...[+2]
Avg patent value: 6.16 M
43
Zoetis Services LLC
New Jersey, United States
Drug,Medicine,Vertical farming,
...[+2]
Avg patent value: 6.11 M
44
Alkahest, Inc.
California, United States
Alkahest,Health care,Plasma therapy,
...[+2]
Avg patent value: 6.02 M
45
Karyopharm Therapeutics, Inc.
Massachusetts, United States
Medicine,Health care,Multiple myeloma,
...[+2]
Avg patent value: 5.93 M
46
PTC Therapeutics, Inc.
New Jersey, United States
Pharmacy and Therapeutics,Medicine,Health care,
...[+2]
Avg patent value: 5.89 M
47
ImmunoGen, Inc.
Massachusetts, United States
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 5.85 M
48
Seagen Inc.
Washington, United States
Antibody-drug conjugate,Medicine,Health care,
...[+2]
Avg patent value: 5.81 M
49
Alltech, Inc.
Kentucky, United States
Physical fitness,Health care,Agriculture,
...[+2]
Avg patent value: 5.79 M
50
Pfizer Inc.
New York, United States
Health care,Clinical trial,Drug,
...[+2]
Avg patent value: 5.69 M
51
Centrexion Therapeutics Corp.
Massachusetts, United States
Medicine,Health care,Biotechnology,
...[+2]
Avg patent value: 5.67 M
52
Exelixis, Inc.
California, United States
Oncology drugs,Health care,Drug,
...[+2]
Avg patent value: 5.65 M
53
Gilead Connecticut, Inc.
Connecticut, United States
Kinase,Medicine,Health care,
...[+2]
Avg patent value: 5.63 M
54
Quince Therapeutics, Inc.
California, United States
Health care,Neurodegeneration,Animal model,
...[+2]
Avg patent value: 5.55 M
55
MEI Pharma, Inc.
California, United States
Pracinostat,Medicine,Health care,
...[+2]
Avg patent value: 5.53 M
56
Palatin Technologies, Inc.
New Jersey, United States
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 5.50 M
57
Nereus Pharmaceuticals, Inc.
California, United States
Health care,Solid tumor,Inflammation,
...[+2]
Avg patent value: 5.50 M
58
Intercept Pharmaceuticals, Inc.
New York, United States
Drug development,Medicine,Health care,
...[+2]
Avg patent value: 5.37 M
59
ArQule, Inc.
Massachusetts, United States
Pharmacy and Therapeutics,Biotechnology,Oncology drugs,
...[+2]
Avg patent value: 5.35 M
60
Lexicon Pharmaceuticals, Inc.
Texas, United States
Health care,Clinical trial,Medicine,
...[+2]
Avg patent value: 5.24 M
61
Mars, Inc.
Virginia, United States
Food products,Fast-moving consumer goods,Food industry,
...[+2]
Avg patent value: 5.21 M
62
BioCryst Pharmaceuticals, Inc.
Alabama, United States
Clinical trial,Medicine,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 5.18 M
63
Parion Sciences, Inc.
North Carolina, United States
Health care,Nebulizer,Mucus,
...[+2]
Avg patent value: 5.17 M
64
Epizyme, Inc.
Massachusetts, United States
Medicine,Health care,Biopharmaceutical,
...[+2]
Avg patent value: 5.16 M
65
Bionure Farma SL
California, United States
Clinical trial,Medical equipment,Health care,
...[+2]
Avg patent value: 5.15 M
66
Asana BioSciences LLC
New Jersey, United States
Biopharmaceutical,Medicine,Goserelin,
...[+2]
Avg patent value: 5.14 M
67
Ironwood Pharmaceuticals, Inc.
Massachusetts, United States
Medicine,Health care,Gastrointestinal agent,
...[+2]
Avg patent value: 5.13 M
68
InteKrin Therapeutics, Inc.
California, United States
Insulin,Immune disorder,Medicine,
...[+2]
Avg patent value: 5.12 M
69
PRC-DeSoto International, Inc.
California, United States
Sealant,Coating,Industrial engineering,
...[+1]
Avg patent value: 5.12 M
70
Bristol Myers Squibb Co.
New York, United States
Medicine,Health care,Oncology drugs,
...[+2]
Avg patent value: 5.11 M
71
Bristol Myers Co.
New York, United States
Botanical drug,Herb
Avg patent value: 5.11 M
72
Pfizer Products, Inc.
Connecticut, United States
Avg patent value: 5.11 M
73
Honeywell International, Inc.
North Carolina, United States
Aerospace,Electronics,Market research,
...[+2]
Avg patent value: 5.11 M
74
Bayer Pharmaceuticals Corp.
Pennsylvania, United States
Avg patent value: 5.09 M
75
Wellstat Therapeutics Corp.
United States
Drug discovery,Pharmacy,Drug development,
...[+2]
Avg patent value: 5.08 M
76
Genentech, Inc.
California, United States
Biotechnology,Biology,Medicine,
...[+2]
Avg patent value: 5.07 M
77
Arch Chemicals, Inc.
Connecticut, United States
Biocide,Chemical engineering,Coating,
...[+2]
Avg patent value: 5.05 M
78
J. M. Huber Corp.
New Jersey, United States
Health care,Ethical behavior,Sustainable forestry,
...[+2]
Avg patent value: 4.99 M
79
DowElanco Ltd.
United States
Chemical engineering,Agriculture,Pest control
Avg patent value: 4.93 M
80
Versum Materials US LLC
Pennsylvania, United States
Sanitation,SOAP
Avg patent value: 4.91 M
81
Cardioxyl Pharmaceuticals, Inc.
North Carolina, United States
Nitroxyl,Medicine,Health care,
...[+2]
Avg patent value: 4.85 M
82
Onyx Therapeutics, Inc.
California, United States
Drug,Medicine
Avg patent value: 4.80 M
83
BL Technology, Inc.
Texas, United States
Electronics,Fire alarm system,Subsea,
...[+2]
Avg patent value: 4.72 M
84
H.C. Starck, Inc.
Ohio, United States
Tantalum,Health care,Niobium,
...[+2]
Avg patent value: 4.65 M
85
Baxter International, Inc.
Illinois, United States
Clinical trial,Drug,Hemodialysis,
...[+2]
Avg patent value: 4.64 M
86
Neurocrine Biosciences, Inc.
California, United States
Endometriosis,Medicine,Health care,
...[+2]
Avg patent value: 4.64 M
87
Agios Pharmaceuticals, Inc.
Massachusetts, United States
Medicine,Health care,Biopharmaceutical,
...[+2]
Avg patent value: 4.63 M
88
Genzyme Corp.
Massachusetts, United States
Medicine,Pharmacy and Therapeutics,Multiple sclerosis,
...[+2]
Avg patent value: 4.62 M
89
Aclaris Therapeutics, Inc.
Pennsylvania, United States
Dermatology,Medicine,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 4.60 M
90
Reata Pharmaceuticals, Inc.
Texas, United States
Inflammation,Medicine,Biopharmaceutical,
...[+2]
Avg patent value: 4.59 M
91
NewGen Therapeutics, Inc.
California, United States
Pharmacy,Biotechnology,Agriculture,
...[+2]
Avg patent value: 4.58 M
92
Ignyta, Inc.
California, United States
Autoimmune disease,Biotechnology,Medicine,
...[+2]
Avg patent value: 4.55 M
93
Boehringer Ingelheim Pharmaceuticals, Inc.
Connecticut, United States
Central nervous system,Medicine,Drug,
...[+2]
Avg patent value: 4.53 M
94
Stealth BioTherapeutics, Inc.
Massachusetts, United States
Cardiovascular agent,Pharmacy and Therapeutics,Mitochondrial disease,
...[+2]
Avg patent value: 4.48 M
95
Axikin Pharmaceuticals, Inc.
California, United States
Inhaler,Biology,Medicine,
...[+2]
Avg patent value: 4.46 M
96
Auspex Pharmaceuticals, Inc.
California, United States
Medicine,Health care,Chorea,
...[+2]
Avg patent value: 4.46 M
97
CTI BioPharma Corp.
Washington, United States
Oncology,Medicine,Health care,
...[+2]
Avg patent value: 4.44 M
98
Astech, Inc.
Michigan, United States
Casting,Metal,Mining engineering,
...[+2]
Avg patent value: 4.41 M
99
Archer-Daniels-Midland Co.
Illinois, United States
Starch,Industrial engineering,Animal feed,
...[+2]
Avg patent value: 4.40 M
100
Sunovion Pharmaceuticals, Inc.
Massachusetts, United States
Medicine,Pharmacy and Therapeutics,Inhalation,
...[+2]
Avg patent value: 4.40 M

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