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Top 100 Key Players companies in Determinant
by Highest Patent Value in the world in 2018

The Determinant top 100 is Discovery PatSnap’ annual ranking of the top 100 Highest Patent Value Determinant Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2018, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
In linear algebra, the determinant is a scalar value that can be computed from the elements of a square matrix and encodes certain properties of the linear transformation described by the matrix. The determinant of a matrix A is denoted det(A), det A, or |A|. Geometrically, it can be viewed as the volume scaling factor of the linear transformation described by the matrix. This is also the signed volume of the n-dimensional parallelepiped spanned by the column or row vectors of the matrix. The determinant is positive or negative according to whether the linear mapping preserves or reverses the orientation of n-space.
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Company Name
Region
Tech Topics
Total
1
NEC Corp.
Virtualization,Big data,Network security,
...[+2]
Avg patent value: 13.76 M
2
Amgen, Inc.
Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER,
...[+2]
Avg patent value: 10.99 M
3
Kirin-Amgen, Inc.
Pharmaceutical drug,Medicine
Avg patent value: 10.99 M
4
VectorMAX Corp.
Real-time computing,Corporate communication,Educational institution,
...[+2]
Avg patent value: 8.66 M
5
Tanox Biosystems, Inc.
Immune system,Biotechnology,Agriculture,
...[+2]
Avg patent value: 8.54 M
6
Pioneer Corp.
Navigation system,Laserdisc player,Electronic product,
...[+2]
Avg patent value: 8.17 M
7
R-Pharm International, LLC
Russia
Avg patent value: 8.02 M
8
Wyeth LLC
Avg patent value: 7.56 M
9
UCB SA
Epilepsy,Adalimumab,Drug,
...[+2]
Avg patent value: 7.28 M
10
UCB Pharma, Inc.
Health care,Biopharmaceutical,Central nervous system,
...[+2]
Avg patent value: 7.28 M
11
ThermoTek, Inc.
Laser,Compression therapy,Medical equipment,
...[+2]
Avg patent value: 6.75 M
12
Molecular Templates, Inc.
Health care,Pharmacy and Therapeutics,Biopharmaceutical,
...[+2]
Avg patent value: 6.73 M
13
Dolby International AB
Information technology consulting,Systems design
Avg patent value: 6.54 M
14
Biogen International Neuroscience GmbH
ZH, CH
Neuroscience,Medicine
Avg patent value: 6.48 M
15
Pacific Edge Ltd.
Otago, New Zealand
Bladder cancer,Biology,Medicine,
...[+2]
Avg patent value: 6.37 M
16
Immatics Biotechnologies GmbH
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 5.99 M
17
UCB Biopharma SRL
Avg patent value: 5.53 M
18
ExxonMobil Chemical Patents, Inc.
Avg patent value: 5.38 M
19
UCB Pharma SA
Medicine,Chemical engineering,Epilepsy,
...[+2]
Avg patent value: 5.24 M
20
Philip Morris USA, Inc.
Smokeless tobacco,Petroleum industry,Chemical engineering,
...[+2]
Avg patent value: 5.19 M
21
MedImmune LLC
Medicine,Pharmacy and Therapeutics,Autoimmunity,
...[+2]
Avg patent value: 5.16 M
22
Qu Biologics, Inc.
Health care,Gastrointestinal agent,Biopharmaceutical,
...[+2]
Avg patent value: 4.76 M
23
Elanco Tiergesundheit AG
Medicine,Health care
Avg patent value: 4.71 M
24
Mitsubishi Tanabe Pharma Corp.
Medicine,Health care,Toxoid,
...[+2]
Avg patent value: 4.68 M
25
Regeneron Pharmaceuticals, Inc.
Monoclonal antibody,Clinical trial,Cholesterol,
...[+2]
Avg patent value: 4.67 M
26
Advanced Fusion Systems LLC
Computer hardware,Electronics,Semiconductor,
...[+1]
Avg patent value: 4.56 M
27
Netris Pharma
Dependence receptor,Biology,Health care,
...[+2]
Avg patent value: 4.43 M
28
W.R. Grace & Co.
Coating,Computer hardware,Petrochemical,
...[+2]
Avg patent value: 4.42 M
29
Danisco US, Inc.
Synthetic rubber,Bioplastic,Plasticizer,
...[+2]
Avg patent value: 4.42 M
30
Microsoft Technology Licensing LLC
Franchise agreement
Avg patent value: 4.36 M
31
QUALCOMM, Inc.
Telecommunications,Wireless,Mobile device,
...[+2]
Avg patent value: 4.26 M
32
TIAX LLC
Automotive engineering,Software,Cathode material,
...[+2]
Avg patent value: 4.23 M
33
Boehringer Ingelheim Pharmaceuticals, Inc.
Central nervous system,Medicine,Drug,
...[+2]
Avg patent value: 4.23 M
34
Mesoblast, Inc.
Orthopedic disorders,Drug,Medicine,
...[+2]
Avg patent value: 4.18 M
35
Zeraim Gedera Ltd.
Agriculture
Avg patent value: 4.05 M
36
Samsung Electronics Co., Ltd.
Computer hardware,Semiconductor,Software,
...[+2]
Avg patent value: 3.85 M
37
MeMed Diagnostics Ltd.
Medicine,Health care,Antibiotics,
...[+2]
Avg patent value: 3.62 M
38
Agricultural Genetics Co. Ltd.
Agricultural biotechnology,Plant breeding
Avg patent value: 3.50 M
39
Have Our Plastic, Inc.
Avg patent value: 3.36 M
40
Amazon Technologies, Inc.
Avg patent value: 3.02 M
41
Janssen Pharmaceutica NV
Product design,Neuroscience,Health care,
...[+2]
Avg patent value: 2.98 M
42
United Biomedical, Inc.
Medicine,Coronavirus disease 2019 (COVID-19),Renal anemia,
...[+2]
Avg patent value: 2.97 M
43
United BioPharma, Inc.
Monoclonal antibody,Medicine,Omalizumab,
...[+2]
Avg patent value: 2.97 M
44
TOTO Ltd.
Bathtub,Cistern,Sink (computing),
...[+2]
Avg patent value: 2.88 M
45
Yangshengtang Co., Ltd.
ZH, CN
Medicine,Clinical trial,Mineral water,
...[+2]
Avg patent value: 2.85 M
46
Yangsheng Tang Co Ltd
Avg patent value: 2.85 M
47
MAN Truck & Bus SE
Truck,Internet of Things,Automotive engineering
Avg patent value: 2.81 M
48
MAN Truck & Bus
Truck,Public transport,Turbomachinery,
...[+2]
Avg patent value: 2.81 M
49
Alps Green Devices Co., Ltd.
Power control,Industrial engineering
Avg patent value: 2.74 M
50
BlackBerry Ltd.
Wireless,Software,Embedded system,
...[+2]
Avg patent value: 2.73 M
51
Reber Genetics Co., Ltd.
Pharmacy,Medicine
Avg patent value: 2.70 M
52
Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.
Medicine,In vitro,Diagnostic Reagent,
...[+2]
Avg patent value: 2.62 M
53
NIPPON STEEL Stainless Steel Corp.
Mill,Metal,Mining engineering,
...[+1]
Avg patent value: 2.57 M
54
DAIKIN INDUSTRIES Ltd.
Air conditioning,Refrigeration,Mechanical engineering,
...[+2]
Avg patent value: 2.55 M
55
Daikin Airconditioning France SAS
Industrial engineering,Fluorochemical industry,Air conditioning,
...[+1]
Avg patent value: 2.55 M
56
Humanigen, Inc.
Medicine,Health care,Clinical trial,
...[+2]
Avg patent value: 2.40 M
57
Nippon Chemi-Con Corp.
Capacitor,Electronic component,Sales management,
...[+2]
Avg patent value: 2.39 M
58
Cotimes Biotechnology Co. Ltd.
Antibody,Medicine,Autoimmune disease,
...[+2]
Avg patent value: 2.36 M
59
Yamaha Motor Co., Ltd.
Robotics,Industrial robot,Automotive engineering,
...[+2]
Avg patent value: 2.32 M
60
Nippon Micrometal Corp.
Solder ball,Printed electronics,Metal
Avg patent value: 2.29 M
61
Semiconductor Energy Laboratory Co., Ltd.
Semiconductor,Transistor,Semiconductor device,
...[+2]
Avg patent value: 2.28 M
62
JFE Holdings, Inc.
Materials science,Product design,Carbon steel,
...[+2]
Avg patent value: 2.21 M
63
JFE Steel Corp.
Irone,Mining engineering,Natural resource management,
...[+2]
Avg patent value: 2.21 M
64
Shin-Etsu Chemical Co., Ltd.
Silicone,Semiconductor,Chemical engineering,
...[+2]
Avg patent value: 2.15 M
65
SANYO Electric Co., Ltd.
Semiconductor,Computer hardware,Software,
...[+2]
Avg patent value: 2.15 M
66
Sanyo Denki Co., Ltd.
Electrical equipment,Servo,Electronics,
...[+2]
Avg patent value: 2.15 M
67
Genzyme Corp.
Medicine,Pharmacy and Therapeutics,Multiple sclerosis,
...[+2]
Avg patent value: 2.13 M
68
Eisai R&D Management Co., Ltd.
Biotechnology,Agriculture,Fishery,
...[+2]
Avg patent value: 2.06 M
69
DiNonA, Inc.
Diagnostic Reagent,Medicine,Cell signaling,
...[+2]
Avg patent value: 2.03 M
70
ImNate SARL
Luxembourg, Luxembourg
Avg patent value: 1.88 M
71
Bavarian Nordic A/S
Hovedstaden, Denmark
Cancer immunotherapy,Health care,Medicine,
...[+2]
Avg patent value: 1.80 M
72
Bavarian Nordic, Inc.
Drug,Medicine
Avg patent value: 1.80 M
73
Xiaomi Corp.
Mobile device,Wearable technology,Network router,
...[+2]
Avg patent value: 1.70 M
74
Xiaomi, Inc.
Internet television,Telecommunications,Software,
...[+2]
Avg patent value: 1.70 M
75
PHC Holdings Corp.
Medical equipment,Health care,Hospitality industry,
...[+2]
Avg patent value: 1.61 M
76
Apple, Inc.
Software,Computer hardware,Peripheral,
...[+2]
Avg patent value: 1.58 M
77
Novartis AG
Dosage form,Health care,Medicine,
...[+2]
Avg patent value: 1.56 M
78
Tokyo Electron Ltd.
Semiconductor,Power transmission,Flat panel display,
...[+2]
Avg patent value: 1.55 M
79
Sandvik Mining & Construction Oy
Pirkanmaa, Finland
Metal,Automation,Manufacturing engineering,
...[+2]
Avg patent value: 1.53 M
80
Ricoh Co., Ltd.
Digital media,Data visualization,Thermal paper,
...[+2]
Avg patent value: 1.40 M
81
Beckman Coulter, Inc.
Medical equipment,Hematology,Urinalysis,
...[+2]
Avg patent value: 1.40 M
82
Beckman Instruments, Inc.
Medicine,Guidance system
Avg patent value: 1.40 M
83
LG Chem Ltd.
Petrochemical,Synthetic rubber,Health care,
...[+2]
Avg patent value: 1.32 M
84
Ventana Medical Systems, Inc.
Medical equipment,Health care,Digital pathology,
...[+2]
Avg patent value: 1.32 M
85
Immundiagnostik AG
Health care,Scientific organization,Business relations,
...[+2]
Avg patent value: 1.26 M
86
Cross Technology Solutions AB
eHealth,Health care,Hospitality industry,
...[+1]
Avg patent value: 1.26 M
87
UAB Research Foundation
Biotechnology,Agriculture,Fishery,
...[+2]
Avg patent value: 1.20 M
88
Ericsson, Inc.
Wireless,Telecommunications,Transmitter,
...[+2]
Avg patent value: 1.14 M
89
Mor Research Applications Ltd.
Gastrointestinal agent,Immunotherapy,Clinical trial,
...[+2]
Avg patent value: 1.10 M
90
Technion Research & Development Foundation Ltd.
Business entity,Oncogene,Research proposal,
...[+2]
Avg patent value: 1.10 M
91
Sony Group Corp.
Computer hardware,Software,Music,
...[+2]
Avg patent value: 1.09 M
92
Panasonic Intellectual Property Corporation of America
Electronics,Intellectual property
Avg patent value: 1.08 M
93
Toyota Motor Corp.
Sport utility vehicle,Mobile device,Public transport,
...[+2]
Avg patent value: 1.05 M
94
Hyundai Motor Co., Ltd.
Public transport,Automotive engineering,Truck,
...[+2]
Avg patent value: 1.02 M
95
Nihon Denso KK
Manufacturing engineering,Mechanical engineering
Avg patent value: 969,333
96
TLV Co. Ltd.
Control valves,Energy management
Avg patent value: 910,000
97
Koninklijke Philips NV
Health care,Wellness Programs,Medical imaging,
...[+2]
Avg patent value: 905,166
98
Elanco US, Inc.
Health care,Animal welfare,Drug,
...[+1]
Avg patent value: 900,000
99
Teijin Ltd.
Synthetic rubber,Chemical engineering,Polycarbonate,
...[+2]
Avg patent value: 870,000
100
Panasonic Holdings Corp.
Semiconductor,Industrial engineering,Electronics,
...[+2]
Avg patent value: 840,000
Page generation time: Jun 21 2025