Top 100 Key Players companies in Determinant by Highest Patent Value in the United States in 2022 – Discovery

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The Determinant top 100 is Discovery PatSnap’ annual ranking of the top 100 Highest Patent Value Determinant Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2022, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

In linear algebra, the determinant is a scalar value that can be computed from the elements of a square matrix and encodes certain properties of the linear transformation described by the matrix. The determinant of a matrix A is denoted det(A), det A, or |A|. Geometrically, it can be viewed as the volume scaling factor of the linear transformation described by the matrix. This is also the signed volume of the n-dimensional parallelepiped spanned by the column or row vectors of the matrix. The determinant is positive or negative according to whether the linear mapping preserves or reverses the orientation of n-space.

1	Amgen, Inc.	California, United States	Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER, ...[+2]	Avg patent value: 10.99 M
2	Kirin-Amgen, Inc.	California, United States	Pharmaceutical drug,Medicine	Avg patent value: 10.99 M
3	VectorMAX Corp.	New York, United States	Real-time computing,Corporate communication,Educational institution, ...[+2]	Avg patent value: 8.66 M
4	Tanox Biosystems, Inc.	Texas, United States	Immune system,Biotechnology,Agriculture, ...[+2]	Avg patent value: 8.54 M
5	Wyeth LLC	New Jersey, United States		Avg patent value: 7.56 M
6	ThermoTek, Inc.	Texas, United States	Laser,Compression therapy,Medical equipment, ...[+2]	Avg patent value: 6.75 M
7	Molecular Templates, Inc.	Texas, United States	Health care,Pharmacy and Therapeutics,Biopharmaceutical, ...[+2]	Avg patent value: 6.73 M
8	ExxonMobil Chemical Patents, Inc.	United States		Avg patent value: 5.38 M
9	Philip Morris USA, Inc.	Virginia, United States	Smokeless tobacco,Petroleum industry,Chemical engineering, ...[+2]	Avg patent value: 5.19 M
10	MedImmune LLC	Louisiana, United States	Medicine,Pharmacy and Therapeutics,Autoimmunity, ...[+2]	Avg patent value: 5.16 M
11	Regeneron Pharmaceuticals, Inc.	New York, United States	Monoclonal antibody,Clinical trial,Cholesterol, ...[+2]	Avg patent value: 4.67 M
12	Advanced Fusion Systems LLC	New York, United States	Computer hardware,Electronics,Semiconductor, ...[+1]	Avg patent value: 4.56 M
13	W.R. Grace & Co.	United States	Coating,Computer hardware,Petrochemical, ...[+2]	Avg patent value: 4.42 M
14	Danisco US, Inc.	Delaware, United States	Synthetic rubber,Bioplastic,Plasticizer, ...[+2]	Avg patent value: 4.42 M
15	Microsoft Technology Licensing LLC	Washington, United States	Franchise agreement	Avg patent value: 4.36 M
16	QUALCOMM, Inc.	California, United States	Telecommunications,Wireless,Mobile device, ...[+2]	Avg patent value: 4.26 M
17	TIAX LLC	Massachusetts, United States	Automotive engineering,Software,Cathode material, ...[+2]	Avg patent value: 4.23 M
18	Boehringer Ingelheim Pharmaceuticals, Inc.	Connecticut, United States	Central nervous system,Medicine,Drug, ...[+2]	Avg patent value: 4.23 M
19	Mesoblast, Inc.	New York, United States	Orthopedic disorders,Drug,Medicine, ...[+2]	Avg patent value: 4.18 M
20	Amazon Technologies, Inc.	Nevada, United States		Avg patent value: 3.02 M
21	United Biomedical, Inc.	New York, United States	Medicine,Coronavirus disease 2019 (COVID-19),Renal anemia, ...[+2]	Avg patent value: 2.97 M
22	Humanigen, Inc.	California, United States	Medicine,Health care,Clinical trial, ...[+2]	Avg patent value: 2.40 M
23	Genzyme Corp.	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,Multiple sclerosis, ...[+2]	Avg patent value: 2.13 M
24	Bavarian Nordic, Inc.	North Carolina, United States	Drug,Medicine	Avg patent value: 1.80 M
25	Apple, Inc.	California, United States	Software,Computer hardware,Peripheral, ...[+2]	Avg patent value: 1.58 M
26	Beckman Coulter, Inc.	California, United States	Medical equipment,Hematology,Urinalysis, ...[+2]	Avg patent value: 1.40 M
27	Beckman Instruments, Inc.	Indiana, United States	Medicine,Guidance system	Avg patent value: 1.40 M
28	Ventana Medical Systems, Inc.	Arizona, United States	Medical equipment,Health care,Digital pathology, ...[+2]	Avg patent value: 1.32 M
29	UAB Research Foundation	Alabama, United States	Biotechnology,Agriculture,Fishery, ...[+2]	Avg patent value: 1.20 M
30	Ericsson, Inc.	Texas, United States	Wireless,Telecommunications,Transmitter, ...[+2]	Avg patent value: 1.14 M
31	Panasonic Intellectual Property Corporation of America	California, United States	Electronics,Intellectual property	Avg patent value: 1.08 M
32	Elanco US, Inc.	Indiana, United States	Health care,Animal welfare,Drug, ...[+1]	Avg patent value: 900,000
33	Monogram Biosciences, Inc.	California, United States	Health care,Microbiology Test,Coronavirus, ...[+2]	Avg patent value: 840,000
34	Roku, Inc.	California, United States	Advertising,Computer hardware,Cable television, ...[+2]	Avg patent value: 740,000
35	TriPath Imaging, Inc.	North Carolina, United States	Cervical cytology screening,Medicine,Health care, ...[+2]	Avg patent value: 460,000
36	Intel Corp.	California, United States	Semiconductor,Software,Computer hardware, ...[+2]	Avg patent value: 438,250
37	Cummins, Inc.	Indiana, United States	Electric vehicle,Natural gas,Petroleum industry, ...[+2]	Avg patent value: 420,000
38	Adobe, Inc.	California, United States	Software,Enterprise software,Computer vision, ...[+2]	Avg patent value: 400,000
39	Citrix Systems, Inc.	Florida, United States	Virtualization,Software as a service,Enterprise software, ...[+2]	Avg patent value: 360,000
40	Immutrix Therapeutics, Inc.	South Dakota, United States	Medical equipment,Health care,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 340,000
41	Fujitsu Microelectronics America, Inc.	California, United States	Semiconductor,Microelectronics,Electronic component, ...[+2]	Avg patent value: 316,666
42	DowElanco Ltd.	United States	Chemical engineering,Agriculture,Pest control	Avg patent value: 250,000
43	General Electric Co.	Massachusetts, United States	Energy management,Turbine,Electronics, ...[+2]	Avg patent value: 180,000
44	3M Innovative Properties Co.	Minnesota, United States	Intellectual property,Product design	Avg patent value: 145,000
45	Covidien LP	Massachusetts, United States	Analgesic,Medicine,Medical equipment, ...[+1]	Avg patent value: 130,000
46	Sanaria, Inc.	United States	Biology,Health care,Plasmodium falciparum, ...[+2]	Avg patent value: 120,000
47	Honeywell International, Inc.	North Carolina, United States	Aerospace,Electronics,Market research, ...[+2]	Avg patent value: 110,000
48	CAMX Power LLC	Massachusetts, United States	Lithium-ion battery,CAMX,Electronics, ...[+2]	Avg patent value: 110,000
49	The Broad Institute, Inc.	Massachusetts, United States	Clinical trial,Biology,Genomics, ...[+2]	Avg patent value: 100,000
50	Genentech, Inc.	California, United States	Biotechnology,Biology,Medicine, ...[+2]	Avg patent value: 97,000
51	TechnoImaging LLC	Utah, United States	Salt lake,Software,Health care	Avg patent value: 84,000
52	Keysight Technologies, Inc.	California, United States	Electronics,Power transmission,Measurement science, ...[+2]	Avg patent value: 77,000
53	Geron Corp.	California, United States	Medicine,Telomerase Inhibitor,Imetelstat, ...[+2]	Avg patent value: 74,000
54	Proteovista LLC	Wisconsin, United States	DNA,Proteome,Proteomics, ...[+2]	Avg patent value: 71,000
55	Electronic Systems Protection, Inc.	North Carolina, United States	Supply energy,Automation,Manufacturing engineering, ...[+2]	Avg patent value: 69,000
56	United Services Automobile Association	Texas, United States	Insurance carriers,Venture capital,Army officer, ...[+2]	Avg patent value: 68,666
57	Block, Inc.	California, United States	Mobile payment,Software,Computer hardware, ...[+2]	Avg patent value: 68,000
58	Actelis Networks, Inc.	California, United States	Telecommunications,Wireless,Ethernet, ...[+2]	Avg patent value: 68,000
59	Arcellx, Inc.	United States	Medicine,Cell therapy,Cell, ...[+2]	Avg patent value: 67,000
60	Hewlett Packard Enterprise Development LP	Texas, United States	Information technology consulting,Systems design,Computer security, ...[+2]	Avg patent value: 66,000
61	Sanofi Pasteur Biologics LLC	Massachusetts, United States	Medicine	Avg patent value: 57,000
62	Konami Gaming, Inc.	Nevada, United States	Lottery,Betaine,Management system, ...[+1]	Avg patent value: 44,000
63	Givaudan Fragrances Corp.	New Jersey, United States	Cosmetics	Avg patent value: 37,000
64	Robert Bosch Corp.	Michigan, United States	Shopping mall,Truck	Avg patent value: 36,933
65	The Boeing Co.	Illinois, United States	Aerospace,Satellite,National security, ...[+2]	Avg patent value: 31,000
66	Coast Hotels & Casinos, Inc.	Nevada, United States	Leisure satisfaction	Avg patent value: 16,000
67	ArmadaHealth LLC	United States		Avg patent value: 16,000
68	Raytheon Co.	Massachusetts, United States	Missile,National security,Aerospace, ...[+2]	Avg patent value: 13,000
69	Capital One Services LLC	Virginia, United States	Financial instrument,Electronic funds transfer,Financial transaction	Avg patent value: 4,100
70	Penumbra, Inc.	California, United States	Medical equipment,Penumbra,Neuroradiology, ...[+2]	Avg patent value: 4,000
71	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	Avg patent value: 3,900
72	Merck Sharp & Dohme Corp.	New Jersey, United States	Prescription drug,Medicine,Stroke, ...[+2]	Avg patent value: 3,900
73	Caterpillar, Inc.	Illinois, United States	Turbine,Construction engineering,Mechanical engineering, ...[+2]	Avg patent value: 0
74	Halliburton Co.	Texas, United States	Artificial lift,Natural resource management,Renewable energy, ...[+2]	Avg patent value: 0
75	Eli Lilly & Co.	Indiana, United States	Medicine,Health care,Humalog Mix, ...[+2]	Avg patent value: 0
76	Repligen Corp.	Massachusetts, United States	Chromatography,Fast-moving consumer goods,Protein A, ...[+2]	Avg patent value: 0
77	Google LLC	California, United States	Advertising,Enterprise software,Search engine, ...[+2]	Avg patent value: 0
78	Nuance Communications, Inc.	Massachusetts, United States	Software,Artificial intelligence,Enterprise software, ...[+2]	Avg patent value: 0
79	Agenus, Inc.	Massachusetts, United States	Medical equipment,Pharmacy and Therapeutics,Antibody, ...[+2]	Avg patent value: 0
80	Cypress Semiconductor Corp.	California, United States	Semiconductor,Product design,Industrial engineering, ...[+2]	Avg patent value: 0
81	Sikorsky Aircraft Corp.	Connecticut, United States	Aerospace,National security,Spare part, ...[+2]	Avg patent value: 0
82	Cytel, Inc.	Massachusetts, United States	Clinical trial,Software,Optimal design, ...[+2]	Avg patent value: 0
83	Motorola Mobility LLC	Illinois, United States	Mobile device,Telecommunications,Headphones, ...[+2]	Avg patent value: 0
84	Abgenix, Inc.	California, United States	Antibody,Pharmacy and Therapeutics,Lead compound, ...[+2]	Avg patent value: 0
85	Roche Diagnostics Corp.	Indiana, United States	Medicine,Urinalysis,Immunoassay, ...[+2]	Avg patent value: 0
86	Metamark Genetics, Inc.	Massachusetts, United States	Health care,Diagnostic test,Cancer, ...[+2]	Avg patent value: 0
87	Quid, Inc.	California, United States	Software,Natural language processing,Artificial intelligence, ...[+2]	Avg patent value: 0
88	Aphton Corp.	Pennsylvania, United States	Biopharmaceutical,Medicine	Avg patent value: 0
89	Pioneer Hi-Bred International, Inc.	Iowa, United States		Avg patent value: 0
90	Epimmune, Inc.	California, United States	Botanical drug,Herb	Avg patent value: 0
91	The General Hospital Corp.	Massachusetts, United States	Health care,Hospitality industry,Vascular Medicine, ...[+2]	Avg patent value: 0
92	IDEC Pharmaceuticals Corp.	California, United States	Autoimmune disease,Health care,Apomorphine, ...[+2]	Avg patent value: 0
93	Perosphere, Inc.	Connecticut, United States	Anticoagulant,Drug,Health care, ...[+2]	Avg patent value: 0
94	String Labs, Inc.	California, United States	Incubator,Systems design,Blockchain, ...[+1]	Avg patent value: 0
95	Bristol Myers Co.	New York, United States	Botanical drug,Herb	Avg patent value: 0
96	Theraclone Sciences, Inc.	Washington, United States	Monoclonal antibody,Health care,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 0
97	Agere Systems LLC	Texas, United States	Semiconductor,Network processor,Vertical-cavity surface-emitting laser, ...[+2]	Avg patent value: 0
98	Chiron Diagnostics Corp.	Massachusetts, United States	Medicine	Avg patent value: 0
99	Cylex, Inc.	North Carolina, United States	In vitro,Medicine,Botanical drug, ...[+2]	Avg patent value: 0
100	Syngenta Crop Protection LLC	North Carolina, United States	Pesticide,Fungicide,Agriculture, ...[+2]	Avg patent value: 0