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Top 100 Key Players companies in Determinant
by Most Patent Filings in the United States in 2022

The Determinant top 100 is Discovery PatSnap’ annual ranking of the top 100 Most Patent Filings Determinant Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2022, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
In linear algebra, the determinant is a scalar value that can be computed from the elements of a square matrix and encodes certain properties of the linear transformation described by the matrix. The determinant of a matrix A is denoted det(A), det A, or |A|. Geometrically, it can be viewed as the volume scaling factor of the linear transformation described by the matrix. This is also the signed volume of the n-dimensional parallelepiped spanned by the column or row vectors of the matrix. The determinant is positive or negative according to whether the linear mapping preserves or reverses the orientation of n-space.
#
Company Name
Region
Tech Topics
Total
1
Patent: 46
2
Patent: 39
3
Health care,Biopharmaceutical,Drug,
...[+2]
Patent: 34
4
Patent: 34
5
Patent: 27
6
Patent: 25
7
Patent: 19
8
Patent: 19
9
Substance abuse,Hospitality industry,Health care,
...[+2]
Patent: 17
10
Health care,Hospitality industry,Vascular Medicine,
...[+2]
Patent: 17
11
Patent: 16
12
Patent: 15
13
Aerospace,Satellite,National security,
...[+2]
Patent: 14
14
Patent: 14
15
Patent: 14
16
Patent: 14
17
Medicine,Pharmacy and Therapeutics,Multiple sclerosis,
...[+2]
Patent: 13
18
Medicine,Pharmacy and Therapeutics,Autoimmunity,
...[+2]
Patent: 13
19
Medical research,Critical area,Battlefield,
...[+1]
Patent: 13
20
Asset management
Patent: 13
21
Physical science,Mobile device,Gene delivery,
...[+2]
Patent: 12
22
Patent: 12
23
Patent: 11
24
Patent: 11
25
Autoimmune disease,Health care,Apomorphine,
...[+2]
Patent: 10
26
Medicine,Health care,Oncology drugs,
...[+2]
Patent: 9
27
Patent: 9
28
Health care,Oncology,Recurrent Ovarian Cancer,
...[+2]
Patent: 9
29
Patent: 9
30
Patent: 9
31
Patent: 9
32
Patent: 9
33
Patent: 8
34
Patent: 8
35
Patent: 8
36
Patent: 8
37
Franchise agreement
Patent: 8
38
Patent: 8
39
Patent: 7
40
Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER,
...[+2]
Patent: 7
41
Patent: 7
42
Patent: 7
43
Patent: 7
44
Medical equipment,Health care,Pharmacy and Therapeutics,
...[+2]
Patent: 7
45
Patent: 7
46
Shopping mall,Truck
Patent: 7
47
Patent: 6
48
Health care,Medical equipment,Risperidone,
...[+2]
Patent: 6
49
Medicine,Health care,Humalog Mix,
...[+2]
Patent: 6
50
Patent: 6
51
Medicine,Telomerase Inhibitor,Imetelstat,
...[+2]
Patent: 6
52
Medicine,Health care,Microarray method,
...[+2]
Patent: 6
53
Patent: 6
54
Patent: 6
55
Patent: 6
56
Patent: 6
57
Monoclonal antibody,Health care,Pharmacy and Therapeutics,
...[+2]
Patent: 6
58
Social web,Publishing,Voice over IP,
...[+2]
Patent: 6
59
Patent: 5
60
Patent: 5
61
Pharmacy and Therapeutics,Medical equipment,Biopharmaceutical,
...[+2]
Patent: 5
62
Patent: 5
63
Patent: 5
64
Patent: 5
65
Biomedical Frontiers, Inc.
Patent: 5
66
Patent: 4
67
Patent: 4
68
3D printing,Photography,Digital media,
...[+2]
Patent: 4
69
Patent: 4
70
Aerospace,National security,Spare part,
...[+2]
Patent: 4
71
Medicine,Health care,Clinical trial,
...[+2]
Patent: 4
72
Health care,Microbiology Test,Coronavirus,
...[+2]
Patent: 4
73
Pharmacy and Therapeutics,Hepatitis C virus,Medicine,
...[+2]
Patent: 4
74
Biology,Health care,Plasmodium falciparum,
...[+2]
Patent: 4
75
Oncogene,Health care,Birth control,
...[+2]
Patent: 4
76
Patent: 4
77
Alternative investment,Asset management,Venture capital
Patent: 4
78
Patent: 4
79
Patent: 4
80
Patent: 3
81
Patent: 3
82
Patent: 3
83
Chromatography,Fast-moving consumer goods,Protein A,
...[+2]
Patent: 3
84
Insurance carriers,Venture capital,Army officer,
...[+2]
Patent: 3
85
Missile,National security,Aerospace,
...[+2]
Patent: 3
86
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Patent: 3
87
Patent: 3
88
Patent: 3
89
Patent: 3
90
Public university
Patent: 3
91
Patent: 3
92
Patent: 3
93
Patent: 3
94
Patent: 3
95
Patent: 3
96
Patent: 3
97
Patent: 3
98
ArmadaHealth LLC
Patent: 3
99
Patent: 3
100
Patent: 3
Page generation time: May 14 2025