Top 100 Key Players companies in Levodopa by Highest Patent Value in the world in 2022 – Discovery

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The Levodopa top 100 is Discovery PatSnap’ annual ranking of the top 100 Highest Patent Value Levodopa Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2022, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

l-DOPA, also known as levodopa and l-3,4-dihydroxyphenylalanine, is an amino acid that is made and used as part of the normal biology of humans, as well as some animals and plants. Humans, as well as a portion of the other animals that utilize l-DOPA in their biology, make it via biosynthesis from the amino acid l-tyrosine. l-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), which are collectively known as catecholamines. Furthermore, l-DOPA itself mediates neurotrophic factor release by the brain and CNS. l-DOPA can be manufactured and in its pure form is sold as a psychoactive drug with the INN levodopa; trade names include Sinemet, Pharmacopa, Atamet, Stalevo, Madopar, and Prolopa. As a drug, it is used in the clinical treatment of Parkinson's disease and dopamine-responsive dystonia.

1	ACADIA Pharmaceuticals, Inc.	California, United States	Medicine,Health care,Psychosis, ...[+2]	Avg patent value: 8.76 M
2	Schering Corp.	New Jersey, United States	Hepatitis,Medicine,Allergy	Avg patent value: 8.21 M
3	Newron Pharmaceuticals SpA	Lombardia, Italy	Safinamide,Health care,Levodopa, ...[+2]	Avg patent value: 8.14 M
4	Kyowa Kirin Co., Ltd.	Tokyo, Japan	Health care,Drug,Medicine, ...[+2]	Avg patent value: 6.90 M
5	VistaGen Therapeutics, Inc.	California, United States	Medicine,Clinical trial,Biopharmaceutical, ...[+2]	Avg patent value: 6.71 M
6	Impax Laboratories LLC	California, United States	Pharmaceutical market,Medicine,Levodopa, ...[+2]	Avg patent value: 6.52 M
7	Alkermes, Inc.	DUBLIN, Ireland	Medicine,Health care,Liposome, ...[+2]	Avg patent value: 6.48 M
8	AbbVie, Inc.	Illinois, United States	Health care,Medicine,Biopharmaceutical, ...[+2]	Avg patent value: 5.84 M
9	NeuroDerm Ltd.	HaMerkaz, Israel	Central nervous system,Health care,Clinical efficacy, ...[+2]	Avg patent value: 5.64 M
10	Pharma Two B Ltd.	HaMerkaz, Israel	Drug,Medicine,Apomorphine, ...[+2]	Avg patent value: 5.58 M
11	Kyowa Hakko Kogyo Co., Ltd.	Tokyo, Japan	Fertilizer,Agrochemical,Raw material, ...[+2]	Avg patent value: 5.57 M
12	NuPathe, Inc.	Pennsylvania, United States	Medicine,Health care,Continuous delivery, ...[+2]	Avg patent value: 5.47 M
13	Kissei Pharmaceutical Co., Ltd.	Nagano, Japan	Food industry,Agriculture,Endocrinology, ...[+2]	Avg patent value: 5.19 M
14	BIAL-Portela & Cia SA	Porto, Portugal	Eslicarbazepine acetate,Medicine,Health care, ...[+2]	Avg patent value: 4.54 M
15	Rijk Zwaan Zaadteelt en Zaadhandel BV	Zuid-Holland, Netherlands	Hybrid seed,Food industry,Cottonseed, ...[+2]	Avg patent value: 4.37 M
16	Biotie Therapies GmbH	Germany	Biotechnology,Agriculture,Fishery, ...[+2]	Avg patent value: 4.32 M
17	Novartis AG	Basel-Stadt, Switzerland	Dosage form,Health care,Medicine, ...[+2]	Avg patent value: 4.31 M
18	Omeros Corp.	Washington, United States	Medicine,Health care,Central nervous system, ...[+2]	Avg patent value: 4.29 M
19	Lobsor Pharmaceuticals AB	Sweden	Neurology,Drug,Medicine	Avg patent value: 4.23 M
20	Civitas Therapeutics, Inc.	Massachusetts, United States	Levodopa,Biology,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 4.15 M
21	Denali Therapeutics, Inc.	California, United States	Biotechnology,Pharmacy and Therapeutics,Biological process, ...[+2]	Avg patent value: 3.43 M
22	Intec Pharma Ltd.	Jerusalem, Israel	Health care,Pill,Drug, ...[+2]	Avg patent value: 3.27 M
23	Dizlin Medical Design AB	Sweden	Medicine	Avg patent value: 3.24 M
24	Otsuka Pharmaceutical Co., Ltd.	Tokyo, Japan	Nutraceutical,Health care,Cosmetics, ...[+2]	Avg patent value: 3.18 M
25	IRLAB Therapeutics AB	Västra Götaland, Sweden	Drug discovery,Medicine,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 3.04 M
26	Merck Sharp & Dohme Corp.	New Jersey, United States	Prescription drug,Medicine,Stroke, ...[+2]	Avg patent value: 2.95 M
27	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	Avg patent value: 2.91 M
28	Neurocrine Biosciences, Inc.	California, United States	Endometriosis,Medicine,Health care, ...[+2]	Avg patent value: 2.61 M
29	Takeda Pharmaceutical Co., Ltd.	Osaka, Japan	Medicine,Health care,Clinical trial, ...[+2]	Avg patent value: 2.37 M
30	Takeda Chemical Industries Ltd.	Japan	Pharmaceutical drug,Botanical drug,Herb	Avg patent value: 2.37 M
31	Orion Co., Ltd.	Tokyo, Japan	Computer graphics,Software as a service,Enterprise software, ...[+2]	Avg patent value: 2.18 M
32	Institut National de la Santé et de la Recherche Médicale	Île-de-France, France	Public health,Genomics,Antisense therapy, ...[+2]	Avg patent value: 2.07 M
33	STARTUP INSERM Limoges		E-commerce	Avg patent value: 2.07 M
34	GIE LVMH Recherche	France	Lotion	Avg patent value: 2.07 M
35	AbbVie Pharmaceuticals GmbH	Germany	Medicine	Avg patent value: 2.00 M
36	LTS LOHMANN Therapie-Systeme AG	Rheinland-Pfalz, Germany	Transdermal patch,Health care,Micro array, ...[+2]	Avg patent value: 1.95 M
37	Ono Pharmaceutical Co., Ltd.	Osaka, Japan	Diagnostic Reagent,Medicine,Health care, ...[+2]	Avg patent value: 1.79 M
38	LG Chem Ltd.	South Korea	Petrochemical,Synthetic rubber,Health care, ...[+2]	Avg patent value: 1.77 M
39	Shanjin Optoelectronics (Suzhou) Co. Ltd.	China		Avg patent value: 1.77 M
40	STARTUP Prexton Therapeutics SA	Genève, Switzerland	Health care,Apomorphine,Safinamide, ...[+1]	Avg patent value: 1.62 M
41	Laboratorio Medinfar Produtos Farmaceuticos SA	Lisboa, Portugal	Herb,Botanical drug,Antibiotics, ...[+2]	Avg patent value: 1.49 M
42	Lusomedicamenta	Lisboa, Portugal	Quality standard,Health care	Avg patent value: 1.49 M
43	Contera Pharma ApS	Hovedstaden, Denmark	Medicine,Health care,Apomorphine, ...[+2]	Avg patent value: 1.40 M
44	Assertio Therapeutics, Inc.	Illinois, United States	Analgesic,Biology,Medicine, ...[+2]	Avg patent value: 1.35 M
45	TransForm Pharmaceuticals, Inc.	Massachusetts, United States	Drug molecule,Health care,Medicine, ...[+2]	Avg patent value: 1.24 M
46	InnoPharmax, Inc.	Taiwan Province, China	Pharmacy,Medicine,Drug development, ...[+2]	Avg patent value: 1.16 M
47	Janssen Biotech, Inc.	Pennsylvania, United States	Medicine,Health care,Biotechnology, ...[+2]	Avg patent value: 1.11 M
48	Lundbeck NA Ltd.	New York, United States		Avg patent value: 650,000
49	Doshisha Co., Ltd.	Osaka, Japan	Electronics,Product planning,National brand, ...[+2]	Avg patent value: 620,000
50	National Center For Geriatrics & Gerontology	Japan		Avg patent value: 620,000
51	Dizlin Pharmaceuticals AB	Kalmar, Sweden		Avg patent value: 613,927
52	KOREA UNITED PHARM, Inc.	South Korea	Pharmaceutical drug,Medicine,Health care	Avg patent value: 602,000
53	Wockhardt Ltd.	Maharashtra, India	Pharmacy,Insulin,Biopharmaceutical, ...[+2]	Avg patent value: 362,555
54	Psychogenics, Inc.	New Jersey, United States	Medicine,Health care,Microdialysis, ...[+2]	Avg patent value: 320,000
55	Oxford Biomedica (UK) Ltd.	Oxfordshire, United Kingdom	Cell therapy,Pharmacy and Therapeutics,Gene, ...[+2]	Avg patent value: 310,000
56	Prilenia Therapeutics Development Ltd.	Tel Aviv, Israel	Neurodevelopmental disorder	Avg patent value: 283,983
57	Adamas Pharmaceuticals, Inc.	California, United States	Medicine,Health care,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 240,000
58	Andaman Therapeutics, Inc.	California, United States	Health care	Avg patent value: 240,000
59	Jiangyin Berryson Biochemical Technology Co., Ltd.	Jiangsu Sheng, China		Avg patent value: 235,000
60	XenoPort, Inc.	California, United States	Software development,Gabapentin enacarbil,Neurological disorder, ...[+2]	Avg patent value: 175,000
61	AbbVie BV	Netherlands	Medicine	Avg patent value: 150,000
62	Wyeth LLC	New Jersey, United States		Avg patent value: 130,000
63	OmniActive Health Technologies Ltd.	New Jersey, United States	Health care,Curcumin,Feed additive, ...[+2]	Avg patent value: 120,000
64	Yeda Research & Development Co. Ltd.	HaMerkaz, Israel	Association (object-oriented programming),Intellectual property,Biotechnology, ...[+2]	Avg patent value: 120,000
65	Mylan, Inc.	Pennsylvania, United States	Biology,Medicine,Health care, ...[+2]	Avg patent value: 110,000
66	Mylan Laboratories, Inc.	Pennsylvania, United States	Health care,Repaglinide,Risedronate Sodium, ...[+2]	Avg patent value: 110,000
67	GL Biochem (Shanghai) Ltd.	Shanghai Shi, China	Biocompatible material,Peptide,Medicine, ...[+1]	Avg patent value: 110,000
68	Eisai R&D Management Co., Ltd.	Tokyo, Japan	Biotechnology,Agriculture,Fishery, ...[+2]	Avg patent value: 100,000
69	Boston Scientific Neuromodulation Corp.	California, United States	Neuromodulation,Management information systems,Health care	Avg patent value: 99,000
70	Beijing CoSci Med-Tech Co., Ltd.	Beijing Shi, China	Medicine,Drug development,Drug, ...[+2]	Avg patent value: 92,000
71	Teva Pharmaceutical Industries Ltd.	HaMerkaz, Israel	Health care,Human immunodeficiency,Drug, ...[+2]	Avg patent value: 84,000
72	Teva Pharmaceuticals International GmbH	Switzerland		Avg patent value: 81,333
73	Regents of the University of California	California, United States	Working capital,Pathology,Companion diagnostic, ...[+2]	Avg patent value: 81,000
74	Schwarz Pharma Sl	Spain		Avg patent value: 73,000
75	EuroEspes SA	Spain	Central nervous system,Health care,Hospitality industry	Avg patent value: 71,000
76	Warner Babcock Institute For Green Chemistry LLC	Massachusetts, United States	Green chemistry,Chemical engineering,Sustainable design, ...[+1]	Avg patent value: 70,000
77	Clera Inc.	Ontario, Canada	Drug discovery,Parkinson's disease,Drug development, ...[+2]	Avg patent value: 65,000
78	Phytrix, Inc.	US		Avg patent value: 63,000
79	NeuroHealing Pharmaceuticals, Inc.	Massachusetts, United States	Premature ejaculation,Medicine,Apomorphine, ...[+2]	Avg patent value: 57,000
80	Perfect (China) Co., Ltd.	Guangdong Sheng, China	Customer insight,Food industry,Skin care, ...[+2]	Avg patent value: 56,000
81	Nutricia NV	Zuid-Holland, Netherlands	Food industry	Avg patent value: 56,000
82	Yangzhou Perfect Daily Necessities Co., Ltd.	Jiangsu Sheng, China		Avg patent value: 56,000
83	Otsuka America Pharmaceutical, Inc.	United States	Neuroscience,Medicine,Drug, ...[+2]	Avg patent value: 55,000
84	Lucas Meyer Cosmetics SAS	Ile-de-France, France	Cosmetics,Active ingredient,Phospholipid, ...[+1]	Avg patent value: 54,000
85	Versi Group LLC	United States		Avg patent value: 51,000
86	Ohara Pharmaceutical Co., Ltd.	Shiga, Japan	Orphan drug,Food additive,Stem cell, ...[+2]	Avg patent value: 50,000
87	Changxing Pharmaceutical Co., Ltd.	Zhejiang Sheng, China	Drug,Medicine	Avg patent value: 49,100
88	Avion Pharmaceuticals LLC	United States	Market potential,Medicine,Health care, ...[+2]	Avg patent value: 49,000
89	STARTUP Ningbo Meisai Biological Engineering Co. Ltd.	Zhejiang Sheng, China	Catalysis,Enzyme	Avg patent value: 48,000
90	ABX advanced biochemical compounds GmbH	Sachsen-Anhalt, Germany	Nuclear medicine,Chemical engineering,Molecular imaging, ...[+1]	Avg patent value: 47,000
91	Solural Pharma ApS	Hovedstaden, Denmark	Drug,Oncology,Breast cancer, ...[+1]	Avg patent value: 41,000
92	Biologische Heilmittel Heel GmbH	Baden-Württemberg, Germany	Combination Medication,Medicine,Tincture (heraldry), ...[+2]	Avg patent value: 38,000
93	Sumitomo Pharma Co., Ltd.	Osaka, Japan	Medicine,Health care,Clinical trial, ...[+2]	Avg patent value: 37,262
94	Sumitomo Pharmaceuticals Co., Ltd.	Osaka, Japan	Botanical drug,Herb	Avg patent value: 37,262
95	STARTUP Myodopa Ltd.	United Kingdom	Pharmacy and Therapeutics,Biology	Avg patent value: 35,000
96	Impel Pharmaceuticals, Inc.	Washington, United States	Medical equipment,Health care,Central nervous system, ...[+2]	Avg patent value: 31,000
97	Bio-FD&C Co., Ltd.	Incheon, South Korea	Medical equipment,Medicine,Biomolecule, ...[+2]	Avg patent value: 29,000
98	Polyganics BV	Groningen, Netherlands	Medical equipment,Health care,Neurosurgery, ...[+2]	Avg patent value: 25,300
99	Gachon University Gil Medical Center	South Korea	Emergency medicine,Intensive care,Intensive care medicine, ...[+2]	Avg patent value: 24,000
100	Rottapharm Ltd.	Dublin, Ireland	Nutraceutical,Health care	Avg patent value: 24,000