Top 100 Key Players companies in Lysosome by Most News Heat in the world in 2018 – Discovery

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The Lysosome top 100 is Discovery PatSnap’ annual ranking of the top 100 Most News Heat Lysosome Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2018, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

A lysosome (/ˈlaɪsəˌsoʊm/) is a membrane-bound organelle found in many animal cells. They are spherical vesicles that contain hydrolytic enzymes that can break down many kinds of biomolecules. A lysosome has a specific composition, of both its membrane proteins, and its lumenal proteins. The lumen's pH (~4.5–5.0) is optimal for the enzymes involved in hydrolysis, analogous to the activity of the stomach. Besides degradation of polymers, the lysosome is involved in various cell processes, including secretion, plasma membrane repair, cell signaling, and energy metabolism.

1	Amicus Therapeutics, Inc.	New Jersey, United States	Pharmacological chaperone,Medicine,Health care, ...[+2]	news: 20
2	European Medicines Agency	United Kingdom	Safety monitoring,Contract research organization,Laboratory testing, ...[+2]	news: 16
3	Genzyme Corp.	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,Multiple sclerosis, ...[+2]	news: 15
4	BioMarin Pharmaceutical, Inc.	California, United States	Software development,Biopharmaceutical,Clinical trial, ...[+2]	news: 14
5	Synageva BioPharma Corp.	Massachusetts, United States	Botanical drug,Herb,Accelerated atherosclerosis, ...[+2]	news: 14
6	STARTUP Amicus	Delhi, India	Algorithm,E-commerce,Data integration, ...[+2]	news: 14
7	Alexion Pharmaceuticals, Inc.	Connecticut, United States	Health care,Biopharmaceutical,Clinical trial, ...[+2]	news: 12
8	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	news: 11
9	Synageva BioPharma	Massachusetts, United States	Protein therapeutics,Pharmacy and Therapeutics,Biopharmaceutical	news: 11
10	Merck Serono SA	Hessen, Germany	Biology,Health care,Fertility, ...[+2]	news: 9
11	Lysosomal Therapeutics, Inc.	Massachusetts, United States	Health care,Pharmacy and Therapeutics,Neurodegeneration, ...[+2]	news: 9
12	Sanofi	Île-de-France, France	Health care,Pharmacy and Therapeutics,Drug, ...[+2]	news: 8
13	Kanuma Cable Television	Tochigi, Japan	Cable television,Social network,Broadcasting	news: 8
14	Jones Lang LaSalle, Inc.	Illinois, United States	Facility management,Property (philosophy),Property management, ...[+2]	news: 6
15	Theravance Biopharma, Inc.	California, United States	Medicine,Health care,Bifunctional, ...[+2]	news: 6
16	Orphazyme A/S	Hovedstaden, Denmark	Lysosomal storage disease,Medicine,Pharmacy and Therapeutics, ...[+2]	news: 5
17	GMO Media, Inc.	Tokyo, Japan	Data processing,Wallpaper,Digital content	news: 5
18	L A L Sprachreisen GmbH	Germany	Sign language,Foreign language	news: 5
19	Alfa SAB de CV	Nuevo León, Mexico	Pastry,Chemical engineering,Food sector, ...[+2]	news: 4
20	Atlas Ventures Advisors, Inc.	Massachusetts, United States	Venture capital,Health care,Monoclonal antibody, ...[+2]	news: 4
21	Sanofi Ventures	Massachusetts, United States	Corporate venture capital,Health care,Secondary progressive multiple sclerosis, ...[+2]	news: 4
22	Pure Communications LLC	North Carolina, United States		news: 4
23	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	news: 3
24	Gilead Sciences, Inc.	California, United States	Medicine,Health care,Biopharmaceutical, ...[+2]	news: 3
25	Huadong Medicine Co., Ltd.	Shanghai Shi, China	Emergency medicine,Medicine,Drug, ...[+2]	news: 3
26	Helen of Troy Ltd.	CITY OF HAMILTON, Bermuda	Air purifier,Electronics,Thermometer, ...[+2]	news: 3
27	Google LLC	California, United States	Advertising,Enterprise software,Search engine, ...[+2]	news: 3
28	Happiness & D Co., Ltd.	Tokyo, Japan	Candle,Shopping mall	news: 3
29	CODI-M Co., Ltd.	South Korea	Automation,Manufacturing engineering,Industrial engineering, ...[+2]	news: 3
30	International Olympic Committee	Vaud, Switzerland	Executive board,sports equipment,Conference management, ...[+1]	news: 3
31	Lilly Ventures Management Co. LLC	Indiana, United States	Venture capital,Biology,Impact investing, ...[+2]	news: 3
32	Dura Pharmaceuticals, Inc.	Utah, United States	Inhaler,Health care,Core product	news: 3
33	Hatteras Venture Partners	North Carolina, United States	Venture capital,Biopharmaceutical,Health care, ...[+2]	news: 3
34	Howard Hughes Medical Institute	United States	Science education,Medical equipment,Health care, ...[+2]	news: 3
35	Partners Innovation Fund	Massachusetts, United States	Medical equipment,Health care,Gene delivery, ...[+2]	news: 3
36	Roche Ventures	Basel-Stadt, Switzerland	Health care,Venture capital,DNA damage, ...[+2]	news: 3
37	Corporate Communications	New York, United States	Marketing strategy,Web development,Web design, ...[+2]	news: 3
38	STARTUP Asterias Biotherapeutics, Inc.	California, United States	Biology,Medicine,Pharmacy and Therapeutics, ...[+2]	news: 3
39	Valerion Therapeutics LLC	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,Alglucosidase alfa, ...[+2]	news: 3
40	Asterias Ltd.	United Kingdom		news: 3
41	Mumm's Sprouting Seeds Ltd.	Saskatchewan, Canada	Sprouting,Agriculture	news: 3
42	The Royal Manchester Childrens Hospital	United Kingdom	Health care	news: 3
43	FDA Sdn. Bhd.	Malaysia	Real estate development	news: 3
44	GSK Plc	United Kingdom	Health care,Clinical trial,Drug, ...[+2]	news: 2
45	General Motors Co.	Michigan, United States	Sport utility vehicle,Public transport,Enterprise software, ...[+2]	news: 2
46	J Sainsbury Plc	United Kingdom	Digital marketing,Warehouse,Hypermarket, ...[+2]	news: 2
47	Bank of China Ltd.	Beijing Shi, China	Venture capital,Current account,Underwriting, ...[+2]	news: 2
48	Biogen, Inc.	Massachusetts, United States	Neuroscience,Medicine,Health care, ...[+2]	news: 2
49	Novo Nordisk A/S	Hovedstaden, Denmark	Insulin,Health care,Haemophilia, ...[+2]	news: 2
50	Japan Post Holdings Co., Ltd.	Tokyo, Japan	Parcel delivery,Military logistics,Underwriting, ...[+2]	news: 2
51	Bath & Body Works, Inc.	Ohio, United States	Hand sanitizer,E-commerce,Lifestyle business, ...[+2]	news: 2
52	Tachi-S Co., Ltd.	Tokyo, Japan	Head restraint,Car seat,Automotive engineering, ...[+2]	news: 2
53	en Japan, Inc.	Tokyo, Japan	Contingency,Performance improvement,Antibiotics, ...[+2]	news: 2
54	CTI BioPharma Corp.	Washington, United States	Oncology,Medicine,Health care, ...[+2]	news: 2
55	All for One Group SE	Vlaams-Brabant, Belgium	Systems design,Business process,Enterprise resource planning, ...[+1]	news: 2
56	B Communications Ltd.	Tel Aviv, Israel	Telecommunications,Condom,International communication, ...[+2]	news: 2
57	Kintetsu Department Store Co., Ltd.	Osaka, Japan	Food products,Fast-moving consumer goods,Warehouse	news: 2
58	Sangamo Therapeutics, Inc.	California, United States	Cell,Pharmacy and Therapeutics,Genomics, ...[+2]	news: 2
59	GeoJunxion NV	Zuid-Holland, Netherlands	Software,Automotive engineering,Navigation system, ...[+2]	news: 2
60	REGENXBIO, Inc.	United States	Gene delivery,Viral vector,Pharmacy and Therapeutics, ...[+2]	news: 2
61	Avalon Ventures Management LLC	California, United States	Venture capital,Biology,Health care, ...[+2]	news: 2
62	National Car Rental System, Inc.	Texas, United States	Renting,Public transport,Building automation, ...[+2]	news: 2
63	Third Rock Ventures LLC	Massachusetts, United States	Medical equipment,Health care,Oncology drugs, ...[+2]	news: 2
64	MP TotalCare, Inc.	United States	Chronic care,E-commerce,Health care, ...[+2]	news: 2
65	Massachusetts General Hospital	Massachusetts, United States	Substance abuse,Hospitality industry,Health care, ...[+2]	news: 2
66	IBM Research	New York, United States	Industrial engineering,Watson,Scanning tunneling microscope, ...[+2]	news: 2
67	Alopexx Enterprises LLC	Massachusetts, United States	Clinical trial,Health care,Medicine, ...[+2]	news: 2
68	STARTUP Casma Therapeutics, Inc.	Massachusetts, United States	Health care,Pharmacy and Therapeutics,Autophagy, ...[+2]	news: 2
69	STARTUP Perlara PBC	California, United States	Medicine,Health care,Pharmacy and Therapeutics, ...[+2]	news: 2
70	Sigma-Aldrich Co. Ltd.	Dorset, United Kingdom	Bovine serum albumin,Medicine,Polymer science, ...[+2]	news: 2
71	Xconomy, Inc.	Massachusetts, United States	News media,Digital media,Conference management	news: 2
72	Beck et al		Digital transformation,Information technology consulting,Software	news: 2
73	STARTUP Diamond	California, United States	Web application,Optoelectronics,Polarizer, ...[+2]	news: 2
74	Orion Healthcare Equity Partners	Massachusetts, United States	Venture capital,Health care	news: 2
75	Northern Care Alliance NHS Foundation Trust	United Kingdom	Health care,Hospitality industry	news: 2
76	Casma Spa	Italy		news: 2
77	Shire International GmbH	CH	Medical equipment,Drug,Medicine, ...[+2]	news: 2
78	Siemens AG	Bayern, Germany	Power transmission,Electronics,Turbine, ...[+2]	news: 1
79	General Electric Co.	Massachusetts, United States	Energy management,Turbine,Electronics, ...[+2]	news: 1
80	International Business Machines Corp.	New York, United States	Software,Computer hardware,Enterprise software, ...[+2]	news: 1
81	BASF SE	Rheinland-Pfalz, Germany	Agriculture,Petrochemical,Chemical engineering, ...[+2]	news: 1
82	Bayer AG	Nordrhein-Westfalen, Germany	Health care,Biology,Chemical engineering, ...[+2]	news: 1
83	Flex Ltd.	Central Region, Singapore	Product design,Electronics,Semiconductor, ...[+2]	news: 1
84	Novartis AG	Basel-Stadt, Switzerland	Dosage form,Health care,Medicine, ...[+2]	news: 1
85	ING Groep NV	Noord-Holland, Netherlands	Private banking,Asset management,Insurance carriers, ...[+2]	news: 1
86	AT&T, Inc.	Texas, United States	Wireless,Telecommunications,Mobile device, ...[+2]	news: 1
87	Thermo Fisher Scientific, Inc.	Massachusetts, United States	Biology,Medical equipment,Reagent, ...[+2]	news: 1
88	BGC Partners, Inc.	New York, United States	Clearing,Property derivative,Emotional security, ...[+2]	news: 1
89	Constellation Software, Inc.	Ontario, Canada	Software,Enterprise software,Industrial engineering, ...[+2]	news: 1
90	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	news: 1
91	Yamaha Motor Co., Ltd.	Shizuoka, Japan	Robotics,Industrial robot,Automotive engineering, ...[+2]	news: 1
92	Laboratory Corp. of America Holdings	North Carolina, United States	Drug development,Health care,Biotechnology, ...[+2]	news: 1
93	Mallinckrodt Plc	Dublin, Ireland	Clinical trial,Generic drug,Medicine, ...[+2]	news: 1
94	Olympus Corp.	Tokyo, Japan	Microscope,Endoscopy,Software, ...[+2]	news: 1
95	Takeda Pharmaceutical Co., Ltd.	Osaka, Japan	Medicine,Health care,Clinical trial, ...[+2]	news: 1
96	Huntington Bancshares, Inc.	OH, US	Coffee bean,Laundry,Money market account, ...[+2]	news: 1
97	Bio-Rad Laboratories, Inc.	California, United States	Medicine,Proteomics,Genomics, ...[+2]	news: 1
98	Nikon Corp.	Tokyo, Japan	Microscope,Photography,Motion capture, ...[+2]	news: 1
99	Astellas Pharma, Inc.	Tokyo, Japan	Health care,Clinical trial,Diabetic complication, ...[+2]	news: 1
100	Dow, Inc.	Michigan, United States	Coating,Chemical engineering,Synthetic rubber, ...[+2]	news: 1