Top 100 Key Players companies in Lysosome by Most News Heat in the world in 2020 – Discovery

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The Lysosome top 100 is Discovery PatSnap’ annual ranking of the top 100 Most News Heat Lysosome Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2020, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

A lysosome (/ˈlaɪsəˌsoʊm/) is a membrane-bound organelle found in many animal cells. They are spherical vesicles that contain hydrolytic enzymes that can break down many kinds of biomolecules. A lysosome has a specific composition, of both its membrane proteins, and its lumenal proteins. The lumen's pH (~4.5–5.0) is optimal for the enzymes involved in hydrolysis, analogous to the activity of the stomach. Besides degradation of polymers, the lysosome is involved in various cell processes, including secretion, plasma membrane repair, cell signaling, and energy metabolism.

1	Orphazyme A/S	Hovedstaden, Denmark	Lysosomal storage disease,Medicine,Pharmacy and Therapeutics, ...[+2]	news: 43
2	European Medicines Agency	United Kingdom	Safety monitoring,Contract research organization,Laboratory testing, ...[+2]	news: 29
3	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	news: 20
4	ET Systems Ltd.	Eastern Cape, South Africa	Electronic security,Electronics,Repeater, ...[+2]	news: 19
5	Sanofi	Île-de-France, France	Health care,Pharmacy and Therapeutics,Drug, ...[+2]	news: 18
6	CytRx Corp.	California, United States	Clinical trial,Health care,Aldoxorubicin, ...[+2]	news: 17
7	Amicus Therapeutics, Inc.	New Jersey, United States	Pharmacological chaperone,Medicine,Health care, ...[+2]	news: 15
8	Provectus Biopharmaceuticals, Inc.	Tennessee, United States	Medicine,Health care,Liver cancer, ...[+2]	news: 15
9	Provectus LLC	California, United States	Software,Blockchain,Cloud computing, ...[+2]	news: 15
10	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	news: 11
11	Thermo Fisher Scientific, Inc.	Massachusetts, United States	Biology,Medical equipment,Reagent, ...[+2]	news: 11
12	Third Rock Ventures LLC	Massachusetts, United States	Medical equipment,Health care,Oncology drugs, ...[+2]	news: 11
13	STARTUP Casma Therapeutics, Inc.	Massachusetts, United States	Health care,Pharmacy and Therapeutics,Autophagy, ...[+2]	news: 11
14	New York Academy of Sciences	New York, United States	Publishing,Conference management,Scientific organization, ...[+2]	news: 11
15	Gilead Sciences, Inc.	California, United States	Medicine,Health care,Biopharmaceutical, ...[+2]	news: 10
16	Alexion Pharmaceuticals, Inc.	Connecticut, United States	Health care,Biopharmaceutical,Clinical trial, ...[+2]	news: 10
17	Howard Hughes Medical Institute	United States	Science education,Medical equipment,Health care, ...[+2]	news: 10
18	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	news: 9
19	ImmunityBio, Inc.	California, United States	Health care,Pharmacy and Therapeutics,Oncology drugs, ...[+2]	news: 8
20	STARTUP Amicus	Delhi, India	Algorithm,E-commerce,Data integration, ...[+2]	news: 8
21	Novartis AG	Basel-Stadt, Switzerland	Dosage form,Health care,Medicine, ...[+2]	news: 7
22	Genentech, Inc.	California, United States	Biotechnology,Biology,Medicine, ...[+2]	news: 7
23	Eventide Asset Management LLC	Massachusetts, United States	Asset management,Gene delivery,Mutual fund, ...[+2]	news: 7
24	The Column Group LLC	California, United States	Venture capital,Biotechnology,Oncogene, ...[+2]	news: 7
25	GSK Plc	United Kingdom	Health care,Clinical trial,Drug, ...[+2]	news: 6
26	AT&T, Inc.	Texas, United States	Wireless,Telecommunications,Mobile device, ...[+2]	news: 6
27	Eli Lilly & Co.	Indiana, United States	Medicine,Health care,Humalog Mix, ...[+2]	news: 6
28	Roche Holding AG	Basel-Stadt, Switzerland	Drug,Clinical chemistry,Medicine, ...[+2]	news: 6
29	Atlas Ventures Advisors, Inc.	Massachusetts, United States	Venture capital,Health care,Monoclonal antibody, ...[+2]	news: 6
30	Schroder Adveq Management AG	Zürich, Switzerland	Asset management,RNA,Molecular medicine, ...[+2]	news: 6
31	STARTUP Arkuda Therapeutics, Inc.	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,GRN-related frontotemporal dementia, ...[+2]	news: 6
32	STARTUP Lycia Therapeutics, Inc.	California, United States	Biotechnology,Health care,Biology	news: 6
33	STARTUP Calporta Therapeutics, Inc.	California, United States	Medicine,Health care,Pharmacy and Therapeutics, ...[+2]	news: 6
34	Jones Lang LaSalle, Inc.	Illinois, United States	Facility management,Property (philosophy),Property management, ...[+2]	news: 5
35	Takeda Pharmaceutical Co., Ltd.	Osaka, Japan	Medicine,Health care,Clinical trial, ...[+2]	news: 5
36	Biogen, Inc.	Massachusetts, United States	Neuroscience,Medicine,Health care, ...[+2]	news: 5
37	Huadong Medicine Co., Ltd.	Shanghai Shi, China	Emergency medicine,Medicine,Drug, ...[+2]	news: 5
38	C.H. Boehringer Sohn AG & Co. KG	Rheinland-Pfalz, Germany	Medicine,Human immunodeficiency virus (HIV),Human immunodeficiency, ...[+2]	news: 5
39	Avrobio, Inc.	Massachusetts, United States	Gene,Health care,Cell, ...[+2]	news: 5
40	Merck Sharp & Dohme Corp.	New Jersey, United States	Prescription drug,Medicine,Stroke, ...[+2]	news: 5
41	Parkinson Canada, Inc.	Ontario, Canada	Health care,Generosity	news: 5
42	inc design Ltd.	Manchester, United Kingdom	Advertising	news: 5
43	Beck et al		Digital transformation,Information technology consulting,Software	news: 5
44	SALK spol sro	Czechia	Adult diaper,Real estate development	news: 5
45	Casma Spa	Italy		news: 5
46	General Motors Co.	Michigan, United States	Sport utility vehicle,Public transport,Enterprise software, ...[+2]	news: 4
47	AbbVie, Inc.	Illinois, United States	Health care,Medicine,Biopharmaceutical, ...[+2]	news: 4
48	AstraZeneca Plc	Cambridgeshire, United Kingdom	Medicine,Health care,Side effect, ...[+2]	news: 4
49	Nasdaq, Inc.	New York, United States	Information Dissemination,Capital formation,Structured product, ...[+2]	news: 4
50	Forward Air Corp.	Tennessee, United States	Emergency medicine,Logistics center,Triage, ...[+2]	news: 4
51	Google LLC	California, United States	Advertising,Enterprise software,Search engine, ...[+2]	news: 4
52	CNA Financial Corp.	Illinois, United States	Risk management,Property management,Insurance policy, ...[+2]	news: 4
53	Moderna, Inc.	Massachusetts, United States	Health care,Messenger RNA,Coronavirus disease 2019 (COVID-19), ...[+2]	news: 4
54	Celgene Corp.	New Jersey, United States	Health care,Cytogenetic Abnormality,Medicine, ...[+2]	news: 4
55	Vir Biotechnology, Inc.	California, United States	Biotechnology,Health care,Coronavirus disease 2019 (COVID-19), ...[+2]	news: 4
56	Denali Therapeutics, Inc.	California, United States	Biotechnology,Pharmacy and Therapeutics,Biological process, ...[+2]	news: 4
57	Rocket Pharmaceuticals, Inc.	Cayman Islands	Health care,Gene,Medicine, ...[+2]	news: 4
58	REGENXBIO, Inc.	United States	Gene delivery,Viral vector,Pharmacy and Therapeutics, ...[+2]	news: 4
59	Avalon Ventures Management LLC	California, United States	Venture capital,Biology,Health care, ...[+2]	news: 4
60	Eloxx Pharmaceuticals, Inc.	Massachusetts, United States	Medicine,Mucopolysaccharidosis I,Cystinosis, ...[+2]	news: 4
61	Tekla Capital Management LLC	Massachusetts, United States	Health care,Venture capital,Monoclonal antibody, ...[+2]	news: 4
62	Denali Software, Inc.	California, United States	Software,Systems design,DDR SDRAM, ...[+2]	news: 4
63	Dura Pharmaceuticals, Inc.	Utah, United States	Inhaler,Health care,Core product	news: 4
64	IBM Research	New York, United States	Industrial engineering,Watson,Scanning tunneling microscope, ...[+2]	news: 4
65	Guggenheim Securities LLC	New York, United States	Wilms Tumor Protein,Cancer immunotherapy,Immunotherapy, ...[+2]	news: 4
66	Euronext Paris SA	Île-de-France, France	Market data	news: 4
67	Merck Research Laboratories Massachusetts LLC	Massachusetts, United States	Cancer,Clinical trial,Medicine, ...[+1]	news: 4
68	COI Pharmaceuticals, Inc.	California, United States	Medicine	news: 4
69	Fast Track	California, United States	Clinical trial,Health care,Fast track	news: 4
70	Pure Communications LLC	North Carolina, United States		news: 4
71	STARTUP GT Gain Therapeutics SA	United States	Medicine,Pharmacological chaperone,Gene, ...[+2]	news: 4
72	Lysosomal Therapeutics, Inc.	Massachusetts, United States	Health care,Pharmacy and Therapeutics,Neurodegeneration, ...[+2]	news: 4
73	Polaryx Therapeutics, Inc.	New Jersey, United States	Biotechnology,Medicine,Pharmacy, ...[+2]	news: 4
74	HCQ Ticketmaster, Inc.	Illinois, United States	Software development,Software,Software as a service, ...[+1]	news: 4
75	Yervoy		Metastatic melanoma,Health care,Immune system	news: 4
76	Pfizer Ventures LLC	New York, United States	RNA,CRISPR,Genomics, ...[+2]	news: 4
77	International Business Machines Corp.	New York, United States	Software,Computer hardware,Enterprise software, ...[+2]	news: 3
78	Citigroup, Inc.	New York, United States	Fixed income,Private banking,Investment banking, ...[+2]	news: 3
79	PENN Entertainment, Inc.	Pennsylvania, United States	Ridge	news: 3
80	Cowen, Inc.	New York, United States	Investment banking,Alternative investment,Assets under management, ...[+2]	news: 3
81	Huntington Bancshares, Inc.	OH, US	Coffee bean,Laundry,Money market account, ...[+2]	news: 3
82	Bank of China Ltd.	Beijing Shi, China	Venture capital,Current account,Underwriting, ...[+2]	news: 3
83	Amgen, Inc.	California, United States	Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER, ...[+2]	news: 3
84	Investor AB	Sweden	Investment company,Surgical mask,Alginate dressing, ...[+2]	news: 3
85	Wuxi Biologics (Cayman), Inc.	Anhui Sheng, China	Medicine,Health care,Monoclonal antibody, ...[+2]	news: 3
86	Helen of Troy Ltd.	CITY OF HAMILTON, Bermuda	Air purifier,Electronics,Thermometer, ...[+2]	news: 3
87	BioMarin Pharmaceutical, Inc.	California, United States	Software development,Biopharmaceutical,Clinical trial, ...[+2]	news: 3
88	Falck A/S	Hovedstaden, Denmark	Health care,Basic life support,Emergency medicine, ...[+2]	news: 3
89	Genzyme Corp.	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,Multiple sclerosis, ...[+2]	news: 3
90	All for One Group SE	Vlaams-Brabant, Belgium	Systems design,Business process,Enterprise resource planning, ...[+1]	news: 3
91	Sangamo Therapeutics, Inc.	California, United States	Cell,Pharmacy and Therapeutics,Genomics, ...[+2]	news: 3
92	SAN-A CO., LTD.	Okinawa, Japan	Household goods,Electronics,Permanent magnet motor, ...[+2]	news: 3
93	CODI-M Co., Ltd.	South Korea	Automation,Manufacturing engineering,Industrial engineering, ...[+2]	news: 3
94	University Bancorp, Inc.	Michigan, United States	Time deposit,Ultrasonic sensor,Accelerometer, ...[+1]	news: 3
95	House of Jane, Inc.	Arizona, United States	Software,Enterprise software	news: 3
96	NGM Biopharmaceuticals, Inc.	California, United States	Drug discovery,Endocrine system,Health care, ...[+2]	news: 3
97	Choizen Holdings Ltd.	Selangor, Malaysia	Protocol data unit,Systems design,Co-location, ...[+2]	news: 3
98	Massachusetts General Hospital	Massachusetts, United States	Substance abuse,Hospitality industry,Health care, ...[+2]	news: 3
99	Constellation Pharmaceuticals, Inc.	Massachusetts, United States	Epigenetics,Medicine,Health care, ...[+2]	news: 3
100	Argot Partners LLC	New York, United States	Handling crisis,Distress,High-net-worth individual, ...[+2]	news: 3