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Top 100 Key Players companies in Lysosome
by Most News Heat in the United States in 2021

The Lysosome top 100 is Discovery PatSnap’ annual ranking of the top 100 Most News Heat Lysosome Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2021, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
A lysosome (/ˈlaɪsəˌsoʊm/) is a membrane-bound organelle found in many animal cells. They are spherical vesicles that contain hydrolytic enzymes that can break down many kinds of biomolecules. A lysosome has a specific composition, of both its membrane proteins, and its lumenal proteins. The lumen's pH (~4.5–5.0) is optimal for the enzymes involved in hydrolysis, analogous to the activity of the stomach. Besides degradation of polymers, the lysosome is involved in various cell processes, including secretion, plasma membrane repair, cell signaling, and energy metabolism.

Key Players

Fast-growings

Startups & Unicorns

New Entrants

Ranking Year:

2022

2021

2020

2019

2018

Region:

Global

China

Japan

India

United Kingdom

United States

France

Switzerland

Canada

Germany

Sweden

Netherlands

Ranking:

Most Patent Filings

Highest Patent Value

Most Patent Citation

Most Research Publications

Most Literature Citation

Most Market Reports

Most News Heat

#
Company Name
Region
Tech Topics
Total
1
International Business Machines Corp.
New York, United States
Software,Computer hardware,Enterprise software,
...[+2]
news: 29
2
CytRx Corp.
California, United States
Clinical trial,Health care,Aldoxorubicin,
...[+2]
news: 23
3
Merck & Co., Inc.
New Jersey, United States
Health care,Biopharmaceutical,Drug,
...[+2]
news: 22
4
Provectus Biopharmaceuticals, Inc.
Tennessee, United States
Medicine,Health care,Liver cancer,
...[+2]
news: 22
5
Thermo Fisher Scientific, Inc.
Massachusetts, United States
Biology,Medical equipment,Reagent,
...[+2]
news: 20
6
Pfizer Inc.
New York, United States
Health care,Clinical trial,Drug,
...[+2]
news: 19
7
Amicus Therapeutics, Inc.
New Jersey, United States
Pharmacological chaperone,Medicine,Health care,
...[+2]
news: 18
8
GT Gain Therapeutics SA
United States
Medicine,Pharmacological chaperone,Gene,
...[+2]
news: 17
9
Provectus LLC
California, United States
Software,Blockchain,Cloud computing,
...[+2]
news: 16
10
Lycia Therapeutics, Inc.
California, United States
Biotechnology,Health care,Biology
news: 15
11
New York Academy of Sciences
New York, United States
Publishing,Conference management,Scientific organization,
...[+2]
news: 14
12
Bristol Myers Squibb Co.
New York, United States
Medicine,Health care,Oncology drugs,
...[+2]
news: 13
13
Eli Lilly & Co.
Indiana, United States
Medicine,Health care,Humalog Mix,
...[+2]
news: 13
14
Casma Therapeutics, Inc.
Massachusetts, United States
Health care,Pharmacy and Therapeutics,Autophagy,
...[+2]
news: 13
15
Gilead Sciences, Inc.
California, United States
Medicine,Health care,Biopharmaceutical,
...[+2]
news: 11
16
Alexion Pharmaceuticals, Inc.
Connecticut, United States
Health care,Biopharmaceutical,Clinical trial,
...[+2]
news: 11
17
Third Rock Ventures LLC
Massachusetts, United States
Medical equipment,Health care,Oncology drugs,
...[+2]
news: 11
18
Howard Hughes Medical Institute
United States
Science education,Medical equipment,Health care,
...[+2]
news: 11
19
Biogen, Inc.
Massachusetts, United States
Neuroscience,Medicine,Health care,
...[+2]
news: 10
20
Amgen, Inc.
California, United States
Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER,
...[+2]
news: 9
21
Fda Educator
California, United States
news: 9
22
Denali Therapeutics, Inc.
California, United States
Biotechnology,Pharmacy and Therapeutics,Biological process,
...[+2]
news: 8
23
ImmunityBio, Inc.
California, United States
Health care,Pharmacy and Therapeutics,Oncology drugs,
...[+2]
news: 8
24
AT&T, Inc.
Texas, United States
Wireless,Telecommunications,Mobile device,
...[+2]
news: 7
25
AbbVie, Inc.
Illinois, United States
Health care,Medicine,Biopharmaceutical,
...[+2]
news: 7
26
Nasdaq, Inc.
New York, United States
Information Dissemination,Capital formation,Structured product,
...[+2]
news: 7
27
Arvinas, Inc.
Connecticut, United States
Health care,Pharmacy and Therapeutics,Cancer,
...[+2]
news: 7
28
Cyclo Therapeutics, Inc.
United States
Cyclodextrin,Biotechnology,Medicine,
...[+2]
news: 7
29
Genentech, Inc.
California, United States
Biotechnology,Biology,Medicine,
...[+2]
news: 7
30
Eventide Asset Management LLC
Massachusetts, United States
Asset management,Gene delivery,Mutual fund,
...[+2]
news: 7
31
The Column Group LLC
California, United States
Venture capital,Biotechnology,Oncogene,
...[+2]
news: 7
32
GraphPad Software LLC
California, United States
Software,Statistics,Data analysis
news: 7
33
Moderna, Inc.
Massachusetts, United States
Health care,Messenger RNA,Coronavirus disease 2019 (COVID-19),
...[+2]
news: 6
34
Genzyme Corp.
Massachusetts, United States
Medicine,Pharmacy and Therapeutics,Multiple sclerosis,
...[+2]
news: 6
35
Vir Biotechnology, Inc.
California, United States
Biotechnology,Health care,Coronavirus disease 2019 (COVID-19),
...[+2]
news: 6
36
Atlas Ventures Advisors, Inc.
Massachusetts, United States
Venture capital,Health care,Monoclonal antibody,
...[+2]
news: 6
37
Avrobio, Inc.
Massachusetts, United States
Gene,Health care,Cell,
...[+2]
news: 6
38
Arkuda Therapeutics, Inc.
Massachusetts, United States
Medicine,Pharmacy and Therapeutics,GRN-related frontotemporal dementia,
...[+2]
news: 6
39
Gaucher Associates, Inc.
Massachusetts, United States
Human resources
news: 6
40
Calporta Therapeutics, Inc.
California, United States
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
news: 6
41
PENN Entertainment, Inc.
Pennsylvania, United States
Ridge
news: 5
42
Merck Sharp & Dohme Corp.
New Jersey, United States
Prescription drug,Medicine,Stroke,
...[+2]
news: 5
43
IBM Research
New York, United States
Industrial engineering,Watson,Scanning tunneling microscope,
...[+2]
news: 5
44
Caraway Therapeutics, Inc.
Massachusetts, United States
Pharmacy and Therapeutics,Mitophagy,Critical pathways,
...[+2]
news: 5
45
Innosuisse Corp.
Nevada, United States
Computer hardware,Electronics,Guidance system
news: 5
46
Lysosomal Therapeutics, Inc.
Massachusetts, United States
Health care,Pharmacy and Therapeutics,Neurodegeneration,
...[+2]
news: 5
47
Polaryx Therapeutics, Inc.
New Jersey, United States
Biotechnology,Medicine,Pharmacy,
...[+2]
news: 5
48
HCQ Ticketmaster, Inc.
Illinois, United States
Software development,Software,Software as a service,
...[+1]
news: 5
49
UT Southwestern DVA Healthcare LLP
Texas, United States
Dialysis,Library science,Health care,
...[+1]
news: 5
50
Cowen, Inc.
New York, United States
Investment banking,Alternative investment,Assets under management,
...[+2]
news: 4
51
Forward Air Corp.
Tennessee, United States
Emergency medicine,Logistics center,Triage,
...[+2]
news: 4
52
Google LLC
California, United States
Advertising,Enterprise software,Search engine,
...[+2]
news: 4
53
CNA Financial Corp.
Illinois, United States
Risk management,Property management,Insurance policy,
...[+2]
news: 4
54
Celgene Corp.
New Jersey, United States
Health care,Cytogenetic Abnormality,Medicine,
...[+2]
news: 4
55
OrbiMed Advisors LLC
New York, United States
Assets under management,Angel investor,Enzyme,
...[+2]
news: 4
56
Sangamo Therapeutics, Inc.
California, United States
Cell,Pharmacy and Therapeutics,Genomics,
...[+2]
news: 4
57
University Bancorp, Inc.
Michigan, United States
Time deposit,Ultrasonic sensor,Accelerometer,
...[+1]
news: 4
58
REGENXBIO, Inc.
United States
Gene delivery,Viral vector,Pharmacy and Therapeutics,
...[+2]
news: 4
59
Avalon Ventures Management LLC
California, United States
Venture capital,Biology,Health care,
...[+2]
news: 4
60
Kymera Therapeutics, Inc.
Massachusetts, United States
Biotechnology,Health care,Pharmacy and Therapeutics,
...[+2]
news: 4
61
Eloxx Pharmaceuticals, Inc.
Massachusetts, United States
Medicine,Mucopolysaccharidosis I,Cystinosis,
...[+2]
news: 4
62
Tekla Capital Management LLC
Massachusetts, United States
Health care,Venture capital,Monoclonal antibody,
...[+2]
news: 4
63
Xencor, Inc.
California, United States
Monoclonal antibody,Medicine,Health care,
...[+2]
news: 4
64
Spark Therapeutics, Inc.
Pennsylvania, United States
Gene,Medicine,Health care,
...[+2]
news: 4
65
Denali Software, Inc.
California, United States
Software,Systems design,DDR SDRAM,
...[+2]
news: 4
66
UC San Diego Health
California, United States
Health care
news: 4
67
Guggenheim Securities LLC
New York, United States
Wilms Tumor Protein,Cancer immunotherapy,Immunotherapy,
...[+2]
news: 4
68
LifeSci Advisors LLC
New York, United States
Social media
news: 4
69
Safeco Common Stock Trust
United States
Asset management,Impact investing
news: 4
70
Surveyor Capital
Illinois, United States
Surveyor,Market neutral,Gene delivery,
...[+2]
news: 4
71
Interim, Inc.
California, United States
Social support,Affordable housing
news: 4
72
Merck Research Laboratories Massachusetts LLC
Massachusetts, United States
Cancer,Clinical trial,Medicine,
...[+1]
news: 4
73
COI Pharmaceuticals, Inc.
California, United States
Medicine
news: 4
74
Fast Track
California, United States
Clinical trial,Health care,Fast track
news: 4
75
Pure Communications LLC
North Carolina, United States
news: 4
76
General Electric Co.
Massachusetts, United States
Energy management,Turbine,Electronics,
...[+2]
news: 3
77
Citigroup, Inc.
New York, United States
Fixed income,Private banking,Investment banking,
...[+2]
news: 3
78
The Goldman Sachs Group, Inc.
New York, United States
Investment banking,Venture capital,Underwriting,
...[+2]
news: 3
79
General Motors Co.
Michigan, United States
Sport utility vehicle,Public transport,Enterprise software,
...[+2]
news: 3
80
Regeneron Pharmaceuticals, Inc.
New York, United States
Monoclonal antibody,Clinical trial,Cholesterol,
...[+2]
news: 3
81
Nurix Therapeutics, Inc.
California, United States
Small molecule,Biology,Medicine,
...[+2]
news: 3
82
BeyondSpring, Inc.
New York, United States
Medicine,Plinabulin,Nivolumab,
...[+2]
news: 3
83
House of Jane, Inc.
Arizona, United States
Software,Enterprise software
news: 3
84
NGM Biopharmaceuticals, Inc.
California, United States
Drug discovery,Endocrine system,Health care,
...[+2]
news: 3
85
C4 Therapeutics, Inc.
Massachusetts, United States
Health care,Pharmacy and Therapeutics,Protein degradation,
...[+2]
news: 3
86
Hard to Treat Diseases, Inc.
United States
Mainland China,Automation,Manufacturing engineering,
...[+2]
news: 3
87
Albert Einstein Healthcare Network
Pennsylvania, United States
Health care,Medical imaging,Companion diagnostic,
...[+2]
news: 3
88
Cell Signaling Technology, Inc.
Massachusetts, United States
Cell signaling,Medical equipment,Cell,
...[+2]
news: 3
89
Casdin Capital LLC
New York, United States
Biology,Private placement,Healthcare industry,
...[+2]
news: 3
90
Constellation Pharmaceuticals, Inc.
Massachusetts, United States
Epigenetics,Medicine,Health care,
...[+2]
news: 3
91
Trombley Associates
Massachusetts, United States
Asset management
news: 3
92
Therapeutics, Inc.
California, United States
Drug development,Medicine,Health care,
...[+1]
news: 3
93
Sanofi Ventures
Massachusetts, United States
Corporate venture capital,Health care,Secondary progressive multiple sclerosis,
...[+2]
news: 3
94
Vividion Therapeutics, Inc.
California, United States
Health care,Pharmacy and Therapeutics,Chemical biology,
...[+2]
news: 3
95
Corporate Communications
New York, United States
Marketing strategy,Web development,Web design,
...[+2]
news: 3
96
Vanqua Bio
Illinois, United States
Biotechnology
news: 3
97
For Human Use
California, United States
Interaction design,Web design,Mobile device,
...[+2]
news: 3
98
Argot Partners LLC
New York, United States
Handling crisis,Distress,High-net-worth individual,
...[+2]
news: 3
99
National Academy of Medicine
District of Columbia, United States
International community,Health care
news: 3
100
Central Intelligence Agency
District of Columbia, United States
National security,Network security,Data analysis,
...[+2]
news: 3

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