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Top 100 Key Players companies in Microorganism
by Highest Patent Value in the world in 2018

The Microorganism top 100 is Discovery PatSnap’ annual ranking of the top 100 Highest Patent Value Microorganism Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2018, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
A microorganism, or microbe, is a microscopic organism, which may exist in its single-celled form or in a colony of cells. The possible existence of unseen microbial life was suspected from ancient times, such as in Jain scriptures from 6th century BC India and the 1st century BC book On Agriculture by Marcus Terentius Varro. Microbiology, the scientific study of microorganisms, began with their observation under the microscope in the 1670s by Antonie van Leeuwenhoek. In the 1850s, Louis Pasteur found that microorganisms caused food spoilage, debunking the theory of spontaneous generation. In the 1880s, Robert Koch discovered that microorganisms caused the diseases tuberculosis, cholera and anthrax.
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Company Name
Region
Tech Topics
Total
1
Avg patent value: 13.90 M
2
Health care,Medical equipment,Risperidone,
...[+2]
Avg patent value: 11.05 M
3
Avg patent value: 11.00 M
4
Avg patent value: 10.99 M
5
Avg patent value: 10.94 M
6
Avg patent value: 10.53 M
7
Avg patent value: 10.15 M
8
Sterilecare, Inc.
Avg patent value: 10.09 M
9
Avg patent value: 10.09 M
10
Food industry,Health care,Nutrition,
...[+2]
Avg patent value: 9.76 M
11
Medicine,Health care,Boron,
...[+2]
Avg patent value: 9.51 M
12
Antibiotics,Health care,Medicine,
...[+2]
Avg patent value: 9.28 M
13
Avg patent value: 8.98 M
14
C5 Yeast Co. BV
Avg patent value: 8.98 M
15
Clinical trial,Medicine,Over-the-counter,
...[+2]
Avg patent value: 8.97 M
16
Avg patent value: 8.97 M
17
Avg patent value: 8.97 M
18
Recurrent vulvovaginal candidiasis,Drug,Biomedicine,
...[+2]
Avg patent value: 8.54 M
19
Avg patent value: 8.54 M
20
Alglucosidase alfa,Medicine,Enzyme replacement therapy,
...[+2]
Avg patent value: 8.53 M
21
Antibody,Medicine,Health care,
...[+2]
Avg patent value: 8.52 M
22
Avg patent value: 8.06 M
23
Avg patent value: 8.04 M
24
Avg patent value: 7.94 M
25
Avg patent value: 7.89 M
26
Avg patent value: 7.72 M
27
Botulinum toxin,Medicine,Health care,
...[+2]
Avg patent value: 7.64 M
28
Avg patent value: 7.55 M
29
Avg patent value: 7.51 M
30
Avg patent value: 7.51 M
31
Nutraceutical,Health care,Cosmetics,
...[+2]
Avg patent value: 7.42 M
32
Avg patent value: 7.42 M
33
Wien, Austria
Health care,Pleuromutilin,Medicine,
...[+2]
Avg patent value: 7.41 M
34
Avg patent value: 7.34 M
35
Avg patent value: 7.34 M
36
Medicine,Health care,Tedizolid,
...[+2]
Avg patent value: 7.26 M
37
Avg patent value: 7.16 M
38
Avg patent value: 7.10 M
39
Pharmacy and Therapeutics,CTGF,Idiopathic pulmonary fibrosis,
...[+2]
Avg patent value: 7.07 M
40
Avg patent value: 7.06 M
41
Health care,Biopharmaceutical,Drug,
...[+2]
Avg patent value: 6.98 M
42
Avg patent value: 6.98 M
43
Health care,Proprietary drug,Biotechnology,
...[+2]
Avg patent value: 6.93 M
44
Avg patent value: 6.60 M
45
Avg patent value: 6.60 M
46
Avg patent value: 6.53 M
47
Gastroenterology,Viscosupplementation,Infertility,
...[+2]
Avg patent value: 6.49 M
48
Avg patent value: 6.45 M
49
Avg patent value: 6.18 M
50
Avg patent value: 6.13 M
51
Avg patent value: 6.13 M
52
Medicine,Health care,Microbiome,
...[+2]
Avg patent value: 6.04 M
53
Avg patent value: 5.99 M
54
Avg patent value: 5.92 M
55
Avg patent value: 5.87 M
56
Gastrointestinal agent,Plant Immunity,Health care,
...[+2]
Avg patent value: 5.86 M
57
Avg patent value: 5.83 M
58
Avg patent value: 5.83 M
59
Avg patent value: 5.79 M
60
Avg patent value: 5.74 M
61
Avg patent value: 5.72 M
62
Avg patent value: 5.69 M
63
Abu Dhabi, United Arab Emirates
Avg patent value: 5.61 M
64
Avg patent value: 5.60 M
65
Cancer immunotherapy,Health care,Medicine,
...[+2]
Avg patent value: 5.58 M
66
Avg patent value: 5.58 M
67
Wound healing,Health care,Skin tissue,
...[+2]
Avg patent value: 5.56 M
68
Avg patent value: 5.48 M
69
Avg patent value: 5.46 M
70
Avg patent value: 5.46 M
71
Cultivation System,Farming industry,Agriculture
Avg patent value: 5.33 M
72
Biology,Pharmacy and Therapeutics,Dosing Frequency,
...[+2]
Avg patent value: 5.33 M
73
Avg patent value: 5.28 M
74
Personal Care Product,Medicine,Health care,
...[+2]
Avg patent value: 5.28 M
75
Avg patent value: 5.23 M
76
HaMerkaz, Israel
Avg patent value: 5.22 M
77
Avg patent value: 5.20 M
78
Medicine,Health care,Potency,
...[+2]
Avg patent value: 5.19 M
79
Avg patent value: 5.19 M
80
Avg patent value: 5.16 M
81
Medical equipment,Health care,Optometry,
...[+2]
Avg patent value: 5.08 M
82
Avg patent value: 5.05 M
83
Avg patent value: 5.01 M
84
Avg patent value: 4.99 M
85
Avg patent value: 4.99 M
86
Hemodialysis,Medical equipment,Health care,
...[+2]
Avg patent value: 4.97 M
87
Avg patent value: 4.97 M
88
Avg patent value: 4.96 M
89
Avg patent value: 4.96 M
90
Puerto Rico
Avg patent value: 4.94 M
91
Avg patent value: 4.91 M
92
Health care,Probiotic,Medicine,
...[+2]
Avg patent value: 4.83 M
93
New Ventures,Medicine,Health care,
...[+2]
Avg patent value: 4.82 M
94
Avg patent value: 4.77 M
95
Avg patent value: 4.77 M
96
Avg patent value: 4.75 M
97
Medicine,Health care
Avg patent value: 4.71 M
98
Avg patent value: 4.70 M
99
Avg patent value: 4.70 M
100
Medical equipment,Blood culture,Health care,
...[+2]
Avg patent value: 4.69 M
Page generation time: Jul 21 2025