Top 100 Key Players companies in Microorganism by Highest Patent Value in the United States in 2020 – Discovery

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The Microorganism top 100 is Discovery PatSnap’ annual ranking of the top 100 Highest Patent Value Microorganism Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2020, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

A microorganism, or microbe, is a microscopic organism, which may exist in its single-celled form or in a colony of cells. The possible existence of unseen microbial life was suspected from ancient times, such as in Jain scriptures from 6th century BC India and the 1st century BC book On Agriculture by Marcus Terentius Varro. Microbiology, the scientific study of microorganisms, began with their observation under the microscope in the 1670s by Antonie van Leeuwenhoek. In the 1850s, Louis Pasteur found that microorganisms caused food spoilage, debunking the theory of spontaneous generation. In the 1880s, Robert Koch discovered that microorganisms caused the diseases tuberculosis, cholera and anthrax.

1	Apple, Inc.	California, United States	Software,Computer hardware,Peripheral, ...[+2]	Avg patent value: 13.90 M
2	Johnson & Johnson	New Jersey, United States	Health care,Medical equipment,Risperidone, ...[+2]	Avg patent value: 11.05 M
3	Gilead Biologics, Inc.	Delaware, United States	Medicine	Avg patent value: 11.00 M
4	Kirin-Amgen, Inc.	California, United States	Pharmaceutical drug,Medicine	Avg patent value: 10.99 M
5	Brookhaven Science Associates LLC	New York, United States		Avg patent value: 10.94 M
6	Rinat Neuroscience Corp.	California, United States	Neuroscience,Antibody,Medicine, ...[+2]	Avg patent value: 10.53 M
7	Essex Industries, Inc.	Connecticut, United States	Headframe,Eye protection,Fall protection, ...[+2]	Avg patent value: 10.15 M
8	Aseptica, Inc.	Washington, United States		Avg patent value: 10.09 M
9	Anacor Pharmaceuticals, Inc.	California, United States	Medicine,Health care,Boron, ...[+2]	Avg patent value: 9.51 M
10	Achaogen, Inc.	California, United States	Antibiotics,Health care,Medicine, ...[+2]	Avg patent value: 9.28 M
11	STARTUP Mycovia Pharmaceuticals, Inc.	North Carolina, United States	Recurrent vulvovaginal candidiasis,Drug,Biomedicine, ...[+2]	Avg patent value: 8.54 M
12	Viamet Pharmaceuticals, Inc.	North Carolina, United States	Amphotericin B,Medical equipment,Medicine, ...[+2]	Avg patent value: 8.54 M
13	Medivation Prostate Therapeutics LLC	California, United States	Drug,Medicine	Avg patent value: 8.04 M
14	Oro Agri, Inc.	California, United States	Pesticide,Agriculture,Chemical engineering, ...[+2]	Avg patent value: 7.94 M
15	BASF Plant Science LLC	New Jersey, United States	Starch,Fertilizer,Plant science	Avg patent value: 7.89 M
16	TerraVia Holdings, Inc.	California, United States	Biofuel,Chemical engineering,Algae, ...[+2]	Avg patent value: 7.72 M
17	Revance Therapeutics, Inc.	California, United States	Botulinum toxin,Medicine,Health care, ...[+2]	Avg patent value: 7.64 M
18	Abunda Nutrition, Inc.	California, United States	Nutrition	Avg patent value: 7.55 M
19	Baxalta, Inc.	Illinois, United States	Biopharmaceutical,Medicine,Biotechnology, ...[+2]	Avg patent value: 7.34 M
20	Trius Therapeutics, Inc.	Massachusetts, United States	Medicine,Health care,Tedizolid, ...[+2]	Avg patent value: 7.26 M
21	FibroGen, Inc.	California, United States	Pharmacy and Therapeutics,CTGF,Idiopathic pulmonary fibrosis, ...[+2]	Avg patent value: 7.07 M
22	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	Avg patent value: 6.98 M
23	Merck Sharp & Dohme Corp.	New Jersey, United States	Prescription drug,Medicine,Stroke, ...[+2]	Avg patent value: 6.98 M
24	Athenex, Inc.	New York, United States	Health care,Proprietary drug,Biotechnology, ...[+2]	Avg patent value: 6.93 M
25	Gowan Co. LLC	Arizona, United States	Pesticide,Crop,Agriculture, ...[+2]	Avg patent value: 5.99 M
26	Corbion Biotech, Inc.	United States		Avg patent value: 5.87 M
27	LiveLeaf, Inc.	California, United States	Gastrointestinal agent,Plant Immunity,Health care, ...[+2]	Avg patent value: 5.86 M
28	Wyeth LLC	New Jersey, United States		Avg patent value: 5.79 M
29	Wellstat Therapeutics Corp.	United States	Drug discovery,Pharmacy,Drug development, ...[+2]	Avg patent value: 5.74 M
30	Nutrition & Biosciences USA 2 LLC	New York, United States		Avg patent value: 5.72 M
31	Romark LC	United States	Medicine,Medical equipment,Small molecule, ...[+2]	Avg patent value: 5.60 M
32	Bavarian Nordic, Inc.	North Carolina, United States	Drug,Medicine	Avg patent value: 5.58 M
33	Stratatech Corp.	Wisconsin, United States	Wound healing,Health care,Skin tissue, ...[+2]	Avg patent value: 5.56 M
34	H.J. Heinz Company Brands LLC	Illinois, United States	Software as a service,Enterprise software,Software development, ...[+2]	Avg patent value: 5.46 M
35	Ambrx, Inc.	California, United States	Biology,Pharmacy and Therapeutics,Dosing Frequency, ...[+2]	Avg patent value: 5.33 M
36	Constellation Brands, Inc.	New York, United States	Wine,Canopy,Winemaking, ...[+2]	Avg patent value: 5.28 M
37	McNeil-PPC, Inc.	Pennsylvania, United States	Personal Care Product,Medicine,Health care, ...[+2]	Avg patent value: 5.28 M
38	Genentech, Inc.	California, United States	Biotechnology,Biology,Medicine, ...[+2]	Avg patent value: 5.20 M
39	Avent, Inc.	Arizona, United States	Medicine	Avg patent value: 5.16 M
40	Johnson & Johnson Vision Care, Inc.	United States	Medical equipment,Health care,Optometry, ...[+2]	Avg patent value: 5.08 M
41	Progen Pharmaceuticals, Inc.	North Carolina, United States	Medicine	Avg patent value: 4.99 M
42	ExThera Medical Corp.	California, United States	Hemodialysis,Medical equipment,Health care, ...[+2]	Avg patent value: 4.97 M
43	Allied Bioscience, Inc.	Texas, United States	Antimicrobial surface,Mildew,Algae, ...[+2]	Avg patent value: 4.96 M
44	Regeneron Pharmaceuticals, Inc.	New York, United States	Monoclonal antibody,Clinical trial,Cholesterol, ...[+2]	Avg patent value: 4.91 M
45	Avery Dennison Corp.	California, United States	Adhesive,Radio-frequency identification,Synthetic rubber, ...[+2]	Avg patent value: 4.77 M
46	Johnson & Johnson Consumer, Inc.	New Jersey, United States	Skin care,Shower gel,Baby powder, ...[+2]	Avg patent value: 4.70 M
47	Genelux Corp.	California, United States	Drug,Immunotherapy,Biopharmaceutical, ...[+2]	Avg patent value: 4.70 M
48	Magnolia Medical Technologies, Inc.	Washington, United States	Medical equipment,Blood culture,Health care, ...[+2]	Avg patent value: 4.69 M
49	Foresight Biotherapeutics, Inc.	New York, United States	Pharmacy and Therapeutics,Ophthalmology,Drug development, ...[+2]	Avg patent value: 4.31 M
50	Molecular Templates, Inc.	Texas, United States	Health care,Pharmacy and Therapeutics,Biopharmaceutical, ...[+2]	Avg patent value: 4.30 M
51	ImmunityBio, Inc.	California, United States	Health care,Pharmacy and Therapeutics,Oncology drugs, ...[+2]	Avg patent value: 4.28 M
52	Microbion Corp.	United States	Microbial Biofilms,Medicine,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 4.27 M
53	Innovative BioDefense, Inc.	California, United States	Health care,Hand washing,Surgical scrub, ...[+2]	Avg patent value: 4.23 M
54	Rebiotix, Inc.	Minnesota, United States	Microbiome,Medicine,Health care, ...[+2]	Avg patent value: 4.21 M
55	Pfizer Products, Inc.	Connecticut, United States		Avg patent value: 4.20 M
56	Mastertaste, Inc.	New Jersey, United States	Chemical engineering	Avg patent value: 4.08 M
57	South Dakota Board of Regents	South Dakota, United States	Public university,Materials science,Polymer, ...[+2]	Avg patent value: 4.07 M
58	Nutrition & Biosciences USA 4, Inc.	Delaware, United States		Avg patent value: 4.07 M
59	Aveston Grifford Ltd.	United States		Avg patent value: 4.06 M
60	PDS Biotechnology Corp.	New Jersey, United States	Medicine,Health care,Biotechnology, ...[+2]	Avg patent value: 4.04 M
61	Regents of The University of Michigan	Michigan, United States	Cardiovascular agent,Drug marketing,Asset management	Avg patent value: 4.03 M
62	Progenics Pharmaceuticals, Inc.	New York, United States	Medicine,Biopharmaceutical,Methylnaltrexone Bromide, ...[+2]	Avg patent value: 3.99 M
63	Iovance Biotherapeutics, Inc.	New York, United States	Metastatic melanoma,Medicine,Health care, ...[+2]	Avg patent value: 3.97 M
64	Epitopix LLC	Minnesota, United States	Medicine,Pasteurella multocida,Klebsiella pneumoniae, ...[+2]	Avg patent value: 3.95 M
65	Zurex Pharma, Inc.	Wisconsin, United States	Catheter,Medical equipment,Health care, ...[+1]	Avg patent value: 3.92 M
66	Genencor International Indiana, Inc.	Michigan, United States		Avg patent value: 3.91 M
67	Oragenics, Inc.	United States	Antibiotics,Probiotic,Medicine, ...[+2]	Avg patent value: 3.86 M
68	LifeCell Corp.	New Jersey, United States	Hernia repair,Breast reconstruction,Software development, ...[+2]	Avg patent value: 3.74 M
69	Ventana Medical Systems, Inc.	Arizona, United States	Medical equipment,Health care,Digital pathology, ...[+2]	Avg patent value: 3.73 M
70	UNICORN Impossible Foods, Inc.	California, United States	Fish products,Mycoprotein,Nutrition, ...[+2]	Avg patent value: 3.72 M
71	Mannatech, Inc.	Texas, United States	Nutraceutical,Sales management,Medicine, ...[+2]	Avg patent value: 3.71 M
72	International Flavors & Fragrances, Inc.	New York, United States	Preservative,Odor,Food processing, ...[+2]	Avg patent value: 3.70 M
73	Zoetis Services LLC	New Jersey, United States	Drug,Medicine,Vertical farming, ...[+2]	Avg patent value: 3.64 M
74	Quorum Innovations LLC	United States	Probiotic,Microbiome,Medicine, ...[+2]	Avg patent value: 3.64 M
75	Fluoresentric, Inc.	Utah, United States	Molecular diagnostics,Assay,Polymerase chain reaction	Avg patent value: 3.63 M
76	Arch Wood Protection, Inc.	United States	Preservative,Chemical engineering	Avg patent value: 3.57 M
77	Hyprotech, Inc.	Texas, United States	Software,Enterprise software	Avg patent value: 3.56 M
78	TriMed Biotech, Inc.	California, United States	Medical equipment,Medicine,Dental Equipment	Avg patent value: 3.55 M
79	Novozymes North America, Inc.	North Carolina, United States	Feed additive,Chemical engineering	Avg patent value: 3.53 M
80	Therabiome LLC	New Jersey, United States		Avg patent value: 3.51 M
81	DPx Holdings BV	Massachusetts, United States	Health care,Pharmaceutical manufacturing,Manufacturing capability, ...[+2]	Avg patent value: 3.47 M
82	Novozymes Biotech, Inc.	United States		Avg patent value: 3.45 M
83	GeneWEAVE	California, United States	Clinical trial,Antibiotic Stewardship,Drug resistance, ...[+2]	Avg patent value: 3.42 M
84	GeneWeave Biosciences, Inc.	California, United States	In vitro,Health care,Molecular systems, ...[+1]	Avg patent value: 3.42 M
85	Xyleco, Inc.	Massachusetts, United States	Renewable energy,Sugar,Biomass	Avg patent value: 3.37 M
86	Pfenex, Inc.	California, United States	Biosimilar,Medicine,Health care, ...[+2]	Avg patent value: 3.32 M
87	AgroFresh, Inc.	Pennsylvania, United States	Ethylene,Pesticide,Agriculture, ...[+2]	Avg patent value: 3.30 M
88	Novozymes Biologicals, Inc.	Virginia, United States	Toxoid,Biopesticide,Virus, ...[+2]	Avg patent value: 3.27 M
89	Zeus Scientific, Inc.	New Jersey, United States	Enzyme,Immunofluorescence,Clinical chemistry, ...[+2]	Avg patent value: 3.26 M
90	STARTUP AgBiome LLC	North Carolina, United States	Agriculture,Microbiome,Agricultural biotechnology, ...[+2]	Avg patent value: 3.25 M
91	Quest Diagnostics Investments LLC	New Jersey, United States	Medical laboratory,Health care	Avg patent value: 3.25 M
92	Teleflex, Inc.	Pennsylvania, United States	Medical equipment,Therapeutic Procedure,Health care, ...[+2]	Avg patent value: 3.24 M
93	Teleflex Medical, Inc.	North Carolina, United States	Medical equipment,Surgical instrument,Health care, ...[+2]	Avg patent value: 3.24 M
94	Sensient Flavors LLC	Indiana, United States	Drug	Avg patent value: 3.24 M
95	MO Bio Laboratories, Inc.	California, United States	Biology,Sterility,Nucleic acid, ...[+2]	Avg patent value: 3.19 M
96	QIAGEN Sciences LLC	United States	Assay,Medicine,Sample preparation	Avg patent value: 3.19 M
97	Baxter International, Inc.	Illinois, United States	Clinical trial,Drug,Hemodialysis, ...[+2]	Avg patent value: 3.18 M
98	Arkion Life Sciences LLC	Delaware, United States	Biotechnology,Drug,Medicine	Avg patent value: 3.17 M
99	Next Proteins, Inc.	California, United States	Food products,Food industry,Snack foods, ...[+1]	Avg patent value: 3.17 M
100	NatureWorks LLC	Minnesota, United States	Biopolymer,Chemical engineering,Natural resource management, ...[+2]	Avg patent value: 3.16 M