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Top 100 Key Players companies in Missense mutation
by Most News Heat in the United States in 2021

The Missense mutation top 100 is Discovery PatSnap’ annual ranking of the top 100 Most News Heat Missense mutation Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2021, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
In genetics, a missense mutation is a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid. It is a type of nonsynonymous substitution.

Key Players

Fast-growings

Startups & Unicorns

New Entrants

Ranking Year:

2022

2021

2019

2018

Region:

Global

China

Japan

India

United States

United Kingdom

Australia

Switzerland

South Korea

Netherlands

Canada

France

Sweden

Germany

Ranking:

Most Patent Filings

Highest Patent Value

Most Patent Citation

Most Research Publications

Most Literature Citation

Most News Heat

#
Company Name
Region
Tech Topics
Total
1
Thermo Fisher Scientific, Inc.
Massachusetts, United States
Biology,Medical equipment,Reagent,
...[+2]
news: 5
2
The Broad Institute, Inc.
Massachusetts, United States
Clinical trial,Biology,Genomics,
...[+2]
news: 5
3
Merck & Co., Inc.
New Jersey, United States
Health care,Biopharmaceutical,Drug,
...[+2]
news: 4
4
Microsoft Corp.
Washington, United States
Software,Operating system,Cloud computing,
...[+2]
news: 4
5
T-Mobile US, Inc.
California, United States
Telecommunications,Wireless,Service innovation,
...[+2]
news: 4
6
Pfizer Inc.
New York, United States
Health care,Clinical trial,Drug,
...[+2]
news: 3
7
Agilent Technologies, Inc.
California, United States
Genomics,Computer hardware,Semiconductor,
...[+2]
news: 3
8
Invitae Corp.
California, United States
Genetic testing,Health care,Genome,
...[+2]
news: 3
9
Pacific Biosciences of California, Inc.
California, United States
Industrial engineering,Biology,Health care,
...[+2]
news: 3
10
Pacific Biomarkers, Inc.
Washington, United States
Health care,Medicine,Drug,
...[+2]
news: 3
11
AT&T, Inc.
Texas, United States
Wireless,Telecommunications,Mobile device,
...[+2]
news: 2
12
Bristol Myers Squibb Co.
New York, United States
Medicine,Health care,Oncology drugs,
...[+2]
news: 2
13
The New York Times Co.
New York, United States
Publishing,Advertising,News media,
...[+2]
news: 2
14
Icahn Enterprises LP
New York, United States
Automotive engineering,Petroleum,Food packaging,
...[+2]
news: 2
15
Alexion Pharmaceuticals, Inc.
Connecticut, United States
Health care,Biopharmaceutical,Clinical trial,
...[+2]
news: 2
16
Puma Biotechnology, Inc.
California, United States
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
news: 2
17
Kura Oncology, Inc.
California, United States
Medicine,Health care,Precision medicine,
...[+2]
news: 2
18
Ambry Genetics Corp.
California, United States
Health care,Genomics,Genetic testing,
...[+2]
news: 2
19
Howard Hughes Medical Institute
United States
Science education,Medical equipment,Health care,
...[+2]
news: 2
20
GenomeWeb LLC
New York, United States
Publishing,Molecular biology,Broadcasting,
...[+2]
news: 2
21
Preeclampsia Foundation
United States
Preeclampsia,Health care,Association (object-oriented programming),
...[+2]
news: 2
22
Wilcoxon
United States
Mid-Atlantic Region
news: 2
23
HCA Healthcare, Inc.
Tennessee, United States
Health care,Hospitality industry,Psychiatric hospital,
...[+2]
news: 1
24
International Business Machines Corp.
New York, United States
Software,Computer hardware,Enterprise software,
...[+2]
news: 1
25
Citigroup, Inc.
New York, United States
Fixed income,Private banking,Investment banking,
...[+2]
news: 1
26
JPMorgan Chase & Co.
New York, United States
Investment banking,Prime brokerage,Financial institution,
...[+2]
news: 1
27
General Motors Co.
Michigan, United States
Sport utility vehicle,Public transport,Enterprise software,
...[+2]
news: 1
28
American Tower Corp.
Massachusetts, United States
Wireless,Distributed antenna system,Structural analysis,
...[+2]
news: 1
29
Eli Lilly & Co.
Indiana, United States
Medicine,Health care,Humalog Mix,
...[+2]
news: 1
30
PENN Entertainment, Inc.
Pennsylvania, United States
Ridge
news: 1
31
Nasdaq, Inc.
New York, United States
Information Dissemination,Capital formation,Structured product,
...[+2]
news: 1
32
Cowen, Inc.
New York, United States
Investment banking,Alternative investment,Assets under management,
...[+2]
news: 1
33
Quest Diagnostics, Inc.
New Jersey, United States
Diagnostic test,Information technology consulting,Health care,
...[+2]
news: 1
34
Electronic Arts, Inc.
California, United States
Software,Video game development,Web development,
...[+2]
news: 1
35
Bio-Rad Laboratories, Inc.
California, United States
Medicine,Proteomics,Genomics,
...[+2]
news: 1
36
Amgen, Inc.
California, United States
Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER,
...[+2]
news: 1
37
Biogen, Inc.
Massachusetts, United States
Neuroscience,Medicine,Health care,
...[+2]
news: 1
38
Illumina, Inc.
California, United States
Molecular diagnostics,Genetic variation,Health care,
...[+2]
news: 1
39
G-III Apparel Group Ltd.
New York, United States
Basketball,Industry 4.0,Cape,
...[+2]
news: 1
40
PPL Corp.
Pennsylvania, United States
Power transmission,Electric power transmission,Liquefied petroleum gas,
...[+2]
news: 1
41
The Children's Place, Inc.
New Jersey, United States
Sleeve
news: 1
42
Pioneer Natural Resources Co.
Texas, United States
Natural gas,Petroleum industry,Petroleum,
...[+2]
news: 1
43
Incyte Corp.
Delaware, United States
Drug discovery,Medical equipment,Medicine,
...[+2]
news: 1
44
Regeneron Pharmaceuticals, Inc.
New York, United States
Monoclonal antibody,Clinical trial,Cholesterol,
...[+2]
news: 1
45
Seagen Inc.
Washington, United States
Antibody-drug conjugate,Medicine,Health care,
...[+2]
news: 1
46
Legacy LifePoint Health, Inc.
Tennessee, United States
Psychiatric hospital,Health care,Hospitality industry,
...[+2]
news: 1
47
Amicus Therapeutics, Inc.
New Jersey, United States
Pharmacological chaperone,Medicine,Health care,
...[+2]
news: 1
48
National Vision Holdings, Inc.
United States
Eyewear,Military Base,Turnaround time
news: 1
49
Moderna, Inc.
Massachusetts, United States
Health care,Messenger RNA,Coronavirus disease 2019 (COVID-19),
...[+2]
news: 1
50
Celgene Corp.
New Jersey, United States
Health care,Cytogenetic Abnormality,Medicine,
...[+2]
news: 1
51
Veeva Systems, Inc.
California, United States
Software,Customer relationship management,Enterprise software,
...[+2]
news: 1
52
Exelixis, Inc.
California, United States
Oncology drugs,Health care,Drug,
...[+2]
news: 1
53
Spectrum Pharmaceuticals, Inc.
Nevada, United States
Biotechnology,Medicine,Health care,
...[+2]
news: 1
54
Deciphera Pharmaceuticals, Inc.
Massachusetts, United States
Kinase,Health care,Pharmacy and Therapeutics,
...[+2]
news: 1
55
Clovis Oncology, Inc.
Colorado, United States
Medicine,Biopharmaceutical,Oncology,
...[+2]
news: 1
56
Banc of California, Inc.
California, United States
Balance sheet
news: 1
57
Blueprint Medicines Corp.
Massachusetts, United States
Medicine,Health care,Cancer,
...[+2]
news: 1
58
Guitar Center, Inc.
California, United States
Guitar,Music,Amplifier,
...[+2]
news: 1
59
Twist Bioscience Corp.
California, United States
Health care,Chemical engineering,DNA,
...[+2]
news: 1
60
Professional Diversity Network, Inc.
Illinois, United States
Software Design and Development,Social network,Software development,
...[+1]
news: 1
61
Fulgent Genetics, Inc.
California, United States
Health care,Gene probe,Genetic testing,
...[+2]
news: 1
62
Guardant Health, Inc.
California, United States
Oncology,Medicine,Health care,
...[+2]
news: 1
63
Diplomat Pharmacy, Inc.
Michigan, United States
Pharmacy,Drug,Specialty pharmacy,
...[+2]
news: 1
64
Geron Corp.
California, United States
Medicine,Telomerase Inhibitor,Imetelstat,
...[+2]
news: 1
65
OncoCyte Corp.
California, United States
Liquid biopsy,Health care,Hospitality industry,
...[+2]
news: 1
66
Axcella Health, Inc.
Massachusetts, United States
Biology,Pharmacy and Therapeutics,Amino acid,
...[+2]
news: 1
67
University Bancorp, Inc.
Michigan, United States
Time deposit,Ultrasonic sensor,Accelerometer,
...[+1]
news: 1
68
Luminex Corp.
Texas, United States
Digital signal processing,Medical equipment,Microsphere,
...[+2]
news: 1
69
Genentech, Inc.
California, United States
Biotechnology,Biology,Medicine,
...[+2]
news: 1
70
Humanigen, Inc.
California, United States
Medicine,Health care,Clinical trial,
...[+2]
news: 1
71
Mirati Therapeutics, Inc.
California, United States
Oncology,Medicine,Health care,
...[+2]
news: 1
72
Radius Health, Inc.
Massachusetts, United States
Menopause,Health care,Drug,
...[+2]
news: 1
73
Centessa Pharmaceuticals Plc
Massachusetts, United States
Drug development
news: 1
74
SPSS, Inc.
Illinois, United States
Software,Predictive analytics,Data mining
news: 1
75
DF Institute LLC
United States
Professional development,Continue education,Accounting
news: 1
76
National Car Rental System, Inc.
Texas, United States
Renting,Public transport,Building automation,
...[+2]
news: 1
77
Black Diamond Therapeutics, Inc.
Massachusetts, United States
Enterprise mobility management,Small molecule,Biology,
...[+2]
news: 1
78
Zacks Investment Management, Inc.
Illinois, United States
Business entity,Profit sharing,Investment advisor,
...[+2]
news: 1
79
Oncology Pharma, Inc.
California, United States
Oncology,Health care,Pharmacy and Therapeutics
news: 1
80
Foundation Medicine, Inc.
Massachusetts, United States
Cancer therapy,Diagnostic test,Health care,
...[+2]
news: 1
81
Biocept, Inc.
California, United States
Health care,Circulating tumor DNA,Circulating tumor cell,
...[+2]
news: 1
82
Spark Therapeutics, Inc.
Pennsylvania, United States
Gene,Medicine,Health care,
...[+2]
news: 1
83
The Brigham & Women's Hospital, Inc.
Massachusetts, United States
Health care,Mitral valve surgery,Health equity,
...[+2]
news: 1
84
Rain Therapeutics, Inc.
California, United States
Cancer,Health care,Pharmacy and Therapeutics,
...[+2]
news: 1
85
Zacks Investment Research, Inc.
Illinois, United States
Quantitative model,Oscilloscope,Investment style,
...[+2]
news: 1
86
GeneDx, Inc.
United States
Genetic testing,Genomics,Incubator,
...[+2]
news: 1
87
OSI Pharmaceuticals, Inc.
New York, United States
Medicine,Health care,Software development,
...[+2]
news: 1
88
Assembly
New York, United States
Advertising
news: 1
89
Massachusetts General Hospital
Massachusetts, United States
Substance abuse,Hospitality industry,Health care,
...[+2]
news: 1
90
IBM Research
New York, United States
Industrial engineering,Watson,Scanning tunneling microscope,
...[+2]
news: 1
91
Cleveland Clinic
OH, US
Health care,Face transplant,Coronary artery bypass surgery,
...[+2]
news: 1
92
Ohio State University Comprehensive Cancer Center
Ohio, United States
Health care,Cancer,Substance abuse,
...[+2]
news: 1
93
Guggenheim Securities LLC
New York, United States
Wilms Tumor Protein,Cancer immunotherapy,Immunotherapy,
...[+2]
news: 1
94
JAMG LLC
United States
Asset management
news: 1
95
PierianDx, Inc.
Missouri, United States
Genomic sequencing,Software,Health care,
...[+2]
news: 1
96
GSK Equity Investments Ltd
Massachusetts, United States
Corporate venture capital,Health care,Venture capital,
...[+2]
news: 1
97
McLean Hospital, Inc.
Massachusetts, United States
Mental illness,Mental health,Substance abuse,
...[+2]
news: 1
98
Knopp Biosciences LLC
Pennsylvania, United States
Clinical trial,Drug discovery,Health care,
...[+2]
news: 1
99
EMD Serono, Inc.
Massachusetts, United States
Fertility,Medicine,Health care,
...[+2]
news: 1
100
National Academy of Engineering
District of Columbia, United States
Revenue code,Engineering education,Well-being,
...[+2]
news: 1

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