Top 100 Key Players companies in Monoclonal antibody by Highest Patent Value in the world in 2022 – Discovery

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The Monoclonal antibody top 100 is Discovery PatSnap’ annual ranking of the top 100 Highest Patent Value Monoclonal antibody Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2022, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell. Monoclonal antibodies can have monovalent affinity, in that they bind to the same epitope (the part of an antigen that is recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different plasma cell (antibody secreting immune cell) lineages. Bispecific monoclonal antibodies can also be engineered, by increasing the therapeutic targets of one single monoclonal antibody to two epitopes.

1	Gilead Biologics, Inc.	Delaware, United States	Medicine	Avg patent value: 11.64 M
2	ESBATech AG	Zürich, Switzerland	Antibody,Health care,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 11.06 M
3	Merck Sharp & Dohme BV	Noord-Brabant, Netherlands	Drug,Medicine	Avg patent value: 11.05 M
4	Allergan, Inc.	CA, US	Over-the-counter,Dermatology,Botanical drug, ...[+2]	Avg patent value: 11.04 M
5	Omt Spa	Bergamo, Italy	Automation,Manufacturing engineering,Industrial engineering, ...[+2]	Avg patent value: 11.03 M
6	Weiman Products LLC	Illinois, United States	E-commerce,Food industry,Fast-moving consumer goods, ...[+2]	Avg patent value: 10.57 M
7	Bayer Schering Pharma AG	Berlin, Germany	Medicine,Botanical drug,Herb	Avg patent value: 10.25 M
8	Alexion Pharmaceuticals, Inc.	Connecticut, United States	Health care,Biopharmaceutical,Clinical trial, ...[+2]	Avg patent value: 9.85 M
9	Baxter International, Inc.	Illinois, United States	Clinical trial,Drug,Hemodialysis, ...[+2]	Avg patent value: 9.70 M
10	Baxter Healthcare SA	Zürich, Switzerland	Healthcare system,Medicine	Avg patent value: 9.70 M
11	XOMA Technology Ltd.	Bermuda	Medicine	Avg patent value: 9.57 M
12	UCB Pharma SA (Belgium)	BU, BE	Severe disease,Central nervous system,Immune system, ...[+2]	Avg patent value: 9.46 M
13	UCB Celltech	United Kingdom	Medicine	Avg patent value: 9.46 M
14	Kyowa Hakko Kogyo Co., Ltd.	Tokyo, Japan	Fertilizer,Agrochemical,Raw material, ...[+2]	Avg patent value: 9.26 M
15	Baxalta GmbH	Zürich, Switzerland	Drug,Medicine	Avg patent value: 9.21 M
16	Bayer Intellectual Property GmbH	Nordrhein-Westfalen, Germany		Avg patent value: 9.17 M
17	STARTUP Eagle Biologics, Inc.	Massachusetts, United States	Viscosity,Health care,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 9.08 M
18	Baxalta, Inc.	Illinois, United States	Biopharmaceutical,Medicine,Biotechnology, ...[+2]	Avg patent value: 9.07 M
19	Tanox Biosystems, Inc.	Texas, United States	Immune system,Biotechnology,Agriculture, ...[+2]	Avg patent value: 8.99 M
20	La Jolla Institute for Allergy & Immunology	California, United States	Immune system,Health care,Biomedicine, ...[+2]	Avg patent value: 8.96 M
21	Concortis Biosystems Corp.	California, United States	Biotechnology,Biology,Medicine, ...[+2]	Avg patent value: 8.94 M
22	Eisai Co., Ltd.	Tokyo, Japan	Health care,Over-the-counter,Clinical trial, ...[+2]	Avg patent value: 8.80 M
23	Wyeth LLC	New Jersey, United States		Avg patent value: 8.70 M
24	Cormorant Pharmaceuticals AB	Stockholms Lan, Sweden	Monoclonal antibody,Medicine,Cormorant, ...[+2]	Avg patent value: 8.64 M
25	Merck Serono SA	Hessen, Germany	Biology,Health care,Fertility, ...[+2]	Avg patent value: 8.63 M
26	Ganymed Pharmaceuticals AG	Rheinland-Pfalz, Germany	Gynecology,Companion diagnostic,Therapeutic window, ...[+2]	Avg patent value: 8.61 M
27	Roche Glycart AG	Zürich, Switzerland	Antibody,Medicine,Health care, ...[+2]	Avg patent value: 8.60 M
28	Robert Bosch GmbH	Baden-Württemberg, Germany	Automotive engineering,Mechanical engineering,Electronics, ...[+2]	Avg patent value: 8.56 M
29	Robert Bosch Corp.	Michigan, United States	Shopping mall,Truck	Avg patent value: 8.56 M
30	AXON Neuroscience SE	Larnaca, Cyprus	Axon,Customer relationship management,Health care, ...[+2]	Avg patent value: 8.46 M
31	Sanofi-Aventis U.S. LLC	New Jersey, United States	Manufacturing operations,Medicine,Health care, ...[+2]	Avg patent value: 8.45 M
32	Ono Pharmaceutical Co., Ltd.	Osaka, Japan	Diagnostic Reagent,Medicine,Health care, ...[+2]	Avg patent value: 8.45 M
33	Wyeth Holdings LLC	NJ, US	Agriculture,Chemical engineering,Lime, ...[+2]	Avg patent value: 8.44 M
34	UNICORN Intarcia Therapeutics, Inc.	California, United States	Medicine,Medical equipment,Health care, ...[+2]	Avg patent value: 8.43 M
35	Kirin-Amgen, Inc.	California, United States	Pharmaceutical drug,Medicine	Avg patent value: 8.34 M
36	ZymoGenetics, Inc.	Washington, United States	Medicine,Pharmacy and Therapeutics,Protein chemistry, ...[+2]	Avg patent value: 8.22 M
37	Novartis Vaccines & Diagnostics, Inc.	New Jersey, United States	Health care,Medicine	Avg patent value: 8.19 M
38	Dyax Corp.	Massachusetts, United States	Biopharmaceutical,Monoclonal antibody,Medicine, ...[+2]	Avg patent value: 8.04 M
39	STARTUP True North Therapeutics, Inc.	California, United States	Immunotherapy,Health care,Clinical trial, ...[+2]	Avg patent value: 8.02 M
40	Morphotek, Inc.	Pennsylvania, United States	Monoclonal antibody,Antibody,Health care, ...[+2]	Avg patent value: 7.99 M
41	Millennium Pharmaceuticals, Inc.	Massachusetts, United States	Oncology,Health care,Monoclonal antibody, ...[+2]	Avg patent value: 7.93 M
42	Siva SpA	IT	Coating,Chemical engineering	Avg patent value: 7.91 M
43	Biogen, Inc.	Massachusetts, United States	Neuroscience,Medicine,Health care, ...[+2]	Avg patent value: 7.86 M
44	Amgen Fremont, Inc.	California, United States	Monoclonal antibody therapy,Medicine,Monoclonal antibody	Avg patent value: 7.80 M
45	BioRéalités SAS	France	Colorectal cancer,Medicine,Oncology	Avg patent value: 7.72 M
46	Astellas Pharma, Inc.	Tokyo, Japan	Health care,Clinical trial,Diabetic complication, ...[+2]	Avg patent value: 7.63 M
47	Thyssen Krupp Stahl Gmbh	Germany	Carbon,Electronics,Metal, ...[+1]	Avg patent value: 7.56 M
48	Biotie Therapies GmbH	Germany	Biotechnology,Agriculture,Fishery, ...[+2]	Avg patent value: 7.42 M
49	Amgen Research (Munich) GmbH	Hessen, Germany	Metal powder,Metal	Avg patent value: 7.19 M
50	XOMA (US) LLC	California, United States	Medicine	Avg patent value: 7.15 M
51	Les Laboratoires Servier SAS	Île-de-France, France	Heart failure,Medicine,Clinical trial, ...[+2]	Avg patent value: 7.13 M
52	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	Avg patent value: 7.08 M
53	FibroGen, Inc.	California, United States	Pharmacy and Therapeutics,CTGF,Idiopathic pulmonary fibrosis, ...[+2]	Avg patent value: 7.07 M
54	Teijin Pharma Ltd.	Tokyo, Japan	Medical equipment,Respiratory disease,Oxygen concentrator, ...[+2]	Avg patent value: 7.05 M
55	Gilead Sciences, Inc.	California, United States	Medicine,Health care,Biopharmaceutical, ...[+2]	Avg patent value: 7.04 M
56	Oxurion NV	Vlaams-Brabant, Belgium	Blindness,Biology,Medicine, ...[+2]	Avg patent value: 7.04 M
57	Thrombogenics, Inc.	New York, United States	Biotechnology,Diabetic Eye Disease,Biopharmaceutical, ...[+2]	Avg patent value: 7.04 M
58	Hanmi Science Co., Ltd.	South Korea	Clinical trial,Medicine,Drug repositioning, ...[+2]	Avg patent value: 7.02 M
59	Chiron Corp.	California, United States	Blood testing,Biology,Drug discovery, ...[+2]	Avg patent value: 6.95 M
60	AbbVie Bahamas Ltd.	The Bahamas		Avg patent value: 6.88 M
61	Gilead Calistoga LLC	California, United States	Clinical research	Avg patent value: 6.86 M
62	Zoetis Services LLC	New Jersey, United States	Drug,Medicine,Vertical farming, ...[+2]	Avg patent value: 6.74 M
63	Soligenix, Inc.	New Jersey, United States	Biodefense,Medicine,Health care, ...[+2]	Avg patent value: 6.62 M
64	Abbott GmbH (Germany)	Hessen, Germany	Health care,Medicine	Avg patent value: 6.54 M
65	Elan Pharmaceuticals, LLC	Michigan, United States	Autoimmune disease,Medicine,Enzyme, ...[+2]	Avg patent value: 6.53 M
66	Hexal AG	Bayern, Germany	Biosimilar,Medicine,Health care, ...[+2]	Avg patent value: 6.30 M
67	Biothera, Inc.	Minnesota, United States	Biotechnology,Polysaccharide,Medical equipment, ...[+2]	Avg patent value: 6.29 M
68	AbbVie, Inc.	Illinois, United States	Health care,Medicine,Biopharmaceutical, ...[+2]	Avg patent value: 6.27 M
69	STARTUP Boston Pharmaceuticals, Inc.	Massachusetts, United States	Biotechnology,Drug development,Biopharmaceutical, ...[+2]	Avg patent value: 6.24 M
70	Cambridge Enterprise Ltd.	EA, GB	Asset management,Alternative investment,Gene delivery, ...[+2]	Avg patent value: 6.06 M
71	Regents of the University of California	California, United States	Working capital,Pathology,Companion diagnostic, ...[+2]	Avg patent value: 6.04 M
72	Pfizer Products, Inc.	Connecticut, United States		Avg patent value: 6.00 M
73	AC Immune SA	Vaud, Switzerland	Pharmacy and Therapeutics,Medicine,Biomedicine, ...[+2]	Avg patent value: 5.99 M
74	Aerpio Pharmaceuticals, Inc.	Ohio, United States	Clinical trial,Medicine,Health care, ...[+2]	Avg patent value: 5.99 M
75	Theraclone Sciences, Inc.	Washington, United States	Monoclonal antibody,Health care,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 5.88 M
76	UCB Pharma SA	Cataluña, Spain	Medicine,Chemical engineering,Epilepsy, ...[+2]	Avg patent value: 5.86 M
77	Cantargia AB	Sweden	Receptor,Medical equipment,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 5.76 M
78	Bayer Pharma AG	Berlin, Germany	Medicine,Nuclear medicine,Andrology, ...[+2]	Avg patent value: 5.76 M
79	MedImmune Ltd.	Cambridgeshire, United Kingdom	Molecular engineering,Medicine	Avg patent value: 5.72 M
80	SBI Biotech Co., Ltd.	Tokyo, Japan	Dendritic cell,Clinical trial,Drug development, ...[+2]	Avg patent value: 5.67 M
81	Octapharma AG	Schwyz, Switzerland	Medicine,Health care,Collective responsibility, ...[+2]	Avg patent value: 5.65 M
82	Crucell NV	Zuid-Holland, Netherlands	Health care,Pharmacy and Therapeutics,Drug, ...[+2]	Avg patent value: 5.63 M
83	Janssen Vaccines & Prevention BV	Zuid-Holland, Netherlands	Type I hypersensitivity,Medicine,Cancer immunotherapy, ...[+1]	Avg patent value: 5.63 M
84	cCAM Biotherapeutics Ltd.	HaZafon, Israel	Medicine,Clinical trial,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 5.61 M
85	Medarex, Inc.	New Jersey, United States	Pharmacy and Therapeutics,Medical equipment,Biopharmaceutical, ...[+2]	Avg patent value: 5.58 M
86	Vaccinex, Inc.	New York, United States	Antibody,Medicine,Health care, ...[+2]	Avg patent value: 5.57 M
87	Eisai, Inc.	New Jersey, United States	Health care,Medicine,Managed care, ...[+2]	Avg patent value: 5.51 M
88	Mereo Biopharma 5, Inc.	United States		Avg patent value: 5.48 M
89	Galaxy Biotech LLC	California, United States	Scientific literature,Biotechnology,Medicine, ...[+2]	Avg patent value: 5.47 M
90	Biogen MA, Inc.	Massachusetts, United States	Medicine,Drug,Developmental biology, ...[+2]	Avg patent value: 5.47 M
91	Inhibrx, Inc.	California, United States	Biotechnology,Protein engineering,Orphan diseases, ...[+2]	Avg patent value: 5.41 M
92	Almirall SA	Cataluña, Spain	Medical equipment,Drug,Dermatology, ...[+2]	Avg patent value: 5.39 M
93	Bayer HealthCare AG	Nordrhein-Westfalen, Germany	Health care,Diabetes Therapy,Immunoprotein, ...[+2]	Avg patent value: 5.33 M
94	Bayer Healthcare LLC	New Jersey, United States	Pharmaceutical medicine,Medicine,Computed tomography, ...[+2]	Avg patent value: 5.33 M
95	Grifols Therapeutics, Inc.	North Carolina, United States	Congenital afibrinogenemia,Medicine,Fibrinogen, ...[+1]	Avg patent value: 5.32 M
96	Genmab A/S	Hovedstaden, Denmark	Health care,Antibody,Biotechnology, ...[+2]	Avg patent value: 5.27 M
97	Genmab BV	Netherlands		Avg patent value: 5.27 M
98	Intrinsic Lifesciences LLC	California, United States	Medicine,Hepcidin,Biology, ...[+2]	Avg patent value: 5.26 M
99	CSL Ltd.	New South Wales, Australia	Health care,Clinical trial,Influenza vaccine, ...[+2]	Avg patent value: 5.25 M
100	Astellas Institute for Regenerative Medicine	Massachusetts, United States	Stem cell,Medicine,Health care, ...[+2]	Avg patent value: 5.25 M