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Top 100 Key Players companies in Monoclonal antibody
by Most Patent Citation in the world in 2018

The Monoclonal antibody top 100 is Discovery PatSnap’ annual ranking of the top 100 Most Patent Citation Monoclonal antibody Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2018, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell. Monoclonal antibodies can have monovalent affinity, in that they bind to the same epitope (the part of an antigen that is recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different plasma cell (antibody secreting immune cell) lineages. Bispecific monoclonal antibodies can also be engineered, by increasing the therapeutic targets of one single monoclonal antibody to two epitopes.

Key Players

Fast-growings

Startups & Unicorns

New Entrants

Ranking Year:

2022

2021

2020

2019

2018

Region:

Global

China

Japan

India

United States

Switzerland

United Kingdom

South Korea

Germany

Denmark

Netherlands

Israel

France

Canada

Ranking:

Most Patent Filings

Highest Patent Value

Most Sep Patents

Most Patent Citation

Most Research Publications

Most Literature Citation

Most Market Reports

Most News Heat

#
Company Name
Region
Tech Topics
Total
1
Genentech, Inc.
California, United States
Biotechnology,Biology,Medicine,
...[+2]
patent citation: 13,602
2
Hybritech, Inc.
California, United States
Monoclonal antibody,Health care,Prostate cancer,
...[+2]
patent citation: 7,173
3
Bristol Myers Squibb Co.
New York, United States
Medicine,Health care,Oncology drugs,
...[+2]
patent citation: 6,770
4
Bristol Myers Co.
New York, United States
Botanical drug,Herb
patent citation: 6,770
5
Medarex, Inc.
New Jersey, United States
Pharmacy and Therapeutics,Medical equipment,Biopharmaceutical,
...[+2]
patent citation: 4,780
6
Chugai Pharmaceutical Co., Ltd.
Tokyo, Japan
Drug,Clinical trial,Health care,
...[+2]
patent citation: 4,689
7
Amgen Fremont, Inc.
California, United States
Monoclonal antibody therapy,Medicine,Monoclonal antibody
patent citation: 4,519
8
Biogen, Inc.
Massachusetts, United States
Neuroscience,Medicine,Health care,
...[+2]
patent citation: 4,388
9
Ciba-Geigy AG
Switzerland
Botanical drug,Herb
patent citation: 3,988
10
Aronex Pharmaceuticals, Inc.
Gujarat, India
Health care,Antibiotics,Medical product,
...[+2]
patent citation: 3,830
11
Immunomedics, Inc.
New Jersey, United States
Biopharmaceutical,Medicine,Health care,
...[+2]
patent citation: 3,656
12
Abgenix, Inc.
California, United States
Antibody,Pharmacy and Therapeutics,Lead compound,
...[+2]
patent citation: 3,492
13
Mesoblast International SARL
Switzerland
patent citation: 3,469
14
Massachusetts General Hospital
Massachusetts, United States
Substance abuse,Hospitality industry,Health care,
...[+2]
patent citation: 3,117
15
The General Hospital Corp.
Massachusetts, United States
Health care,Hospitality industry,Vascular Medicine,
...[+2]
patent citation: 3,117
16
Kyowa Kirin Co., Ltd.
Tokyo, Japan
Health care,Drug,Medicine,
...[+2]
patent citation: 2,758
17
Immunex Corp.
Washington, United States
Medicine,Health care,Leukemia,
...[+2]
patent citation: 2,369
18
Ono Pharmaceutical Co., Ltd.
Osaka, Japan
Diagnostic Reagent,Medicine,Health care,
...[+2]
patent citation: 2,297
19
BioInvent International AB
Sweden
Antibody,Medicine,Biotechnology,
...[+2]
patent citation: 2,294
20
MedImmune Ltd.
Cambridgeshire, United Kingdom
Molecular engineering,Medicine
patent citation: 2,193
21
Celltech Co., Ltd.
South Korea
Good manufacturing practice,Cell therapy,Drug,
...[+2]
patent citation: 2,186
22
LFB USA, Inc.
Massachusetts, United States
Biotechnology,Drug,Medicine
patent citation: 2,154
23
Pfizer Inc.
New York, United States
Health care,Clinical trial,Drug,
...[+2]
patent citation: 2,122
24
Merck Patent GmbH
Hessen, Germany
patent citation: 2,094
25
Center For Molecular Immunology
Ciudad de la Habana, Cuba
Association (object-oriented programming),Monoclonal antibody,Basic research,
...[+2]
patent citation: 2,023
26
Tanox Biosystems, Inc.
Texas, United States
Immune system,Biotechnology,Agriculture,
...[+2]
patent citation: 1,942
27
Genmab A/S
Hovedstaden, Denmark
Health care,Antibody,Biotechnology,
...[+2]
patent citation: 1,795
28
Genmab BV
Netherlands
patent citation: 1,795
29
Novartis AG
Basel-Stadt, Switzerland
Dosage form,Health care,Medicine,
...[+2]
patent citation: 1,770
30
MacroGenics, Inc.
United States
Monoclonal antibody,Medicine,Health care,
...[+2]
patent citation: 1,760
31
Alexion Pharmaceuticals, Inc.
Connecticut, United States
Health care,Biopharmaceutical,Clinical trial,
...[+2]
patent citation: 1,695
32
CureTech Ltd.
HaMerkaz, Israel
Biotechnology,Health care,Cancer,
...[+2]
patent citation: 1,686
33
Merck & Co., Inc.
New Jersey, United States
Health care,Biopharmaceutical,Drug,
...[+2]
patent citation: 1,665
34
Chiron Corp.
California, United States
Blood testing,Biology,Drug discovery,
...[+2]
patent citation: 1,646
35
Becton, Dickinson & Co.
Haryana, India
Medical equipment,Health care,Surgical Specialty,
...[+2]
patent citation: 1,637
36
Becton, Dickinson & Co. Ltd.
Dublin, Ireland
Medical equipment,Medicine
patent citation: 1,637
37
Smithkline Beckman Corp
Pennsylvania, United States
Biotechnology,Medicine
patent citation: 1,537
38
Biovation Ltd.
Aberdeen City, United Kingdom
Cuff,Diagnostic agent,Protein engineering,
...[+1]
patent citation: 1,517
39
Amgen, Inc.
California, United States
Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER,
...[+2]
patent citation: 1,408
40
Yeda Research & Development Co. Ltd.
HaMerkaz, Israel
Association (object-oriented programming),Intellectual property,Biotechnology,
...[+2]
patent citation: 1,382
41
Merck Sharp & Dohme Corp.
New Jersey, United States
Prescription drug,Medicine,Stroke,
...[+2]
patent citation: 1,293
42
Abbott Laboratories Ltd.
United Kingdom
Medicine,Photomedicine,Drug carrier,
...[+2]
patent citation: 1,279
43
Oncogen Corp.
WA, US
patent citation: 1,278
44
Institut National de la Santé et de la Recherche Médicale
Île-de-France, France
Public health,Genomics,Antisense therapy,
...[+2]
patent citation: 1,249
45
INSERM Limoges
E-commerce
patent citation: 1,249
46
Teijin Ltd.
Tokyo, Japan
Synthetic rubber,Chemical engineering,Polycarbonate,
...[+2]
patent citation: 1,223
47
Eli Lilly & Co.
Indiana, United States
Medicine,Health care,Humalog Mix,
...[+2]
patent citation: 1,181
48
Kyowa Hakko Kogyo Co., Ltd.
Tokyo, Japan
Fertilizer,Agrochemical,Raw material,
...[+2]
patent citation: 1,175
49
Novartis Vaccines & Diagnostics, Inc.
New Jersey, United States
Health care,Medicine
patent citation: 1,164
50
Seagen Inc.
Washington, United States
Antibody-drug conjugate,Medicine,Health care,
...[+2]
patent citation: 1,161
51
Chimerix, Inc.
North Carolina, United States
Medicine,Health care,Virus,
...[+2]
patent citation: 1,158
52
BASF SE
Rheinland-Pfalz, Germany
Agriculture,Petrochemical,Chemical engineering,
...[+2]
patent citation: 1,153
53
ImClone LLC
New Jersey, United States
Bevacizumab,Medicine,Blood cell,
...[+2]
patent citation: 1,130
54
Cetus Corp.
California, United States
Botanical drug,Herb
patent citation: 1,118
55
Sigma-Aldrich, Inc.
Missouri, United States
Biotechnology,Biology,Chemical engineering,
...[+2]
patent citation: 1,092
56
Sigma-Aldrich Co. Ltd.
Dorset, United Kingdom
Bovine serum albumin,Medicine,Polymer science,
...[+2]
patent citation: 1,092
57
Takeda Pharmaceutical Co., Ltd.
Osaka, Japan
Medicine,Health care,Clinical trial,
...[+2]
patent citation: 1,067
58
Takeda Chemical Industries Ltd.
Japan
Pharmaceutical drug,Botanical drug,Herb
patent citation: 1,067
59
F. Hoffmann-La Roche Ltd.
Switzerland
Medicine,Health care,Drug,
...[+2]
patent citation: 1,063
60
Labsystems Oy
Finland
Graphics processing unit,Information technology management,Doppler ultrasound,
...[+2]
patent citation: 1,009
61
Biogen MA, Inc.
Massachusetts, United States
Medicine,Drug,Developmental biology,
...[+2]
patent citation: 988
62
Boston Scientific Scimed, Inc.
Minnesota, United States
Medical equipment,Health care,Cloud computing,
...[+2]
patent citation: 977
63
Cell Analysis Systems, Inc.
NC, US
Medicine,Cell
patent citation: 951
64
Japan Tobacco, Inc.
Tokyo, Japan
Nicotiana tabacum,Cigarillo,Food sector,
...[+2]
patent citation: 925
65
Siemens Healthcare Diagnostics, Inc.
New York, United States
Vitro diagnostics,Health care,Picture archiving and communication system,
...[+2]
patent citation: 894
66
Epitomics, Inc.
California, United States
Monoclonal antibody,Medicine,Health care,
...[+2]
patent citation: 851
67
Schering Corp.
New Jersey, United States
Hepatitis,Medicine,Allergy
patent citation: 850
68
Novo Nordisk A/S
Hovedstaden, Denmark
Insulin,Health care,Haemophilia,
...[+2]
patent citation: 803
69
SEQUUS Pharmaceuticals, Inc.
California, United States
Biopharmaceutical,Oncology drugs,Clinical trial,
...[+1]
patent citation: 791
70
ZymoGenetics, Inc.
Washington, United States
Medicine,Pharmacy and Therapeutics,Protein chemistry,
...[+2]
patent citation: 770
71
Galaxy Biotech LLC
California, United States
Scientific literature,Biotechnology,Medicine,
...[+2]
patent citation: 694
72
Bayer HealthCare AG
Nordrhein-Westfalen, Germany
Health care,Diabetes Therapy,Immunoprotein,
...[+2]
patent citation: 680
73
Bayer HealthCare Pharmaceuticals, Inc.
New Jersey, United States
Medicine,Cardiovascular agent,Clinical trial,
...[+2]
patent citation: 678
74
Bayer Healthcare LLC
New Jersey, United States
Pharmaceutical medicine,Medicine,Computed tomography,
...[+2]
patent citation: 667
75
Novimmune SA
Genève, Switzerland
Monoclonal antibody,Health care,Drug discovery,
...[+2]
patent citation: 663
76
AbbVie Biotherapeutics, Inc.
Illinois, United States
Oncology drugs,Medicine,Oncology,
...[+2]
patent citation: 660
77
Immutep Ltd.
New South Wales, Australia
Clinical trial,Health care,Biopharmaceutical,
...[+2]
patent citation: 649
78
MedImmune LLC
Louisiana, United States
Medicine,Pharmacy and Therapeutics,Autoimmunity,
...[+2]
patent citation: 645
79
Serono Diagnostics, Inc.
Massachusetts, United States
Health care
patent citation: 635
80
Peptor Ltd
Israel
Drug,Health care
patent citation: 633
81
Otsuka Pharmaceutical Co., Ltd.
Tokyo, Japan
Nutraceutical,Health care,Cosmetics,
...[+2]
patent citation: 632
82
Scotgen Ltd.
Staffordshire, United Kingdom
Renewable heat,Waste treatment,Environmental consulting,
...[+1]
patent citation: 620
83
IDEC Pharmaceuticals Corp.
California, United States
Autoimmune disease,Health care,Apomorphine,
...[+2]
patent citation: 619
84
Kirin Brewery Co., Ltd.
Tokyo, Japan
Epoetin alfa,Food industry,Aloe vera,
...[+2]
patent citation: 601
85
Mor Research Applications Ltd.
Tel Aviv, Israel
Gastrointestinal agent,Immunotherapy,Clinical trial,
...[+2]
patent citation: 591
86
Regeneron Pharmaceuticals, Inc.
New York, United States
Monoclonal antibody,Clinical trial,Cholesterol,
...[+2]
patent citation: 574
87
Akzo Nobel NV
Noord-Holland, Netherlands
Coating,Powder coating,Chemical engineering,
...[+2]
patent citation: 566
88
Boehringer Mannheim GmbH
Germany
patent citation: 533
89
Miles, Inc.
Kansas, United States
Mobile app,Chemical engineering
patent citation: 527
90
Celldex Therapeutics, Inc.
New Jersey, United States
Medicine,Health care,Immune system,
...[+2]
patent citation: 525
91
Crucell NV
Zuid-Holland, Netherlands
Health care,Pharmacy and Therapeutics,Drug,
...[+2]
patent citation: 520
92
CytoGen, Inc.
South Korea
Monoclonal antibody,Health care,Liquid biopsy,
...[+2]
patent citation: 520
93
Janssen Vaccines & Prevention BV
Zuid-Holland, Netherlands
Type I hypersensitivity,Medicine,Cancer immunotherapy,
...[+1]
patent citation: 520
94
Cellectis SA
Île-de-France, France
Health care,Genome engineering,Cell therapy,
...[+2]
patent citation: 519
95
Vical, Inc.
California, United States
DNA,Biopharmaceutical,Gene delivery,
...[+2]
patent citation: 507
96
AstraZeneca Plc
Cambridgeshire, United Kingdom
Medicine,Health care,Side effect,
...[+2]
patent citation: 501
97
AstraZeneca UK Ltd.
Cambridgeshire, United Kingdom
Gastrointestinal infections,Medicine,Simvastatin,
...[+2]
patent citation: 501
98
Pierre Fabre Médicament SAS
Île-de-France, France
Oncology,Cosmetics,Pharmacy,
...[+1]
patent citation: 500
99
Genetic Systems Corp.
Washington, United States
patent citation: 495
100
Aventis Holdings, Inc.
Delaware, United States
patent citation: 492

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