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Top 100 Key Players companies in Monoclonal antibody
by Most Patent Citation in the United States in 2019

The Monoclonal antibody top 100 is Discovery PatSnap’ annual ranking of the top 100 Most Patent Citation Monoclonal antibody Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2019, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell. Monoclonal antibodies can have monovalent affinity, in that they bind to the same epitope (the part of an antigen that is recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different plasma cell (antibody secreting immune cell) lineages. Bispecific monoclonal antibodies can also be engineered, by increasing the therapeutic targets of one single monoclonal antibody to two epitopes.

Key Players

Fast-growings

Startups & Unicorns

New Entrants

Ranking Year:

2022

2021

2020

2019

2018

Region:

Global

China

Japan

India

United States

Switzerland

United Kingdom

South Korea

Germany

Denmark

Netherlands

Israel

France

Canada

Ranking:

Most Patent Filings

Highest Patent Value

Most Sep Patents

Most Patent Citation

Most Research Publications

Most Literature Citation

Most Market Reports

Most News Heat

#
Company Name
Region
Tech Topics
Total
1
Genentech, Inc.
California, United States
Biotechnology,Biology,Medicine,
...[+2]
patent citation: 13,602
2
Bristol Myers Squibb Co.
New York, United States
Medicine,Health care,Oncology drugs,
...[+2]
patent citation: 6,770
3
Bristol Myers Co.
New York, United States
Botanical drug,Herb
patent citation: 6,770
4
Medarex, Inc.
New Jersey, United States
Pharmacy and Therapeutics,Medical equipment,Biopharmaceutical,
...[+2]
patent citation: 4,780
5
Amgen Fremont, Inc.
California, United States
Monoclonal antibody therapy,Medicine,Monoclonal antibody
patent citation: 4,519
6
Biogen, Inc.
Massachusetts, United States
Neuroscience,Medicine,Health care,
...[+2]
patent citation: 4,388
7
Immunomedics, Inc.
New Jersey, United States
Biopharmaceutical,Medicine,Health care,
...[+2]
patent citation: 3,656
8
Abgenix, Inc.
California, United States
Antibody,Pharmacy and Therapeutics,Lead compound,
...[+2]
patent citation: 3,492
9
Massachusetts General Hospital
Massachusetts, United States
Substance abuse,Hospitality industry,Health care,
...[+2]
patent citation: 3,117
10
The General Hospital Corp.
Massachusetts, United States
Health care,Hospitality industry,Vascular Medicine,
...[+2]
patent citation: 3,117
11
Immunex Corp.
Washington, United States
Medicine,Health care,Leukemia,
...[+2]
patent citation: 2,369
12
LFB USA, Inc.
Massachusetts, United States
Biotechnology,Drug,Medicine
patent citation: 2,154
13
Pfizer Inc.
New York, United States
Health care,Clinical trial,Drug,
...[+2]
patent citation: 2,122
14
Tanox Biosystems, Inc.
Texas, United States
Immune system,Biotechnology,Agriculture,
...[+2]
patent citation: 1,942
15
MacroGenics, Inc.
United States
Monoclonal antibody,Medicine,Health care,
...[+2]
patent citation: 1,760
16
Alexion Pharmaceuticals, Inc.
Connecticut, United States
Health care,Biopharmaceutical,Clinical trial,
...[+2]
patent citation: 1,695
17
Merck & Co., Inc.
New Jersey, United States
Health care,Biopharmaceutical,Drug,
...[+2]
patent citation: 1,665
18
Chiron Corp.
California, United States
Blood testing,Biology,Drug discovery,
...[+2]
patent citation: 1,646
19
Smithkline Beckman Corp
Pennsylvania, United States
Biotechnology,Medicine
patent citation: 1,537
20
Amgen, Inc.
California, United States
Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER,
...[+2]
patent citation: 1,408
21
Merck Sharp & Dohme Corp.
New Jersey, United States
Prescription drug,Medicine,Stroke,
...[+2]
patent citation: 1,293
22
Eli Lilly & Co.
Indiana, United States
Medicine,Health care,Humalog Mix,
...[+2]
patent citation: 1,181
23
Novartis Vaccines & Diagnostics, Inc.
New Jersey, United States
Health care,Medicine
patent citation: 1,164
24
Seagen Inc.
Washington, United States
Antibody-drug conjugate,Medicine,Health care,
...[+2]
patent citation: 1,161
25
Chimerix, Inc.
North Carolina, United States
Medicine,Health care,Virus,
...[+2]
patent citation: 1,158
26
ImClone LLC
New Jersey, United States
Bevacizumab,Medicine,Blood cell,
...[+2]
patent citation: 1,130
27
Cetus Corp.
California, United States
Botanical drug,Herb
patent citation: 1,118
28
Sigma-Aldrich, Inc.
Missouri, United States
Biotechnology,Biology,Chemical engineering,
...[+2]
patent citation: 1,092
29
Biogen MA, Inc.
Massachusetts, United States
Medicine,Drug,Developmental biology,
...[+2]
patent citation: 988
30
Boston Scientific Scimed, Inc.
Minnesota, United States
Medical equipment,Health care,Cloud computing,
...[+2]
patent citation: 977
31
Siemens Healthcare Diagnostics, Inc.
New York, United States
Vitro diagnostics,Health care,Picture archiving and communication system,
...[+2]
patent citation: 894
32
Epitomics, Inc.
California, United States
Monoclonal antibody,Medicine,Health care,
...[+2]
patent citation: 851
33
Schering Corp.
New Jersey, United States
Hepatitis,Medicine,Allergy
patent citation: 850
34
SEQUUS Pharmaceuticals, Inc.
California, United States
Biopharmaceutical,Oncology drugs,Clinical trial,
...[+1]
patent citation: 791
35
ZymoGenetics, Inc.
Washington, United States
Medicine,Pharmacy and Therapeutics,Protein chemistry,
...[+2]
patent citation: 770
36
Galaxy Biotech LLC
California, United States
Scientific literature,Biotechnology,Medicine,
...[+2]
patent citation: 694
37
Bayer HealthCare Pharmaceuticals, Inc.
New Jersey, United States
Medicine,Cardiovascular agent,Clinical trial,
...[+2]
patent citation: 678
38
Bayer Healthcare LLC
New Jersey, United States
Pharmaceutical medicine,Medicine,Computed tomography,
...[+2]
patent citation: 667
39
AbbVie Biotherapeutics, Inc.
Illinois, United States
Oncology drugs,Medicine,Oncology,
...[+2]
patent citation: 660
40
MedImmune LLC
Louisiana, United States
Medicine,Pharmacy and Therapeutics,Autoimmunity,
...[+2]
patent citation: 645
41
IDEC Pharmaceuticals Corp.
California, United States
Autoimmune disease,Health care,Apomorphine,
...[+2]
patent citation: 619
42
Regeneron Pharmaceuticals, Inc.
New York, United States
Monoclonal antibody,Clinical trial,Cholesterol,
...[+2]
patent citation: 574
43
Miles, Inc.
Kansas, United States
Mobile app,Chemical engineering
patent citation: 527
44
Celldex Therapeutics, Inc.
New Jersey, United States
Medicine,Health care,Immune system,
...[+2]
patent citation: 525
45
Vical, Inc.
California, United States
DNA,Biopharmaceutical,Gene delivery,
...[+2]
patent citation: 507
46
Genetic Systems Corp.
Washington, United States
patent citation: 495
47
Aventis Holdings, Inc.
Delaware, United States
patent citation: 492
48
Raven Biotechnologies, Inc.
California, United States
Health care,Pharmacy and Therapeutics,Biotechnology,
...[+2]
patent citation: 469
49
Morphotek, Inc.
Pennsylvania, United States
Monoclonal antibody,Antibody,Health care,
...[+2]
patent citation: 434
50
ARCH Development Corp.
District of Columbia, United States
Arch
patent citation: 426
51
Open Monoclonal Technology, Inc.
California, United States
Medicine,Genetic engineering,Antibody,
...[+2]
patent citation: 424
52
Washington Research Foundation
Washington, United States
Physical science,Mobile device,Gene delivery,
...[+2]
patent citation: 416
53
The Dow Chemical Co.
Michigan, United States
Coating,Agriculture,Chemical engineering,
...[+2]
patent citation: 414
54
XOMA Corp.
California, United States
Antibody,Software development,Medicine,
...[+2]
patent citation: 406
55
Celtrix Pharmaceuticals, Inc.
California, United States
Generic prescription drug,Medicine,Prescription drug,
...[+1]
patent citation: 406
56
Streck Laboratories International, Inc.
Nebraska, United States
patent citation: 406
57
Rise Technology, Inc.
Massachusetts, United States
Electronic component,Computer hardware,Electronics,
...[+1]
patent citation: 402
58
Roche Diagnostics Corp.
Indiana, United States
Medicine,Urinalysis,Immunoassay,
...[+2]
patent citation: 399
59
Eisai, Inc.
New Jersey, United States
Health care,Medicine,Managed care,
...[+2]
patent citation: 391
60
UAB Research Foundation
Alabama, United States
Biotechnology,Agriculture,Fishery,
...[+2]
patent citation: 383
61
Xenerex Biosciences
California, United States
Antigen,Antibody
patent citation: 377
62
Boehringer Ingelheim Pharmaceuticals, Inc.
Connecticut, United States
Central nervous system,Medicine,Drug,
...[+2]
patent citation: 372
63
Protein Design Labs, Inc.
California, United States
E-commerce,Supply chain management,Turnkey
patent citation: 361
64
Rinat Neuroscience Corp.
California, United States
Neuroscience,Antibody,Medicine,
...[+2]
patent citation: 353
65
Vaccinex, Inc.
New York, United States
Antibody,Medicine,Health care,
...[+2]
patent citation: 330
66
Genzyme Corp.
Massachusetts, United States
Medicine,Pharmacy and Therapeutics,Multiple sclerosis,
...[+2]
patent citation: 322
67
Regents of the University of California
California, United States
Working capital,Pathology,Companion diagnostic,
...[+2]
patent citation: 310
68
Scripps Clinic & Research Foundation
California, United States
patent citation: 303
69
AbbVie, Inc.
Illinois, United States
Health care,Medicine,Biopharmaceutical,
...[+2]
patent citation: 287
70
AVEO Pharmaceuticals, Inc.
Massachusetts, United States
Biopharmaceutical,Medicine,Health care,
...[+2]
patent citation: 283
71
Elan Pharmaceuticals, LLC
Michigan, United States
Autoimmune disease,Medicine,Enzyme,
...[+2]
patent citation: 277
72
CytImmune Sciences, Inc.
United States
Pharmaceutical industry,Health care,Nanomedicine,
...[+2]
patent citation: 268
73
G.D. Searle LLC
Illinois, United States
patent citation: 268
74
Morphogenesis, Inc.
United States
Health care,Pharmacy and Therapeutics,Gene,
...[+2]
patent citation: 264
75
Bayer Pharmaceuticals Corp.
Pennsylvania, United States
patent citation: 262
76
Beckman Instruments, Inc.
Indiana, United States
Medicine,Guidance system
patent citation: 248
77
Genetastix Corp.
California, United States
patent citation: 241
78
Precision Biologics, Inc.
Texas, United States
Cancer vaccine,Pharmacy and Therapeutics,Biotechnology,
...[+2]
patent citation: 238
79
QHSLab, Inc.
New York, United States
Health care,Chronic care,Remote patient monitoring,
...[+2]
patent citation: 226
80
Lexicon Pharmaceuticals, Inc.
Texas, United States
Health care,Clinical trial,Medicine,
...[+2]
patent citation: 220
81
Sunol Molecular Corp.
United States
Tissue factor,Medicine
patent citation: 215
82
OSI Pharmaceuticals, Inc.
New York, United States
Medicine,Health care,Software development,
...[+2]
patent citation: 213
83
Repligen Corp.
Massachusetts, United States
Chromatography,Fast-moving consumer goods,Protein A,
...[+2]
patent citation: 207
84
Apexigen America, Inc.
California, United States
Medicine,Health care,Antibody,
...[+2]
patent citation: 204
85
Pharmacia & Upjohn Co. LLC
Michigan, United States
Drug
patent citation: 202
86
Genetics Institute LLC
United States
Medicine,Health care,Biotechnology,
...[+2]
patent citation: 196
87
Provention Bio, Inc.
New Jersey, United States
Medicine,Health care,Biopharmaceutical,
...[+2]
patent citation: 193
88
Baxter International, Inc.
Illinois, United States
Clinical trial,Drug,Hemodialysis,
...[+2]
patent citation: 192
89
Arch Oncology, Inc.
California, United States
Antibody,Cardiovascular agent,Clinical trial,
...[+2]
patent citation: 192
90
SyntheX, Inc.
California, United States
Biology,Medicine,Pharmacy and Therapeutics,
...[+2]
patent citation: 188
91
Research Development Foundation
United States
Plasmid,Molecular medicine,Cardiovascular agent,
...[+2]
patent citation: 187
92
Human Genome Sciences, Inc.
United States
Medicine,Health care,Biopharmaceutical,
...[+2]
patent citation: 186
93
Trustees of Dartmouth College
New Hampshire, United States
Asset management,Impact investing
patent citation: 182
94
Aegis Therapeutics LLC
California, United States
Medicine,Biotechnology,Clobazam,
...[+2]
patent citation: 182
95
Beckman Coulter, Inc.
California, United States
Medical equipment,Hematology,Urinalysis,
...[+2]
patent citation: 178
96
Lpath, Inc.
California, United States
Monoclonal antibody,Medical equipment,Lipidomics,
...[+2]
patent citation: 176
97
ICOS Corp.
Washington, United States
Biotechnology,Health care,Medicine,
...[+2]
patent citation: 173
98
Inhibrx LP
California, United States
Antibody,Immune activation,Oncology,
...[+2]
patent citation: 173
99
Synageva BioPharma Corp.
Massachusetts, United States
Botanical drug,Herb,Accelerated atherosclerosis,
...[+2]
patent citation: 171
100
Sanofi-Aventis U.S. LLC
New Jersey, United States
Manufacturing operations,Medicine,Health care,
...[+2]
patent citation: 170

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