Top 100 Key Players companies in Monoclonal antibody by Most Patent Citation in the United States in 2021 – Discovery

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The Monoclonal antibody top 100 is Discovery PatSnap’ annual ranking of the top 100 Most Patent Citation Monoclonal antibody Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2021, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell. Monoclonal antibodies can have monovalent affinity, in that they bind to the same epitope (the part of an antigen that is recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different plasma cell (antibody secreting immune cell) lineages. Bispecific monoclonal antibodies can also be engineered, by increasing the therapeutic targets of one single monoclonal antibody to two epitopes.

1	Genentech, Inc.	California, United States	Biotechnology,Biology,Medicine, ...[+2]	patent citation: 13,602
2	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	patent citation: 6,770
3	Bristol Myers Co.	New York, United States	Botanical drug,Herb	patent citation: 6,770
4	Medarex, Inc.	New Jersey, United States	Pharmacy and Therapeutics,Medical equipment,Biopharmaceutical, ...[+2]	patent citation: 4,780
5	Amgen Fremont, Inc.	California, United States	Monoclonal antibody therapy,Medicine,Monoclonal antibody	patent citation: 4,519
6	Biogen, Inc.	Massachusetts, United States	Neuroscience,Medicine,Health care, ...[+2]	patent citation: 4,388
7	Immunomedics, Inc.	New Jersey, United States	Biopharmaceutical,Medicine,Health care, ...[+2]	patent citation: 3,656
8	Abgenix, Inc.	California, United States	Antibody,Pharmacy and Therapeutics,Lead compound, ...[+2]	patent citation: 3,492
9	Massachusetts General Hospital	Massachusetts, United States	Substance abuse,Hospitality industry,Health care, ...[+2]	patent citation: 3,117
10	The General Hospital Corp.	Massachusetts, United States	Health care,Hospitality industry,Vascular Medicine, ...[+2]	patent citation: 3,117
11	Immunex Corp.	Washington, United States	Medicine,Health care,Leukemia, ...[+2]	patent citation: 2,369
12	STARTUP LFB USA, Inc.	Massachusetts, United States	Biotechnology,Drug,Medicine	patent citation: 2,154
13	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	patent citation: 2,122
14	Tanox Biosystems, Inc.	Texas, United States	Immune system,Biotechnology,Agriculture, ...[+2]	patent citation: 1,942
15	MacroGenics, Inc.	United States	Monoclonal antibody,Medicine,Health care, ...[+2]	patent citation: 1,760
16	Alexion Pharmaceuticals, Inc.	Connecticut, United States	Health care,Biopharmaceutical,Clinical trial, ...[+2]	patent citation: 1,695
17	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	patent citation: 1,665
18	Chiron Corp.	California, United States	Blood testing,Biology,Drug discovery, ...[+2]	patent citation: 1,646
19	Smithkline Beckman Corp	Pennsylvania, United States	Biotechnology,Medicine	patent citation: 1,537
20	Amgen, Inc.	California, United States	Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER, ...[+2]	patent citation: 1,408
21	Merck Sharp & Dohme Corp.	New Jersey, United States	Prescription drug,Medicine,Stroke, ...[+2]	patent citation: 1,293
22	Eli Lilly & Co.	Indiana, United States	Medicine,Health care,Humalog Mix, ...[+2]	patent citation: 1,181
23	Novartis Vaccines & Diagnostics, Inc.	New Jersey, United States	Health care,Medicine	patent citation: 1,164
24	Seagen Inc.	Washington, United States	Antibody-drug conjugate,Medicine,Health care, ...[+2]	patent citation: 1,161
25	Chimerix, Inc.	North Carolina, United States	Medicine,Health care,Virus, ...[+2]	patent citation: 1,158
26	ImClone LLC	New Jersey, United States	Bevacizumab,Medicine,Blood cell, ...[+2]	patent citation: 1,130
27	Cetus Corp.	California, United States	Botanical drug,Herb	patent citation: 1,118
28	Sigma-Aldrich, Inc.	Missouri, United States	Biotechnology,Biology,Chemical engineering, ...[+2]	patent citation: 1,092
29	Biogen MA, Inc.	Massachusetts, United States	Medicine,Drug,Developmental biology, ...[+2]	patent citation: 988
30	Boston Scientific Scimed, Inc.	Minnesota, United States	Medical equipment,Health care,Cloud computing, ...[+2]	patent citation: 977
31	Siemens Healthcare Diagnostics, Inc.	New York, United States	Vitro diagnostics,Health care,Picture archiving and communication system, ...[+2]	patent citation: 894
32	Epitomics, Inc.	California, United States	Monoclonal antibody,Medicine,Health care, ...[+2]	patent citation: 851
33	Schering Corp.	New Jersey, United States	Hepatitis,Medicine,Allergy	patent citation: 850
34	SEQUUS Pharmaceuticals, Inc.	California, United States	Biopharmaceutical,Oncology drugs,Clinical trial, ...[+1]	patent citation: 791
35	ZymoGenetics, Inc.	Washington, United States	Medicine,Pharmacy and Therapeutics,Protein chemistry, ...[+2]	patent citation: 770
36	Galaxy Biotech LLC	California, United States	Scientific literature,Biotechnology,Medicine, ...[+2]	patent citation: 694
37	Bayer HealthCare Pharmaceuticals, Inc.	New Jersey, United States	Medicine,Cardiovascular agent,Clinical trial, ...[+2]	patent citation: 678
38	Bayer Healthcare LLC	New Jersey, United States	Pharmaceutical medicine,Medicine,Computed tomography, ...[+2]	patent citation: 667
39	AbbVie Biotherapeutics, Inc.	Illinois, United States	Oncology drugs,Medicine,Oncology, ...[+2]	patent citation: 660
40	MedImmune LLC	Louisiana, United States	Medicine,Pharmacy and Therapeutics,Autoimmunity, ...[+2]	patent citation: 645
41	IDEC Pharmaceuticals Corp.	California, United States	Autoimmune disease,Health care,Apomorphine, ...[+2]	patent citation: 619
42	Regeneron Pharmaceuticals, Inc.	New York, United States	Monoclonal antibody,Clinical trial,Cholesterol, ...[+2]	patent citation: 574
43	Miles, Inc.	Kansas, United States	Mobile app,Chemical engineering	patent citation: 527
44	Celldex Therapeutics, Inc.	New Jersey, United States	Medicine,Health care,Immune system, ...[+2]	patent citation: 525
45	Vical, Inc.	California, United States	DNA,Biopharmaceutical,Gene delivery, ...[+2]	patent citation: 507
46	Genetic Systems Corp.	Washington, United States		patent citation: 495
47	Aventis Holdings, Inc.	Delaware, United States		patent citation: 492
48	Raven Biotechnologies, Inc.	California, United States	Health care,Pharmacy and Therapeutics,Biotechnology, ...[+2]	patent citation: 469
49	Morphotek, Inc.	Pennsylvania, United States	Monoclonal antibody,Antibody,Health care, ...[+2]	patent citation: 434
50	ARCH Development Corp.	District of Columbia, United States	Arch	patent citation: 426
51	Open Monoclonal Technology, Inc.	California, United States	Medicine,Genetic engineering,Antibody, ...[+2]	patent citation: 424
52	Washington Research Foundation	Washington, United States	Physical science,Mobile device,Gene delivery, ...[+2]	patent citation: 416
53	The Dow Chemical Co.	Michigan, United States	Coating,Agriculture,Chemical engineering, ...[+2]	patent citation: 414
54	XOMA Corp.	California, United States	Antibody,Software development,Medicine, ...[+2]	patent citation: 406
55	Celtrix Pharmaceuticals, Inc.	California, United States	Generic prescription drug,Medicine,Prescription drug, ...[+1]	patent citation: 406
56	Streck Laboratories International, Inc.	Nebraska, United States		patent citation: 406
57	Rise Technology, Inc.	Massachusetts, United States	Electronic component,Computer hardware,Electronics, ...[+1]	patent citation: 402
58	Roche Diagnostics Corp.	Indiana, United States	Medicine,Urinalysis,Immunoassay, ...[+2]	patent citation: 399
59	Eisai, Inc.	New Jersey, United States	Health care,Medicine,Managed care, ...[+2]	patent citation: 391
60	UAB Research Foundation	Alabama, United States	Biotechnology,Agriculture,Fishery, ...[+2]	patent citation: 383
61	Xenerex Biosciences	California, United States	Antigen,Antibody	patent citation: 377
62	Boehringer Ingelheim Pharmaceuticals, Inc.	Connecticut, United States	Central nervous system,Medicine,Drug, ...[+2]	patent citation: 372
63	Protein Design Labs, Inc.	California, United States	E-commerce,Supply chain management,Turnkey	patent citation: 361
64	Rinat Neuroscience Corp.	California, United States	Neuroscience,Antibody,Medicine, ...[+2]	patent citation: 353
65	Vaccinex, Inc.	New York, United States	Antibody,Medicine,Health care, ...[+2]	patent citation: 330
66	Genzyme Corp.	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,Multiple sclerosis, ...[+2]	patent citation: 322
67	Regents of the University of California	California, United States	Working capital,Pathology,Companion diagnostic, ...[+2]	patent citation: 310
68	Scripps Clinic & Research Foundation	California, United States		patent citation: 303
69	AbbVie, Inc.	Illinois, United States	Health care,Medicine,Biopharmaceutical, ...[+2]	patent citation: 287
70	AVEO Pharmaceuticals, Inc.	Massachusetts, United States	Biopharmaceutical,Medicine,Health care, ...[+2]	patent citation: 283
71	Elan Pharmaceuticals, LLC	Michigan, United States	Autoimmune disease,Medicine,Enzyme, ...[+2]	patent citation: 277
72	CytImmune Sciences, Inc.	United States	Pharmaceutical industry,Health care,Nanomedicine, ...[+2]	patent citation: 268
73	G.D. Searle LLC	Illinois, United States		patent citation: 268
74	Morphogenesis, Inc.	United States	Health care,Pharmacy and Therapeutics,Gene, ...[+2]	patent citation: 264
75	Bayer Pharmaceuticals Corp.	Pennsylvania, United States		patent citation: 262
76	Beckman Instruments, Inc.	Indiana, United States	Medicine,Guidance system	patent citation: 248
77	Genetastix Corp.	California, United States		patent citation: 241
78	STARTUP Precision Biologics, Inc.	Texas, United States	Cancer vaccine,Pharmacy and Therapeutics,Biotechnology, ...[+2]	patent citation: 238
79	QHSLab, Inc.	New York, United States	Health care,Chronic care,Remote patient monitoring, ...[+2]	patent citation: 226
80	Lexicon Pharmaceuticals, Inc.	Texas, United States	Health care,Clinical trial,Medicine, ...[+2]	patent citation: 220
81	Sunol Molecular Corp.	United States	Tissue factor,Medicine	patent citation: 215
82	OSI Pharmaceuticals, Inc.	New York, United States	Medicine,Health care,Software development, ...[+2]	patent citation: 213
83	Repligen Corp.	Massachusetts, United States	Chromatography,Fast-moving consumer goods,Protein A, ...[+2]	patent citation: 207
84	Apexigen America, Inc.	California, United States	Medicine,Health care,Antibody, ...[+2]	patent citation: 204
85	Pharmacia & Upjohn Co. LLC	Michigan, United States	Drug	patent citation: 202
86	Genetics Institute LLC	United States	Medicine,Health care,Biotechnology, ...[+2]	patent citation: 196
87	Provention Bio, Inc.	New Jersey, United States	Medicine,Health care,Biopharmaceutical, ...[+2]	patent citation: 193
88	Baxter International, Inc.	Illinois, United States	Clinical trial,Drug,Hemodialysis, ...[+2]	patent citation: 192
89	Arch Oncology, Inc.	California, United States	Antibody,Cardiovascular agent,Clinical trial, ...[+2]	patent citation: 192
90	STARTUP SyntheX, Inc.	California, United States	Biology,Medicine,Pharmacy and Therapeutics, ...[+2]	patent citation: 188
91	Research Development Foundation	United States	Plasmid,Molecular medicine,Cardiovascular agent, ...[+2]	patent citation: 187
92	Human Genome Sciences, Inc.	United States	Medicine,Health care,Biopharmaceutical, ...[+2]	patent citation: 186
93	Trustees of Dartmouth College	New Hampshire, United States	Asset management,Impact investing	patent citation: 182
94	Aegis Therapeutics LLC	California, United States	Medicine,Biotechnology,Clobazam, ...[+2]	patent citation: 182
95	Beckman Coulter, Inc.	California, United States	Medical equipment,Hematology,Urinalysis, ...[+2]	patent citation: 178
96	Lpath, Inc.	California, United States	Monoclonal antibody,Medical equipment,Lipidomics, ...[+2]	patent citation: 176
97	ICOS Corp.	Washington, United States	Biotechnology,Health care,Medicine, ...[+2]	patent citation: 173
98	Inhibrx LP	California, United States	Antibody,Immune activation,Oncology, ...[+2]	patent citation: 173
99	Synageva BioPharma Corp.	Massachusetts, United States	Botanical drug,Herb,Accelerated atherosclerosis, ...[+2]	patent citation: 171
100	Sanofi-Aventis U.S. LLC	New Jersey, United States	Manufacturing operations,Medicine,Health care, ...[+2]	patent citation: 170