Top 100 Key Players companies in Monoclonal antibody by Most Patent Filings in the United States in 2022 – Discovery

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The Monoclonal antibody top 100 is Discovery PatSnap’ annual ranking of the top 100 Most Patent Filings Monoclonal antibody Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2022, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell. Monoclonal antibodies can have monovalent affinity, in that they bind to the same epitope (the part of an antigen that is recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different plasma cell (antibody secreting immune cell) lineages. Bispecific monoclonal antibodies can also be engineered, by increasing the therapeutic targets of one single monoclonal antibody to two epitopes.

1	Genentech, Inc.	California, United States	Biotechnology,Biology,Medicine, ...[+2]	Patent: 748
2	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	Patent: 471
3	Bristol Myers Co.	New York, United States	Botanical drug,Herb	Patent: 471
4	Medarex, Inc.	New Jersey, United States	Pharmacy and Therapeutics,Medical equipment,Biopharmaceutical, ...[+2]	Patent: 422
5	Amgen, Inc.	California, United States	Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER, ...[+2]	Patent: 319
6	Amgen Fremont, Inc.	California, United States	Monoclonal antibody therapy,Medicine,Monoclonal antibody	Patent: 309
7	Regeneron Pharmaceuticals, Inc.	New York, United States	Monoclonal antibody,Clinical trial,Cholesterol, ...[+2]	Patent: 298
8	Eli Lilly & Co.	Indiana, United States	Medicine,Health care,Humalog Mix, ...[+2]	Patent: 277
9	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	Patent: 268
10	Biogen MA, Inc.	Massachusetts, United States	Medicine,Drug,Developmental biology, ...[+2]	Patent: 256
11	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	Patent: 235
12	Bayer Healthcare LLC	New Jersey, United States	Pharmaceutical medicine,Medicine,Computed tomography, ...[+2]	Patent: 217
13	ZymoGenetics, Inc.	Washington, United States	Medicine,Pharmacy and Therapeutics,Protein chemistry, ...[+2]	Patent: 198
14	Merck Sharp & Dohme Corp.	New Jersey, United States	Prescription drug,Medicine,Stroke, ...[+2]	Patent: 196
15	AbbVie, Inc.	Illinois, United States	Health care,Medicine,Biopharmaceutical, ...[+2]	Patent: 193
16	MedImmune LLC	Louisiana, United States	Medicine,Pharmacy and Therapeutics,Autoimmunity, ...[+2]	Patent: 162
17	Smithkline Beckman Corp	Pennsylvania, United States	Biotechnology,Medicine	Patent: 157
18	Boehringer Ingelheim Pharmaceuticals, Inc.	Connecticut, United States	Central nervous system,Medicine,Drug, ...[+2]	Patent: 157
19	Immunex Corp.	Washington, United States	Medicine,Health care,Leukemia, ...[+2]	Patent: 155
20	Schering Corp.	New Jersey, United States	Hepatitis,Medicine,Allergy	Patent: 142
21	Abgenix, Inc.	California, United States	Antibody,Pharmacy and Therapeutics,Lead compound, ...[+2]	Patent: 130
22	Chiron Corp.	California, United States	Blood testing,Biology,Drug discovery, ...[+2]	Patent: 129
23	Galaxy Biotech LLC	California, United States	Scientific literature,Biotechnology,Medicine, ...[+2]	Patent: 125
24	Celldex Therapeutics, Inc.	New Jersey, United States	Medicine,Health care,Immune system, ...[+2]	Patent: 122
25	Immunomedics, Inc.	New Jersey, United States	Biopharmaceutical,Medicine,Health care, ...[+2]	Patent: 118
26	Novartis Vaccines & Diagnostics, Inc.	New Jersey, United States	Health care,Medicine	Patent: 113
27	Tanox Biosystems, Inc.	Texas, United States	Immune system,Biotechnology,Agriculture, ...[+2]	Patent: 111
28	Rinat Neuroscience Corp.	California, United States	Neuroscience,Antibody,Medicine, ...[+2]	Patent: 109
29	Lpath, Inc.	California, United States	Monoclonal antibody,Medical equipment,Lipidomics, ...[+2]	Patent: 105
30	Biogen, Inc.	Massachusetts, United States	Neuroscience,Medicine,Health care, ...[+2]	Patent: 103
31	Massachusetts General Hospital	Massachusetts, United States	Substance abuse,Hospitality industry,Health care, ...[+2]	Patent: 103
32	The General Hospital Corp.	Massachusetts, United States	Health care,Hospitality industry,Vascular Medicine, ...[+2]	Patent: 103
33	Scripps Clinic & Research Foundation	California, United States		Patent: 102
34	Genetic Systems Corp.	Washington, United States		Patent: 98
35	Roche Diagnostics Corp.	Indiana, United States	Medicine,Urinalysis,Immunoassay, ...[+2]	Patent: 94
36	Regents of the University of California	California, United States	Working capital,Pathology,Companion diagnostic, ...[+2]	Patent: 93
37	Apexigen America, Inc.	California, United States	Medicine,Health care,Antibody, ...[+2]	Patent: 91
38	Vaccinex, Inc.	New York, United States	Antibody,Medicine,Health care, ...[+2]	Patent: 87
39	MacroGenics, Inc.	United States	Monoclonal antibody,Medicine,Health care, ...[+2]	Patent: 80
40	AVEO Pharmaceuticals, Inc.	Massachusetts, United States	Biopharmaceutical,Medicine,Health care, ...[+2]	Patent: 79
41	ImClone LLC	New Jersey, United States	Bevacizumab,Medicine,Blood cell, ...[+2]	Patent: 75
42	Omeros Corp.	Washington, United States	Medicine,Health care,Central nervous system, ...[+2]	Patent: 73
43	Zoetis Services LLC	New Jersey, United States	Drug,Medicine,Vertical farming, ...[+2]	Patent: 70
44	Cetus Corp.	California, United States	Botanical drug,Herb	Patent: 69
45	Bayer HealthCare Pharmaceuticals, Inc.	New Jersey, United States	Medicine,Cardiovascular agent,Clinical trial, ...[+2]	Patent: 69
46	Research Development Foundation	United States	Plasmid,Molecular medicine,Cardiovascular agent, ...[+2]	Patent: 66
47	Wyeth LLC	New Jersey, United States		Patent: 64
48	Genzyme Corp.	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,Multiple sclerosis, ...[+2]	Patent: 62
49	Alexion Pharmaceuticals, Inc.	Connecticut, United States	Health care,Biopharmaceutical,Clinical trial, ...[+2]	Patent: 61
50	Merrimack Pharmaceuticals, Inc.	Massachusetts, United States	Health care,Autoimmunity,Medicine, ...[+2]	Patent: 61
51	Saladax Biomedical, Inc.	Pennsylvania, United States	Assay,Health care,Blood Collection Tube, ...[+2]	Patent: 60
52	American Can Co.	United States	Tin can,Packaging engineering,Microservices, ...[+1]	Patent: 60
53	ImmunoGen, Inc.	Massachusetts, United States	Medicine,Health care,Pharmacy and Therapeutics, ...[+2]	Patent: 59
54	Miles, Inc.	Kansas, United States	Mobile app,Chemical engineering	Patent: 59
55	Trellis Bioscience, Inc.	California, United States	Health care,Pharmacy and Therapeutics,Biotechnology, ...[+2]	Patent: 55
56	Raven Biotechnologies, Inc.	California, United States	Health care,Pharmacy and Therapeutics,Biotechnology, ...[+2]	Patent: 55
57	IDEC Pharmaceuticals Corp.	California, United States	Autoimmune disease,Health care,Apomorphine, ...[+2]	Patent: 54
58	Arch Oncology, Inc.	California, United States	Antibody,Cardiovascular agent,Clinical trial, ...[+2]	Patent: 52
59	TriPath Imaging, Inc.	North Carolina, United States	Cervical cytology screening,Medicine,Health care, ...[+2]	Patent: 51
60	La Jolla Institute for Allergy & Immunology	California, United States	Immune system,Health care,Biomedicine, ...[+2]	Patent: 51
61	Theraclone Sciences, Inc.	Washington, United States	Monoclonal antibody,Health care,Pharmacy and Therapeutics, ...[+2]	Patent: 51
62	Medimmune, Inc.	United States	Botanical drug,Herb	Patent: 50
63	Morphotek, Inc.	Pennsylvania, United States	Monoclonal antibody,Antibody,Health care, ...[+2]	Patent: 49
64	UAB Research Foundation	Alabama, United States	Biotechnology,Agriculture,Fishery, ...[+2]	Patent: 48
65	QHSLab, Inc.	New York, United States	Health care,Chronic care,Remote patient monitoring, ...[+2]	Patent: 47
66	Siemens Healthcare Diagnostics, Inc.	New York, United States	Vitro diagnostics,Health care,Picture archiving and communication system, ...[+2]	Patent: 47
67	STARTUP Precision Biologics, Inc.	Texas, United States	Cancer vaccine,Pharmacy and Therapeutics,Biotechnology, ...[+2]	Patent: 46
68	DowElanco Ltd.	United States	Chemical engineering,Agriculture,Pest control	Patent: 46
69	ICOS Corp.	Washington, United States	Biotechnology,Health care,Medicine, ...[+2]	Patent: 45
70	Seagen Inc.	Washington, United States	Antibody-drug conjugate,Medicine,Health care, ...[+2]	Patent: 44
71	REGENXBIO, Inc.	United States	Gene delivery,Viral vector,Pharmacy and Therapeutics, ...[+2]	Patent: 44
72	Schering Biotech Corp.	United States		Patent: 43
73	Lexicon Pharmaceuticals, Inc.	Texas, United States	Health care,Clinical trial,Medicine, ...[+2]	Patent: 42
74	Alector, Inc.	California, United States	Health care,Pharmacy and Therapeutics,Antibody, ...[+2]	Patent: 42
75	Eisai, Inc.	New Jersey, United States	Health care,Medicine,Managed care, ...[+2]	Patent: 42
76	bioMérieux, Inc.	North Carolina, United States	Medicine,Nucleic acid test,Blood Screening, ...[+2]	Patent: 42
77	EMD Millipore Corp.	Massachusetts, United States	Biotechnology,Biology,Medicine, ...[+2]	Patent: 41
78	E.I. du Pont de Nemours & Co.	Delaware, United States	Agriculture,Materials science,Electronics, ...[+2]	Patent: 39
79	Beckman Instruments, Inc.	Indiana, United States	Medicine,Guidance system	Patent: 39
80	Progenics Pharmaceuticals, Inc.	New York, United States	Medicine,Biopharmaceutical,Methylnaltrexone Bromide, ...[+2]	Patent: 39
81	Inhibitex LLC	United States	Medicine,Health care,Biopharmaceutical, ...[+2]	Patent: 39
82	Washington Research Foundation	Washington, United States	Physical science,Mobile device,Gene delivery, ...[+2]	Patent: 38
83	Inhibrx, Inc.	California, United States	Biotechnology,Protein engineering,Orphan diseases, ...[+2]	Patent: 37
84	Dyax Corp.	Massachusetts, United States	Biopharmaceutical,Monoclonal antibody,Medicine, ...[+2]	Patent: 35
85	Baxter International, Inc.	Illinois, United States	Clinical trial,Drug,Hemodialysis, ...[+2]	Patent: 33
86	Apollo Endosurgery, Inc.	Texas, United States	Medical equipment,Health care,Gastric balloon, ...[+2]	Patent: 33
87	BioAtla, Inc.	California, United States	Health care,Monoclonal antibody,Drug, ...[+2]	Patent: 33
88	Scholar Rock Holding Corp.	Massachusetts, United States	Growth factor,Health care,Pharmacy and Therapeutics, ...[+2]	Patent: 32
89	Scholar Rock, Inc.	Massachusetts, United States	Biotechnology,Spinal muscular atrophy,Growth factor, ...[+2]	Patent: 32
90	Bio-Rad Laboratories, Inc.	California, United States	Medicine,Proteomics,Genomics, ...[+2]	Patent: 31
91	CytoDyn, Inc.	Washington, United States	Medicine,Pharmacy and Therapeutics,Virus, ...[+2]	Patent: 31
92	Epitomics, Inc.	California, United States	Monoclonal antibody,Medicine,Health care, ...[+2]	Patent: 31
93	Rise Technology, Inc.	Massachusetts, United States	Electronic component,Computer hardware,Electronics, ...[+1]	Patent: 31
94	Beckman Coulter, Inc.	California, United States	Medical equipment,Hematology,Urinalysis, ...[+2]	Patent: 30
95	STARTUP Verseau Therapeutics, Inc.	Massachusetts, United States	Pharmacy and Therapeutics,Oncology drugs,Biopharmaceutical, ...[+2]	Patent: 29
96	The Dow Chemical Co.	Michigan, United States	Coating,Agriculture,Chemical engineering, ...[+2]	Patent: 28
97	United Biomedical, Inc.	New York, United States	Medicine,Coronavirus disease 2019 (COVID-19),Renal anemia, ...[+2]	Patent: 28
98	Actinium Pharmaceuticals, Inc.	New York, United States	Medicine,Health care,Bone marrow, ...[+2]	Patent: 27
99	Mersana Therapeutics, Inc.	Massachusetts, United States	Biodegradable polymer,Medicine,Health care, ...[+2]	Patent: 27
100	STARTUP Dragonfly Therapeutics, Inc.	Massachusetts, United States	Pharmacy and Therapeutics,Biomedicine,Biotechnology, ...[+2]	Patent: 27