Top 100 Key Players companies in Plasmid by Highest Patent Value in the world in 2019 – Discovery

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The Plasmid top 100 is Discovery PatSnap’ annual ranking of the top 100 Highest Patent Value Plasmid Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2019, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

A plasmid is a small DNA molecule within a cell that is physically separated from chromosomal DNA and can replicate independently. They are most commonly found as small circular, double-stranded DNA molecules in bacteria; however, plasmids are sometimes present in archaea and eukaryotic organisms. In nature, plasmids often carry genes that benefit the survival of the organism, such as by providing antibiotic resistance. While the chromosomes are big and contain all the essential genetic information for living under normal conditions, plasmids usually are very small and contain only additional genes that may be useful in certain situations or conditions. Artificial plasmids are widely used as vectors in molecular cloning, serving to drive the replication of recombinant DNA sequences within host organisms. In the laboratory, plasmids may be introduced into a cell via transformation.

1	TerraVia Holdings, Inc.	California, United States	Biofuel,Chemical engineering,Algae, ...[+2]	Avg patent value: 9.22 M
2	GeneWEAVE	California, United States	Clinical trial,Antibiotic Stewardship,Drug resistance, ...[+2]	Avg patent value: 8.89 M
3	GeneWeave Biosciences, Inc.	California, United States	In vitro,Health care,Molecular systems, ...[+1]	Avg patent value: 8.89 M
4	ImmunoGen, Inc.	Massachusetts, United States	Medicine,Health care,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 8.73 M
5	Ferring BV	Noord-Holland, Netherlands	Gastroenterology,Viscosupplementation,Infertility, ...[+2]	Avg patent value: 8.68 M
6	Caribou Biosciences, Inc.	California, United States	Health care,Pharmacy and Therapeutics,Cellular engineering, ...[+2]	Avg patent value: 8.51 M
7	GlaxoSmithKline Biologicals SA	Belgium	Medicine,Rubella,Hepatitis, ...[+2]	Avg patent value: 8.38 M
8	Grifols Therapeutics, Inc.	North Carolina, United States	Congenital afibrinogenemia,Medicine,Fibrinogen, ...[+1]	Avg patent value: 8.08 M
9	Amgen Research (Munich) GmbH	Hessen, Germany	Metal powder,Metal	Avg patent value: 7.73 M
10	Janssen Pharmaceuticals, Inc.	New Jersey, United States	Drug,Medicine,Risperdal Consta, ...[+2]	Avg patent value: 7.29 M
11	Arbutus Biopharma Corp.	British Columbia, Canada	Medicine,Health care,Drug, ...[+2]	Avg patent value: 7.22 M
12	MedImmune Ltd.	Cambridgeshire, United Kingdom	Molecular engineering,Medicine	Avg patent value: 7.15 M
13	ProBioGen AG	Berlin, Germany	Biopharmaceutical,Monoclonal antibody,Manufacturing organization, ...[+2]	Avg patent value: 6.84 M
14	Touchlight Genetics Ltd.	Shropshire, United Kingdom	Health care,Gene delivery,Drug development, ...[+2]	Avg patent value: 6.32 M
15	Bioriginal Food & Science Corp.	Saskatchewan, Canada	Linseed oil,Medicine,Health care, ...[+2]	Avg patent value: 6.30 M
16	AC Immune SA	Vaud, Switzerland	Pharmacy and Therapeutics,Medicine,Biomedicine, ...[+2]	Avg patent value: 6.23 M
17	Meiji Seika Kaisha Ltd.	Tokyo, Japan	Veterinary medicine,Food industry,Snack foods, ...[+1]	Avg patent value: 6.18 M
18	Meiji Seika Pharma Co., Ltd.	Tokyo, Japan	Clinical trial,Drug,Medicine, ...[+2]	Avg patent value: 6.18 M
19	X4 Pharmaceuticals (Austria) GmbH	Austria		Avg patent value: 6.18 M
20	Amgen, Inc.	California, United States	Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER, ...[+2]	Avg patent value: 6.10 M
21	Octapharma AG	Schwyz, Switzerland	Medicine,Health care,Collective responsibility, ...[+2]	Avg patent value: 5.78 M
22	Zoetis Services LLC	New Jersey, United States	Drug,Medicine,Vertical farming, ...[+2]	Avg patent value: 5.77 M
23	Kirin-Amgen, Inc.	California, United States	Pharmaceutical drug,Medicine	Avg patent value: 5.77 M
24	Beijing Sannuo Jiayi Biotechnology Co. Ltd.	Beijing Shi, China		Avg patent value: 5.72 M
25	Bavarian Nordic A/S	Hovedstaden, Denmark	Cancer immunotherapy,Health care,Medicine, ...[+2]	Avg patent value: 5.66 M
26	Bavarian Nordic, Inc.	North Carolina, United States	Drug,Medicine	Avg patent value: 5.66 M
27	Ramot at Tel Aviv University Ltd.	Tel Aviv, Israel	Technology transfer,Industrial engineering,Biophysics, ...[+2]	Avg patent value: 5.61 M
28	cCAM Biotherapeutics Ltd.	HaZafon, Israel	Medicine,Clinical trial,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 5.61 M
29	ChromaGenics BV	Noord-Holland, Netherlands	Chromatin,Biochemistry,Health care, ...[+1]	Avg patent value: 5.50 M
30	EnGeneIC Molecular Delivery Pty Ltd.	Australia		Avg patent value: 5.48 M
31	FUJIFILM Diosynth Biotechnologies UK Ltd.	Stockton-on-Tees, United Kingdom	Medicine,Cell,Manufacturing organization, ...[+2]	Avg patent value: 5.32 M
32	Dyax Corp.	Massachusetts, United States	Biopharmaceutical,Monoclonal antibody,Medicine, ...[+2]	Avg patent value: 5.29 M
33	Athera Biotechnologies AB	Sweden	Medicine,Companion diagnostic,Cardiovascular agent, ...[+2]	Avg patent value: 5.29 M
34	AM-Pharma Holding BV	Utrecht, Netherlands	Health care,Peptide,Biomedicine, ...[+2]	Avg patent value: 5.00 M
35	AM-Pharma BV	Utrecht, Netherlands	Acute kidney injury,Clinical trial,Medicine, ...[+2]	Avg patent value: 5.00 M
36	Snipr Technologies Ltd.	United Kingdom		Avg patent value: 4.88 M
37	Themis Bioscience GmbH	Wien, Austria	Biotechnology,Clinical trial,Health care, ...[+2]	Avg patent value: 4.81 M
38	Butamax Advanced Biofuels LLC	Delaware, United States	Biofuel,Renewable energy,Medicine, ...[+2]	Avg patent value: 4.73 M
39	Seraxis, Inc.	United States	Endocrinology	Avg patent value: 4.63 M
40	Novartis AG	Basel-Stadt, Switzerland	Dosage form,Health care,Medicine, ...[+2]	Avg patent value: 4.61 M
41	Theravectys SAS	Île-de-France, France	Health care,Cancer,Gene delivery, ...[+2]	Avg patent value: 4.61 M
42	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	Avg patent value: 4.61 M
43	EpiVax, Inc.	Rhode Island, United States	Immunogenicity,Medicine,Computational immunology, ...[+2]	Avg patent value: 4.52 M
44	Advanced Accelerator Applications SA	Rhône-Alpes, France	Radioligand,Nuclear medicine,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 4.41 M
45	Dompé SpA	L'Aquila, Italy	Eye drop,Medicine,Otorhinolaryngology, ...[+2]	Avg patent value: 4.41 M
46	NIPPI Corp.	Kanagawa, Japan	Aerospace,Rocket,National security	Avg patent value: 4.38 M
47	Xalud Therapeutics, Inc.	New York, United States	Amyotrophic lateral sclerosis,Neuroscience,Health care, ...[+2]	Avg patent value: 4.36 M
48	DowElanco Ltd.	United States	Chemical engineering,Agriculture,Pest control	Avg patent value: 4.34 M
49	Anaeropharma Science, Inc.	Tokyo, Japan	Bifidobacterium,Pharmacy and Therapeutics,Medicine, ...[+2]	Avg patent value: 4.32 M
50	Ranbaxy Laboratories Ltd.	Haryana, India	Health care,Drug,Active ingredient, ...[+2]	Avg patent value: 4.24 M
51	Indena SpA	Lombardia, Italy	Medicine,Health care,Flavonoid, ...[+2]	Avg patent value: 4.24 M
52	Bayer Technology Services GmbH	Nordrhein-Westfalen, Germany	Construction engineering,Plant management,Fluid catalytic cracking, ...[+2]	Avg patent value: 4.24 M
53	MolMed	Lombardia, Italy	Cell therapy,Genomics,Epithelial tumour, ...[+2]	Avg patent value: 4.24 M
54	Koninklijke DSM NV	Netherlands	Animal nutrition,Health care,Biology, ...[+2]	Avg patent value: 4.23 M
55	STARTUP 2-BBB Medicines BV	Zuid-Holland, Netherlands	Drug,Health care	Avg patent value: 4.20 M
56	PsiOxus Therapeutics Ltd.	Oxfordshire, United Kingdom	Gene,Medicine,Health care, ...[+2]	Avg patent value: 4.14 M
57	Regeneron Pharmaceuticals, Inc.	New York, United States	Monoclonal antibody,Clinical trial,Cholesterol, ...[+2]	Avg patent value: 4.09 M
58	Esteve Pharmaceuticals S.A.	Cataluña, Spain	Ophthalmology,Pathology,Pharmacy, ...[+2]	Avg patent value: 4.07 M
59	ESTEVE	Cataluña, Spain	Drug,Medicine,Health care, ...[+2]	Avg patent value: 4.07 M
60	Virginia Tech Intellectual Properties, Inc.	Virginia, United States	Software,Medical imaging,Digital library, ...[+2]	Avg patent value: 4.06 M
61	Bayer AG	Nordrhein-Westfalen, Germany	Health care,Biology,Chemical engineering, ...[+2]	Avg patent value: 3.89 M
62	Bayer Oy	Finland		Avg patent value: 3.89 M
63	Pierre Fabre Dermatologie SAS	Île-de-France, France	Medicine,Clinical trial,Biomedicine, ...[+2]	Avg patent value: 3.88 M
64	STARTUP Ilya Pharma AB	Sweden	Biological drugs,Health care,Drug, ...[+2]	Avg patent value: 3.81 M
65	Bayer Intellectual Property GmbH	Nordrhein-Westfalen, Germany		Avg patent value: 3.80 M
66	Vaximm AG	Basel-Stadt, Switzerland	Tumor vasculature,Software development,Medicine, ...[+2]	Avg patent value: 3.72 M
67	Alfasigma SpA	Emilia-Romagna, Italy	Internationalization,Gastrointestinal agent,Clinical trial, ...[+2]	Avg patent value: 3.71 M
68	DuPont Nutrition Biosciences ApS	Hovedstaden, Denmark	Food science,Medicine,Health care, ...[+2]	Avg patent value: 3.70 M
69	Minaris Medical Co., Ltd.	Tokyo, Japan	Medicine,Vitro diagnostics,Immunoprotein, ...[+2]	Avg patent value: 3.66 M
70	BASF Plant Science LLC	New Jersey, United States	Starch,Fertilizer,Plant science	Avg patent value: 3.55 M
71	Laboratorios LETI SL	Cataluña, Spain	Allergy drugs,Dermatology,Oncology, ...[+2]	Avg patent value: 3.54 M
72	Æterna Zentaris, Inc.	Quebec, Canada	Health care,Medicine,Clinical trial, ...[+2]	Avg patent value: 3.53 M
73	Intervet International BV	Noord-Brabant, Netherlands	Fertility management,Medicine,Feed additive	Avg patent value: 3.44 M
74	Seek Ltd. (UK)	United Kingdom	Over-the-counter	Avg patent value: 3.32 M
75	Aeras Global TB Vaccine Foundation	United States	Tuberculosis vaccines,Toxoid,DNA vaccination, ...[+2]	Avg patent value: 3.32 M
76	Genentech, Inc.	California, United States	Biotechnology,Biology,Medicine, ...[+2]	Avg patent value: 3.31 M
77	Bayer Animal Health GmbH	Bayern, Germany	Antimicrobial,Zoonosis,Medicine, ...[+2]	Avg patent value: 3.31 M
78	Sangamo Therapeutics, Inc.	California, United States	Cell,Pharmacy and Therapeutics,Genomics, ...[+2]	Avg patent value: 3.29 M
79	TOSHIBA Corp.	Tokyo, Japan	Semiconductor,Computer hardware,Electronics, ...[+2]	Avg patent value: 3.26 M
80	Canon Medical Systems Corp.	Tochigi, Japan	X-ray,Medical imaging,Medicine, ...[+2]	Avg patent value: 3.26 M
81	Toshiba Medical Systems Co. Ltd.	Malaysia	Digital imaging,Medical equipment,Medicine	Avg patent value: 3.26 M
82	STARTUP EveliQure Biotechnologies GmbH	Wien, Austria	Bacillary dysentery,Biology,Diarrheal diseases, ...[+2]	Avg patent value: 3.23 M
83	Athenix Corp.	North Carolina, United States	Insect,Agriculture,Chemical engineering, ...[+2]	Avg patent value: 3.22 M
84	RPH Pharmaceuticals AB	SE	Medicine	Avg patent value: 3.19 M
85	Transgene SA	Alsace, France	Immunotherapy,Transgene,Medicine, ...[+2]	Avg patent value: 3.12 M
86	Pfizer Products, Inc.	Connecticut, United States		Avg patent value: 3.09 M
87	Bayer HealthCare Pharmaceuticals, Inc.	New Jersey, United States	Medicine,Cardiovascular agent,Clinical trial, ...[+2]	Avg patent value: 2.97 M
88	Pierre Fabre Médicament SAS	Île-de-France, France	Oncology,Cosmetics,Pharmacy, ...[+1]	Avg patent value: 2.94 M
89	Cellivery Therapeutics, Inc.	South Korea	Enzyme,Health care,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 2.92 M
90	Algenex SL	Madrid, Spain	Diagnostic Reagent,Molecule,Gene, ...[+1]	Avg patent value: 2.92 M
91	XOMA Technology Ltd.	Bermuda	Medicine	Avg patent value: 2.92 M
92	Viromed, Inc.	Minnesota, United States	Medical laboratory,Health care	Avg patent value: 2.92 M
93	MedImmune Vaccines, Inc.	United States	Virus,Physical fitness,Health care, ...[+1]	Avg patent value: 2.91 M
94	Cobra Biologics Ltd.	Stoke-on-Trent, United Kingdom	Clinical trial,Biology,Monoclonal antibody, ...[+2]	Avg patent value: 2.90 M
95	Minomic International Ltd.	Isabela, Philippines	Prostate cancer,Medicine,Monoclonal antibody, ...[+2]	Avg patent value: 2.89 M
96	Wyeth LLC	New Jersey, United States		Avg patent value: 2.75 M
97	Clarient, Inc.	California, United States	Health care,Companion diagnostic,Standard of care, ...[+2]	Avg patent value: 2.73 M
98	Aventis Pharma	Belgium		Avg patent value: 2.71 M
99	STARTUP Azotic Technologies Ltd.	Lancashire, United Kingdom	Nitrogen,Farming industry,Gluconacetobacter	Avg patent value: 2.64 M
100	AB Enzymes GmbH	Hessen, Germany	Enzyme,Chemical engineering,Textile, ...[+2]	Avg patent value: 2.64 M