Top 100 Key Players companies in Plasmid by Highest Patent Value in the United States in 2018 – Discovery

Free Trial

The Plasmid top 100 is Discovery PatSnap’ annual ranking of the top 100 Highest Patent Value Plasmid Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2018, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

A plasmid is a small DNA molecule within a cell that is physically separated from chromosomal DNA and can replicate independently. They are most commonly found as small circular, double-stranded DNA molecules in bacteria; however, plasmids are sometimes present in archaea and eukaryotic organisms. In nature, plasmids often carry genes that benefit the survival of the organism, such as by providing antibiotic resistance. While the chromosomes are big and contain all the essential genetic information for living under normal conditions, plasmids usually are very small and contain only additional genes that may be useful in certain situations or conditions. Artificial plasmids are widely used as vectors in molecular cloning, serving to drive the replication of recombinant DNA sequences within host organisms. In the laboratory, plasmids may be introduced into a cell via transformation.

1	TerraVia Holdings, Inc.	California, United States	Biofuel,Chemical engineering,Algae, ...[+2]	Avg patent value: 9.22 M
2	GeneWEAVE	California, United States	Clinical trial,Antibiotic Stewardship,Drug resistance, ...[+2]	Avg patent value: 8.89 M
3	GeneWeave Biosciences, Inc.	California, United States	In vitro,Health care,Molecular systems, ...[+1]	Avg patent value: 8.89 M
4	ImmunoGen, Inc.	Massachusetts, United States	Medicine,Health care,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 8.73 M
5	Caribou Biosciences, Inc.	California, United States	Health care,Pharmacy and Therapeutics,Cellular engineering, ...[+2]	Avg patent value: 8.51 M
6	Grifols Therapeutics, Inc.	North Carolina, United States	Congenital afibrinogenemia,Medicine,Fibrinogen, ...[+1]	Avg patent value: 8.08 M
7	Janssen Pharmaceuticals, Inc.	New Jersey, United States	Drug,Medicine,Risperdal Consta, ...[+2]	Avg patent value: 7.29 M
8	Amgen, Inc.	California, United States	Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER, ...[+2]	Avg patent value: 6.10 M
9	Zoetis Services LLC	New Jersey, United States	Drug,Medicine,Vertical farming, ...[+2]	Avg patent value: 5.77 M
10	Kirin-Amgen, Inc.	California, United States	Pharmaceutical drug,Medicine	Avg patent value: 5.77 M
11	Bavarian Nordic, Inc.	North Carolina, United States	Drug,Medicine	Avg patent value: 5.66 M
12	Dyax Corp.	Massachusetts, United States	Biopharmaceutical,Monoclonal antibody,Medicine, ...[+2]	Avg patent value: 5.29 M
13	Butamax Advanced Biofuels LLC	Delaware, United States	Biofuel,Renewable energy,Medicine, ...[+2]	Avg patent value: 4.73 M
14	Seraxis, Inc.	United States	Endocrinology	Avg patent value: 4.63 M
15	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	Avg patent value: 4.61 M
16	EpiVax, Inc.	Rhode Island, United States	Immunogenicity,Medicine,Computational immunology, ...[+2]	Avg patent value: 4.52 M
17	Xalud Therapeutics, Inc.	New York, United States	Amyotrophic lateral sclerosis,Neuroscience,Health care, ...[+2]	Avg patent value: 4.36 M
18	DowElanco Ltd.	United States	Chemical engineering,Agriculture,Pest control	Avg patent value: 4.34 M
19	Regeneron Pharmaceuticals, Inc.	New York, United States	Monoclonal antibody,Clinical trial,Cholesterol, ...[+2]	Avg patent value: 4.09 M
20	Virginia Tech Intellectual Properties, Inc.	Virginia, United States	Software,Medical imaging,Digital library, ...[+2]	Avg patent value: 4.06 M
21	BASF Plant Science LLC	New Jersey, United States	Starch,Fertilizer,Plant science	Avg patent value: 3.55 M
22	Aeras Global TB Vaccine Foundation	United States	Tuberculosis vaccines,Toxoid,DNA vaccination, ...[+2]	Avg patent value: 3.32 M
23	Genentech, Inc.	California, United States	Biotechnology,Biology,Medicine, ...[+2]	Avg patent value: 3.31 M
24	Sangamo Therapeutics, Inc.	California, United States	Cell,Pharmacy and Therapeutics,Genomics, ...[+2]	Avg patent value: 3.29 M
25	Athenix Corp.	North Carolina, United States	Insect,Agriculture,Chemical engineering, ...[+2]	Avg patent value: 3.22 M
26	Pfizer Products, Inc.	Connecticut, United States		Avg patent value: 3.09 M
27	Bayer HealthCare Pharmaceuticals, Inc.	New Jersey, United States	Medicine,Cardiovascular agent,Clinical trial, ...[+2]	Avg patent value: 2.97 M
28	Viromed, Inc.	Minnesota, United States	Medical laboratory,Health care	Avg patent value: 2.92 M
29	MedImmune Vaccines, Inc.	United States	Virus,Physical fitness,Health care, ...[+1]	Avg patent value: 2.91 M
30	Wyeth LLC	New Jersey, United States		Avg patent value: 2.75 M
31	Clarient, Inc.	California, United States	Health care,Companion diagnostic,Standard of care, ...[+2]	Avg patent value: 2.73 M
32	Adhera Therapeutics, Inc.	North Carolina, United States	Familial adenomatous polyposis,Medicine,Robotics, ...[+2]	Avg patent value: 2.63 M
33	Genzyme Corp.	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,Multiple sclerosis, ...[+2]	Avg patent value: 2.56 M
34	TissueGen, Inc.	Texas, United States	Fiber,Drug-eluting stent,Stent, ...[+2]	Avg patent value: 2.56 M
35	Kolon TissueGene, Inc.	United States	Cell therapy,Health care,Genomics, ...[+2]	Avg patent value: 2.54 M
36	Vertex Pharmaceuticals, Inc.	Massachusetts, United States	Health care,Medicine,Cystic fibrosis, ...[+2]	Avg patent value: 2.54 M
37	Calimmune, Inc.	California, United States	Health care,Pharmacy and Therapeutics,Gene, ...[+2]	Avg patent value: 2.44 M
38	MedImmune LLC	Louisiana, United States	Medicine,Pharmacy and Therapeutics,Autoimmunity, ...[+2]	Avg patent value: 2.41 M
39	Roche Palo Alto LLC	California, United States	Medicine,Health care,Viral disease, ...[+1]	Avg patent value: 2.37 M
40	Medimmune, Inc.	United States	Botanical drug,Herb	Avg patent value: 2.36 M
41	Precision BioSciences, Inc.	North Carolina, United States	Genome editing,Medicine,Health care, ...[+2]	Avg patent value: 2.35 M
42	Inovio Pharmaceuticals, Inc.	Pennsylvania, United States	Medicine,Health care,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 2.26 M
43	Merck Sharp & Dohme Corp.	New Jersey, United States	Prescription drug,Medicine,Stroke, ...[+2]	Avg patent value: 2.01 M
44	BASF Agricultural Solutions Seed US LLC	United States	Chemical engineering	Avg patent value: 1.97 M
45	Applied Genetic Technologies Corp.	United States	Gene,Health care,Genomics, ...[+2]	Avg patent value: 1.96 M
46	DPx Holdings BV	Massachusetts, United States	Health care,Pharmaceutical manufacturing,Manufacturing capability, ...[+2]	Avg patent value: 1.91 M
47	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	Avg patent value: 1.91 M
48	VGX Pharmaceuticals LLC	Pennsylvania, United States	Medicine	Avg patent value: 1.86 M
49	R.P. Scherer Technologies LLC	Nevada, United States	Medical equipment,Drug,Medicine	Avg patent value: 1.70 M
50	CP Kelco US, Inc.	United States	Pectin,Carrageenan,Food processing, ...[+2]	Avg patent value: 1.54 M
51	Monsanto Technology LLC	Missouri, United States		Avg patent value: 1.51 M
52	Nature Technology Corp.	Nebraska, United States	Gene,DNA,Viral vector, ...[+2]	Avg patent value: 1.47 M
53	E.I. du Pont de Nemours & Co.	Delaware, United States	Agriculture,Materials science,Electronics, ...[+2]	Avg patent value: 1.43 M
54	Voyager Therapeutics, Inc.	Massachusetts, United States	Biology,Medicine,Health care, ...[+2]	Avg patent value: 1.42 M
55	Wilson Wolf Manufacturing Corp.	Minnesota, United States	Cell culture,Document management system,Mammalian cell, ...[+2]	Avg patent value: 1.31 M
56	Agrivida, Inc.	Massachusetts, United States	Agricultural biotechnology,Alternative fuels,Ethanol, ...[+2]	Avg patent value: 1.29 M
57	Alexion Pharmaceuticals, Inc.	Connecticut, United States	Health care,Biopharmaceutical,Clinical trial, ...[+2]	Avg patent value: 1.28 M
58	Juventas Therapeutics, Inc.	Ohio, United States	Biology,Medical equipment,Health care, ...[+2]	Avg patent value: 1.24 M
59	Protein Design Labs, Inc.	California, United States	E-commerce,Supply chain management,Turnkey	Avg patent value: 1.24 M
60	Danisco US, Inc.	Delaware, United States	Synthetic rubber,Bioplastic,Plasticizer, ...[+2]	Avg patent value: 1.17 M
61	Scarab Genomics LLC	Wisconsin, United States	Genomics,Medicine,Health care, ...[+2]	Avg patent value: 1.09 M
62	CytoDyn, Inc.	Washington, United States	Medicine,Pharmacy and Therapeutics,Virus, ...[+2]	Avg patent value: 1.05 M
63	PDL BioPharma, Inc.	Nevada, United States	Patent portfolio,Health care,Drug discovery, ...[+2]	Avg patent value: 1.00 M
64	Progenics Pharmaceuticals, Inc.	New York, United States	Medicine,Biopharmaceutical,Methylnaltrexone Bromide, ...[+2]	Avg patent value: 1.00 M
65	AbbVie Biotherapeutics, Inc.	Illinois, United States	Oncology drugs,Medicine,Oncology, ...[+2]	Avg patent value: 990,000
66	Colgate-Palmolive Co.	New York, United States	Toothpaste,Dental floss,Fast-moving consumer goods, ...[+2]	Avg patent value: 920,000
67	Merial SAS	Georgia, United States	Medicine,Health care,DNA vaccination, ...[+2]	Avg patent value: 810,000
68	J.R. Simplot Co.	Idaho, United States	Food industry,Agribusiness,Crop, ...[+2]	Avg patent value: 750,000
69	Vaccinex, Inc.	New York, United States	Antibody,Medicine,Health care, ...[+2]	Avg patent value: 740,000
70	OncoSec Medical, Inc.	California, United States	Biology,Health care,Electroporation, ...[+2]	Avg patent value: 661,597
71	Boehringer Ingelheim Animal Health USA, Inc.	United States	Medicine,Beta cell,Classical swine fever, ...[+2]	Avg patent value: 650,000
72	Firmenich SA	Minnesota, United States	Preservative,Seasoning,Odor, ...[+2]	Avg patent value: 625,000
73	Agilent Technologies, Inc.	California, United States	Genomics,Computer hardware,Semiconductor, ...[+2]	Avg patent value: 603,600
74	Nanoscope Technologies LLC	Texas, United States	Retinitis pigmentosa,Therapeutic Devices,Biomedical technology, ...[+2]	Avg patent value: 600,000
75	Protein Sciences Corp.	Connecticut, United States	Protein Sciences,Biology,Medicine, ...[+2]	Avg patent value: 510,000
76	Pioneer Hi-Bred International, Inc.	Iowa, United States		Avg patent value: 444,814
77	Regents of the University of California	California, United States	Working capital,Pathology,Companion diagnostic, ...[+2]	Avg patent value: 439,112
78	VGXI, Inc.	Texas, United States	Plasmid,Medicine,DNA vaccination, ...[+2]	Avg patent value: 426,750
79	Sapphire Energy, Inc.	California, United States	Biofuel,Biodiesel,Sapphire, ...[+2]	Avg patent value: 400,000
80	Precigen, Inc.	United States	Cell therapy,Biology,Health care, ...[+2]	Avg patent value: 382,000
81	Science & Technology Corp.	Virginia, United States	Space Science,Aerospace engineering,Systems engineering, ...[+1]	Avg patent value: 381,666
82	National Technology & Engineering Solutions of Sandia LLC	New Mexico, United States		Avg patent value: 353,333
83	Advanced BioScience Laboratories, Inc.	United States	Biologic Products,Health care,Contract Manufacturing, ...[+2]	Avg patent value: 350,000
84	NewVa Capital Partners LP	United States	Asset management	Avg patent value: 340,000
85	Bio-Rad Laboratories, Inc.	California, United States	Medicine,Proteomics,Genomics, ...[+2]	Avg patent value: 320,000
86	Salspera LLC	United States		Avg patent value: 320,000
87	Benson Hill, Inc.	Missouri, United States	Agriculture,Cloud computing,Crop, ...[+2]	Avg patent value: 310,000
88	ADViSYS, Inc.	California, United States	Software	Avg patent value: 297,777
89	STARTUP Intact Genomics, Inc.	Illinois, United States	Medical equipment,Clinical trial,Software, ...[+2]	Avg patent value: 280,000
90	STARTUP Verdia, Inc.	Texas, United States	Molecular breeding,Agriculture,Polymer, ...[+1]	Avg patent value: 240,000
91	PhyNexus, Inc.	California, United States	Health care,Plasmid,Desalting and buffer exchange, ...[+2]	Avg patent value: 230,888
92	Novartis Vaccines & Diagnostics, Inc.	New Jersey, United States	Health care,Medicine	Avg patent value: 220,000
93	Zymo Research Corp.	California, United States	Epigenetics,Microbiome,RNA, ...[+2]	Avg patent value: 190,000
94	Intertrust Technologies Corp.	California, United States	Digital rights management,Software,Enterprise software, ...[+2]	Avg patent value: 160,000
95	Abbott Cardiovascular Systems, Inc.	California, United States	Medical product,Medical equipment,Health care, ...[+2]	Avg patent value: 145,000
96	Archer-Daniels-Midland Co.	Illinois, United States	Starch,Industrial engineering,Animal feed, ...[+2]	Avg patent value: 140,000
97	Gen-Probe, Inc.	California, United States	Assay,Medicine,Streptococcus, ...[+2]	Avg patent value: 140,000
98	Sigma-Aldrich, Inc.	Missouri, United States	Biotechnology,Biology,Chemical engineering, ...[+2]	Avg patent value: 140,000
99	Signosis, Inc.	California, United States	Biomarker discovery,Medical equipment,Health care, ...[+2]	Avg patent value: 140,000
100	Schering Corp.	New Jersey, United States	Hepatitis,Medicine,Allergy	Avg patent value: 140,000