Top 100 Key Players companies in Proline by Most Patent Filings in the world in 2021 – Discovery

Free Trial

The Proline top 100 is Discovery PatSnap’ annual ranking of the top 100 Most Patent Filings Proline Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2021, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated NH₂⁺ form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO⁻ form under biological conditions), and a side chain pyrrolidine, classifying it as a nonpolar (at physiological pH), aliphatic amino acid. It is non-essential in humans, meaning the body can synthesize it from the non-essential amino acid L-glutamate. It is encoded by all the codons starting CC (CCU, CCC, CCA, and CCG).

1	Ajinomoto Co., Inc.	Tokyo, Japan	Seasoning,Amino acid,Food processing, ...[+2]	Patent: 279
2	Koninklijke DSM NV	Netherlands	Animal nutrition,Health care,Biology, ...[+2]	Patent: 179
3	F. Hoffmann-La Roche Ltd.	Switzerland	Medicine,Health care,Drug, ...[+2]	Patent: 147
4	Kyowa Hakko Kogyo Co., Ltd.	Tokyo, Japan	Fertilizer,Agrochemical,Raw material, ...[+2]	Patent: 127
5	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	Patent: 93
6	Hoechst AG	Hessen, Germany	Chemical engineering,Botanical drug,Herb, ...[+2]	Patent: 77
7	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	Patent: 63
8	Enanta Pharmaceuticals, Inc.	Massachusetts, United States	Medicine,Health care,Protease, ...[+2]	Patent: 61
9	Kaneka Corp.	Tokyo, Japan	Synthetic rubber,Chemical engineering,Polyvinyl chloride, ...[+2]	Patent: 56
10	Mitsubishi Tanabe Pharma Corp.	Osaka, Japan	Medicine,Health care,Toxoid, ...[+2]	Patent: 56
11	Degussa AG	Hessen, Germany	Precious metal,Chemical engineering,Nutrition, ...[+2]	Patent: 54
12	FIBREX Medical, Inc.	Wien, Austria	Health care	Patent: 53
13	Meiji Co., Ltd.	Tokyo, Japan	Food industry,Snack foods,Hard candy, ...[+2]	Patent: 52
14	Helix BioMedix, Inc.	Washington, United States	Peptide,Medical equipment,Medicine, ...[+2]	Patent: 41
15	XL-protein GmbH	Bayern, Germany	Medicine,Biopharmaceutical,Drug development, ...[+2]	Patent: 41
16	Suntory Beverage & Food Ltd.	Tokyo, Japan	Mineral water,Ethanol,Food industry, ...[+2]	Patent: 40
17	American Can Co.	United States	Tin can,Packaging engineering,Microservices, ...[+1]	Patent: 40
18	Sundory Co. Ltd.	Japan		Patent: 40
19	Glaxo Group Ltd.	Hounslow, United Kingdom	Food products,Medicine,Health care	Patent: 39
20	Amedeo Nappi SpA	NAPLES, Italy	Wax	Patent: 39
21	Riken Corp.	Saitama, Japan	Social network,Tappet,Piston ring, ...[+2]	Patent: 36
22	Kao Corp.	Tokyo, Japan	Cosmetics,Health care,Hair conditioner, ...[+2]	Patent: 35
23	Smithkline Beckman Corp	Pennsylvania, United States	Biotechnology,Medicine	Patent: 34
24	Novartis AG	Basel-Stadt, Switzerland	Dosage form,Health care,Medicine, ...[+2]	Patent: 33
25	Otsuka Pharmaceutical Factory, Inc.	Tokushima, Japan	Parenteral nutrition,Human nutrition,Drug, ...[+2]	Patent: 33
26	Los Alamos National Security LLC	New Mexico, United States	National security	Patent: 33
27	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	Patent: 32
28	Amgen, Inc.	California, United States	Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER, ...[+2]	Patent: 32
29	Sandoz AG	Switzerland	Botanical drug,Herb	Patent: 32
30	Bristol Myers Co.	New York, United States	Botanical drug,Herb	Patent: 32
31	Akzo Nobel NV	Noord-Holland, Netherlands	Coating,Powder coating,Chemical engineering, ...[+2]	Patent: 31
32	Sumitomo Chemical Co., Ltd.	Tokyo, Japan	Petrochemical,Agriculture,Pesticide, ...[+2]	Patent: 31
33	Daiichi Sankyo Co., Ltd.	New Jersey, Japan	Clinical trial,Cardiovascular agent,Drug, ...[+2]	Patent: 31
34	Sumitomo Pharma Co., Ltd.	Osaka, Japan	Medicine,Health care,Clinical trial, ...[+2]	Patent: 31
35	Sumitomo Pharmaceuticals Co., Ltd.	Osaka, Japan	Botanical drug,Herb	Patent: 31
36	L'Oréal SA	Île-de-France, France	Cosmetics,Urban decay,Hair conditioner, ...[+2]	Patent: 30
37	Lonza Ltd.	Switzerland	Pharmacy	Patent: 30
38	Eli Lilly & Co.	Indiana, United States	Medicine,Health care,Humalog Mix, ...[+2]	Patent: 29
39	Astellas Pharma, Inc.	Tokyo, Japan	Health care,Clinical trial,Diabetic complication, ...[+2]	Patent: 29
40	Imperial Chemical Industries Ltd.	United Kingdom	Coating,Industrial engineering,Biocide, ...[+2]	Patent: 29
41	Pentraxin Therapeutics Ltd.	United Kingdom	Drug discovery,Health care,Pharmacy and Therapeutics, ...[+1]	Patent: 29
42	Ciba Specialty Chemicals Holding, Inc.	Basel-Stadt, Switzerland	Chelate agent,Health care,Chemical engineering, ...[+2]	Patent: 28
43	Bayer HealthCare Pharmaceuticals, Inc.	New Jersey, United States	Medicine,Cardiovascular agent,Clinical trial, ...[+2]	Patent: 28
44	Société D'Etudes Dermatologiques SASU	Île-de-France, France	Colourant,Active ingredient,Cosmetics, ...[+2]	Patent: 28
45	Sankyo Co., Ltd.	Tokyo, Japan	Ball bearing,Manufacturing engineering,Glatiramer acetate, ...[+2]	Patent: 27
46	Vantia Ltd.	Hampshire, United Kingdom	Small molecule,Medicine,Pharmacy and Therapeutics, ...[+2]	Patent: 27
47	Pfizer Products, Inc.	Connecticut, United States		Patent: 27
48	Shiseido Co., Ltd.	Tokyo, Japan	Cosmetics,Elixir,Personal Care Product, ...[+2]	Patent: 26
49	DuPont Nutrition Biosciences ApS	Hovedstaden, Denmark	Food science,Medicine,Health care, ...[+2]	Patent: 26
50	Société des Produits Nestlé SA	Vaud, Switzerland	Food industry	Patent: 26
51	UAB Research Foundation	Alabama, United States	Biotechnology,Agriculture,Fishery, ...[+2]	Patent: 26
52	BASF SE	Rheinland-Pfalz, Germany	Agriculture,Petrochemical,Chemical engineering, ...[+2]	Patent: 25
53	Janssen Pharmaceutica NV	Antwerpen, Belgium	Product design,Neuroscience,Health care, ...[+2]	Patent: 25
54	Richter Gedeon Vegyészeti Gyár Rt. mellett muködo Munkahelyi	Hungary		Patent: 25
55	CSL Behring GmbH	Hessen, Germany	Medicine	Patent: 25
56	Bayer AG	Nordrhein-Westfalen, Germany	Health care,Biology,Chemical engineering, ...[+2]	Patent: 24
57	AstraZeneca Plc	Cambridgeshire, United Kingdom	Medicine,Health care,Side effect, ...[+2]	Patent: 24
58	AstraZeneca UK Ltd.	Cambridgeshire, United Kingdom	Gastrointestinal infections,Medicine,Simvastatin, ...[+2]	Patent: 24
59	Kotobuki Pharmaceutical Co. Ltd.	Shizuoka, Japan	Medicine,Health care,Pharmacy and Therapeutics, ...[+2]	Patent: 24
60	Evonik Degussa Japan Co., Ltd.	Tokyo, Japan		Patent: 24
61	Schering Corp.	New Jersey, United States	Hepatitis,Medicine,Allergy	Patent: 24
62	Bayer Oy	Finland		Patent: 24
63	Merck Patent GmbH	Hessen, Germany		Patent: 23
64	Japan Tobacco, Inc.	Tokyo, Japan	Nicotiana tabacum,Cigarillo,Food sector, ...[+2]	Patent: 22
65	Idemitsu Kosan Co., Ltd.	Tokyo, Japan	Petrochemical,Lubricant,Petroleum, ...[+2]	Patent: 22
66	Unilever NV	Zuid-Holland, Netherlands	COLA (software architecture),Soft drink,Deodorant, ...[+2]	Patent: 22
67	Ono Pharmaceutical Co., Ltd.	Osaka, Japan	Diagnostic Reagent,Medicine,Health care, ...[+2]	Patent: 22
68	Grünenthal GmbH	Nordrhein-Westfalen, Germany	Medicine,Health care,Clinical trial, ...[+2]	Patent: 22
69	The a2 Milk Co. Ltd.	Auckland, New Zealand	Infant formula,Food industry,Medicine, ...[+2]	Patent: 21
70	Amano Enzyme, Inc.	Nagano, Japan	Enzyme,Drug,Chemical engineering, ...[+2]	Patent: 21
71	Menarini International Operations Luxembourg SA	Luxembourg, Luxembourg	Drug,Medicine	Patent: 21
72	Zeneca Garden Care	United Kingdom	Agrochemical,Pharmacy,Medicine, ...[+1]	Patent: 21
73	Toyobo Co., Ltd.	Osaka, Japan	Chemical engineering,Synthetic rubber,Membrane, ...[+2]	Patent: 20
74	Kyowa Kirin Co., Ltd.	Tokyo, Japan	Health care,Drug,Medicine, ...[+2]	Patent: 20
75	Chugai Pharmaceutical Co., Ltd.	Tokyo, Japan	Drug,Clinical trial,Health care, ...[+2]	Patent: 20
76	Seikagaku Corp.	Tokyo, Japan	Viscosupplementation,Health care,SURGICAL AIDS, ...[+2]	Patent: 20
77	Oxford University Innovation Ltd.	Oxfordshire, United Kingdom	Technology transfer,Angel investor,Ecosystem, ...[+2]	Patent: 20
78	Behringwerke AG	Hessen, Germany	Industrial park,Health care,Medicine, ...[+1]	Patent: 20
79	AMP-Therapeutics GmbH	Sachsen, Germany	Antibiotics,Medicine,Biomedical engineering, ...[+2]	Patent: 20
80	Takeda Pharmaceutical Co., Ltd.	Osaka, Japan	Medicine,Health care,Clinical trial, ...[+2]	Patent: 19
81	Ciba-Geigy AG	Switzerland	Botanical drug,Herb	Patent: 19
82	Takeda Chemical Industries Ltd.	Japan	Pharmaceutical drug,Botanical drug,Herb	Patent: 19
83	Virometix AG	Zürich, Switzerland	Medicine,Health care,Cancer vaccine, ...[+2]	Patent: 19
84	Eolas Therapeutics, Inc.	California, United States	Addiction,Pharmacy and Therapeutics,Nicotine, ...[+2]	Patent: 19
85	Nestlé SA	Vaud, Switzerland	Ice cream,Nutrition,Cosmetics, ...[+2]	Patent: 18
86	CJ CheilJedang Corp.	South Korea	Sugar,Food processing,Food industry, ...[+2]	Patent: 18
87	Fuji Oil Holdings, Inc.	Osaka, Japan	Soy protein,Food processing,Textured vegetable protein, ...[+2]	Patent: 18
88	bioMérieux SA	Rhône-Alpes, France	Diagnostic system,Medicine,Coronavirus, ...[+2]	Patent: 18
89	Taisho Pharmaceutical Co., Ltd.	Tokyo, Japan	Medicine,Self-medication,Drug, ...[+2]	Patent: 18
90	Purdue Pharma LP	Connecticut, United States	Opioid,Medicine,Opioid epidemic, ...[+2]	Patent: 18
91	Purdue Pharma, Inc.	Connecticut, United States	Health care,Healthcare system,Educational program, ...[+1]	Patent: 18
92	Fuji Oil Co. Ltd. (Osaka)	Osaka, Japan	Agriculture,Fertilizer,Animal fat, ...[+2]	Patent: 18
93	Nestec SA	Vaud, Switzerland	Enzyme,Nutrition,Food industry, ...[+1]	Patent: 18
94	bioMérieux, Inc.	North Carolina, United States	Medicine,Nucleic acid test,Blood Screening, ...[+2]	Patent: 18
95	CJ Corp.	South Korea	Biotechnology,Pharmaceutics,Shopping mall, ...[+2]	Patent: 17
96	Reata Pharmaceuticals, Inc.	Texas, United States	Inflammation,Medicine,Biopharmaceutical, ...[+2]	Patent: 17
97	Neuren Pharmaceuticals Ltd.	Victoria, Australia	Pharmacy and Therapeutics,Neurodegeneration,Medicine, ...[+2]	Patent: 17
98	Boehringer Ingelheim Animal Health USA, Inc.	United States	Medicine,Beta cell,Classical swine fever, ...[+2]	Patent: 17
99	STARTUP Nuritas Ltd.	Dublin, Ireland	Artificial intelligence,Data mining,Peptide, ...[+2]	Patent: 17
100	BONAC Corp.	Fukuoka, Japan	Nucleic acid,Medicine,Chemical engineering, ...[+2]	Patent: 17