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Top 100 Startups & Unicorns companies in Microorganism
by Highest Patent Value in the world in 2021

The Microorganism top 100 is Discovery PatSnap’ annual ranking of the top 100 Highest Patent Value Microorganism Startups & Unicorns in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2021, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
A microorganism, or microbe, is a microscopic organism, which may exist in its single-celled form or in a colony of cells. The possible existence of unseen microbial life was suspected from ancient times, such as in Jain scriptures from 6th century BC India and the 1st century BC book On Agriculture by Marcus Terentius Varro. Microbiology, the scientific study of microorganisms, began with their observation under the microscope in the 1670s by Antonie van Leeuwenhoek. In the 1850s, Louis Pasteur found that microorganisms caused food spoilage, debunking the theory of spontaneous generation. In the 1880s, Robert Koch discovered that microorganisms caused the diseases tuberculosis, cholera and anthrax.

Key Players

Fast-growings

Startups & Unicorns

New Entrants

Ranking Year:

2022

2021

2020

2019

2018

Region:

Global

China

Japan

United States

Denmark

United Kingdom

Germany

Canada

Spain

Israel

Finland

France

South Korea

Netherlands

Switzerland

Ranking:

Most Patent Filings

Highest Patent Value

Most Market Reports

Most News Heat

#
Company Name
Region
Tech Topics
Total
1
Mycovia Pharmaceuticals, Inc.
North Carolina, United States
Recurrent vulvovaginal candidiasis,Drug,Biomedicine,
...[+2]
Avg patent value: 8.54 M
2
Cysbio ApS
Hovedstaden, Denmark
Cell factory,Metabolic engineering,Synthetic biology,
...[+1]
Avg patent value: 4.47 M
3
AntibioTx ApS
Hovedstaden, Denmark
Antibiotics,Biology,Medicine,
...[+2]
Avg patent value: 4.12 M
4
5ensesinfood SA
Porto, Portugal
Food industry,Food processing,Functional food
Avg patent value: 3.88 M
5
Impossible Foods, Inc.
California, United States
Fish products,Mycoprotein,Nutrition,
...[+2]
Avg patent value: 3.72 M
6
AgBiome LLC
North Carolina, United States
Agriculture,Microbiome,Agricultural biotechnology,
...[+2]
Avg patent value: 3.25 M
7
SSI Diagnostica A/S
Hovedstaden, Denmark
In vitro,Medicine,Blood product,
...[+2]
Avg patent value: 2.81 M
8
Prokarium Ltd.
United Kingdom
Infection drug,Microbial genetics,Immunogenicity,
...[+2]
Avg patent value: 2.76 M
9
Azotic Technologies Ltd.
Lancashire, United Kingdom
Nitrogen,Farming industry,Gluconacetobacter
Avg patent value: 2.64 M
10
Inbiose NV
Oost-Vlaanderen, Belgium
Oligosaccharide,Pharmacy,Carbohydrate,
...[+2]
Avg patent value: 2.61 M
11
Nuvinair LLC
Texas, United States
Automotive engineering
Avg patent value: 2.48 M
12
Atriva Therapeutics GmbH
Baden-Württemberg, Germany
Antiviral therapy,Pharmacy and Therapeutics,Biopharmaceutical,
...[+1]
Avg patent value: 2.31 M
13
Renaissance BioScience Corp.
British Columbia, Canada
Yeast,Food industry,Brewers Yeast,
...[+2]
Avg patent value: 2.24 M
14
Visolis, Inc.
California, United States
Environmental engineering,Renewable energy,Chemical synthesis,
...[+2]
Avg patent value: 2.10 M
15
Pneumagen Ltd.
Fife, United Kingdom
Coronavirus disease 2019 (COVID-19),Health care,Wellness Programs,
...[+2]
Avg patent value: 2.09 M
16
MARA Renewables Corp.
Nova Scotia, Canada
Renewable energy,Biotechnology,OMEGA-3 POLYUNSATURATED FATTY ACIDS,
...[+2]
Avg patent value: 2.00 M
17
TenNor Therapeutics Suzhou Ltd.
New Jersey, China
Infection drug,Medicine,Health care,
...[+2]
Avg patent value: 1.73 M
18
5D Health Protection Group Ltd.
CITY OF LIVERPOOL, United Kingdom
Contract research organization
Avg patent value: 1.72 M
19
Aquilón Cyl SL
Castilla y León, Spain
Spherium,Biology,Intellectual property,
...[+2]
Avg patent value: 1.69 M
20
BioConsortia, Inc.
California, United States
Plant breeding,Agriculture,Farming industry,
...[+2]
Avg patent value: 1.67 M
21
Omnix Medical Ltd.
Jerusalem, Israel
Antibiotic Agents,Health care,Odds,
...[+1]
Avg patent value: 1.62 M
22
Senseup Biotechnology
Nordrhein-Westfalen, Germany
Metabolomics,Chemical engineering,Genomics
Avg patent value: 1.57 M
23
Colorifix Ltd.
United Kingdom
Dyeing,Synthetic biology,Textile,
...[+2]
Avg patent value: 1.49 M
24
3Bar Biologics, Inc.
Ohio, United States
Agriculture,Farming industry,Crop,
...[+1]
Avg patent value: 1.48 M
25
EpiEndo Pharmaceuticals ehf
Iceland
Health care,Virtual organization,Airway disease,
...[+2]
Avg patent value: 1.48 M
26
Data Over Ego
Avg patent value: 1.44 M
27
JeNaCell GmbH
Thüringen, Germany
Cosmetics,Nanostructure,Medical equipment,
...[+2]
Avg patent value: 1.36 M
28
Synata Bio, Inc.
Illinois, United States
Power transmission,Thermoplastic,Polypropylene,
...[+1]
Avg patent value: 1.36 M
29
Verdesian Life Sciences LLC
North Carolina, United States
Seed treatment,Biology,Nutrition,
...[+2]
Avg patent value: 1.32 M
30
Pendulum Therapeutics, Inc.
California, United States
Human microbiome,Biology,Wellness Programs,
...[+2]
Avg patent value: 1.22 M
31
Biosyntia ApS
Hovedstaden, Denmark
Metabolic engineering,Synthetic biology,Medical equipment,
...[+2]
Avg patent value: 1.18 M
32
Parabel Nutrition, Inc.
United States
Agriculture,Farming industry,Fodder,
...[+2]
Avg patent value: 1.09 M
33
Sept Pty Ltd.
United States
Wellness Programs
Avg patent value: 1.08 M
34
CHAIN Antimicrobials Oy
Finland
Peptide,Antimicrobial peptides,Catheter
Avg patent value: 1.01 M
35
Lumen Bioscience, Inc.
Washington, United States
Antibody,Biology,Drug,
...[+2]
Avg patent value: 962,090
36
Wm. Wrigley Jr. Co.
Massachusetts, United States
Chewing gum,Food industry,Snack foods,
...[+2]
Avg patent value: 944,666
37
RAN Biotechnologies, Inc.
Massachusetts, United States
Biotechnology,Biosensor,Mechanical engineering,
...[+2]
Avg patent value: 930,000
38
Pivot Bio, Inc.
California, United States
Agriculture,Microbiome,Fertilizer,
...[+2]
Avg patent value: 881,695
39
Mastaplex Ltd.
Otago, New Zealand
Mastitis,Farming industry,Agriculture,
...[+1]
Avg patent value: 810,000
40
Plantio, Inc.
Tokyo, Japan
Food service,Agriculture,Internet of Things
Avg patent value: 780,000
41
INSERM Limoges
E-commerce
Avg patent value: 769,176
42
Prestodiag SAS
Île-de-France, France
Telecommunications,Surface plasmon resonance imaging,Listeria,
...[+2]
Avg patent value: 750,000
43
Provivi, Inc.
California, United States
Agriculture,Chemical engineering,Pesticide,
...[+2]
Avg patent value: 702,125
44
MIP Diagnostic Ltd.
LEICESTER, United Kingdom
Polymer,Drug
Avg patent value: 680,000
45
Mootral SA
Blaenau Gwent, United Kingdom
Mootral,Agriculture,Animal feed,
...[+2]
Avg patent value: 670,000
46
Livegrow Bio LLC
Washington, United States
Botanical drug,Herb
Avg patent value: 670,000
47
Indigo Ag, Inc.
Massachusetts, United States
Agriculture,Farming industry,Nitrogen fertilizer,
...[+2]
Avg patent value: 662,000
48
Te?Ted Oy
Western Finland, Finland
Tick-borne disease,Medical equipment,Health care
Avg patent value: 650,000
49
Drylet
Texas, United States
Agricultural wastewater treatment,Health care,Agriculture,
...[+2]
Avg patent value: 626,400
50
3I Diagnostics, Inc.
United States
Serious infection
Avg patent value: 520,000
51
Integrated Agriculture Systems, Inc.
Pennsylvania, United States
Agriculture,Portable water purification,Ecosystem,
...[+1]
Avg patent value: 500,000
52
Bened Biomedical Co., Ltd.
Taiwan Province, China
Medicine,Biomedicine,Biotechnology,
...[+2]
Avg patent value: 490,000
53
Prolific Earth Sciences Corp.
New York, United States
Software,Enterprise software
Avg patent value: 479,200
54
Vyv, Inc.
New York, United States
Food processing,New class,Cleanroom,
...[+2]
Avg patent value: 436,636
55
Ixcela, Inc.
Massachusetts, United States
Microbiome,Health care,Biopharmaceutical,
...[+2]
Avg patent value: 430,000
56
HelixBind, Inc.
Massachusetts, United States
Pathogen,Medical equipment,Health care,
...[+2]
Avg patent value: 414,615
57
Advanced Substrate Technologies A/S
Midtjylland, Denmark
Biomass,Biogas,Fiber,
...[+2]
Avg patent value: 375,000
58
White Dog Labs, Inc.
Delaware, United States
Biology,Probiotic,Organism,
...[+2]
Avg patent value: 374,250
59
Zhejiang Longterm Medical Technology Co., Ltd.
Zhejiang Sheng, China
Silicone foam
Avg patent value: 360,000
60
Novolyze SAS
United States
Food industry,Food safety,Cloud database,
...[+2]
Avg patent value: 353,100
61
Industrial Microbes, Inc.
California, United States
Chemical engineering,Natural gas,Biodegradable plastic,
...[+2]
Avg patent value: 348,472
62
OutSense Diagnostics Ltd.
Israel
Colorectal cancer,Health care,Wellness Programs,
...[+2]
Avg patent value: 340,000
63
Shoreline Biome LLC
Connecticut, United States
Microbiome,Health care,Biopharmaceutical,
...[+2]
Avg patent value: 338,555
64
Xcell Therapeutics, Inc.
South Korea
Biotechnology,Agriculture,Fishery,
...[+2]
Avg patent value: 330,000
65
Biodentify BV
Zuid-Holland, Netherlands
Petroleum industry,Big data,Seabed,
...[+1]
Avg patent value: 330,000
66
Tangen Biosciences, Inc.
Connecticut, United States
Medicine,Health care,Nucleic acid detection,
...[+2]
Avg patent value: 320,500
67
Karius, Inc.
California, United States
Biology,Genetic testing,Genomics,
...[+2]
Avg patent value: 320,000
68
Microgenetics Ltd.
Wiltshire, United Kingdom
Environmental monitoring,Software,Data integrity
Avg patent value: 280,000
69
Uute Scientific Oy
Southern Finland, Finland
Biotechnology
Avg patent value: 270,000
70
SeLux Diagnostics, Inc.
Massachusetts, United States
Amplifier,Medical equipment,Health care,
...[+2]
Avg patent value: 263,222
71
PhotoDynamic, Inc.
Nova Scotia, Canada
Medical equipment,Oral hygiene,Brace,
...[+2]
Avg patent value: 260,000
72
Primordial Genetics, Inc.
California, United States
Health care,Function generator,Titer,
...[+2]
Avg patent value: 250,000
73
Innovogene Biosciences Inc
Ontario, Canada
Biotechnology,Pathogenic bacteria
Avg patent value: 250,000
74
Better Origin
Cambridgeshire, United Kingdom
Insect,Agriculture,Renewable resource,
...[+2]
Avg patent value: 240,000
75
Trelys, Inc.
California, United States
Biotechnology,Biology
Avg patent value: 233,000
76
Curza Global LLC
Utah, United States
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 227,777
77
Quantum Interface LLC
Texas, United States
Software,Quantum,Mobile device,
...[+1]
Avg patent value: 220,000
78
Spectromics Ltd.
Manchester, United Kingdom
Diagnostic system,Antibiotics,Biology,
...[+2]
Avg patent value: 210,000
79
Alga Pangea GmbH
Tirol, Austria
Health care,Wellness Programs,Photobioreactor,
...[+2]
Avg patent value: 207,250
80
Renew Biopharma, Inc.
California, United States
Cannabinoid,Cannabis,Medicine,
...[+2]
Avg patent value: 180,000
81
Eligo Bioscience SA
Île-de-France, France
Antimicrobial,Health care,CRISPR,
...[+2]
Avg patent value: 172,241
82
CareWear
Nevada, United States
Amateur sports
Avg patent value: 171,125
83
Avails Medical, Inc.
California, United States
Health care,Medical equipment,Global health,
...[+1]
Avg patent value: 170,112
84
ProdermIQ, Inc.
California, United States
Biome
Avg patent value: 169,777
85
IsoThrive, Inc.
California, United States
Microbiome,Nutrition,Animal feed,
...[+2]
Avg patent value: 146,555
86
Native Microbials, Inc.
California, United States
Ascus,Biology,Software,
...[+2]
Avg patent value: 144,242
87
MyBiotics Pharma Ltd.
HaMerkaz, Israel
Microbiome,Wellness Programs,Health care,
...[+2]
Avg patent value: 140,000
88
Vivex Biomedical, Inc.
United States
Implant,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 130,000
89
Geltor, Inc.
California, United States
Fermentation,Materials science,Natural resource,
...[+2]
Avg patent value: 130,000
90
Creatus Biosciences, Inc.
British Columbia, Canada
Biology,Agriculture,Industrial biotechnology,
...[+2]
Avg patent value: 130,000
91
S-Biomedic NV
Wisconsin, United States
Health care,Microbiome,Dermatology,
...[+2]
Avg patent value: 125,454
92
denovoMATRIX GmbH
Sachsen, Germany
Biology,Coating,Stem cell culture,
...[+1]
Avg patent value: 124,000
93
Zymtronix Catalytic Systems, Inc.
New York, United States
Enzyme,Biology,Oxidative enzyme,
...[+2]
Avg patent value: 120,000
94
Fungialert Ltd.
United Kingdom
Health care,Agriculture,Pathogen,
...[+2]
Avg patent value: 118,000
95
Azitra, Inc.
Connecticut, United States
Fast-moving consumer goods,Medicine,Health care,
...[+2]
Avg patent value: 115,041
96
SNIPR Biome ApS
Hovedstaden, Denmark
Medicine,Health care,Biome,
...[+2]
Avg patent value: 114,357
97
Clear Labs, Inc.
California, United States
Software,Big data,Nutrition,
...[+2]
Avg patent value: 110,000
98
Zbiotics Co.
California, United States
Synthetic biology,Health care,Probiotic
Avg patent value: 110,000
99
Alphanosos SAS
Midi-Pyrénées, France
Artificial intelligence,Functional food,Hygiene,
...[+1]
Avg patent value: 93,000
100
Microbe Detectives LLC
Wisconsin, United States
Water-related Diseases,Health care,Portable water purification,
...[+2]
Avg patent value: 92,000

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