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Top 100 Startups & Unicorns companies in Microorganism
by Highest Patent Value in the United States in 2019

The Microorganism top 100 is Discovery PatSnap’ annual ranking of the top 100 Highest Patent Value Microorganism Startups & Unicorns in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2019, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
A microorganism, or microbe, is a microscopic organism, which may exist in its single-celled form or in a colony of cells. The possible existence of unseen microbial life was suspected from ancient times, such as in Jain scriptures from 6th century BC India and the 1st century BC book On Agriculture by Marcus Terentius Varro. Microbiology, the scientific study of microorganisms, began with their observation under the microscope in the 1670s by Antonie van Leeuwenhoek. In the 1850s, Louis Pasteur found that microorganisms caused food spoilage, debunking the theory of spontaneous generation. In the 1880s, Robert Koch discovered that microorganisms caused the diseases tuberculosis, cholera and anthrax.

Key Players

Fast-growings

Startups & Unicorns

New Entrants

Ranking Year:

2022

2021

2020

2019

2018

Region:

Global

China

Japan

United States

Denmark

United Kingdom

Germany

Canada

Spain

Israel

Finland

France

South Korea

Netherlands

Switzerland

Ranking:

Most Patent Filings

Highest Patent Value

Most Market Reports

Most News Heat

#
Company Name
Region
Tech Topics
Total
1
Mycovia Pharmaceuticals, Inc.
North Carolina, United States
Recurrent vulvovaginal candidiasis,Drug,Biomedicine,
...[+2]
Avg patent value: 8.54 M
2
Impossible Foods, Inc.
California, United States
Fish products,Mycoprotein,Nutrition,
...[+2]
Avg patent value: 3.72 M
3
AgBiome LLC
North Carolina, United States
Agriculture,Microbiome,Agricultural biotechnology,
...[+2]
Avg patent value: 3.25 M
4
Nuvinair LLC
Texas, United States
Automotive engineering
Avg patent value: 2.48 M
5
Visolis, Inc.
California, United States
Environmental engineering,Renewable energy,Chemical synthesis,
...[+2]
Avg patent value: 2.10 M
6
BioConsortia, Inc.
California, United States
Plant breeding,Agriculture,Farming industry,
...[+2]
Avg patent value: 1.67 M
7
3Bar Biologics, Inc.
Ohio, United States
Agriculture,Farming industry,Crop,
...[+1]
Avg patent value: 1.48 M
8
Synata Bio, Inc.
Illinois, United States
Power transmission,Thermoplastic,Polypropylene,
...[+1]
Avg patent value: 1.36 M
9
Verdesian Life Sciences LLC
North Carolina, United States
Seed treatment,Biology,Nutrition,
...[+2]
Avg patent value: 1.32 M
10
Pendulum Therapeutics, Inc.
California, United States
Human microbiome,Biology,Wellness Programs,
...[+2]
Avg patent value: 1.22 M
11
Parabel Nutrition, Inc.
United States
Agriculture,Farming industry,Fodder,
...[+2]
Avg patent value: 1.09 M
12
Sept Pty Ltd.
United States
Wellness Programs
Avg patent value: 1.08 M
13
Lumen Bioscience, Inc.
Washington, United States
Antibody,Biology,Drug,
...[+2]
Avg patent value: 962,090
14
Wm. Wrigley Jr. Co.
Massachusetts, United States
Chewing gum,Food industry,Snack foods,
...[+2]
Avg patent value: 944,666
15
RAN Biotechnologies, Inc.
Massachusetts, United States
Biotechnology,Biosensor,Mechanical engineering,
...[+2]
Avg patent value: 930,000
16
Pivot Bio, Inc.
California, United States
Agriculture,Microbiome,Fertilizer,
...[+2]
Avg patent value: 881,695
17
Provivi, Inc.
California, United States
Agriculture,Chemical engineering,Pesticide,
...[+2]
Avg patent value: 702,125
18
Livegrow Bio LLC
Washington, United States
Botanical drug,Herb
Avg patent value: 670,000
19
Indigo Ag, Inc.
Massachusetts, United States
Agriculture,Farming industry,Nitrogen fertilizer,
...[+2]
Avg patent value: 662,000
20
Drylet
Texas, United States
Agricultural wastewater treatment,Health care,Agriculture,
...[+2]
Avg patent value: 626,400
21
3I Diagnostics, Inc.
United States
Serious infection
Avg patent value: 520,000
22
Integrated Agriculture Systems, Inc.
Pennsylvania, United States
Agriculture,Portable water purification,Ecosystem,
...[+1]
Avg patent value: 500,000
23
Prolific Earth Sciences Corp.
New York, United States
Software,Enterprise software
Avg patent value: 479,200
24
Vyv, Inc.
New York, United States
Food processing,New class,Cleanroom,
...[+2]
Avg patent value: 436,636
25
Ixcela, Inc.
Massachusetts, United States
Microbiome,Health care,Biopharmaceutical,
...[+2]
Avg patent value: 430,000
26
HelixBind, Inc.
Massachusetts, United States
Pathogen,Medical equipment,Health care,
...[+2]
Avg patent value: 414,615
27
White Dog Labs, Inc.
Delaware, United States
Biology,Probiotic,Organism,
...[+2]
Avg patent value: 374,250
28
Novolyze SAS
United States
Food industry,Food safety,Cloud database,
...[+2]
Avg patent value: 353,100
29
Industrial Microbes, Inc.
California, United States
Chemical engineering,Natural gas,Biodegradable plastic,
...[+2]
Avg patent value: 348,472
30
Shoreline Biome LLC
Connecticut, United States
Microbiome,Health care,Biopharmaceutical,
...[+2]
Avg patent value: 338,555
31
Tangen Biosciences, Inc.
Connecticut, United States
Medicine,Health care,Nucleic acid detection,
...[+2]
Avg patent value: 320,500
32
Karius, Inc.
California, United States
Biology,Genetic testing,Genomics,
...[+2]
Avg patent value: 320,000
33
SeLux Diagnostics, Inc.
Massachusetts, United States
Amplifier,Medical equipment,Health care,
...[+2]
Avg patent value: 263,222
34
Primordial Genetics, Inc.
California, United States
Health care,Function generator,Titer,
...[+2]
Avg patent value: 250,000
35
Trelys, Inc.
California, United States
Biotechnology,Biology
Avg patent value: 233,000
36
Curza Global LLC
Utah, United States
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 227,777
37
Quantum Interface LLC
Texas, United States
Software,Quantum,Mobile device,
...[+1]
Avg patent value: 220,000
38
Renew Biopharma, Inc.
California, United States
Cannabinoid,Cannabis,Medicine,
...[+2]
Avg patent value: 180,000
39
CareWear
Nevada, United States
Amateur sports
Avg patent value: 171,125
40
Avails Medical, Inc.
California, United States
Health care,Medical equipment,Global health,
...[+1]
Avg patent value: 170,112
41
ProdermIQ, Inc.
California, United States
Biome
Avg patent value: 169,777
42
IsoThrive, Inc.
California, United States
Microbiome,Nutrition,Animal feed,
...[+2]
Avg patent value: 146,555
43
Native Microbials, Inc.
California, United States
Ascus,Biology,Software,
...[+2]
Avg patent value: 144,242
44
Vivex Biomedical, Inc.
United States
Implant,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 130,000
45
Geltor, Inc.
California, United States
Fermentation,Materials science,Natural resource,
...[+2]
Avg patent value: 130,000
46
S-Biomedic NV
Wisconsin, United States
Health care,Microbiome,Dermatology,
...[+2]
Avg patent value: 125,454
47
Zymtronix Catalytic Systems, Inc.
New York, United States
Enzyme,Biology,Oxidative enzyme,
...[+2]
Avg patent value: 120,000
48
Azitra, Inc.
Connecticut, United States
Fast-moving consumer goods,Medicine,Health care,
...[+2]
Avg patent value: 115,041
49
Clear Labs, Inc.
California, United States
Software,Big data,Nutrition,
...[+2]
Avg patent value: 110,000
50
Zbiotics Co.
California, United States
Synthetic biology,Health care,Probiotic
Avg patent value: 110,000
51
Microbe Detectives LLC
Wisconsin, United States
Water-related Diseases,Health care,Portable water purification,
...[+2]
Avg patent value: 92,000
52
Novome Biotechnologies, Inc.
California, United States
Pharmacy and Therapeutics,Synthetic biology,Biotechnology,
...[+2]
Avg patent value: 85,714
53
AllerPops Corp.
New Mexico, United States
Probiotic,Immune system,Medicine,
...[+1]
Avg patent value: 80,833
54
Applied Silver, Inc.
California, United States
Virus,Health care,Textile
Avg patent value: 80,000
55
Gross-Wen Technologies, Inc.
Iowa, United States
Waste management,Software,Biotechnology,
...[+2]
Avg patent value: 77,000
56
AOBiome LLC
Massachusetts, United States
Medicine,Health care,Atopic dermatitis,
...[+2]
Avg patent value: 76,260
57
Solarea Bio, Inc.
Massachusetts, United States
Microbiome,Inflammation,Health care,
...[+1]
Avg patent value: 70,250
58
Sun Genomics, Inc.
California, United States
Microbiome,Health care,Dysbiosis,
...[+2]
Avg patent value: 67,155
59
SciBac, Inc.
California, United States
Microbiome,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 66,909
60
Dalan Animal Health, Inc.
Georgia, United States
Health care
Avg patent value: 65,000
61
Mavupharma, Inc.
Washington, United States
Clinical research,Biology,Health care,
...[+2]
Avg patent value: 65,000
62
Spero Foods, Inc.
California, United States
Food processing,Food industry,Organic matter
Avg patent value: 64,000
63
Viscus Biologics LLC
Ohio, United States
Biologic Products,Medical equipment
Avg patent value: 64,000
64
MicrobeDx, Inc.
California, United States
Health care,Hospitality industry,Molecular diagnostics,
...[+2]
Avg patent value: 63,280
65
TerMir, Inc.
North Carolina, United States
Agriculture
Avg patent value: 58,000
66
Light Bio, Inc.
Wisconsin, United States
Synthetic biology,Biology,Bioluminescence,
...[+1]
Avg patent value: 58,000
67
Centennial Technologies, Inc.
Virginia, United States
Computer hardware,Electronics,Peripheral,
...[+2]
Avg patent value: 55,000
68
Cybele Microbiome, Inc.
California, United States
Non-human,Fast-moving consumer goods,Microbiome
Avg patent value: 54,000
69
General Automation Lab Technologies, Inc.
California, United States
Microbiology,Dendritic cell,Cell sorting,
...[+2]
Avg patent value: 51,750
70
KnipBio, Inc.
Massachusetts, United States
Carotenoid,Aquaculture,Nutrition,
...[+2]
Avg patent value: 51,000
71
Briotech, Inc.
Washington, United States
Immune system,Inflammation,Chemical engineering
Avg patent value: 49,000
72
Boragen, Inc.
North Carolina, United States
Biology,Agriculture,Chemical engineering,
...[+2]
Avg patent value: 46,000
73
MycoWorks, Inc.
California, United States
Sustainable design,Renewable energy,Genetic engineering,
...[+2]
Avg patent value: 45,000
74
Boost Biomes, Inc.
California, United States
Throughput,Informatics,Agriculture,
...[+1]
Avg patent value: 44,000
75
DermBiont, Inc.
Massachusetts, United States
Microbiome,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 42,975
76
Animal Microbiome Analytics, Inc.
California, United States
Microbiome,Health care,Medicine,
...[+2]
Avg patent value: 42,000
77
RevaTis SA
Texas, United States
Agriculture,Stem cell,Mesenchymal stem cell,
...[+2]
Avg patent value: 41,000
78
Biomason, Inc.
North Carolina, United States
Chemical process,Microorganism,Masonry,
...[+2]
Avg patent value: 39,400
79
BioPlx, Inc.
Colorado, United States
Microbiome,Biology,Intellectual property
Avg patent value: 37,571
80
Day Zero Diagnostics, Inc.
Massachusetts, United States
New class,Medical equipment,Health care,
...[+2]
Avg patent value: 35,363
81
MarvelBiome, Inc.
Massachusetts, United States
Biopharmaceutical,Herb,Botanical drug
Avg patent value: 35,000
82
MatriSys Bioscience, Inc.
California, United States
Biopharmaceutical,Microbiome,Health care,
...[+2]
Avg patent value: 31,000
83
Human Longevity, Inc.
California, United States
Medical equipment,Health care,Longevity,
...[+2]
Avg patent value: 30,333
84
ZVerse, Inc.
South Carolina, United States
3D printing,Software,CAD,
...[+2]
Avg patent value: 29,000
85
Siolta Therapeutics, Inc.
California, United States
Biotechnology,Microbiome,Biopharmaceutical,
...[+2]
Avg patent value: 29,000
86
The EVERY Co.
California, United States
Nutrition,Food processing,Egg protein,
...[+2]
Avg patent value: 27,000
87
Acenxion Biosystems, Inc.
Kansas, United States
Antibiotic resistance,Antimicrobial susceptibility,Antibiotics,
...[+2]
Avg patent value: 27,000
88
Trace Genomics, Inc.
California, United States
Agriculture,Genomics,Farming industry,
...[+2]
Avg patent value: 24,842
89
TechGo
New York, United States
Graphic design,Network security,Web design,
...[+1]
Avg patent value: 24,000
90
Antheia, Inc.
California, United States
Synthetic biology,Medical equipment,Medicine,
...[+2]
Avg patent value: 24,000
91
Clearleaf
Delaware, United States
Postharvest,Farming industry,Agriculture,
...[+1]
Avg patent value: 24,000
92
Dren Bio
California, United States
Biology,Health care,Cell,
...[+2]
Avg patent value: 21,225
93
Biome Makers, Inc.
California, United States
Microbiome,Biome,Winemaking,
...[+2]
Avg patent value: 21,000
94
Gusto Global, LLC
North Carolina, United States
Microbiome,Biopharmaceutical,Companion diagnostic,
...[+2]
Avg patent value: 21,000
95
Peptilogics, Inc.
Pennsylvania, United States
Antibiotics,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 19,000
96
Zymochem, Inc.
California, United States
Industrial engineering,Chemical engineering,Carbon,
...[+2]
Avg patent value: 19,000
97
Holobiome, Inc.
Massachusetts, United States
Central nervous system,Pharmacy and Therapeutics,Microbiome,
...[+2]
Avg patent value: 18,200
98
Essenlix Corp.
New Jersey, United States
Digital health,Software
Avg patent value: 18,000
99
The BioCollective
Colorado, United States
Microbiome,Biology,Nutrition,
...[+2]
Avg patent value: 18,000
100
Collidion
California, United States
Private healthcare,Health care,Apomorphine,
...[+2]
Avg patent value: 18,000

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