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Top 10 Key Players companies in Connective tissue disease
by Highest Patent Value in the United States in 2021

The Connective tissue disease top 10 is Discovery PatSnap’ annual ranking of the top 10 Highest Patent Value Connective tissue disease Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2021, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
A connective tissue disease (collagenosis) is any disease that has the connective tissues of the body as a target of pathology. Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds together, and protects organs. These tissues form a framework, or matrix, for the body, and are composed of two major structural protein molecules: collagen and elastin. There are many different types of collagen protein in each of the body's tissues. Elastin has the capability of stretching and returning to its original length—like a spring or rubber band. Elastin is the major component of ligaments (tissues that attach bone to bone) and skin. In patients with connective tissue disease, it is common for collagen and elastin to become injured by inflammation (ICT). Many connective tissue diseases feature abnormal immune system activity with inflammation in tissues as a result of an immune system that is directed against one's own body tissues (autoimmunity).
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Company Name
Region
Tech Topics
Total
1
Bioniz Therapeutics, Inc.
Medical equipment,Health care,Molecule,
...[+2]
Avg patent value: 7.83 M
2
Global Blood Therapeutics, Inc.
Pharmacy and Therapeutics,Medicine,Health care,
...[+2]
Avg patent value: 2.97 M
3
Pfizer Inc.
Health care,Clinical trial,Drug,
...[+2]
Avg patent value: 2.55 M
4
Tobira Therapeutics, Inc.
Medicine,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 1.77 M
5
Mesoblast, Inc.
Orthopedic disorders,Drug,Medicine,
...[+2]
Avg patent value: 1.43 M
6
Oncoheroes Biosciences Inc
Drug,Medicine
Avg patent value: 710,000
7
Boehringer Ingelheim Pharmaceuticals, Inc.
Central nervous system,Medicine,Drug,
...[+2]
Avg patent value: 710,000
8
Medtronic, Inc.
Medicine,Implantable cardiac pacemaker,Biomedical engineering,
...[+2]
Avg patent value: 520,000
9
Angion Biomedica Corp.
Acute kidney injury,Medicine,Health care,
...[+2]
Avg patent value: 91,000
10
Axolotl Biologix, Inc.
Biotechnology,Regenerative medicine,Health care
Avg patent value: 3,900
Page generation time: Jul 05 2025