Top 10 Key Players companies in Lysosome by Most Literature Citation in the United States in 2019 – Discovery

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The Lysosome top 10 is Discovery PatSnap’ annual ranking of the top 10 Most Literature Citation Lysosome Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2019, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

A lysosome (/ˈlaɪsəˌsoʊm/) is a membrane-bound organelle found in many animal cells. They are spherical vesicles that contain hydrolytic enzymes that can break down many kinds of biomolecules. A lysosome has a specific composition, of both its membrane proteins, and its lumenal proteins. The lumen's pH (~4.5–5.0) is optimal for the enzymes involved in hydrolysis, analogous to the activity of the stomach. Besides degradation of polymers, the lysosome is involved in various cell processes, including secretion, plasma membrane repair, cell signaling, and energy metabolism.

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1	The Brigham & Women's Hospital, Inc.	Massachusetts, United States	Health care,Mitral valve surgery,Health equity, ...[+2]	Literature citation: 4,571
2	Howard Hughes Medical Institute	United States	Science education,Medical equipment,Health care, ...[+2]	Literature citation: 3,006
3	The Center for Advanced Biotechnology & Medicine	New Jersey, United States		Literature citation: 1,486
4	Houston Methodist St. Catherine Hospital	Texas, United States	Health care,Hospitality industry,Continuing care, ...[+2]	Literature citation: 1,339
5	Genzyme Ltd	Massachusetts, United States	Medicine,Biotechnology,Donation, ...[+1]	Literature citation: 1,282
6	Beth Israel Deaconess Medical Center, Inc.	Massachusetts, United States	Medical school,Clinical research,Health care, ...[+2]	Literature citation: 1,183
7	University of Cincinnati Academic Health Center	Ohio, United States	Health care,Medicine,Biology, ...[+2]	Literature citation: 1,016
8	U.S. Department of Agriculture	District of Columbia, United States	Agriculture,Food industry,Farming industry, ...[+2]	Literature citation: 855
9	The Broad Institute, Inc.	Massachusetts, United States	Clinical trial,Biology,Genomics, ...[+2]	Literature citation: 853
10	U.S. Department of Veteran Affairs	District of Columbia, United States	Health care,National security,Health Insurance Portability and Accountability Act, ...[+2]	Literature citation: 733