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Top 10 Key Players companies in Psilocybin
by Highest Patent Value in the United States in 2021

The Psilocybin top 10 is Discovery PatSnap’ annual ranking of the top 10 Highest Patent Value Psilocybin Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2021, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
Psilocybin (/ˌsaɪləˈsaɪbɪn/ sy-lə-SY-bin) is a naturally occurring psychedelic prodrug compound produced by more than 200 species of mushrooms, collectively known as psilocybin mushrooms. The most potent are members of the genus Psilocybe, such as P. azurescens, P. semilanceata, and P. cyanescens, but psilocybin has also been isolated from about a dozen other genera. As a prodrug, psilocybin is quickly converted by the body to psilocin, which has mind-altering effects similar, in some aspects, to those of LSD, mescaline, and DMT. In general, the effects include euphoria, visual and mental hallucinations, changes in perception, a distorted sense of time, spiritual experiences, and can include possible adverse reactions such as nausea and panic attacks.
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Company Name
Region
Tech Topics
Total
1
Chemical compound,Experimental data,Health care
Avg patent value: 48,000
2
Avg patent value: 42,800
3
Cannabinoid,Pharmacy and Therapeutics,Cannabis,
...[+1]
Avg patent value: 17,000
4
Empyrean Neuroscience, Inc.
Avg patent value: 14,000
5
Severe osteoporosis,Medicine,Health care,
...[+2]
Avg patent value: 0
6
E-commerce,Social consciousness,Music,
...[+2]
Avg patent value: 0
7
Avg patent value: 0
8
Orthogonal Thinker, Inc.
Psilocybin,Emotional intelligence
Avg patent value: 0
9
Avg patent value: 0
10
Avg patent value: 0
Page generation time: Jun 21 2025