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Top 20 Fast-growings companies in Calprotectin
by Most Patent Filing In 5 Years in the world in 2021

The Calprotectin top 20 is Discovery PatSnap’ annual ranking of the top 20 Most Patent Filing In 5 Years Calprotectin Fast-growings in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2021, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
Calprotectin is a complex of the mammalian proteins S100A8 and S100A9. In the presence of calcium, calprotectin is capable of sequestering the transition metals iron, manganese and zinc via chelation. This metal sequestration affords the complex antimicrobial properties. Calprotectin is the only known antimicrobial manganese sequestration protein complex. Calprotectin comprises as much as 60% of the soluble protein content of the cytosol of a neutrophil, and it is secreted by an unknown mechanism during inflammation. Faecal calprotectin has been used to detect intestinal inflammation (colitis or enteritis) and can serve as a biomarker for inflammatory bowel diseases and Rheumatoid Arthritis. Other names for calprotectin include MRP8-MRP14, calgranulin A and B, cystic fibrosis antigen, L1, 60BB antigen, and 27E10 antigen.
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Company Name
Region
Tech Topics
Total
1
Hessen, Germany
Health care,Scientific organization,Business relations,
...[+2]
Patent: 8
2
Patent: 6
3
Basel-Landschaft, Switzerland
Familial adenomatous polyposis,Health care,Gastrointestinal agent,
...[+1]
Patent: 5
4
Rheinland-Pfalz, Germany
Patent: 5
5
Patent: 3
6
Basel-Stadt, Switzerland
Patent: 3
7
Patent: 2
8
Retail clinic,Software,Enterprise software,
...[+2]
Patent: 2
9
Institut Gustave Roussy EURL
Île-de-France, France
Patent: 1
10
CITY OF LIVERPOOL, United Kingdom
Public university,The Internet,Medicine,
...[+2]
Patent: 1
11
Patent: 1
12
Sweden
Patent: 1
13
Pinyin,Educational institution,Cancer immunotherapy,
...[+2]
Patent: 1
14
Ukraine
Ukrainian,Medicine,Internal medicine,
...[+2]
Patent: 1
15
Patent: 1
16
Hovedstaden, Denmark
Patent: 1
17
Medical laboratory,Health care
Patent: 1
18
Clinical trial,Liberal arts education,Clinical expertise,
...[+2]
Patent: 1
19
Medicine,Health care,Humalog Mix,
...[+2]
Patent: 1
20
Patent: 1
Page generation time: Dec 16 2025