Top 20 Key Players companies in Calprotectin by Most Patent Filings in the world in 2021 – Discovery

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The Calprotectin top 20 is Discovery PatSnap’ annual ranking of the top 20 Most Patent Filings Calprotectin Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2021, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

Calprotectin is a complex of the mammalian proteins S100A8 and S100A9. In the presence of calcium, calprotectin is capable of sequestering the transition metals iron, manganese and zinc via chelation. This metal sequestration affords the complex antimicrobial properties. Calprotectin is the only known antimicrobial manganese sequestration protein complex. Calprotectin comprises as much as 60% of the soluble protein content of the cytosol of a neutrophil, and it is secreted by an unknown mechanism during inflammation. Faecal calprotectin has been used to detect intestinal inflammation (colitis or enteritis) and can serve as a biomarker for inflammatory bowel diseases and Rheumatoid Arthritis. Other names for calprotectin include MRP8-MRP14, calgranulin A and B, cystic fibrosis antigen, L1, 60BB antigen, and 27E10 antigen.

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Ranking:

1	Axis-Shield AS	Norway		Patent: 18
2	Immundiagnostik AG	Hessen, Germany	Health care,Scientific organization,Business relations, ...[+2]	Patent: 10
3	Bühlmann Laboratories AG	Basel-Stadt, Switzerland	Drug discovery,Pharmacology	Patent: 8
4	F. Hoffmann-La Roche Ltd.	Switzerland	Medicine,Health care,Drug, ...[+2]	Patent: 7
5	DiaSys Diagnostic Systems GmbH	Rheinland-Pfalz, Germany	Medicine,Photometer,Point-of-care testing, ...[+2]	Patent: 5
6	Mologic Ltd.	Northamptonshire, United Kingdom	Medical equipment,Health care,Clinical trial, ...[+2]	Patent: 5
7	S.L.A. Pharma AG	Basel-Landschaft, Switzerland	Familial adenomatous polyposis,Health care,Gastrointestinal agent, ...[+1]	Patent: 5
8	Certest Biotec SL	Spain	Biotechnology,Helicobacter,In vitro, ...[+2]	Patent: 5
9	Nature's Sunshine Products, Inc.	Utah, United States	Vitamin,Medical equipment,Herb, ...[+2]	Patent: 3
10	Roche Diagnostics Corp.	Indiana, United States	Medicine,Urinalysis,Immunoassay, ...[+2]	Patent: 2
11	ProciseDx LLC	California, United States	Retail clinic,Software,Enterprise software, ...[+2]	Patent: 2
12	Eli Lilly & Co.	Indiana, United States	Medicine,Health care,Humalog Mix, ...[+2]	Patent: 1
13	Shiseido Co., Ltd.	Tokyo, Japan	Cosmetics,Elixir,Personal Care Product, ...[+2]	Patent: 1
14	Lion Corp.	Tokyo, Japan	Toothpaste,Fast-moving consumer goods,Laundry, ...[+2]	Patent: 1
15	Shofu, Inc.	Kyoto, Japan	Medical equipment,Cosmetics,Macropinocytic cup, ...[+2]	Patent: 1
16	Probi AB	Sweden	Probiotic,Functional food,Food industry, ...[+2]	Patent: 1
17	Academisch Ziekenhuis Maastricht	Netherlands	Medical research,Health care,Hospitality industry	Patent: 1
18	Nordic Bioscience A/S	Hovedstaden, Denmark	Drug development,Health care,Precision medicine, ...[+2]	Patent: 1
19	ScheBo Biotech AG	Hessen, Germany	Biochemist,Veterinary hematology,Creative problem, ...[+2]	Patent: 1
20	Zhuhai Encode Medical Engineering Co., Ltd.	Guangdong Sheng, China	Medical laboratory,Health care	Patent: 1