Top 20 Key Players companies in Lysosome by Most Literature Citation in the United States in 2018 – Discovery

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The Lysosome top 20 is Discovery PatSnap’ annual ranking of the top 20 Most Literature Citation Lysosome Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2018, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

A lysosome (/ˈlaɪsəˌsoʊm/) is a membrane-bound organelle found in many animal cells. They are spherical vesicles that contain hydrolytic enzymes that can break down many kinds of biomolecules. A lysosome has a specific composition, of both its membrane proteins, and its lumenal proteins. The lumen's pH (~4.5–5.0) is optimal for the enzymes involved in hydrolysis, analogous to the activity of the stomach. Besides degradation of polymers, the lysosome is involved in various cell processes, including secretion, plasma membrane repair, cell signaling, and energy metabolism.

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1	The Brigham & Women's Hospital, Inc.	Massachusetts, United States	Health care,Mitral valve surgery,Health equity, ...[+2]	Literature citation: 4,505
2	Howard Hughes Medical Institute	United States	Science education,Medical equipment,Health care, ...[+2]	Literature citation: 2,937
3	McLean Hospital, Inc.	Massachusetts, United States	Mental illness,Mental health,Substance abuse, ...[+2]	Literature citation: 2,006
4	The Center for Advanced Biotechnology & Medicine	New Jersey, United States		Literature citation: 1,469
5	Houston Methodist St. Catherine Hospital	Texas, United States	Health care,Hospitality industry,Continuing care, ...[+2]	Literature citation: 1,328
6	Genzyme Ltd	Massachusetts, United States	Medicine,Biotechnology,Donation, ...[+1]	Literature citation: 1,282
7	Beth Israel Deaconess Medical Center, Inc.	Massachusetts, United States	Medical school,Clinical research,Health care, ...[+2]	Literature citation: 1,122
8	University of Cincinnati Academic Health Center	Ohio, United States	Health care,Medicine,Biology, ...[+2]	Literature citation: 995
9	Schering-Plough Pharmaceuticals	New Jersey, United States	Health care	Literature citation: 956
10	U.S. Department of Agriculture	District of Columbia, United States	Agriculture,Food industry,Farming industry, ...[+2]	Literature citation: 855
11	The Broad Institute, Inc.	Massachusetts, United States	Clinical trial,Biology,Genomics, ...[+2]	Literature citation: 714
12	U.S. Department of Veteran Affairs	District of Columbia, United States	Health care,National security,Health Insurance Portability and Accountability Act, ...[+2]	Literature citation: 660
13	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	Literature citation: 575
14	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	Literature citation: 411
15	The National Research Council	District of Columbia, United States	Public opinion,Health care,Chemistry, ...[+2]	Literature citation: 333
16	Van Andel Institute	Michigan, United States	Germline,Xenotransplantation,Cytogenetics, ...[+2]	Literature citation: 331
17	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	Literature citation: 307
18	Memorial Hospital & Health System	Indiana, United States	Health care,Hospitality industry,Childbirth, ...[+2]	Literature citation: 190
19	UCLA Medical Center	California, United States	Primary care,Dendritic cell,Cell sorting, ...[+2]	Literature citation: 105
20	Cleveland Clinic	OH, US	Health care,Face transplant,Coronary artery bypass surgery, ...[+2]	Literature citation: 95