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Top 20 New Entrants companies in Calprotectin
by Most Patent Filing In 5 Years in the world in 2021

The Calprotectin top 20 is Discovery PatSnap’ annual ranking of the top 20 Most Patent Filing In 5 Years Calprotectin New Entrants in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2021, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
Calprotectin is a complex of the mammalian proteins S100A8 and S100A9. In the presence of calcium, calprotectin is capable of sequestering the transition metals iron, manganese and zinc via chelation. This metal sequestration affords the complex antimicrobial properties. Calprotectin is the only known antimicrobial manganese sequestration protein complex. Calprotectin comprises as much as 60% of the soluble protein content of the cytosol of a neutrophil, and it is secreted by an unknown mechanism during inflammation. Faecal calprotectin has been used to detect intestinal inflammation (colitis or enteritis) and can serve as a biomarker for inflammatory bowel diseases and Rheumatoid Arthritis. Other names for calprotectin include MRP8-MRP14, calgranulin A and B, cystic fibrosis antigen, L1, 60BB antigen, and 27E10 antigen.
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Company Name
Region
Tech Topics
Total
1
Patent: 6
2
Rheinland-Pfalz, Germany
Patent: 5
3
Basel-Landschaft, Switzerland
Familial adenomatous polyposis,Health care,Gastrointestinal agent,
...[+1]
Patent: 5
4
Patent: 3
5
Patent: 2
6
Retail clinic,Software,Enterprise software,
...[+2]
Patent: 2
7
Institut Gustave Roussy EURL
Île-de-France, France
Patent: 1
8
Medical laboratory,Health care
Patent: 1
9
CITY OF LIVERPOOL, United Kingdom
Public university,The Internet,Medicine,
...[+2]
Patent: 1
10
Clinical trial,Liberal arts education,Clinical expertise,
...[+2]
Patent: 1
11
Patent: 1
12
Sweden
Patent: 1
13
Pinyin,Educational institution,Cancer immunotherapy,
...[+2]
Patent: 1
14
Medicine,Health care,Humalog Mix,
...[+2]
Patent: 1
15
Patent: 1
16
Ukraine
Ukrainian,Medicine,Internal medicine,
...[+2]
Patent: 1
17
Patent: 1
18
Tokyo, Japan
Toothpaste,Fast-moving consumer goods,Laundry,
...[+2]
Patent: 1
19
Patent: 1
20
Hovedstaden, Denmark
Patent: 1
Page generation time: Dec 18 2025