Top 50 Fast-growings companies in Lysosome by Most Patent Filing In 5 Years in the United States in 2018 – Discovery

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The Lysosome top 50 is Discovery PatSnap’ annual ranking of the top 50 Most Patent Filing In 5 Years Lysosome Fast-growings in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2018, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

A lysosome (/ˈlaɪsəˌsoʊm/) is a membrane-bound organelle found in many animal cells. They are spherical vesicles that contain hydrolytic enzymes that can break down many kinds of biomolecules. A lysosome has a specific composition, of both its membrane proteins, and its lumenal proteins. The lumen's pH (~4.5–5.0) is optimal for the enzymes involved in hydrolysis, analogous to the activity of the stomach. Besides degradation of polymers, the lysosome is involved in various cell processes, including secretion, plasma membrane repair, cell signaling, and energy metabolism.

1	Amicus Therapeutics, Inc.	New Jersey, United States	Pharmacological chaperone,Medicine,Health care, ...[+2]	Patent: 45
2	Shire Human Genetic Therapies, Inc.	Massachusetts, United States	Medicine	Patent: 44
3	BioMarin Pharmaceutical, Inc.	California, United States	Software development,Biopharmaceutical,Clinical trial, ...[+2]	Patent: 33
4	Regeneron Pharmaceuticals, Inc.	New York, United States	Monoclonal antibody,Clinical trial,Cholesterol, ...[+2]	Patent: 29
5	STARTUP Prevail Therapeutics, Inc.	New York, United States	Gene,Health care,Pharmacy and Therapeutics, ...[+2]	Patent: 24
6	Genzyme Corp.	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,Multiple sclerosis, ...[+2]	Patent: 20
7	Sarepta Therapeutics, Inc.	Massachusetts, United States	Pharmacy and Therapeutics,Health care,Approved drug, ...[+2]	Patent: 16
8	The University of California, San Francisco	California, United States	Nursing,Health care,Association (object-oriented programming), ...[+2]	Patent: 14
9	University of Washington	Washington, United States	Machine learning,Lecture hall,Energy storage, ...[+2]	Patent: 14
10	Regents of the University of California	California, United States	Working capital,Pathology,Companion diagnostic, ...[+2]	Patent: 14
11	Bayer Healthcare LLC	New Jersey, United States	Pharmaceutical medicine,Medicine,Computed tomography, ...[+2]	Patent: 12
12	Alexion Pharmaceuticals, Inc.	Connecticut, United States	Health care,Biopharmaceutical,Clinical trial, ...[+2]	Patent: 11
13	Bristol-Myers Squibb FCT bêta, Inc.	Texas, United States	Health care,Biological pathway,Biopharmaceutical, ...[+2]	Patent: 9
14	STARTUP Ligandal, Inc.	New York, United States	CRISPR,Coronavirus disease 2019 (COVID-19),Cell therapy, ...[+2]	Patent: 7
15	Duke University	North Carolina, United States	Style guide,Typeface,Medicine, ...[+2]	Patent: 7
16	Valerion Therapeutics LLC	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,Alglucosidase alfa, ...[+2]	Patent: 7
17	The Texas A&M University System	Texas, United States	University system,Asset management,Pension, ...[+2]	Patent: 7
18	Baylor College of Medicine	Texas, United States	Medical school,Medical education,Medicine, ...[+2]	Patent: 7
19	The Children's Medical Center Corp.	Massachusetts, United States	Internet of Things,Health care,Hospitality industry	Patent: 7
20	Icahn School of Medicine at Mount Sinai	New York, United States		Patent: 6
21	Vanderbilt University	Tennessee, United States	Professional degree,Health care,Publication, ...[+2]	Patent: 6
22	Rush University Medical Center	Illinois, United States	Health care,Surgical Specialty,Medicine, ...[+2]	Patent: 6
23	Marker Gene Technologies, Inc.	Oregon, United States	Biotechnology,Microarray,Marker gene, ...[+2]	Patent: 5
24	Dana-Farber Cancer Institute, Inc.	Massachusetts, United States	Pediatric cancer,Substance abuse,Robotics, ...[+2]	Patent: 5
25	New York University	New York, United States	Journalism,Professional studies,Medicine, ...[+2]	Patent: 5
26	Oklahoma Medical Research Foundation	Oklahoma, United States	Medical research,Health care,Biology, ...[+2]	Patent: 4
27	The University of Texas at Austin	Texas, United States	Undergraduate education,Career development,Association (object-oriented programming), ...[+2]	Patent: 4
28	St. Jude Children's Research Hospital, Inc.	Tennessee, United States	Health care,Hospitality industry,Genomics, ...[+2]	Patent: 4
29	Board of Trustees of the Leland Stanford Junior University	California, United States		Patent: 4
30	Sangamo Therapeutics, Inc.	California, United States	Cell,Pharmacy and Therapeutics,Genomics, ...[+2]	Patent: 4
31	University of Iowa Research Foundation	Iowa, United States	Gene delivery,Expression vector,Viral vector, ...[+2]	Patent: 4
32	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	Patent: 4
33	University of Massachusetts	Massachusetts, United States		Patent: 4
34	Merck Sharp & Dohme Corp.	New Jersey, United States	Prescription drug,Medicine,Stroke, ...[+2]	Patent: 4
35	The University of Texas at Arlington	Texas, United States	Library science,Community engagement,Critical thinker, ...[+2]	Patent: 4
36	Rexahn Pharmaceuticals, Inc.	United States	Medicine,Medical equipment,Drug, ...[+2]	Patent: 3
37	UbiVac, Inc.	Oregon, United States	Immunotherapy,Medicine,Wellness Programs, ...[+2]	Patent: 3
38	Northwest University	Washington, United States	Chemistry,Inorganic chemistry,Geochemistry, ...[+2]	Patent: 3
39	Ambrx, Inc.	California, United States	Biology,Pharmacy and Therapeutics,Dosing Frequency, ...[+2]	Patent: 3
40	Board of Regents of The University of Oklahoma	Oklahoma, United States	Radio broadcasting station,Radio broadcasting,Broadcasting	Patent: 3
41	Cincinnati Children's Hospital Medical Center	Ohio, United States	Health care,Pediatric trauma,Neonatology, ...[+2]	Patent: 3
42	The Johns Hopkins University	United States	History of the United States,Bequest,Medicine, ...[+2]	Patent: 3
43	Synageva BioPharma Corp.	Massachusetts, United States	Botanical drug,Herb,Accelerated atherosclerosis, ...[+2]	Patent: 2
44	Trustees of the University of Pennsylvania	Pennsylvania, United States	Academic Training,Educational institution,Graduate degree, ...[+2]	Patent: 2
45	Stony Brook University	New York, United States	Public university,Incubator,Accounting, ...[+2]	Patent: 2
46	Lysosomal Therapeutics, Inc.	Massachusetts, United States	Health care,Pharmacy and Therapeutics,Neurodegeneration, ...[+2]	Patent: 2
47	Yale University	Connecticut, United States	Health care,Social entrepreneurship,Association (object-oriented programming), ...[+2]	Patent: 2
48	Denali Therapeutics, Inc.	California, United States	Biotechnology,Pharmacy and Therapeutics,Biological process, ...[+2]	Patent: 2
49	Immunomic Therapeutics, Inc.	Pennsylvania, United States	Biology,Medicine,Pharmacy and Therapeutics, ...[+2]	Patent: 2
50	Georgetown University	District of Columbia, United States	Basketball,Medicine,Biotechnology, ...[+2]	Patent: 2