Top 50 Key Players companies in Calprotectin by Most Research Publications in the world in 2018 – Discovery

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The Calprotectin top 50 is Discovery PatSnap’ annual ranking of the top 50 Most Research Publications Calprotectin Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2018, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

Calprotectin is a complex of the mammalian proteins S100A8 and S100A9. In the presence of calcium, calprotectin is capable of sequestering the transition metals iron, manganese and zinc via chelation. This metal sequestration affords the complex antimicrobial properties. Calprotectin is the only known antimicrobial manganese sequestration protein complex. Calprotectin comprises as much as 60% of the soluble protein content of the cytosol of a neutrophil, and it is secreted by an unknown mechanism during inflammation. Faecal calprotectin has been used to detect intestinal inflammation (colitis or enteritis) and can serve as a biomarker for inflammatory bowel diseases and Rheumatoid Arthritis. Other names for calprotectin include MRP8-MRP14, calgranulin A and B, cystic fibrosis antigen, L1, 60BB antigen, and 27E10 antigen.

1	Oslo universitetssykehus HF	Oslo, Norway	Medical research,Health care,Oncology, ...[+2]	Literature: 18
2	Helsinki University Central Hospital	Finland	Medicine,Internal medicine,Surgery, ...[+2]	Literature: 16
3	Helse Bergen HF Haukeland Universitetssjukehus	Hordaland, Norway	Regional hospital,Oncology,Breast cancer, ...[+2]	Literature: 11
4	Universitätsspital Basel	Switzerland	Health care,Cell therapy,Monoclonal antibody, ...[+2]	Literature: 8
5	Glasgow Royal Infirmary		City centre	Literature: 5
6	Advanced Industrial Science & Technology	Tokyo, Japan	Graphene,Association (object-oriented programming)	Literature: 4
7	Umeå University	Vasterbottens Lan, Sweden	Microbiome,Biopharmaceutical	Literature: 4
8	Sheba Medical Center	Tel Aviv, Israel	Health care,Intubation,Tracheal tube, ...[+2]	Literature: 3
9	German Cancer Research Center	Baden-Württemberg, Germany	Cancer research,Biology,Cancer, ...[+2]	Literature: 3
10	Medisch Spectrum Twente	Overijssel, Netherlands	Health care,Hospitality industry	Literature: 3
11	Rambam Health Care Campus	Israel	Health care,Hospitality industry,Peacekeeping, ...[+2]	Literature: 3
12	Hospital Universitario La Paz	Madrid, Spain	Cardiovascular agent	Literature: 3
13	Instituto De SAlud Carlos Iii De Madrid	Spain	Cancer immunotherapy,Immunotherapy,Monoclonal antibody, ...[+2]	Literature: 3
14	VUmc	Noord-Holland, Netherlands	Enterprise mobility management,Health care	Literature: 3
15	Ghent University Hospital	Belgium	Flemish,Hospitality industry,Health care, ...[+2]	Literature: 3
16	London Research Institute	United Kingdom	Cancer research	Literature: 3
17	Novartis AG	Basel-Stadt, Switzerland	Dosage form,Health care,Medicine, ...[+2]	Literature: 2
18	AstraZeneca Plc	Cambridgeshire, United Kingdom	Medicine,Health care,Side effect, ...[+2]	Literature: 2
19	Max Planck Gesellschaft zur Förderung der Wissenschaften eV	Bayern, Germany	Basic research,Publishing,Market research, ...[+2]	Literature: 2
20	Sykehuset Innlandet HF	Hedmark, Norway	Mental health,Drug	Literature: 2
21	Stavanger University Hospital	Rogaland, Norway	Drug,Clinical research	Literature: 2
22	Near East University	Mersin, Turkey	Medicine,Computer science,Chemistry, ...[+2]	Literature: 2
23	Robarts Research Institute	Ontario, Canada	Medical research,Cancer	Literature: 2
24	Leids Universitair Medisch Centrum	Zuid-Holland, Netherlands	Medical research,Hospitality industry,Health care, ...[+2]	Literature: 2
25	Århus Universitetshospital	Denmark	Medical treatment,Hospitality industry,Health care, ...[+2]	Literature: 2
26	Analytica AB	Sweden	Nondestructive testing,Analytical Testing,Biological Testing	Literature: 2
27	Istituto Superiore di Sanità	Lazio, Italy	Association (object-oriented programming),Working group,Public institution, ...[+1]	Literature: 2
28	Ninewells Hospital	United Kingdom	Psychosurgery,Medical genetics,Laparoscopic surgery, ...[+2]	Literature: 2
29	Hitachi Ltd.	Tokyo, Japan	Elevator,Electrical equipment,Electric motor, ...[+2]	Literature: 1
30	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	Literature: 1
31	Nestlé SA	Vaud, Switzerland	Ice cream,Nutrition,Cosmetics, ...[+2]	Literature: 1
32	Thermo Fisher Scientific, Inc.	Massachusetts, United States	Biology,Medical equipment,Reagent, ...[+2]	Literature: 1
33	Trelleborg AB	Sweden	Mechanical engineering,Polymer,Microsphere, ...[+2]	Literature: 1
34	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	Literature: 1
35	Fonterra Co-operative Group Ltd.	Auckland, New Zealand	Nutrition,Dairy cattle,Whey protein, ...[+2]	Literature: 1
36	UCB SA	Belgium	Epilepsy,Adalimumab,Drug, ...[+2]	Literature: 1
37	Exponent, Inc.	California, United States	Expert witness,Legal proceeding,Manufacturing process, ...[+2]	Literature: 1
38	BBVA USA	Alabama, United States		Literature: 1
39	Mass General Brigham, Inc.	Massachusetts, United States	Health care,Medicine,Digital health, ...[+2]	Literature: 1
40	AgResearch Ltd.	Canterbury, New Zealand	Agriculture,Agricultural science,BCG vaccine, ...[+2]	Literature: 1
41	Teknologian Tutkimuskeskus VTT Oy	Southern Finland, Finland	Telecommunications,Applied research,Solar cell, ...[+2]	Literature: 1
42	Medical Park AG	Bayern, Germany	Health care,Pharmacy and Therapeutics,Traumatology, ...[+2]	Literature: 1
43	The Children's Mercy Hospital	Missouri, United States	Health care,Social network,Cancer immunotherapy, ...[+2]	Literature: 1
44	Janssen Pharmaceutica NV	Antwerpen, Belgium	Product design,Neuroscience,Health care, ...[+2]	Literature: 1
45	Sahlgrenska Universitetssjukhuset	Västra Götaland, Sweden	Health care,Hospitality industry,Patiromer, ...[+2]	Literature: 1
46	Gloucestershire Hospitals NHS Foundation Trust	Gloucestershire, United Kingdom	Data analysis,Health care,Hospitality industry	Literature: 1
47	Hopital Necker-Enfants Malades	Ile-de-France, France	Patiromer	Literature: 1
48	The Brigham & Women's Hospital, Inc.	Massachusetts, United States	Health care,Mitral valve surgery,Health equity, ...[+2]	Literature: 1
49	Herlev Hospital	Hovedstaden, Denmark	Health care,Cancer immunotherapy,Immunotherapy, ...[+2]	Literature: 1
50	The Mount Sinai Hospital	New York, United States	Borough,Health care,Hospitality industry, ...[+2]	Literature: 1