Top 50 Key Players companies in Connective tissue disease by Highest Patent Value in the world in 2018 – Discovery

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The Connective tissue disease top 50 is Discovery PatSnap’ annual ranking of the top 50 Highest Patent Value Connective tissue disease Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2018, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

A connective tissue disease (collagenosis) is any disease that has the connective tissues of the body as a target of pathology. Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds together, and protects organs. These tissues form a framework, or matrix, for the body, and are composed of two major structural protein molecules: collagen and elastin. There are many different types of collagen protein in each of the body's tissues. Elastin has the capability of stretching and returning to its original length—like a spring or rubber band. Elastin is the major component of ligaments (tissues that attach bone to bone) and skin. In patients with connective tissue disease, it is common for collagen and elastin to become injured by inflammation (ICT). Many connective tissue diseases feature abnormal immune system activity with inflammation in tissues as a result of an immune system that is directed against one's own body tissues (autoimmunity).

1	Nippon Shinyaku Co., Ltd.	Kyoto, Japan	Medicine,Health care,Functional food, ...[+2]	Avg patent value: 8.94 M
2	Bioniz Therapeutics, Inc.	California, United States	Medical equipment,Health care,Molecule, ...[+2]	Avg patent value: 7.83 M
3	Ferring International Center SA	VD, CH	Urology,Endocrinology,Obstetrics, ...[+2]	Avg patent value: 7.02 M
4	Biotie Therapies GmbH	Germany	Biotechnology,Agriculture,Fishery, ...[+2]	Avg patent value: 6.88 M
5	Endorecherche, Inc.	Canada		Avg patent value: 6.85 M
6	MediWound Ltd.	HaMerkaz, Israel	Chronic wound,Biotechnology,Medicine, ...[+2]	Avg patent value: 4.37 M
7	Laboratoires Expanscience SA	Île-de-France, France	Medicine,Health care,Glucosamine, ...[+2]	Avg patent value: 3.63 M
8	Global Blood Therapeutics, Inc.	California, United States	Pharmacy and Therapeutics,Medicine,Health care, ...[+2]	Avg patent value: 2.97 M
9	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	Avg patent value: 2.55 M
10	Astion Pharma A/S	Denmark	Clinical trial,Anti-inflammatory,Medicine, ...[+2]	Avg patent value: 2.51 M
11	Chong Kun Dang Pharmaceutical Corp.	South Korea	Medicine,Drug discovery,Drug development, ...[+2]	Avg patent value: 2.14 M
12	Tobira Therapeutics, Inc.	New Jersey, United States	Medicine,Health care,Pharmacy and Therapeutics, ...[+2]	Avg patent value: 1.77 M
13	Mesoblast, Inc.	New York, United States	Orthopedic disorders,Drug,Medicine, ...[+2]	Avg patent value: 1.43 M
14	STARTUP Oncoheroes Biosciences Inc	Massachusetts, United States	Drug,Medicine	Avg patent value: 710,000
15	Boehringer Ingelheim Pharmaceuticals, Inc.	Connecticut, United States	Central nervous system,Medicine,Drug, ...[+2]	Avg patent value: 710,000
16	Medtronic, Inc.	Minnesota, United States	Medicine,Implantable cardiac pacemaker,Biomedical engineering, ...[+2]	Avg patent value: 520,000
17	Shanghai Kexin Biotech Co., Ltd.	Shanghai Shi, China	Drug,Medicine,Recombinant antigen, ...[+2]	Avg patent value: 100,000
18	Angion Biomedica Corp.	New York, United States	Acute kidney injury,Medicine,Health care, ...[+2]	Avg patent value: 91,000
19	Chongqing Huapont Pharmaceutical Co. Ltd.	Chongqing Shi, China	Medicine,Pharmaceutical manufacturing,Allergy drugs, ...[+2]	Avg patent value: 75,000
20	Novartis AG	Basel-Stadt, Switzerland	Dosage form,Health care,Medicine, ...[+2]	Avg patent value: 69,000
21	Chengdu Tiantaishan Pharmaceutical Co., Ltd.	Sichuan Sheng, China	Somatostatin,Oncology drugs	Avg patent value: 56,000
22	J-Pharma Co., Ltd.	Kanagawa, Japan	Medicine,Drug,Hyperuricemia, ...[+2]	Avg patent value: 50,000
23	Sysmex Corp.	Hokkaido, Japan	Clinical chemistry,Reagent,Medical equipment, ...[+2]	Avg patent value: 20,000
24	Sunny Pharmtech Inc.	Taiwan Province, China	Drug development,Health care,Drug, ...[+2]	Avg patent value: 13,000
25	STARTUP Axolotl Biologix, Inc.	Arizona, United States	Biotechnology,Regenerative medicine,Health care	Avg patent value: 3,900
26	Bayer AG	Nordrhein-Westfalen, Germany	Health care,Biology,Chemical engineering, ...[+2]	Avg patent value: 0
27	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	Avg patent value: 0
28	AbbVie, Inc.	Illinois, United States	Health care,Medicine,Biopharmaceutical, ...[+2]	Avg patent value: 0
29	Takeda Pharmaceutical Co., Ltd.	Osaka, Japan	Medicine,Health care,Clinical trial, ...[+2]	Avg patent value: 0
30	Nippon Kayaku Co., Ltd.	Tokyo, Japan	Biosimilar,Chemical engineering,Industrial engineering, ...[+2]	Avg patent value: 0
31	Celgene Corp.	New Jersey, United States	Health care,Cytogenetic Abnormality,Medicine, ...[+2]	Avg patent value: 0
32	KYORIN Holdings, Inc.	Tokyo, Japan	Drug,Health care,Clinical trial, ...[+2]	Avg patent value: 0
33	Ono Pharmaceutical Co., Ltd.	Osaka, Japan	Diagnostic Reagent,Medicine,Health care, ...[+2]	Avg patent value: 0
34	Mitsubishi Tanabe Pharma Corp.	Osaka, Japan	Medicine,Health care,Toxoid, ...[+2]	Avg patent value: 0
35	Cipher Pharmaceuticals, Inc.	Ontario, Canada	Medicine,Health care,Core competency, ...[+2]	Avg patent value: 0
36	Kanebo Ltd.	Tokyo, Japan	Textile,Cosmetics,Food products, ...[+2]	Avg patent value: 0
37	KYORIN Pharmaceutical Co., Ltd.	Tokyo, Japan	Drug,Medicine,Cephalosporin, ...[+2]	Avg patent value: 0
38	Sanofi-Aventis Deutschland GmbH	Hessen, Germany	Biosimilar,Drug,Medicine	Avg patent value: 0
39	Fujisawa Pharmaceutical Co., Ltd.	Osaka, Japan	Drug,Medical equipment,Botanical drug, ...[+2]	Avg patent value: 0
40	Shenzhen YHLO Biotech Co., Ltd.	Guangdong Sheng, China	Medicine,Immunofluorescence,Supporting system, ...[+2]	Avg patent value: 0
41	Toyama Chemical Co., Ltd.	Tokyo, Japan	Pharmacy,Drug,Certolizumab pegol, ...[+2]	Avg patent value: 0
42	Aegera Therapeutics, Inc.	Quebec, Canada	Medicine,Health care,Neuropathic pain, ...[+2]	Avg patent value: 0
43	Science & Technology Corp.	Virginia, United States	Space Science,Aerospace engineering,Systems engineering, ...[+1]	Avg patent value: 0
44	Weber & Weber GmbH & Co. KG	Germany	Pharmacy	Avg patent value: 0
45	Takeda Chemical Industries Ltd.	Japan	Pharmaceutical drug,Botanical drug,Herb	Avg patent value: 0
46	Celtaxsys, Inc.	United States	Medicine,Health care,Cystic fibrosis, ...[+2]	Avg patent value: 0
47	Signal Pharmaceuticals LLC	California, United States	Intracellular signalling,Medicine,Intracellular, ...[+1]	Avg patent value: 0
48	STARTUP Timber Pharmaceuticals LLC	New Jersey, United States	Medicine,Localized Scleroderma,Congenital ichthyosis, ...[+2]	Avg patent value: 0
49	Ribozyme Pharmaceuticals	Colorado, United States	Ribozyme,Health care,RNA interference, ...[+2]	Avg patent value: 0
50	Sanofi-Aventis Ltd.	United Kingdom	Medicine,Thrombosis,Metabolic disorder, ...[+2]	Avg patent value: 0