Top 50 Key Players companies in Connective tissue disease by Most Patent Filings in the world in 2018 – Discovery

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The Connective tissue disease top 50 is Discovery PatSnap’ annual ranking of the top 50 Most Patent Filings Connective tissue disease Key Players in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2018, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

A connective tissue disease (collagenosis) is any disease that has the connective tissues of the body as a target of pathology. Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds together, and protects organs. These tissues form a framework, or matrix, for the body, and are composed of two major structural protein molecules: collagen and elastin. There are many different types of collagen protein in each of the body's tissues. Elastin has the capability of stretching and returning to its original length—like a spring or rubber band. Elastin is the major component of ligaments (tissues that attach bone to bone) and skin. In patients with connective tissue disease, it is common for collagen and elastin to become injured by inflammation (ICT). Many connective tissue diseases feature abnormal immune system activity with inflammation in tissues as a result of an immune system that is directed against one's own body tissues (autoimmunity).

1	Endorecherche, Inc.	Canada		Patent: 36
2	Chong Kun Dang Pharmaceutical Corp.	South Korea	Medicine,Drug discovery,Drug development, ...[+2]	Patent: 27
3	Tobira Therapeutics, Inc.	New Jersey, United States	Medicine,Health care,Pharmacy and Therapeutics, ...[+2]	Patent: 18
4	Astion Pharma A/S	Denmark	Clinical trial,Anti-inflammatory,Medicine, ...[+2]	Patent: 11
5	MediWound Ltd.	HaMerkaz, Israel	Chronic wound,Biotechnology,Medicine, ...[+2]	Patent: 8
6	Novartis AG	Basel-Stadt, Switzerland	Dosage form,Health care,Medicine, ...[+2]	Patent: 7
7	Toyama Chemical Co., Ltd.	Tokyo, Japan	Pharmacy,Drug,Certolizumab pegol, ...[+2]	Patent: 7
8	Boehringer Ingelheim Pharmaceuticals, Inc.	Connecticut, United States	Central nervous system,Medicine,Drug, ...[+2]	Patent: 6
9	Signal Pharmaceuticals, Inc.	California, United States	Transcription factor,Small molecule,Biotechnology, ...[+2]	Patent: 6
10	Shanghai Kexin Biotech Co., Ltd.	Shanghai Shi, China	Drug,Medicine,Recombinant antigen, ...[+2]	Patent: 5
11	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	Patent: 4
12	Mitsubishi Tanabe Pharma Corp.	Osaka, Japan	Medicine,Health care,Toxoid, ...[+2]	Patent: 4
13	Sanofi-Aventis Deutschland GmbH	Hessen, Germany	Biosimilar,Drug,Medicine	Patent: 4
14	Bayer AG	Nordrhein-Westfalen, Germany	Health care,Biology,Chemical engineering, ...[+2]	Patent: 3
15	Takeda Pharmaceutical Co., Ltd.	Osaka, Japan	Medicine,Health care,Clinical trial, ...[+2]	Patent: 3
16	Nippon Shinyaku Co., Ltd.	Kyoto, Japan	Medicine,Health care,Functional food, ...[+2]	Patent: 3
17	Medtronic, Inc.	Minnesota, United States	Medicine,Implantable cardiac pacemaker,Biomedical engineering, ...[+2]	Patent: 3
18	Weber & Weber GmbH & Co. KG	Germany	Pharmacy	Patent: 3
19	Takeda Chemical Industries Ltd.	Japan	Pharmaceutical drug,Botanical drug,Herb	Patent: 3
20	Mesoblast, Inc.	New York, United States	Orthopedic disorders,Drug,Medicine, ...[+2]	Patent: 3
21	Bayer Oy	Finland		Patent: 3
22	Global Blood Therapeutics, Inc.	California, United States	Pharmacy and Therapeutics,Medicine,Health care, ...[+2]	Patent: 2
23	Angion Biomedica Corp.	New York, United States	Acute kidney injury,Medicine,Health care, ...[+2]	Patent: 2
24	Shenzhen YHLO Biotech Co., Ltd.	Guangdong Sheng, China	Medicine,Immunofluorescence,Supporting system, ...[+2]	Patent: 2
25	Ribozyme Pharmaceuticals	Colorado, United States	Ribozyme,Health care,RNA interference, ...[+2]	Patent: 2
26	Boehringer Ingelheim Pharma GmbH	Austria	Proton-pump inhibitor,Antacid,Bevacizumab, ...[+2]	Patent: 2
27	Biotie Therapies GmbH	Germany	Biotechnology,Agriculture,Fishery, ...[+2]	Patent: 2
28	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	Patent: 1
29	AbbVie, Inc.	Illinois, United States	Health care,Medicine,Biopharmaceutical, ...[+2]	Patent: 1
30	Sysmex Corp.	Hokkaido, Japan	Clinical chemistry,Reagent,Medical equipment, ...[+2]	Patent: 1
31	Nippon Kayaku Co., Ltd.	Tokyo, Japan	Biosimilar,Chemical engineering,Industrial engineering, ...[+2]	Patent: 1
32	Celgene Corp.	New Jersey, United States	Health care,Cytogenetic Abnormality,Medicine, ...[+2]	Patent: 1
33	KYORIN Holdings, Inc.	Tokyo, Japan	Drug,Health care,Clinical trial, ...[+2]	Patent: 1
34	Ono Pharmaceutical Co., Ltd.	Osaka, Japan	Diagnostic Reagent,Medicine,Health care, ...[+2]	Patent: 1
35	Cipher Pharmaceuticals, Inc.	Ontario, Canada	Medicine,Health care,Core competency, ...[+2]	Patent: 1
36	Kanebo Ltd.	Tokyo, Japan	Textile,Cosmetics,Food products, ...[+2]	Patent: 1
37	KYORIN Pharmaceutical Co., Ltd.	Tokyo, Japan	Drug,Medicine,Cephalosporin, ...[+2]	Patent: 1
38	Fujisawa Pharmaceutical Co., Ltd.	Osaka, Japan	Drug,Medical equipment,Botanical drug, ...[+2]	Patent: 1
39	Sunny Pharmtech Inc.	Taiwan Province, China	Drug development,Health care,Drug, ...[+2]	Patent: 1
40	Laboratoires Expanscience SA	Île-de-France, France	Medicine,Health care,Glucosamine, ...[+2]	Patent: 1
41	Ferring International Center SA	VD, CH	Urology,Endocrinology,Obstetrics, ...[+2]	Patent: 1
42	Aegera Therapeutics, Inc.	Quebec, Canada	Medicine,Health care,Neuropathic pain, ...[+2]	Patent: 1
43	Science & Technology Corp.	Virginia, United States	Space Science,Aerospace engineering,Systems engineering, ...[+1]	Patent: 1
44	Chongqing Huapont Pharmaceutical Co. Ltd.	Chongqing Shi, China	Medicine,Pharmaceutical manufacturing,Allergy drugs, ...[+2]	Patent: 1
45	STARTUP Oncoheroes Biosciences Inc	Massachusetts, United States	Drug,Medicine	Patent: 1
46	STARTUP Axolotl Biologix, Inc.	Arizona, United States	Biotechnology,Regenerative medicine,Health care	Patent: 1
47	Celtaxsys, Inc.	United States	Medicine,Health care,Cystic fibrosis, ...[+2]	Patent: 1
48	Signal Pharmaceuticals LLC	California, United States	Intracellular signalling,Medicine,Intracellular, ...[+1]	Patent: 1
49	J-Pharma Co., Ltd.	Kanagawa, Japan	Medicine,Drug,Hyperuricemia, ...[+2]	Patent: 1
50	Bioniz Therapeutics, Inc.	California, United States	Medical equipment,Health care,Molecule, ...[+2]	Patent: 1