Top 50 Key Players companies in Lysosome by Most Patent Citation in the United States in 2020 – Discovery

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The Lysosome top 50 is Discovery PatSnap’ annual ranking of the top 50 Most Patent Citation Lysosome Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2020, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

A lysosome (/ˈlaɪsəˌsoʊm/) is a membrane-bound organelle found in many animal cells. They are spherical vesicles that contain hydrolytic enzymes that can break down many kinds of biomolecules. A lysosome has a specific composition, of both its membrane proteins, and its lumenal proteins. The lumen's pH (~4.5–5.0) is optimal for the enzymes involved in hydrolysis, analogous to the activity of the stomach. Besides degradation of polymers, the lysosome is involved in various cell processes, including secretion, plasma membrane repair, cell signaling, and energy metabolism.

1	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	patent citation: 1,746
2	Bristol Myers Co.	New York, United States	Botanical drug,Herb	patent citation: 1,746
3	Genzyme Corp.	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,Multiple sclerosis, ...[+2]	patent citation: 1,303
4	BioMarin Pharmaceutical, Inc.	California, United States	Software development,Biopharmaceutical,Clinical trial, ...[+2]	patent citation: 744
5	Virginia Tech Intellectual Properties, Inc.	Virginia, United States	Software,Medical imaging,Digital library, ...[+2]	patent citation: 259
6	Amicus Therapeutics, Inc.	New Jersey, United States	Pharmacological chaperone,Medicine,Health care, ...[+2]	patent citation: 194
7	Photocure ASA	New Jersey, United States	Photodynamic diagnosis,Medicine,Lifestyle drug, ...[+2]	patent citation: 181
8	Shire Human Genetic Therapies, Inc.	Massachusetts, United States	Medicine	patent citation: 143
9	UCSF Benioff Children's Hospital Oakland	California, United States	Substance abuse,Health care,Hospitality industry, ...[+2]	patent citation: 85
10	Maxygen, Inc.	California, United States	Directed evolution,DNA shuffling,Molecular breeding, ...[+2]	patent citation: 82
11	Medtronic, Inc.	Minnesota, United States	Medicine,Implantable cardiac pacemaker,Biomedical engineering, ...[+2]	patent citation: 80
12	Perseid Therapeutics LLC	California, United States	DNA shuffling,Medicine,Modalities	patent citation: 76
13	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	patent citation: 74
14	Biocept, Inc.	California, United States	Health care,Circulating tumor DNA,Circulating tumor cell, ...[+2]	patent citation: 73
15	Sarepta Therapeutics, Inc.	Massachusetts, United States	Pharmacy and Therapeutics,Health care,Approved drug, ...[+2]	patent citation: 53
16	ALZA Corp.	California, United States	Health care,Pharmacy and Therapeutics,Medical product, ...[+2]	patent citation: 49
17	Merck Sharp & Dohme Corp.	New Jersey, United States	Prescription drug,Medicine,Stroke, ...[+2]	patent citation: 48
18	Ambrx, Inc.	California, United States	Biology,Pharmacy and Therapeutics,Dosing Frequency, ...[+2]	patent citation: 48
19	PRP LLC	District of Columbia, United States	Alternative investment,Asset management	patent citation: 44
20	Kentucky BioProcessing LLC	Kentucky, United States	American tobacco,Chemical engineering	patent citation: 41
21	Pharmacia Corp.	New Jersey, United States	Botanical drug,Herb,Ophthalmology, ...[+2]	patent citation: 37
22	Ixsys, Inc.	California, United States	Software,Human resource management,Payroll	patent citation: 31
23	Massachusetts General Hospital	Massachusetts, United States	Substance abuse,Hospitality industry,Health care, ...[+2]	patent citation: 27
24	The General Hospital Corp.	Massachusetts, United States	Health care,Hospitality industry,Vascular Medicine, ...[+2]	patent citation: 27
25	Neuraltus Pharmaceuticals, Inc.	California, United States	Fabry's disease,Medicine,Health care, ...[+2]	patent citation: 27
26	STARTUP Prevail Therapeutics, Inc.	New York, United States	Gene,Health care,Pharmacy and Therapeutics, ...[+2]	patent citation: 27
27	Valerion Therapeutics LLC	Massachusetts, United States	Medicine,Pharmacy and Therapeutics,Alglucosidase alfa, ...[+2]	patent citation: 23
28	Bayer Healthcare LLC	New Jersey, United States	Pharmaceutical medicine,Medicine,Computed tomography, ...[+2]	patent citation: 22
29	Synageva BioPharma Corp.	Massachusetts, United States	Botanical drug,Herb,Accelerated atherosclerosis, ...[+2]	patent citation: 15
30	Research Development Foundation	United States	Plasmid,Molecular medicine,Cardiovascular agent, ...[+2]	patent citation: 15
31	Bristol-Myers Squibb FCT bêta, Inc.	Texas, United States	Health care,Biological pathway,Biopharmaceutical, ...[+2]	patent citation: 14
32	Enzon Pharmaceuticals, Inc.	New Jersey, United States	Medicine,Health care,PEGylation, ...[+2]	patent citation: 13
33	Arrogene, Inc.	California, United States	Cancer,Medicine,Drug	patent citation: 13
34	Arrogene	California, United States	Glioma,Pre-clinical development,Cancer	patent citation: 13
35	StemCells California, Inc.	California, United States		patent citation: 10
36	Alexion Pharmaceuticals, Inc.	Connecticut, United States	Health care,Biopharmaceutical,Clinical trial, ...[+2]	patent citation: 9
37	Panacea Pharmaceuticals, Inc.	United States	Medicine,Health care,Lymphokine, ...[+2]	patent citation: 8
38	Ocuphire Pharma, Inc.	Michigan, United States	OPHTHALMIC DISORDERS,Glaucoma,Eye drop, ...[+2]	patent citation: 8
39	Uwm Research Foundation, Inc.	Wisconsin, United States		patent citation: 7
40	Regeneron Pharmaceuticals, Inc.	New York, United States	Monoclonal antibody,Clinical trial,Cholesterol, ...[+2]	patent citation: 6
41	Nektar Therapeutics	California, United States	Biopharmaceutical,Chemical engineering,Health care, ...[+2]	patent citation: 6
42	Asklepios BioPharmaceutical, Inc.	North Carolina, United States	Biopharmaceutical,Health care,Gene delivery, ...[+2]	patent citation: 6
43	Rexahn Pharmaceuticals, Inc.	United States	Medicine,Medical equipment,Drug, ...[+2]	patent citation: 6
44	STARTUP Ligandal, Inc.	New York, United States	CRISPR,Coronavirus disease 2019 (COVID-19),Cell therapy, ...[+2]	patent citation: 6
45	Nektar Therapeutics AL Corp.	Alabama, United States	Ethylene glycol,Ethylene,Chemical engineering	patent citation: 6
46	Q Therapeutics, Inc.	Utah, United States	Medicine,Health care,Pharmacy and Therapeutics, ...[+2]	patent citation: 5
47	Horizon Orphan LLC	Illinois, United States	Medicine	patent citation: 5
48	Marker Gene Technologies, Inc.	Oregon, United States	Biotechnology,Microarray,Marker gene, ...[+2]	patent citation: 4
49	Hospira, Inc.	Illinois, United States	Medical equipment,Drug,Health care, ...[+2]	patent citation: 3
50	Cytokinetics, Inc.	California, United States	Cytoskeleton,Clinical trial,Medicine, ...[+2]	patent citation: 3