Top 50 Key Players companies in Proline by Most Patent Filings in the United States in 2022 – Discovery

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The Proline top 50 is Discovery PatSnap’ annual ranking of the top 50 Most Patent Filings Proline Key Players in the United States. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2022, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.

Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated NH₂⁺ form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO⁻ form under biological conditions), and a side chain pyrrolidine, classifying it as a nonpolar (at physiological pH), aliphatic amino acid. It is non-essential in humans, meaning the body can synthesize it from the non-essential amino acid L-glutamate. It is encoded by all the codons starting CC (CCU, CCC, CCA, and CCG).

1	Pfizer Inc.	New York, United States	Health care,Clinical trial,Drug, ...[+2]	Patent: 93
2	Merck & Co., Inc.	New Jersey, United States	Health care,Biopharmaceutical,Drug, ...[+2]	Patent: 63
3	Enanta Pharmaceuticals, Inc.	Massachusetts, United States	Medicine,Health care,Protease, ...[+2]	Patent: 61
4	Helix BioMedix, Inc.	Washington, United States	Peptide,Medical equipment,Medicine, ...[+2]	Patent: 41
5	American Can Co.	United States	Tin can,Packaging engineering,Microservices, ...[+1]	Patent: 40
6	Smithkline Beckman Corp	Pennsylvania, United States	Biotechnology,Medicine	Patent: 34
7	Los Alamos National Security LLC	New Mexico, United States	National security	Patent: 33
8	Bristol Myers Squibb Co.	New York, United States	Medicine,Health care,Oncology drugs, ...[+2]	Patent: 32
9	Amgen, Inc.	California, United States	Health care,Biopharmaceutical,TUMOR NECROSIS FACTOR BLOCKER, ...[+2]	Patent: 32
10	Bristol Myers Co.	New York, United States	Botanical drug,Herb	Patent: 32
11	Eli Lilly & Co.	Indiana, United States	Medicine,Health care,Humalog Mix, ...[+2]	Patent: 29
12	Bayer HealthCare Pharmaceuticals, Inc.	New Jersey, United States	Medicine,Cardiovascular agent,Clinical trial, ...[+2]	Patent: 28
13	Pfizer Products, Inc.	Connecticut, United States		Patent: 27
14	UAB Research Foundation	Alabama, United States	Biotechnology,Agriculture,Fishery, ...[+2]	Patent: 26
15	Schering Corp.	New Jersey, United States	Hepatitis,Medicine,Allergy	Patent: 24
16	Eolas Therapeutics, Inc.	California, United States	Addiction,Pharmacy and Therapeutics,Nicotine, ...[+2]	Patent: 19
17	Purdue Pharma LP	Connecticut, United States	Opioid,Medicine,Opioid epidemic, ...[+2]	Patent: 18
18	Purdue Pharma, Inc.	Connecticut, United States	Health care,Healthcare system,Educational program, ...[+1]	Patent: 18
19	bioMérieux, Inc.	North Carolina, United States	Medicine,Nucleic acid test,Blood Screening, ...[+2]	Patent: 18
20	Reata Pharmaceuticals, Inc.	Texas, United States	Inflammation,Medicine,Biopharmaceutical, ...[+2]	Patent: 17
21	Boehringer Ingelheim Animal Health USA, Inc.	United States	Medicine,Beta cell,Classical swine fever, ...[+2]	Patent: 17
22	Rhone Poulenc AG Co.	United States		Patent: 16
23	Givaudan Fragrances Corp.	New Jersey, United States	Cosmetics	Patent: 16
24	E.I. du Pont de Nemours & Co.	Delaware, United States	Agriculture,Materials science,Electronics, ...[+2]	Patent: 15
25	Genentech, Inc.	California, United States	Biotechnology,Biology,Medicine, ...[+2]	Patent: 15
26	Hill's Pet Nutrition, Inc.	Kansas, United States	Food packaging,Food products,Food industry, ...[+1]	Patent: 13
27	American Home Products LLC	California, United States	Forestry	Patent: 13
28	The Louver Shop	United States	Window shutter,Louver,Interior design	Patent: 13
29	Arena Pharmaceuticals, Inc.	California, United States	Health care,Clinical trial,Therapeutic Area, ...[+2]	Patent: 12
30	Miles, Inc.	Kansas, United States	Mobile app,Chemical engineering	Patent: 12
31	Mars, Inc.	Virginia, United States	Food products,Fast-moving consumer goods,Food industry, ...[+2]	Patent: 11
32	Excivion Ltd.	Massachusetts, United States	Biotechnology,Bionics,Blood cell, ...[+2]	Patent: 11
33	Cubist Pharmaceuticals LLC	Massachusetts, United States	Medicine,Health care,Meropenem, ...[+2]	Patent: 10
34	Vertex Pharmaceuticals, Inc.	Massachusetts, United States	Health care,Medicine,Cystic fibrosis, ...[+2]	Patent: 9
35	Phenomix Corp.	California, United States	Health care,Plant phenotyping,Greenhouse, ...[+2]	Patent: 9
36	ICI Americas, Inc.	Delaware, United States		Patent: 9
37	Protein Polymer Technologies, Inc.	California, United States	Polymer,Medicine,Biotechnology, ...[+2]	Patent: 9
38	STARTUP SyntheX, Inc.	California, United States	Biology,Medicine,Pharmacy and Therapeutics, ...[+2]	Patent: 9
39	Monsanto Technology LLC	Missouri, United States		Patent: 9
40	AbbVie, Inc.	Illinois, United States	Health care,Medicine,Biopharmaceutical, ...[+2]	Patent: 8
41	Artelo Biosciences, Inc.	California, United States	Endocannabinoid system,Biology,Biomedicine, ...[+2]	Patent: 8
42	3-D Matrix, Inc.	Massachusetts, United States	Health care,Self-assembling peptide,Wound healing, ...[+2]	Patent: 8
43	Incyte Pharmaceuticals, Inc.	California, United States	Biopharmaceutical,Medicine	Patent: 8
44	Colgate-Palmolive Co.	New York, United States	Toothpaste,Dental floss,Fast-moving consumer goods, ...[+2]	Patent: 7
45	Baxter International, Inc.	Illinois, United States	Clinical trial,Drug,Hemodialysis, ...[+2]	Patent: 7
46	MediVas LLC	California, United States	Medical equipment,Medicine,Therapeutic Devices, ...[+2]	Patent: 7
47	Boehringer Ingelheim Pharmaceuticals, Inc.	Connecticut, United States	Central nervous system,Medicine,Drug, ...[+2]	Patent: 7
48	Triad National Security LLC	Ohio, United States		Patent: 7
49	Wyeth LLC	New Jersey, United States		Patent: 7
50	Danisco US, Inc.	Delaware, United States	Synthetic rubber,Bioplastic,Plasticizer, ...[+2]	Patent: 7