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Top 50 Startups & Unicorns companies in Monoclonal antibody
by Highest Patent Value in the world in 2021

The Monoclonal antibody top 50 is Discovery PatSnap’ annual ranking of the top 50 Highest Patent Value Monoclonal antibody Startups & Unicorns in the world. Discovery has identified the top key players, startups & unicorns, fast-growings, news entrants in 2021, ranking from differnt perspectives, including patent filing intensity, academic research capability, news media heat. The company list is generated from various data types.
Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell. Monoclonal antibodies can have monovalent affinity, in that they bind to the same epitope (the part of an antigen that is recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different plasma cell (antibody secreting immune cell) lineages. Bispecific monoclonal antibodies can also be engineered, by increasing the therapeutic targets of one single monoclonal antibody to two epitopes.
#
Company Name
Region
Tech Topics
Total
1
Viscosity,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 9.08 M
2
Medicine,Medical equipment,Health care,
...[+2]
Avg patent value: 8.43 M
3
Immunotherapy,Health care,Clinical trial,
...[+2]
Avg patent value: 8.02 M
4
Avg patent value: 6.24 M
5
Clinical trial,Medicine,Health care,
...[+2]
Avg patent value: 4.30 M
6
Cancer vaccine,Pharmacy and Therapeutics,Biotechnology,
...[+2]
Avg patent value: 3.15 M
7
Rhône-Alpes, France
Monoclonal antibody,Health care,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 2.88 M
8
Medicine,Pharmacy and Therapeutics,Cell therapy,
...[+2]
Avg patent value: 2.83 M
9
Avg patent value: 2.48 M
10
Herefordshire, United Kingdom
Avg patent value: 2.39 M
11
Avg patent value: 1.85 M
12
Pharmacy and Therapeutics,Monoclonal antibody,Antibody,
...[+2]
Avg patent value: 1.77 M
13
Health care,Pharmacy and Therapeutics,Oncology drugs,
...[+2]
Avg patent value: 1.50 M
14
Avg patent value: 1.33 M
15
Avg patent value: 1.26 M
16
Aprogen
Avg patent value: 1.14 M
17
Abruzzi, Italy
Avg patent value: 1.02 M
18
Southern Finland, Finland
Cancer immunotherapy,Medicine,Health care,
...[+2]
Avg patent value: 960,000
19
Avg patent value: 940,000
20
Medicine,Health care,Cancer,
...[+2]
Avg patent value: 720,000
21
Avg patent value: 698,571
22
Avg patent value: 542,500
23
Avg patent value: 540,000
24
Tokyo, Japan
Antibody,Medicine,Molecule,
...[+2]
Avg patent value: 497,400
25
Alberta, Canada
Avg patent value: 471,333
26
Avg patent value: 435,294
27
Avg patent value: 430,000
28
Emilia-Romagna, Italy
Health care,Cell,Drug,
...[+2]
Avg patent value: 280,000
29
Liquid biopsy,Health care
Avg patent value: 230,000
30
Biopharmaceutical,Medicine,Health care,
...[+2]
Avg patent value: 220,000
31
Avg patent value: 180,000
32
Utrecht, Netherlands
Avg patent value: 173,325
33
Medicine,Health care,Diagnostic Reagent,
...[+2]
Avg patent value: 128,571
34
Salubris Biotherapeutics, Inc.
Avg patent value: 100,000
35
Angiogenesis,Biology,Pharmacy and Therapeutics,
...[+2]
Avg patent value: 100,000
36
Avg patent value: 99,000
37
Medicine,Pharmacy and Therapeutics,Autoimmune disease,
...[+2]
Avg patent value: 90,000
38
Health care,Cell,Hematological neoplasm,
...[+2]
Avg patent value: 76,850
39
Herefordshire, United Kingdom
Avg patent value: 75,057
40
Victoria, Australia
Avg patent value: 66,000
41
Hangzhou Sumgen Biotech Co., Ltd.
Avg patent value: 64,000
42
Gene,Biology,Health care,
...[+2]
Avg patent value: 63,000
43
Pharmacy and Therapeutics,Biomedicine,Biotechnology,
...[+2]
Avg patent value: 62,288
44
Niedersachsen, Germany
Avg patent value: 58,000
45
Jerusalem, Israel
Avg patent value: 49,000
46
Avg patent value: 48,200
47
Avg patent value: 47,085
48
Pharmacy and Therapeutics,Health care,Biotechnology,
...[+2]
Avg patent value: 45,000
49
Avg patent value: 39,200
50
HaZafon, Israel
Medicine,Breakthrough therapy,Cancer immunotherapy,
...[+2]
Avg patent value: 39,000
Page generation time: Jul 18 2025