Janssen Pharmaceutica is a pharmaceutical company headquartered in Beerse, Belgium and owned by Johnson & Johnson. It was founded in 1953 by Paul Janssen. In 1961, Janssen Pharmaceutica was purchased by New Jersey-based American corporation Johnson & Johnson, and became part of Johnson & Johnson Pharmaceutical Research and Development (J&J PRD), now renamed to Janssen Research and Development (JRD), which conducts research and development activities related to a wide range of human medical disorders, including mental illness, neurological disorders, anaesthesia and analgesia, gastrointestinal disorders, fungal infection, HIV/AIDS, allergies and cancer. Janssen and Ortho-McNeil Pharmaceutical have been placed in the Ortho-McNeil-Janssen group within Johnson & Johnson Company.

Novartis AG is a holding company, which engages in the development, manufacture, and marketing of healthcare products. It operates through the following segments: Innovative Medicines, Sandoz, and Corporate. The Innovative Medicines segment researches, develops, manufactures, distributes and sells patented pharmaceuticals, and is composed of two business units: Novartis Oncology and Novartis Pharmaceuticals. The Sandoz segment develops, manufactures and markets finished dosage form medicines as well as intermediary products, including active pharmaceutical ingredients. The Corporate segment refers to group management and central services. The company was founded on February 29, 1996 and is headquartered in Basel, Switzerland.

Otsuka Holdings operates in pharmaceuticals, nutraceuticals, and consumer products. The business activity of the company includes providing healthcare solutions in the areas of the nervous system, oncology, cardiovascular system, respiratory system, infectious disease, and others. The company engages in the research and development of functional foods and beverages, such as electrolyte drinks, nutritional foods, soy snacks, and dietary foods.

Nippon Zoki Pharmaceutical Co. Ltd. is a private company headquartered in Chuo-ku, Japan, that manufactures pharmaceutical products.

Rohto Pharmaceutical Co. Ltd. engages in the manufacture and sale of pharmaceutical products, cosmetics, and functional food items. Its products include eye drops, contact lens care, dermal medicines, skin care, internal medicines, cold remedies, test kits, and denture cleansers. Its operations are carried out through the following segments: Japan, America, Europe, Asia, and Others. The company was founded by Anmin Yamada on February 22, 1899 and is headquartered in Osaka, Japan.

Taisho Pharmaceutical Co., Ltd. engages in the manufacture and sale of pharmaceutical products. It operates through the following divisions: Self-Medication, Prescription Pharmaceutical and Overseas Development. The Self-Medication division deals with the research, development, and production of over-the-counter (OTC) drugs, medical supplies, food for specific health use, and hygiene products. The Prescription Pharmaceutical division handles research and development of new drugs in the fields of central nervous system diseases, metabolic diseases, infectious diseases, and inflammatory diseases. The Overseas Development division markets energy drinks and OTC pharmaceuticals overseas. The company was founded on October 12, 1912 and is headquartered in Tokyo, Japan.

The Upjohn Company was a pharmaceutical manufacturing firm founded in 1886 in Kalamazoo, Michigan, by Dr. William E. Upjohn, an 1875 graduate of the University of Michigan medical school. The company was originally formed to make friable pills, which were specifically designed to be easily digested. These could be "reduced to a powder under the thumb", a strong marketing argument at the time.

J. Uriach y Cia SA manufactures and markets pharmaceutical products. It offers consumer health products, including over-the-counter drugs, food supplements, personal health and wellbeing products, and nutricosmetic products. The company was founded by Juan Uriach Feliu in 1838 and is headquartered in Barcelona, Spain.

Kowa Co., Ltd. engages in trading of textiles, machinery, and construction materials. The company also manufactures and sells medicines, medical equipment, and energy saving products. It operates through the following business divisions: Pharmaceutical, Medical Device, Foods, General Trading, Lifestyle Business, and Hospitality. The company was founded on December 25, 1894 and is headquartered in Nagoya, Japan.

Fisons plc was a British multinational pharmaceutical, scientific instruments and horticultural chemicals company headquartered in Ipswich, United Kingdom. It was listed on the London Stock Exchange and was once a constituent of the FTSE 100 Index. It was acquired by Rhone-Poulenc in 1995.

CLL Pharma SA develops and manufactures generic drugs and galenical formulations. It offers products for the treatment of cardiovascular, allergy, neurology, infection, pain, anti-inflammatory, psychiatry, endocrine, and skin diseases and infections. The company was founded by Claude Laruelle in 1995 and is headquartered in Nice, France.

Wholesales pharmaceutical products

Nihon Nohyaku Co., Ltd. engages in the manufacture of agrochemical and pharmaceutical products. It operates through the following segments: Agrochemical, Chemical Products (except agrochemical), and Others. The Agrochemical segment produces and sells insecticides, fungicides, herbicides, pesticides, and other agrochemicals. The Chemical Products segment manufactures and distributes wood chemicals, water treatment agents, agrochemical materials, and pharmaceutical products. The Others segment deals with landscaping and greening construction, real estate leasing, logistics services, and pesticide residue analysis. The company was founded on November 17, 1928 and is headquartered in Tokyo, Japan.

Schering Corp. manufactures pharmaceutical products. It offers products in the areas of allergy and respiratory, anti-infectives, foot care, hepatitis, skin disorders, and sun care. It is a subsidiary of Schering-Plough Corp. The company is headquartered in Kenilworth, NY.

Part of Abbott Laboratories, Hokuriku Seiyaku Co., Ltd. is a Japanese company located in Katsuyama. The firm develops, manufactures, and sells pharmaceuticals. On June 30, 2002 Abbott Laboratories acquired Hokuriku Seiyaku Co., Ltd. for $291.31 million.

Nidaria Technology Ltd. develops jellyfish repellent products. Its research and development center is based in its corporate headquarters so that its research professionals can be integrally involved in high-level company decisions. The company was founded by Tamar Lotan in 1995 and is headquartered in Jordan Valley, Israel.

Smith Kline & French Laboratories Ltd. manufactures pharmaceutical products. The company is headquartered in Brentford, the United Kingdom.

Hisamitsu Pharmaceutical Co., Ltd, a subsidiary of Hisamitsu Pharmaceutical Co., Inc., is a Taiwanese company located in Taipei. The firm manufactures and markets pharmaceuticals.