Edwards Lifesciences Corp. engages in patient-focused medical innovations for heart disease and critical care monitoring. Its products are categorized into four main areas: Transcatheter Aortic Valve Replacement, Transcatheter Mitral and Tricuspid Therapies, Surgical Structural Heart, and Critical Care. It operates through the following geographical segments: United States, Europe, Japan, and Rest of World. The company was founded by Miles Lowell Edwards in 1958 and is headquartered in Irvine, CA.

Medtronic, Inc. operates as a medical technology company. It offers implantable cardiac pacemakers, eternal defibrillators, inferior turbinate surgery products, and continuous glucose monitoring device. The company was founded by Earl E. Bakken and Palmer J. Hermundslie on April 29, 1949 and is headquartered in Minneapolis, MN.

Part of Edwards Lifesciences Corp., Edwards Lifesciences PVT, Inc. is a company headquartered in the United States that supplies medical equipment.

St. Jude Medical, Inc. was an American global medical device company headquartered in Little Canada, Minnesota, U.S., a suburb of Saint Paul. The company had more than 20 principal operations and manufacturing facilities worldwide with products sold in more than 100 countries. Its major markets include the United States, Europe, Latin America and Asia-Pacific. The company was named after Jude the Apostle, the patron saint of lost causes.

Traverse Partners LLC, a subsidiary of Hovnanian Enterprises, Inc., is a company headquartered in Mooresville, NC. The firm provides investment advice. It was founded by Jeff Janer.

HeartWare, Inc. manufactures electro medical and electrotherapeutic apparatus. The company develops implantable circulatory assist devices, which are used in treating patients with congestive heart failure problems. The company was established in 2003 and is headquartered in Miramar, FL

JenaValve Technology GmbH develops and manufactures transcatheter valve implantation systems for transapical and transfemoral implantation. The firm offers a therapeutic alternative to surgical aortic valve replacement for high-risk patients suffering from aortic heart valve stenosis. The company was founded by Markus Ferrari, Volker Guyenot and Hans-Reiner Figulla in 2006 and is headquartered in Munich, Germany.

Magenta Medical Ltd. develops medical devices for the treatment of acute and congestive heart failure. It offers a temporary venous catheter-based therapy for hospital-admitted patients. The firm’s novel therapeutic principle is aimed at addressing renal venous congestion and its deleterious effects on renal and cardiac function that is a pathophysiological core element of acute heart failure. The company was founded by Ehud Schwammenthal and Yosi Tuval in October 2012 and is headquartered in Kadima, Israel.

BioStable is a cardiovascular device company that develops innovative new products for the treatment of cardiovascular diseases. The company is led by an experienced group of industry executives with expertise in rapid and effective medical device development. The organization incorporates core strengths in all areas of product development including quality systems, design, engineering, prototyping and pilot production, in-vitro and in-vivo testing, manufacturing, global regulatory relationships, clinical product validation, market launch, and distribution. BioStable provides a competitive edge by minimizing time to market for cost-effective medical devices that deliver improved clinical outcomes. The company focused on developing and commercializing proprietary valve repair technologies that provide an alternative to valve replacement for patients with aortic valve disease. BioStable was founded in

Part of Edwards Lifesciences Corp., Edwards Lifesciences LLC is a company headquartered in Irvine, CA. The firm develops and manufactures heart valves and hemodynamic monitoring systems. It was founded in 1958. Michael A. Mussallem has been the CEO since 2000.

Heartport is an entrepreneurial medical device maker that has introduced several innovative systems for conducting less-invasive cardiac surgery. The company was founded by John H. Stevens and Wesley D. Sterman. Heartport manufactures and markets less invasive cardiac surgery products that enable surgeons to perform a wide range of less invasive open-chest and minimally invasive heart operations, including stopped heart and beating heart procedures. In April 2001, Heartport was merged with and into CARDIOVATIONS, a wholly-owned subsidiary of Johnson & Johnson. Heartport continues to operate as a part of the division of Ethicon, Inc., a Johnson & Johnson company. Ethicon is a global leader in developing and marketing products for surgery in the areas of wound closure and wound management, surgical sports medicine, women's health and cardiovascular surgery.

Silk Road Medical believes that by innovating around proven surgical principles and developing breakthrough technology for vascular specialists, we can improve the lives of people with arterial disease. Our history is one of deep collaboration with vascular surgeons and our future will be guided by continuous learning, observation, and improvement. Silk Road advances patient care. Silk Road Medical Inc. was founded in 2007 and is based in Sunnyvale, California.

Boston Scientific Scimed, Inc. develops, manufactures, and markets medical devices used principally to treat cardiovascular disease.

Silence Therapeutics GmbH, a subsidiary of Silence Therapeutics Plc, is a German company located in Berlin that operates biotechnology company to develops RNAi-based drugs. The firm was founded in 2014.

CorMatrix Cardiovascular is a privately held medical device company that is dedicated to developing and delivering innovative biomaterial devices that harness the body’s own innate ability to repair damaged heart tissue. The company is currently researching, developing, and commercializing a platform technology, known as CorMatrix ECM, for a variety of cardiovascular indications. Incorporated in December of 2001, CorMatrix was co-founded by David Camp, an entrepreneurial executive in the cardiovascular medical device field, and Robert G. Matheny, MD, a cardiothoracic surgeon and co-inventor on several patents related to extracellular matrix (ECM) technology. Dr. Matheny’s interest and experience with these unique materials began at Purdue University in the 1990s while he was a private practice cardiac surgeon in Indianapolis. Realizing the potential of extracellular matrix materials for cardiovascular surgery, he further increased his study and preclinical work in matrix materials and tissue repair.

Thoratec Corp. develops, manufactures and markets proprietary medical devices used for circulatory support for the treatment of heart failure patients. The company's products include Ventricular Assist Devices, HeartMate Left Ventricular Assist System, HeartMate II Left Ventricular Assist System, Thoratec Paracorporeal Ventricular Assist Device and Thoratec Implantable Ventricular Assist. It also manufactures and markets the CentriMag Acute Circulatory System, HeartMate II, PVAD, IVAD and for pediatric patients PediMag/PediVAS Acute Circulatory System. Its ventricular assist devices products primarily serve patients suffering from late-stage heart failure. Heart Failure is a chronic disease that occurs when degeneration of the heart muscle reduces the pumping power of the heart, causing the heart to become too weak to pump blood at a level sufficient to meet the body's demands. The company operates its business through the Cardiovascular group segment, which develops, manufactures mechanical circulatory products to support the cardiovascular systems of humans and to provide product-related services. Thoratec was founded in March 1976 and is headquartered in Pleasanton, CA.

Fu Wai Hospital, founded in 1956.