Synthesis BV engages in the design and production of synthetic water level regulation products. It offers penstocks, pipeline valves, accessories, channel slide gates, fish migration, float units, overflow pits, pivoted weirs, pipes, dirt grates, butterfly valve, and check valves. The company is headquartered in Emmeloord, the Netherlands.

DePuy Synthes Products, Inc. develops and markets medical products. It offers distal volar Radius, which is designed to treat distal radius fractures, dorsal endoplate, an invasive dorsal nail plate that provides fixed angle support and intramedullary locked fixation with a duplicate and reproducible surgical procedure, spatial subchondral support plate, which is used to treat proximal humeral fractures and Small Bone Fixation System, a percutaneous locked intramedullary nail system for metacarpals and the phalanges. The company was founded on June 22, 2004 and is headquartered in Wilmington, DE.

Synthes USA LP used to manufacture medical devices. The company was founded by Hansjörg Wyss in 1974 and is headquartered in West Chester, PA.

Part of Zimmer Biomet Holdings, Inc., Biomet CV is a Dutch company. The firm manufactures medical instrument and aids.

Smith & Nephew PLC designs, manufactures and markets orthopedic devices, sports medicine and ENT technologies, and wound-care solutions. Slightly more than 40% of the U.K.-based firm's revenue comes from orthopedic products, and another 30% is a sports medicine and ENT. The remaining 27% of revenue is from the advanced wound therapy segment. Roughly half of Smith & Nephew's total revenue comes from the United States, just over 30% is from other developed markets, and emerging markets account for the remainder.

Globus Medical, Inc. operates as a medical device company that develops and commercializes healthcare solutions. The firm engages in developing products that promote healing in patients with musculoskeletal disorders. It classifies products into Innovative Fusion and Disruptive Technology. It operates through the United States and International geographical segments. The company was founded by David C. Paul, David D. Davidar and Andrew Iott in March 2003 and is headquartered in Audubon, PA.

Aesculap AG engages in the development, manufacture, and distribution of precision, medical, as well as medical technology instruments. It also offers medical apparatus, prostheses, implants, suture materials, laboratory and hospital supplies, as well as equipment for the manufacture of medical and medical technology devices. The company was founded in 1867 and is headquartered in Tuttlingen, Germany.

Acumed, LLC is a medical device manufacturer that provides orthopaedic and medical solutions that improve patient care around the world. The company is headquartered in Hillsboro, Oregon, with a global distribution network and offices worldwide Acumed is a multi-award-winning company, dedicated to innovative and quality medical device solutions. We are committed to the highest standards of manufacturing and proudly produce over 90% of our implants in the U.S.

Part of Medtronic Plc, Warsaw Orthopedic, Inc. is a company headquartered in the United States that operates orthopedic center.

Zimmer, Inc. provides joint replacement solutions. The firm products include trauma and dental implants and orthopaedic surgical products. The company was founded in 1927 and is headquartered in Warsaw, IN.

DePuy Products, Inc., part of Johnson & Johnson, is a company headquartered in the United States. The firm manufactures and distributes orthopaedic devices.

Medartis Holding AG engages in the development, manufacture, and sale of medical devices for surgical fixation of bone fractures. Its product category includes fixation system and technology for upper and lower extremities, cranio-maxillofacial, CMX, and KeriMedical. It operates through the following geographical segments: Europe, Middle East, and Africa; Asia Pacific; Latin America; and North America. The company was founded by Thomas Straumann on November 3, 1997 and is headquartered in Basel, Switzerland.

Biomet Manufacturing LLC manufactures and markets surgical and non-surgical products. The firm operates in one reportable business segment musculoskeletal products, which includes the design, manufacture and marketing of products in five product categories large joint reconstructive, sports, extremities, trauma spine and bone Healing, and dental products. The company is headquartered in Warsaw, IN.

Paragon 28, Inc. engages in operation of an orthopedic foot and ankle company. Its products include bone graft harvest system, bone marrow aspirate kits, and soft tissue fixation system. The company was founded by Albert DaCosta, Frank Bono, Jim Riegler and Lee Rosenthal in 2010 and is headquartered in Englewood, CO.

aap Implantate AG is a global medical technology company. aap Implantate develops, manufactures and markets orthopedic trauma products. In addition to the innovative anatomical plate system LOQTEQ® and trauma-complementary biomaterials, the company's IP-protected portfolio includes a wide range of self-tapping screws as well as standard plates and screws.

Arthrex GmbH, a subsidiary of Arthrex, Inc., is a German company located in Munich that manufactures orthopedic devices. Stefan Krupp is currently the CEO of the firm.

Stryker European Holdings I LLC, part of Stryker Corp., is an American company providing investment services.