Pi-Cardia is a medical device start-up company developing a novel low profile catheter for the treatment of aortic stenosis. The company's proprietary technology is based on delivering mechanical impact for creating fractures in valve calcifications, without injuring the surrounding soft tissue. This treatment, which only takes several seconds, is intended to increase the valve effective orifice area without the need to replace the valve.

ReLeaf Medical Ltd. develops medical devices to treat calcification related diseases. The company was founded by Moshe Y. Flugelman and Yael Nir in September 2006 and is headquartered in Kiryat Shmona, Israel.

Shockwave Medical is developing the Lithoplasty™ family of balloon dilatation catheters that incorporate tiny lithotripsy electrodes designed to increase the compliance of rigid vascular and valvular lesions prior to low-pressure dilation, thereby limiting injury to healthy tissue and overcoming significant limitations of current revascularization technologies. The technology is built on traditional balloon catheter platforms rendering it inherently familiar and easy to use for cardiologists, interventional radiologists and vascular surgeons alike. In peripheral vessels, Lithoplasty™ could enable more effective angioplasty, less frequent bailout stent usage and enhanced lesion preparation prior to the use of drug eluting balloons (DEB) or bio-absorbable vascular scaffolds (BVS). In coronary vessels it could facilitate stent delivery and enhance vessel preparation prior to stent or BVS placement. Finally, in aortic valves the technology could vastly improve native tissue preparation prior to trans-catheter aortic valve replacement (TAVR) and valvuloplasty for those patients not suitable for TAVR.

Biomedical Braille company develops and manufactures products in the Cardiovascular, Biological, Electromedical, Endovascular, Transcatheter, and Oncology lines, fruits of the aggregate technology applied to other areas of Medicine, with an institutional mission to develop innovative technologies that reduce the global cost of health and are accessible to the population with the main purpose of caring for people.

Direct Flow Medical, Inc. develops transcatheter heart valve technologies. It explores application of its technology beyond the aortic valve, to the mitral valve, and other valve anatomy. The firm’s Transcatheter Aortic Valve System is indicated for the treatment of patients with severe aortic stenosis, who are at risk for surgical aortic valve replacement. The company's system incorporates a polymer frame, which is expanded using pressurized saline and contrast for placement, assessment and repositioning. Direct Flow Medical was founded by Gordon B. Bishop and Randall T. Lashinski in June 2004 and is headquartered in Santa Rosa, CA.

Shanghai Shape Memory Alloy Co., Ltd. engages in the research and development, production, and marketing of occluders and vascular plugs. Its business activities include development of shape memory alloys, production of embolism equipment, and export and import business. The company was founded on May 5, 1994 and is headquartered in Shanghai, China.

Tokai Medical Products is a R&D-type company that continues to create value in the field of advanced medical devices.

Zhejiang Jierxin Medical Technology Co., Ltd., established on 2021-06-24, Business scope includes general items:Technical Services,technology development,technical consulting,Technology Exchange,technology transfer,Technology Promotion;Sales of Class II Medical Devices;Rubber Products Sales;Sales of plastic products;Metal Products Sales(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license).licensed items:Production of Class II Medical Devices;Production of Class III Medical Devices;Class III medical device business;Import and export;Technology Import and Export(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments,Specific business projects are subject to approval results).

Hitachi Kokusai Electric, Inc. engages in the development of semiconductor manufacturing, broadcasting, video and communication systems. It operates through the following segments: Video and Wireless Network Solutions; Eco and Thin Film Processing Solutions; and Others. The Video and Wireless Network Solutions segment manufactures wireless communication systems, information solutions, broadcasting systems, surveillance cameras and industrial video cameras. The company was founded on November 17, 1949 and is headquartered in Tokyo, Japan.

Wuhan Center Hospital is a Chinese private company located in Wuhan that engages in providing general medical and surgical services and other hospital services.

The University of California is the nation's best public university system, delivering top-notch research and innovation to California (and the world).