The cell cycle, or cell-division cycle, is the series of events that take place in a cell leading to duplication of its DNA (DNA replication) and division of cytoplasm and organelles to produce two daughter cells. In bacteria, which lack a cell nucleus, the cell cycle is divided into the B, C, and D periods. The B period extends from the end of cell division to the beginning of DNA replication. DNA replication occurs during the C period. The D period refers to the stage between the end of DNA replication and the splitting of the bacterial cell into two daughter cells. In cells with a nucleus, as in eukaryotes, the cell cycle is also divided into two main stages: interphase and the mitotic (M) phase (including mitosis and cytokinesis). During interphase, the cell grows, accumulating nutrients needed for mitosis, and undergoes DNA replication preparing it for cell division. During the mitotic phase, the replicated chromosomes and cytoplasm separate into two new daughter cells. To ensure the proper division of the cell, there are control mechanisms known as cell cycle checkpoints.
AstraZeneca Pharmaceutical Co., Ltd.
http://www.astrazeneca.com.cn
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AstraZeneca has always believed in science, inspires infinite possibilities, and puts science at the top of all work. AstraZeneca's strategically important core treatment areas, and are committed to exploring pathogenic mechanisms, treatment methods, and innovative drugs, so that science can change people's lives and bring it to the medical industry Significant changes.
Amgen Inc. (formerly Applied Molecular Genetics Inc.) is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California. In 2018, the company's largest selling product lines were Neulasta, an immunostimulator used to prevent infections in patients undergoing cancer chemotherapy and Enbrel, a tumor necrosis factor blocker used in the treatment of rheumatoid arthritis and other autoimmune diseases. Other products include Epogen, Aranesp, Sensipar/Mimpara, Nplate, Vectibix, Prolia and XGEVA.
Biopharmaceutical
TUMOR NECROSIS FACTOR BLOCKER
Medicine
Cancer chemotherapy
Molecular genetics
Rheumatoid arthritis
Autoimmune disease
Oncology drugs
Monoclonal antibody
Clinical trial
Immunotherapy
Bevacizumab
Cardiovascular agent
Adalimumab
Biosimilar
Genomics
Cancer immunotherapy
Antibody
Rituximab
Rigel Pharmaceuticals, Inc.
Rigel Pharmaceuticals, Inc. operates as a clinical stage biotechnology company. It discovers and develops novel, targeted drugs in the therapeutic areas of immunology, oncology and immune oncology. The firm focuses on intracellular signalling pathways and related targets that are critical to disease mechanisms. The company's products include Tavalisse, Fostamatinib and R835. Rigel Pharmaceuticals was founded by Donald G. Payan, James M. Gower, Thomas A. Raffin, Garry P. Nolan and Ronald B. Garren on June 14, 1996 and is headquartered in South San Francisco, CA.
Pharmacy and Therapeutics
Fostamatinib
Biotechnology
Oncology
Intracellular signaling pathways
Clinical trial
Drug
Rituximab
Autoimmune disease
Therapeutic Area
Tocilizumab
Biomedicine
Cancer
Corticosteroid
Enzyme
Glomerulonephritis
Graft-versus-host disease
Spondyloarthropathy
Rheumatoid arthritis
Toll-like receptor
CropDesign NV
http://www.cropdesign.com
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CropDesign NV develops traits for cereal crops. It delivers agronomic traits for the global commercial seed markets. The firm focuses on enhancing grain yield in crops such as corn and rice, and increasing biomass of energy crops. Its platform, TraitMill, lows evaluating the effect of genes on the performance of plants under different growing conditions, including drought and low nutrient stress. The company was founded in 1998 and is headquartered in Zwijnaarde, Blgium.
Crop
Agriculture
Grain yield
Energy crop
Gene
Biomass
The Board of Regents of The University of Texas System
The Board of Regents of The University of Texas System, a subsidiary of The University of Texas at Austin, is an American company located in Austin, TX. The firm oversees college activities.
Oncogene
Cancer immunotherapy
Oncology drugs
CanBas Co., Ltd. engages in pharmaceutical business. It focuses on the research and development of anti-cancer agent, drugs, and technologies which has minor impact on normal cell. Its technologies include drugs for the G2 check point and a screening system to find selective abrogates of the G2 check point. The company was founded by Takumi Kawabe and Masashi Suganuma on January 18, 2000 and is headquartered in Numazu, Japan.
Drug
Medicine
Pharmacy and Therapeutics
Biomedicine
Biotechnology
Side effect
Biopharmaceutical
Biophysics
Cell
Bionics
Blood cell
Cell signaling
Exosome
Clinical trial
Regents of the University of California
The University of California is the nation's best public university system, delivering top-notch research and innovation to California (and the world).
Pathology
Companion diagnostic
Canji, Inc., part of Merck & Co., Inc., is a company headquartered in San Diego, CA, specializing in medical laboratories. Schering-Plough Corp., now part of Merck & Co., Inc. acquired Canji, Inc. on February 02, 1996 for $54.50 million.
Discovers, develops, manufactures, and markets animal products and develops vaccines for animal and human health
Animal product
Botanical drug
Herb
Pioneer Hi-Bred International, Inc.
Syros Pharmaceuticals, Inc.
Syros Pharmaceuticals is a life sciences company that is focused on treating disease by mapping gene regulatory circuits and modulating the factors that regulate gene expression. Syros has pioneered world-leading gene control research and drug discovery capabilities with a proven ability to integrate disease biology and genomic data--a proficiency that is not well represented in pharmaceutical R&D.
Central to the Syros approach is a proprietary platform of carefully integrated assay technologies, bioinformatics, and biologic insights developed by members of Syros' senior leadership. While this scientific approach has applications in many therapeutic areas, Syros has demonstrated success initially in oncology, where it may help address numerous unmet medical needs.
Gene
Biology
Drug discovery
Oncology drugs
Prefilled Syringe
Autoinjector
Enzyme
Sewing needle
Injector
Biotechnology
Threonine
Syringe
Bioinformatics
Therapeutic Area
Abemaciclib
Cyclin-dependent kinase 9
Assay
Drug development
Ewing's sarcoma
Oncology
Centre National De La Recherche Scientif
Regents of The University of Michigan
http://www.regents.umich.edu
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Regents of The University of Michigan provides administers bonds on behalf of the University. The company is headquartered in Ann Arbor, MI.
ICOS Corporation is a biotechnology company that engages in the discovery, development, and commercialization of therapeutic products. It is engaged in the commercialization of treatments for unmet medical conditions, such as benign prostatic hyperplasia, hypertension, pulmonary arterial hypertension, cancer, and inflammatory diseases. It is the developer of a treatment known as Cialis (tadalafil), a product for the treatment of erectile dysfunction through its joint venture with Eli Lilly and Company in North America and Europe.
It is also engaged in contract manufacturing services for third parties. It is in a strategic alliance with Solvay Pharmaceuticals, Inc.
ICOS Corporation was established in 1989, based in Bothell, Washington. It is currently operated by Eli Lilly and Company.
Biotechnology
Medicine
Biomanufacturing
Tadalafil
Biomedicine
Cell culture
Hyperplasia
Tissue engineering
Monoclonal antibody
Lead compound
Lab-on-a-chip
High-throughput screening
Bioavailability
Contract research organization
Microfluidics
Drug discovery
TriPath Imaging, Inc. manufactures and markets diagnostic equipment and products for cervical cytology screening. The company’s products include microbial identification tests for differential detection and identification of the causative agents for vaginitis; ethanol based fixative systems to collect, preserve, hemolyze, transport, and transfer cytology specimens to a glass slide; slide profilers for prioritizing slides based on likelihood of abnormality to help cytotechnologists reduce false negatives;
Cervical cytology screening
Medicine
Vaginitis
Negative
Cytology
Abnormality
Ethanol
Riken Corp. engages in the manufacture and sale of engine and vehicular components. It operates through the Automotive and Machinery Parts, and Others segments. The Automotive and Machinery Parts segment deals with the company's core products such as piston rings, camshafts, seal rings for transmissions, high-grade cast iron products, and valve lifters. The Others segment includes plumbing equipment business, Electromagnetic Compatibility (EMC) business, and thermal engineering business, The company was founded by Masatoshi Okochi in November 1927 and is headquartered in Tokyo, Japan.
Social network
Tappet
Piston ring
Anechoic chamber
Thermal engineering
Camshaft
Industrial furnace
Cast iron
Piston
Core product
Radio frequency
Piping
Chagas disease
Fibrodysplasia ossificans progressiva
Flour treatment agent
Quantum cryptography
Database encryption
Cytogenetics
Primary cell
Hoechst AG produced specialty chemicals and pharmaceutical products. It products ranged in areas of heart cycle, thrombose, central nervous system, onkologie, diabetes, metabolic illnesses, internal medicine and vaccines. Founded in 1863, the company was headquartered in Frankfurt am Main, Germany.
Chemical engineering
Botanical drug
Herb
Central nervous system
Internal medicine
Cell Signaling Technology, Inc.
http://www.cellsignal.com
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Cell Signaling Technology, Inc. (CST) is a privately held company that develops and produces antibodies, ELISA kits, ChIP kits, proteomic kits, and other related reagents used to study the cell signaling pathways that impact human health. CST maintains an in-house research program, particularly in the area of cancer research, and has published scientific papers in many peer-reviewed journals.
Cell signaling
Medical equipment
Cell
Antibody
Immunohistochemistry
Cell signaling pathways
Biotechnology
Cancer research
Reagent
Histology
Flow cytometry
Pathology
Contract research organization
Immunofluorescence
Monoclonal antibody
Stem cell culture
Induced pluripotent stem cell
Microarray
Stem cell
Metabolomics
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